메뉴 건너뛰기




Volumn 26, Issue 4, 2015, Pages 345-350

α-Tocopherol suppresses antiangiogenic effect of δ-tocotrienol in human umbilical vein endothelial cells

Author keywords

Angiogenesis; HUVEC; Tocopherol; Tocotrienol; VEGF

Indexed keywords

ALPHA TOCOPHEROL; ALPHA TOCOTRIENOL; CASPASE; CASPASE 3; DELTA TOCOTRIENOL; PROTEIN P21; PROTEIN P27; UNCLASSIFIED DRUG; ANGIOGENESIS INHIBITOR; CASP3 PROTEIN, HUMAN; CASP9 PROTEIN, HUMAN; CASPASE 9; CDKN1A PROTEIN, HUMAN; CDKN1B PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLIN DEPENDENT KINASE INHIBITOR 1B; PROTEIN KINASE B; TOCOPHEROL; TOCOTRIENOL, DELTA; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2, HUMAN; VASCULOTROPIN RECEPTOR 2;

EID: 84925297659     PISSN: 09552863     EISSN: 18734847     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2014.11.010     Document Type: Article
Times cited : (13)

References (26)
  • 1
    • 0242624629 scopus 로고    scopus 로고
    • Molecular basis of angiogenesis and cancer
    • Tonini T., Rossi F., Claudio P.P. Molecular basis of angiogenesis and cancer. Oncogene 2003, 22:6549-6556.
    • (2003) Oncogene , vol.22 , pp. 6549-6556
    • Tonini, T.1    Rossi, F.2    Claudio, P.P.3
  • 2
    • 84859575611 scopus 로고    scopus 로고
    • Anti-angiogenesis therapy in cancer: current challenges and future perspectives
    • Shojaei F. Anti-angiogenesis therapy in cancer: current challenges and future perspectives. Cancer Lett 2012, 320:130-137.
    • (2012) Cancer Lett , vol.320 , pp. 130-137
    • Shojaei, F.1
  • 3
    • 79959958353 scopus 로고    scopus 로고
    • Inhibition of tumor angiogenesis by antibodies, synthetic small molecules and natural products
    • Wahl O., Oswald M., Tretzel L., Herres E., Arend J., Efferth T. Inhibition of tumor angiogenesis by antibodies, synthetic small molecules and natural products. Curr Med Chem 2011, 18:3136-3155.
    • (2011) Curr Med Chem , vol.18 , pp. 3136-3155
    • Wahl, O.1    Oswald, M.2    Tretzel, L.3    Herres, E.4    Arend, J.5    Efferth, T.6
  • 4
    • 84873516380 scopus 로고    scopus 로고
    • Vitamin E δ-tocotrienol induces p27(Kip1)-dependent cell-cycle arrest in pancreatic cancer cells via an E2F-1-dependent mechanism
    • Hodul P.J., Dong Y., Husain K., Pimiento J.M., Chen J., Zhang A., et al. Vitamin E δ-tocotrienol induces p27(Kip1)-dependent cell-cycle arrest in pancreatic cancer cells via an E2F-1-dependent mechanism. PLoS One 2013, 8:e52526. 10.1371/journal.pone.0052526.
    • (2013) PLoS One , vol.8
    • Hodul, P.J.1    Dong, Y.2    Husain, K.3    Pimiento, J.M.4    Chen, J.5    Zhang, A.6
  • 5
    • 84859834841 scopus 로고    scopus 로고
    • First evidence that γ-tocotrienol inhibits the growth of human gastric cancer and chemosensitizes it to capecitabine in a xenograft mouse model through the modulation of NF-κB pathway
    • Manu K.A., Shanmugam M.K., Ramachandran L., Li F., Fong C.W., Kumar A.P., et al. First evidence that γ-tocotrienol inhibits the growth of human gastric cancer and chemosensitizes it to capecitabine in a xenograft mouse model through the modulation of NF-κB pathway. Clin Cancer Res 2012, 18:2220-2229.
    • (2012) Clin Cancer Res , vol.18 , pp. 2220-2229
    • Manu, K.A.1    Shanmugam, M.K.2    Ramachandran, L.3    Li, F.4    Fong, C.W.5    Kumar, A.P.6
  • 7
    • 55949100543 scopus 로고    scopus 로고
    • Tocotrienol inhibits secretion of angiogenic factors from human colorectal adenocarcinoma cells by suppressing hypoxia-inducible factor-1α
    • Shibata A., Nakagawa K., Sookwong P., Tsuduki T., Tomita S., Shirakawa H., et al. Tocotrienol inhibits secretion of angiogenic factors from human colorectal adenocarcinoma cells by suppressing hypoxia-inducible factor-1α. J Nutr 2008, 138:2136-2142.
    • (2008) J Nutr , vol.138 , pp. 2136-2142
    • Shibata, A.1    Nakagawa, K.2    Sookwong, P.3    Tsuduki, T.4    Tomita, S.5    Shirakawa, H.6
  • 8
    • 0030897729 scopus 로고    scopus 로고
    • Inhibition of proliferation of estrogen receptor-negative MDA-MB-435 and -positive MCF-7 human breast cancer cells by palm oil tocotrienols and tamoxifen, alone and in combination
