Targeting human Rad51 by specific DNA aptamers induces inhibition of homologous recombination

Enfermedades Infecciosas y Microbiologia Clinica

Volumn 28, Issue SUPPL. 3, 2010, Pages 1832-1838

  Martinez, Susan F ^a   Renodon Cornire, Axelle ^a   Nomme, Julian ^a   Eveillard, Damien ^a   Fleury, Fabrice ^a   Takahashi, Masayuki ^a   Weigel, Pierre ^a  

^a UNIVERSITÉ DE NANTES   (France)

Author keywords

Aptamer; DNA strand exchange; Homologous recombination; Rad51 inhibitor

Indexed keywords

ADENOSINE TRIPHOSPHATE; APTAMER; NUCLEOTIDYLTRANSFERASE INHIBITOR; OLIGONUCLEOTIDE 45; OLIGONUCLEOTIDE A13; OLIGONUCLEOTIDE A30; OLIGONUCLEOTIDE A47; OLIGONUCLEOTIDE A48; OLIGONUCLEOTIDE A7; OLIGONUCLEOTIDE A77; OLIGONUCLEOTIDE A79; OLIGONUCLEOTIDE A90; RAD51 PROTEIN; RECA PROTEIN; RECOMBINASE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; CIRCULAR DICHROISM; DNA STRAND; DNA STRUCTURE; ENZYME ACTIVITY; HOMOLOGOUS RECOMBINATION; NONHUMAN; PROTEIN BINDING; DNA BINDING;

ADENOSINE TRIPHOSPHATE; APTAMERS, NUCLEOTIDE; BINDING, COMPETITIVE; CIRCULAR DICHROISM; DNA; HUMANS; KINETICS; NUCLEIC ACID CONFORMATION; OLIGONUCLEOTIDES; PRINCIPAL COMPONENT ANALYSIS; PROTEIN BINDING; RAD51 RECOMBINASE; REC A RECOMBINASES; RECOMBINATION, GENETIC; SELEX APTAMER TECHNIQUE; SPECTROPHOTOMETRY;

PROKARYOTA;

EID: 78650236477     PISSN: 0213005X     EISSN: 15781852     Source Type: Journal    
DOI: 10.1016/j.biochi.2010.08.006     Document Type: Article

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