-
1
-
-
12344291865
-
Bone morphogenetic proteins
-
Chen D, Zhao M, Mundy GR,. Bone morphogenetic proteins. Growth Factors. 2004; 22 (4): 233-41.
-
(2004)
Growth Factors
, vol.22
, Issue.4
, pp. 233-241
-
-
Chen, D.1
Zhao, M.2
Mundy, G.R.3
-
2
-
-
0034994419
-
Mullerian inhibiting substance signaling uses a bone morphogenetic protein (BMP)-like pathway mediated by ALK2 and induces SMAD6 expression
-
Clarke TR, Hoshiya Y, Yi SE, Liu X, Lyons KM, Donahoe PK,. Mullerian inhibiting substance signaling uses a bone morphogenetic protein (BMP)-like pathway mediated by ALK2 and induces SMAD6 expression. Mol Endocrinol. 2001; 15 (6): 946-59.
-
(2001)
Mol Endocrinol
, vol.15
, Issue.6
, pp. 946-959
-
-
Clarke, T.R.1
Hoshiya, Y.2
Yi, S.E.3
Liu, X.4
Lyons, K.M.5
Donahoe, P.K.6
-
3
-
-
55849145475
-
Transforming growth factor beta-induced Smad1/5 phosphorylation in epithelial cells is mediated by novel receptor complexes and is essential for anchorage-independent growth
-
Daly AC, Randall RA, Hill CS,. Transforming growth factor beta-induced Smad1/5 phosphorylation in epithelial cells is mediated by novel receptor complexes and is essential for anchorage-independent growth. Mol Cell Biol. 2008; 28 (22): 6889-902.
-
(2008)
Mol Cell Biol
, vol.28
, Issue.22
, pp. 6889-6902
-
-
Daly, A.C.1
Randall, R.A.2
Hill, C.S.3
-
4
-
-
77956516276
-
TGFbeta/BMP type i receptors ALK1 and ALK2 are essential for BMP9-induced osteogenic signaling in mesenchymal stem cells
-
Luo J, Tang M, Huang J, et al. TGFbeta/BMP type I receptors ALK1 and ALK2 are essential for BMP9-induced osteogenic signaling in mesenchymal stem cells. J Biol Chem. 2010; 285 (38): 29588-98.
-
(2010)
J Biol Chem
, vol.285
, Issue.38
, pp. 29588-29598
-
-
Luo, J.1
Tang, M.2
Huang, J.3
-
5
-
-
0033024513
-
Chondrogenic differentiation of murine C3H10T1/2 multipotential mesenchymal cells: II. Stimulation by bone morphogenetic protein-2 requires modulation of N-cadherin expression and function
-
Haas AR, Tuan RS,. Chondrogenic differentiation of murine C3H10T1/2 multipotential mesenchymal cells: II. Stimulation by bone morphogenetic protein-2 requires modulation of N-cadherin expression and function. Differentiation. 1999; 64 (2): 77-89.
-
(1999)
Differentiation
, vol.64
, Issue.2
, pp. 77-89
-
-
Haas, A.R.1
Tuan, R.S.2
-
6
-
-
17044364765
-
Bmpr1a and Bmpr1b have overlapping functions and are essential for chondrogenesis in vivo
-
Yoon BS, Ovchinnikov DA, Yoshii I, Mishina Y, Behringer RR, Lyons KM,. Bmpr1a and Bmpr1b have overlapping functions and are essential for chondrogenesis in vivo. Proc Natl Acad Sci USA. 2005; 102 (14): 5062-7.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.14
, pp. 5062-5067
-
-
Yoon, B.S.1
Ovchinnikov, D.A.2
Yoshii, I.3
Mishina, Y.4
Behringer, R.R.5
Lyons, K.M.6
-
7
-
-
0038687536
-
Developmental regulation of the growth plate
-
Kronenberg HM,. Developmental regulation of the growth plate. Nature. 2003; 423 (6937): 332-6.
