Calcium activation of BKCa potassium channels lacking the calcium bowl and RCK domains

Nature

Volumn 420, Issue 6915, 2002, Pages 499-502

  Piskorowski, Rebecca ^a   Aldrich, Richard W ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CELLS; MUSCLE; NEUROLOGY; PHYSIOLOGY; POTASSIUM;

NEUROTRANSMITTERS;

BIOCHEMISTRY;

CALCIUM ACTIVATED POTASSIUM CHANNEL;

CALCIUM; POTASSIUM;

ARTICLE; CALCIUM BINDING; CALCIUM CELL LEVEL; CARBOXY TERMINAL SEQUENCE; MEMBRANE DEPOLARIZATION; MEMBRANE POTENTIAL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN;

AMINO ACID MOTIFS; ANIMALS; BINDING SITES; CALCIUM; CELL LINE; ELECTRIC CONDUCTIVITY; HUMANS; ION CHANNEL GATING; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; MICE; MUTATION; OOCYTES; POTASSIUM; POTASSIUM CHANNELS, CALCIUM-ACTIVATED; PROTEIN STRUCTURE, TERTIARY; XENOPUS LAEVIS;

EID: 0037028130     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature01199     Document Type: Article

References (30)

1. Nelson, M. T. et al. Relaxation of arterial smooth, muscle by calcium sparks. Science 270, 633-637 (1995).
2. Lewis, R. S. & Hudspeth, A. J. Voltage- and ion-dependent conductances in solitary vertebrate hair cells. Nature 304, 538-541 (1983).
3. Robitaille, R., Garcia, M. L., Kaczorowski, G. J. & Charlton, M. P. Functional colocalization of calcium and calcium-gated potassium channels in control of transmitter release. Neuron 11, 645-65 (1993).
4. Crawford, A. C. & Fettiplace, R. An electrical tuning mechanism in turtle cochlear hair cells. J. Physiol. (Lond.) 312, 377-412 (1981).
5. + channels. J. Gen. Physiol. 109, 647-673 (1997).
6. + channel (hslo). Proc. Natl. Acad. Sci. USA 94, 5427-5431 (1997).
7. 2+. J. Gen. Physiol. 114, 277-304 (1999).
8. Talukder, G. & Aldrich, R. W. Complex voltage-dependent behavior of single unliganded calciumsensitive potassium channels. Biophys. J. 78, 761-772 (2000).
9. 2+-activated potassium channels by retaining the gating in the bursting states. J. Gen. Physiol. 113, 425-440 (1999).
10. + channels with large unitary conductance in chromaffin cell membranes. Nature 291, 497-500 (1981).
11. + currents in rat muscle cell culture. Nature 293, 471-474 (1981).
12. + channel. J. Gen. Physiol 110, 257-281 (1997).
13. 2+ suggest a two-tiered allosteric gating mechanism. J. Gen. Physiol 114, 93-124 (1999).
14. + channels described by a two-tiered allosteric gating mechanism. J. Gen. Physiol. 116, 75-99 (2000).
15. Schreiber, M. & Salkoff, L. A novel calcium-sensing domain in the BK channel. Biophys. J. 73, 1355-1363 (1997).
16. Schreiber, M., Yuan, A. & Salkoff, L. Transplantable sites confer calcium sensitivity to BK channels. Nature Neurosci. 2, 416-421 (1999).
17. Ca channels determined by a separable domain. Neuron 13, 671-681 (1994).
18. 2+-dependent activation. Proc. Natl. Acad. Sci. USA 98, 4776-4781 (2001).
19. + channel. J. Physiol (Lond.) 533, 681-695 (2001).
20. 2+ sensitivity. J. Gen. Physiol. 120, 173-189 (2002).
21. Xia, X. M., Zeng, X. & Lingle, C. J. Multiple regulatory sites in large-conductance calcium-activated potassium channels. Nature 418, 880-884 (2002).
22. Jiang, Y. et al. Crystal structure and mechanism of a calcium-gated potassium channel. Nature 417, 515-522 (2002).
23. + channel α-subunit in Madin-Darby canine kidney cells is independent of N-glycosylation. Proc. Natl. Acad. Sci. USA 97, 13114-13119 (2000).
24. Ca channels. Neuron 32, 13-23 (2001).
25. 2+-activated K+ channels. Neuropharmacology 35, 1017-1022 (1996).
26. Shen, K. Z. et al. Tetraethylammonium block of Slowpoke calcium-activated potassium channels expressed in Xenopus oocytes: evidence for tetrameric channel formation. Pflugers Arch. 426, 440-445 (1994).
27. 2+. Proc. Natl. Acad. Sci. USA 99, 11441-11446 (2002).
28. Zhu, G., Zhang, Y., Xu, H. & Jiang, C. Identification of endogenous outward currents in the human embryonic kidney (HEK 293) cell line. J. Neurosci. Methods 81, 73-83 (1998).
29. Colquhoun, D. Binding, gating, affinity and efficacy: The interpretation of structure-activity relationships for agonists and of the effects of mutating receptors. Br. J. Pharmacol. 125, 924-947 (1998).
30. 2+ binding and channel opening in large conductance (BK) potassium channels. J. Gen. Physiol. 120, 267-305 (2002).