Low-dose cytokine-induced neutral ceramidase secretion from INS-1 cells via exosomes and its anti-apoptotic effect

FEBS Journal

Volumn 281, Issue 12, 2014, Pages 2861-2870

  Zhu, Qun ^a   Kang, Jian ^b   Miao, Heng ^a   Feng, Yamin ^a   Xiao, Lijun ^a   Hu, Zhigao ^c   Liao, Duan Fang ^d   Huang, Yan ^e   Jin, Junfei ^c,f   He, Songqing ^c,f  

^a THE SECOND AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

^b THE FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

^c GUILIN MEDICAL UNIVERSITY   (China)

^d HUNAN UNIVERSITY OF CHINESE MEDICINE   (China)

^e MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^f Guangxi Key Laboratory of Molecular Medicine in Liver Injury and Repair   (China)

Author keywords

apoptosis; cytokine; exosome; neutral ceramidase; cell

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 1BETA; NEUTRAL CERAMIDASE; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1 PHOSPHATE RECEPTOR; SPHINGOSINE 1 PHOSPHATE RECEPTOR 2; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL PROTECTION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME RELEASE; EXOSOME; INS 1 CELL LINE; MALE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RAT; SIGNAL TRANSDUCTION;

RATTUS;

APOPTOSIS; CYTOKINE; EXOSOME; NEUTRAL CERAMIDASE; Β-CELL;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELL LINE; CERAMIDASES; CULTURE MEDIA; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME-LINKED IMMUNOSORBENT ASSAY; EXOSOMES; ISLETS OF LANGERHANS; RATS;

EID: 84903635335     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.12826     Document Type: Article

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