-
(2003)
Nature
, vol.423
, Issue.6937
, pp. 332-336
-
-
Kronenberg, H.M.1
-
8
-
-
0036744820
-
Interaction of FGF, Ihh/Pthlh, and BMP signaling integrates chondrocyte proliferation and hypertrophic differentiation
-
Minina E, Kreschel C, Naski MC, Ornitz DM, Vortkamp A,. Interaction of FGF, Ihh/Pthlh, and BMP signaling integrates chondrocyte proliferation and hypertrophic differentiation. Dev Cell. 2002; 3 (3): 439-49.
-
(2002)
Dev Cell
, vol.3
, Issue.3
, pp. 439-449
-
-
Minina, E.1
Kreschel, C.2
Naski, M.C.3
Ornitz, D.M.4
Vortkamp, A.5
-
9
-
-
29144529005
-
BMP signaling stimulates cellular differentiation at multiple steps during cartilage development
-
Kobayashi T, Lyons KM, McMahon AP, Kronenberg HM,. BMP signaling stimulates cellular differentiation at multiple steps during cartilage development. Proc Natl Acad Sci USA. 2005; 102 (50): 18023-27.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.50
, pp. 18023-18027
-
-
Kobayashi, T.1
Lyons, K.M.2
McMahon, A.P.3
Kronenberg, H.M.4
-
10
-
-
33846067098
-
BMPs regulate multiple aspects of growth-plate chondrogenesis through opposing actions on FGF pathways
-
Yoon BS, Pogue R, Ovchinnikov DA, et al. BMPs regulate multiple aspects of growth-plate chondrogenesis through opposing actions on FGF pathways. Development. 2006; 133 (23): 4667-78.
-
(2006)
Development
, vol.133
, Issue.23
, pp. 4667-4678
-
-
Yoon, B.S.1
Pogue, R.2
Ovchinnikov, D.A.3
-
11
-
-
0033960316
-
The type i BMP receptor BMPRIB is required for chondrogenesis in the mouse limb
-
Yi SE, Daluiski A, Pederson R, Rosen V, Lyons KM,. The type I BMP receptor BMPRIB is required for chondrogenesis in the mouse limb. Development. 2000; 127 (3): 621-30.
-
(2000)
Development
, vol.127
, Issue.3
, pp. 621-630
-
-
Yi, S.E.1
Daluiski, A.2
Pederson, R.3
Rosen, V.4
Lyons, K.M.5
-
12
-
-
0042978771
-
ALK2 functions as a BMP type i receptor and induces Indian hedgehog in chondrocytes during skeletal development
-
Zhang D, Schwarz EM, Rosier RN, Zuscik MJ, Puzas JE, O'Keefe RJ,. ALK2 functions as a BMP type I receptor and induces Indian hedgehog in chondrocytes during skeletal development. J Bone Miner Res. 2003; 18 (9): 1593-604.
-
(2003)
J Bone Miner Res
, vol.18
, Issue.9
, pp. 1593-1604
-
-
Zhang, D.1
Schwarz, E.M.2
Rosier, R.N.3
Zuscik, M.J.4
Puzas, J.E.5
O'Keefe, R.J.6
-
13
-
-
0032718990
-
Roles of bone morphogenetic protein type i receptors and Smad proteins in osteoblast and chondroblast differentiation
-
Fujii M, Takeda K, Imamura T, et al. Roles of bone morphogenetic protein type I receptors and Smad proteins in osteoblast and chondroblast differentiation. Mol Biol Cell. 1999; 10 (11): 3801-13.
-
(1999)
Mol Biol Cell
, vol.10
, Issue.11
, pp. 3801-3813
-
-
Fujii, M.1
Takeda, K.2
Imamura, T.3
-
14
-
-
0002961059
-
Heterotopic ossification: Two rare forms and what they can teach us
-
Kaplan FS, Hahn GV, Zasloff MA,. Heterotopic ossification: Two rare forms and what they can teach us. J Am Acad Orthop Surg. 1994; 2 (5): 288-96.
