Identification and characterization of human Rad51 inhibitors by screening of an existing drug library

Biochemical Pharmacology

Volumn 91, Issue 3, 2014, Pages 293-300

  Normand, Anaïs ^a   Rivière, Emmanuelle ^a   Renodon Cornière, Axelle ^a  

^a UNIVERSITÉ DE NANTES   (France)

Author keywords

Anticancer agent; Homologous recombination; Inhibitor; Multidrug resistance; Rad51

Indexed keywords

ADENOSINE TRIPHOSPHATE; CHICAGO SKY BLUE; NUCLEOPROTEIN; OLIGONUCLEOTIDE; PROTEIN INHIBITOR; RAD51 PROTEIN; SINGLE STRANDED DNA; UNCLASSIFIED DRUG; MOLECULAR LIBRARY; PONTAMINE SKY BLUE; RAD51 PROTEIN, HUMAN; TRYPAN BLUE;

ARTICLE; CHEMICAL ANALYSIS; CHEMICAL STRUCTURE; DNA DAMAGE; DNA REPAIR; ELECTROPHORESIS; HOMOLOGOUS RECOMBINATION; IC50; IN VITRO STUDY; MOLECULAR LIBRARY; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; ANTAGONISTS AND INHIBITORS; CHEMISTRY; DRUG EFFECTS; DRUG SCREENING; HUMAN; METABOLISM; PHARMACOLOGY; PROCEDURES; TWO DIMENSIONAL GEL ELECTROPHORESIS;

ADENOSINE TRIPHOSPHATE; DNA REPAIR; DNA, SINGLE-STRANDED; DRUG EVALUATION, PRECLINICAL; ELECTROPHORESIS; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; HOMOLOGOUS RECOMBINATION; HUMANS; INHIBITORY CONCENTRATION 50; RAD51 RECOMBINASE; SMALL MOLECULE LIBRARIES; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPAN BLUE;

EID: 84925438153     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2014.07.033     Document Type: Article

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