Identification of specific inhibitors of human RAD51 recombinase using high-throughput screening

ACS Chemical Biology

Volumn 6, Issue 6, 2011, Pages 628-635

  Huang, Fei ^a   Motlekar, Nuzhat A ^b   Burgwin, Chelsea M ^a   Napper, Andrew D ^b   Diamond, Scott L ^a,b   Mazin, Alexander V ^a  

^a DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPOUND A03; COMPOUND A04; COMPOUND A05; COMPOUND A06; COMPOUND A07; COMPOUND A08; COMPOUND A09; COMPOUND A10; COMPOUND A11; COMPOUND A12; COMPOUND A13; COMPOUND A14; COMPOUND A15; COMPOUND B01; COMPOUND B02; COMPOUND B02 3A; COMPOUND B02 3B; COMPOUND B04; COMPOUND B05; NUCLEOTIDYLTRANSFERASE INHIBITOR; RAD51 PROTEIN; RAD51 RECOMBINASE INHIBITOR; RAD54 PROTEIN; RECA PROTEIN; UNCLASSIFIED DRUG;

CONFERENCE PAPER; DNA DETERMINATION; DNA REPAIR; DNA STRAND; DRUG IDENTIFICATION; FLUORESCENCE RESONANCE ENERGY TRANSFER; HIGH THROUGHPUT SCREENING; IC 50; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ENZYME INHIBITORS; FLUORESCENCE RESONANCE ENERGY TRANSFER; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; MOLECULAR STRUCTURE; QUINAZOLINONES; RAD51 RECOMBINASE; SMALL MOLECULE LIBRARIES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 79961077772     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb100428c     Document Type: Conference Paper

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