-
(1994)
J Am Acad Orthop Surg
, vol.2
, Issue.5
, pp. 288-296
-
-
Kaplan, F.S.1
Hahn, G.V.2
Zasloff, M.A.3
-
15
-
-
33646348736
-
A recurrent mutation in the BMP type i receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva
-
Shore EM, Xu M, Feldman GJ, et al. A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva. Nat Genet. 2006; 38 (5): 525-7.
-
(2006)
Nat Genet
, vol.38
, Issue.5
, pp. 525-527
-
-
Shore, E.M.1
Xu, M.2
Feldman, G.J.3
-
16
-
-
70449366408
-
The fibrodysplasia ossificans progressiva R206H ACVR1 mutation activates BMP-independent chondrogenesis and zebrafish embryo ventralization
-
Shen Q, Little SC, Xu M, et al. The fibrodysplasia ossificans progressiva R206H ACVR1 mutation activates BMP-independent chondrogenesis and zebrafish embryo ventralization. J Clin Invest. 2009; 119 (11): 3462-72.
-
(2009)
J Clin Invest
, vol.119
, Issue.11
, pp. 3462-3472
-
-
Shen, Q.1
Little, S.C.2
Xu, M.3
-
17
-
-
78650018824
-
Conversion of vascular endothelial cells into multipotent stem-like cells
-
Medici D, Shore EM, Lounev VY, Kaplan FS, Kalluri R, Olsen BR,. Conversion of vascular endothelial cells into multipotent stem-like cells. Nat Med. 2010; 16 (12): 1400-6.
-
(2010)
Nat Med
, vol.16
, Issue.12
, pp. 1400-1406
-
-
Medici, D.1
Shore, E.M.2
Lounev, V.Y.3
Kaplan, F.S.4
Kalluri, R.5
Olsen, B.R.6
-
18
-
-
77953497987
-
ALK2 R206H mutation linked to fibrodysplasia ossificans progressiva confers constitutive activity to the BMP type i receptor and sensitizes mesenchymal cells to BMP-induced osteoblast differentiation and bone formation
-
van Dinther M, Visser N, de Gorter DJ, et al. ALK2 R206H mutation linked to fibrodysplasia ossificans progressiva confers constitutive activity to the BMP type I receptor and sensitizes mesenchymal cells to BMP-induced osteoblast differentiation and bone formation. J Bone Miner Res. 2010; 25 (6): 1208-15.
-
(2010)
J Bone Miner Res
, vol.25
, Issue.6
, pp. 1208-1215
-
-
Van Dinther, M.1
Visser, N.2
De Gorter, D.J.3
-
19
-
-
12944265540
-
Col2a1-directed expression of Cre recombinase in differentiating chondrocytes in transgenic mice
-
Ovchinnikov DA, Deng JM, Ogunrinu G, Behringer RR,. Col2a1-directed expression of Cre recombinase in differentiating chondrocytes in transgenic mice. Genesis. 2000; 26 (2): 145-6.
-
(2000)
Genesis
, vol.26
, Issue.2
, pp. 145-146
-
-
Ovchinnikov, D.A.1
Deng, J.M.2
Ogunrinu, G.3
Behringer, R.R.4
-
20
-
-
0036193068
-
Generation of Bmpr/Alk3 conditional knockout mice
-
Mishina Y, Hanks MC, Miura S, Tallquist MD, Behringer RR,. Generation of Bmpr/Alk3 conditional knockout mice. Genesis. 2002; 32 (2): 69-72.
