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Angewandte Chemie - International Edition

Volumn 53, Issue 38, 2014, Pages 10124-10128

Mapping polyamide-DNA interactions in human cells reveals a new design strategy for effective targeting of genomic sites

(4) Erwin, Graham S a Bhimsaria, Devesh a Eguchi, Asuka a Ansari, Aseem Z a

a UNIVERSITY OF WISCONSIN MADISON (United States)

Author keywords

chemoinformatics; COSMIC; genome targeting; molecular recognition; polyamides

Indexed keywords

BIOINFORMATICS; CROSSLINKING; DNA; DNA SEQUENCES; GENES; MOLECULAR RECOGNITION; MOLECULES; POLYAMIDES;

BINDING ENERGETICS; BIOINFORMATIC ANALYSIS; CHEMOINFORMATICS; COSMIC; COVALENT CROSSLINKING; HIGH-AFFINITY SITES; PERSONALIZED MEDICINES; SYNTHETIC MOLECULES;

BINDING SITES;

DNA; NYLON;

BINDING SITE; BIOLOGY; CHEMICAL STRUCTURE; CHEMISTRY; DRUG DESIGN; DRUG EFFECTS; GENETICS; GENOME; GENOMICS; HEK293 CELL LINE; HUMAN; SYNTHESIS;

BINDING SITES; COMPUTATIONAL BIOLOGY; DNA; DRUG DESIGN; GENOME; GENOMICS; HEK293 CELLS; HUMANS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; NYLONS;

EID: 84925392393 PISSN: 14337851 EISSN: 15213773 Source Type: Journal
DOI: 10.1002/anie.201405497 Document Type: Article

Times cited : (25)

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