-
(2002)
Genesis
, vol.32
, Issue.2
, pp. 69-72
-
-
Mishina, Y.1
Hanks, M.C.2
Miura, S.3
Tallquist, M.D.4
Behringer, R.R.5
-
21
-
-
1642392579
-
Craniofacial defects in mice lacking BMP type i receptor Alk2 in neural crest cells
-
Dudas M, Sridurongrit S, Nagy A, Okazaki K, Kaartinen V,. Craniofacial defects in mice lacking BMP type I receptor Alk2 in neural crest cells. Mech Dev. 2004; 121 (2): 173-82.
-
(2004)
Mech Dev
, vol.121
, Issue.2
, pp. 173-182
-
-
Dudas, M.1
Sridurongrit, S.2
Nagy, A.3
Okazaki, K.4
Kaartinen, V.5
-
22
-
-
66349117431
-
BMP canonical Smad signaling through Smad1 and Smad5 is required for endochondral bone formation
-
Retting KN, Song B, Yoon BS, Lyons KM,. BMP canonical Smad signaling through Smad1 and Smad5 is required for endochondral bone formation. Development. 2009; 136 (7): 1093-104.
-
(2009)
Development
, vol.136
, Issue.7
, pp. 1093-1104
-
-
Retting, K.N.1
Song, B.2
Yoon, B.S.3
Lyons, K.M.4
-
24
-
-
80053189525
-
Smad6 is essential to limit BMP signaling during cartilage development
-
Estrada KD, Retting KN, Chin AM, Lyons KM,. Smad6 is essential to limit BMP signaling during cartilage development. J Bone Miner Res. 2011; 26 (10): 2498-510.
-
(2011)
J Bone Miner Res
, vol.26
, Issue.10
, pp. 2498-2510
-
-
Estrada, K.D.1
Retting, K.N.2
Chin, A.M.3
Lyons, K.M.4
-
25
-
-
84884820709
-
Smad7 regulates terminal maturation of chondrocytes in the growth plate
-
Estrada KD, Wang W, Retting KN, et al. Smad7 regulates terminal maturation of chondrocytes in the growth plate. Dev Biol. 2013; 382 (2): 375-84.
-
(2013)
Dev Biol
, vol.382
, Issue.2
, pp. 375-384
-
-
Estrada, K.D.1
Wang, W.2
Retting, K.N.3
-
26
-
-
0029087923
-
Expression of type i and type IB receptors for activin in midgestation mouse embryos suggests distinct functions in organogenesis
-
Verschueren K, Dewulf N, Goumans MJ, et al. Expression of type I and type IB receptors for activin in midgestation mouse embryos suggests distinct functions in organogenesis. Mech Dev. 1995; 52 (1): 109-23.
-
(1995)
Mech Dev
, vol.52
, Issue.1
, pp. 109-123
-
-
Verschueren, K.1
Dewulf, N.2
Goumans, M.J.3
-
27
-
-
29244452110
-
Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification
-
Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A,. Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005; 6 (1): 102-9.
-
(2005)
Gene Expr Patterns
, vol.6
, Issue.1
, pp. 102-109
-
-
Minina, E.1
Schneider, S.2
Rosowski, M.3
Lauster, R.4
Vortkamp, A.5
-
28
-
-
0034001050
-
The ActR-I activin receptor protein is expressed in notochord, lens placode and pituitary primordium cells in the mouse embryo
-
Yoshikawa SI, Aota S, Shirayoshi Y, Okazaki K,. The ActR-I activin receptor protein is expressed in notochord, lens placode and pituitary primordium cells in the mouse embryo. Mech Dev. 2000; 91 (1-2): 439-44.
-
(2000)
Mech Dev
, vol.91
, Issue.12
, pp. 439-444
-
-
Yoshikawa, S.I.1
Aota, S.2
Shirayoshi, Y.3
Okazaki, K.4
-
29
-
-
0033565488
-
Immunolocalization of bone morphogenetic protein and its receptors in degeneration of intervertebral disc
-
Takae R, Matsunaga S, Origuchi N, et al. Immunolocalization of bone morphogenetic protein and its receptors in degeneration of intervertebral disc. Spine (Phila Pa 1976). 1999; 24 (14): 1397-401.
-
(1999)
Spine (Phila Pa 1976)
, vol.24
, Issue.14
, pp. 1397-1401
-
-
Takae, R.1
Matsunaga, S.2
Origuchi, N.3
-
30
-
-
16844368696
-
A homozygous BMPR1B mutation causes a new subtype of acromesomelic chondrodysplasia with genital anomalies
-
Demirhan O, Turkmen S, Schwabe GC, et al. A homozygous BMPR1B mutation causes a new subtype of acromesomelic chondrodysplasia with genital anomalies. J Med Genet. 2005; 42 (4): 314-7.
-
(2005)
J Med Genet
, vol.42
, Issue.4
, pp. 314-317
-
-
Demirhan, O.1
Turkmen, S.2
Schwabe, G.C.3
-
31
-
-
33751317476
-
A novel R486Q mutation in BMPR1B resulting in either a brachydactyly type C/symphalangism-like phenotype or brachydactyly type A2
-
Lehmann K, Seemann P, Boergermann J, et al. A novel R486Q mutation in BMPR1B resulting in either a brachydactyly type C/symphalangism-like phenotype or brachydactyly type A2. Eur J Hum Genet. 2006; 14 (12): 1248-54.
-
(2006)
Eur J Hum Genet
, vol.14
, Issue.12
, pp. 1248-1254
-
-
Lehmann, K.1
Seemann, P.2
Boergermann, J.3
-
32
-
-
84864115359
-
An Acvr1 R206H knock-in mouse has fibrodysplasia ossificans progressiva
-
Chakkalakal SA, Zhang D, Culbert AL, et al. An Acvr1 R206H knock-in mouse has fibrodysplasia ossificans progressiva. J Bone Miner Res. 2012; 27 (8): 1746-56.
-
(2012)
J Bone Miner Res
, vol.27
, Issue.8
, pp. 1746-1756
-
-
Chakkalakal, S.A.1
Zhang, D.2
Culbert, A.L.3
-
33
-
-
25844529319
-
Developmental anomalies of the cervical spine in patients with fibrodysplasia ossificans progressiva are distinctly different from those in patients with Klippel-Feil syndrome: Clues from the BMP signaling pathway
-
Schaffer AA, Kaplan FS, Tracy MR, et al. Developmental anomalies of the cervical spine in patients with fibrodysplasia ossificans progressiva are distinctly different from those in patients with Klippel-Feil syndrome: clues from the BMP signaling pathway. Spine (Phila Pa 1976). 2005; 30 (12): 1379-85.
-
(2005)
Spine (Phila Pa 1976)
, vol.30
, Issue.12
, pp. 1379-1385
-
-
Schaffer, A.A.1
Kaplan, F.S.2
Tracy, M.R.3
-
34
-
-
61649084689
-
Classic and atypical fibrodysplasia ossificans progressiva (FOP) phenotypes are caused by mutations in the bone morphogenetic protein (BMP) type i receptor ACVR1
-
Kaplan FS, Xu M, Seemann P, et al. Classic and atypical fibrodysplasia ossificans progressiva (FOP) phenotypes are caused by mutations in the bone morphogenetic protein (BMP) type I receptor ACVR1. Hum Mutat. 2009; 30 (3): 379-90.
-
(2009)
Hum Mutat
, vol.30
, Issue.3
, pp. 379-390
-
-
Kaplan, F.S.1
Xu, M.2
Seemann, P.3
-
35
-
-
0017605117
-
A radiographic study of the human fetal spine. 2. The sequence of development of ossification centres in the vertebral column
-
Bagnall KM, Harris PF, Jones PR,. A radiographic study of the human fetal spine. 2. The sequence of development of ossification centres in the vertebral column. J Anat. 1977; 124 (Pt 3): 791-802.
-
(1977)
J Anat
, vol.124
, pp. 791-802
-
-
Bagnall, K.M.1
Harris, P.F.2
Jones, P.R.3
-
36
-
-
0021964295
-
Developmental stability in the mouse vertebral column
-
Sofaer JA,. Developmental stability in the mouse vertebral column. J Anat. 1985; 140 (Pt 1): 131-41.
-
(1985)
J Anat
, vol.140
, pp. 131-141
-
-
Sofaer, J.A.1
-
37
-
-
84861234756
-
The face signature of fibrodysplasia ossificans progressiva
-
Hammond P, Suttie M, Hennekam RC, Allanson J, Shore EM, Kaplan FS,. The face signature of fibrodysplasia ossificans progressiva. Am J Med Genet A. 2012; 158A (6): 1368-80.
-
(2012)
Am J Med Genet A
, vol.158 A
, Issue.6
, pp. 1368-1380
-
-
Hammond, P.1
Suttie, M.2
Hennekam, R.C.3
Allanson, J.4
Shore, E.M.5
Kaplan, F.S.6
-
38
-
-
70350389854
-
The type i BMP receptors, Bmpr1a and Acvr1, activate multiple signaling pathways to regulate lens formation
-
Rajagopal R, Huang J, Dattilo LK, et al. The type I BMP receptors, Bmpr1a and Acvr1, activate multiple signaling pathways to regulate lens formation. Dev Biol. 2009; 335 (2): 305-16.
-
(2009)
Dev Biol
, vol.335
, Issue.2
, pp. 305-316
-
-
Rajagopal, R.1
Huang, J.2
Dattilo, L.K.3
-
39
-
-
0033377614
-
Pax1 and Pax9 synergistically regulate vertebral column development
-
Peters H, Wilm B, Sakai N, Imai K, Maas R, Balling R,. Pax1 and Pax9 synergistically regulate vertebral column development. Development. 1999; 126 (23): 5399-408.
-
(1999)
Development
, vol.126
, Issue.23
, pp. 5399-5408
-
-
Peters, H.1
Wilm, B.2
Sakai, N.3
Imai, K.4
Maas, R.5
Balling, R.6
-
40
-
-
0036798521
-
Immunohistochemical localization of osteogenetic protein (OP-1) and its receptors in rabbit articular cartilage
-
Muehleman C, Kuettner KE, Rueger DC, Ten Dijke, Chubinskaya P,. Immunohistochemical localization of osteogenetic protein (OP-1) and its receptors in rabbit articular cartilage. J Histochem Cytochem. 2002; 50 (10): 1341-50.
-
(2002)
J Histochem Cytochem
, vol.50
, Issue.10
, pp. 1341-1350
-
-
Muehleman, C.1
Kuettner, K.E.2
Rueger, D.C.3
Ten, D.4
Chubinskaya, P.5
-
41
-
-
84870041193
-
Fibrodysplasia ossificans progressiva: Mechanisms and models of skeletal metamorphosis
-
Kaplan FS, Chakkalakal SA, Shore EM,. Fibrodysplasia ossificans progressiva: mechanisms and models of skeletal metamorphosis. Dis Model Mech. 2012; 5 (6): 756-62.
-
(2012)
Dis Model Mech
, vol.5
, Issue.6
, pp. 756-762
-
-
Kaplan, F.S.1
Chakkalakal, S.A.2
Shore, E.M.3
-
42
-
-
80051924689
-
Cell cycle arrest in node cells governs ciliogenesis at the node to break left-right symmetry
-
Komatsu Y, Kaartinen V, Mishina Y,. Cell cycle arrest in node cells governs ciliogenesis at the node to break left-right symmetry. Development. 2011; 138 (18): 3915-20.
-
(2011)
Development
, vol.138
, Issue.18
, pp. 3915-3920
-
-
Komatsu, Y.1
Kaartinen, V.2
Mishina, Y.3
|