    • Guthrie N., Gapor A., Chambers A.F., Carroll K.K. Inhibition of proliferation of estrogen receptor-negative MDA-MB-435 and -positive MCF-7 human breast cancer cells by palm oil tocotrienols and tamoxifen, alone and in combination. J Nutr 1997, 127:544S-548S.
    • (1997) J Nutr , vol.127 , pp. 544S-548S
    • Guthrie, N.1    Gapor, A.2    Chambers, A.F.3    Carroll, K.K.4
  • 9
    • 63049131505 scopus 로고    scopus 로고
    • Inhibition of proliferation and induction of apoptosis by γ-tocotrienol in human colon carcinoma HT-29 cells
    • Xu W.L., Liu J.R., Liu H.K., Qi G.Y., Sun X.R., Sun W.G., et al. Inhibition of proliferation and induction of apoptosis by γ-tocotrienol in human colon carcinoma HT-29 cells. Nutrition 2009, 25:555-566.
    • (2009) Nutrition , vol.25 , pp. 555-566
    • Xu, W.L.1    Liu, J.R.2    Liu, H.K.3    Qi, G.Y.4    Sun, X.R.5    Sun, W.G.6
  • 11
    • 77950300003 scopus 로고    scopus 로고
    • Id1, inhibitor of differentiation, is a key protein mediating anti-tumor responses of γ-tocotrienol in breast cancer cells
    • Yap W.N., Zaiden N., Tan Y.L., Ngoh C.P., Zhang X.W., Wong Y.C., et al. Id1, inhibitor of differentiation, is a key protein mediating anti-tumor responses of γ-tocotrienol in breast cancer cells. Cancer Lett 2010, 291:187-199.
    • (2010) Cancer Lett , vol.291 , pp. 187-199
    • Yap, W.N.1    Zaiden, N.2    Tan, Y.L.3    Ngoh, C.P.4    Zhang, X.W.5    Wong, Y.C.6
  • 13
    • 77955482300 scopus 로고    scopus 로고
    • α-Tocopherol attenuates the cytotoxic effect of δ-tocotrienol in human colorectal adenocarcinoma cells
    • Shibata A., Nakagawa K., Sookwong P., Tsuduki T., Asai A., Miyazawa T. α-Tocopherol attenuates the cytotoxic effect of δ-tocotrienol in human colorectal adenocarcinoma cells. Biochem Biophys Res Commun 2010, 397:214-219.
    • (2010) Biochem Biophys Res Commun , vol.397 , pp. 214-219
    • Shibata, A.1    Nakagawa, K.2    Sookwong, P.3    Tsuduki, T.4    Asai, A.5    Miyazawa, T.6
  • 14
    • 34548058897 scopus 로고    scopus 로고
    • In vivo angiogenesis is suppressed by unsaturated vitamin E, tocotrienol
    • Nakagawa K., Shibata A., Yamashita S., Tsuzuki T., Kariya J., Oikawa S., et al. In vivo angiogenesis is suppressed by unsaturated vitamin E, tocotrienol. J Nutr 2007, 137:1938-1943.
    • (2007) J Nutr , vol.137 , pp. 1938-1943
    • Nakagawa, K.1    Shibata, A.2    Yamashita, S.3    Tsuzuki, T.4    Kariya, J.5    Oikawa, S.6
  • 15
    • 0029803056 scopus 로고    scopus 로고
    • A combined assay of cell viability and in vitro cytotoxicity with a highly water-soluble tetrazolium salt, neutral red and crystal violet
    • Ishiyama M., Tominaga H., Shiga M., Sasamoto K., Ohkura Y., Ueno K. A combined assay of cell viability and in vitro cytotoxicity with a highly water-soluble tetrazolium salt, neutral red and crystal violet. Biol Pharm Bull 1996, 19:1518-1520.
    • (1996) Biol Pharm Bull , vol.19 , pp. 1518-1520
    • Ishiyama, M.1    Tominaga, H.2    Shiga, M.3    Sasamoto, K.4    Ohkura, Y.5    Ueno, K.6
  • 18
    • 0037699954 scopus 로고    scopus 로고
    • The biology of VEGF and its receptors
    • Ferrara N., Gerber H.P., LeCouter J. The biology of VEGF and its receptors. Nat Med 2003, 9:669-676.
    • (2003) Nat Med , vol.9 , pp. 669-676
    • Ferrara, N.1    Gerber, H.P.2    LeCouter, J.3
  • 19
    • 47049121032 scopus 로고    scopus 로고
    • Vitamin E and cancer: an insight into the anticancer activities of vitamin E isomers and analogs
    • Constantinou C., Papas A., Constantinou A.I. Vitamin E and cancer: an insight into the anticancer activities of vitamin E isomers and analogs. Int J Cancer 2008, 123:739-752.
    • (2008) Int J Cancer , vol.123 , pp. 739-752
    • Constantinou, C.1    Papas, A.2    Constantinou, A.I.3
  • 20
    • 84888136254 scopus 로고    scopus 로고
    • Different tocopherol isoforms vary in capacity to scavenge free radicals, prevent inflammatory response, and induce apoptosis in both adult- and fetal-derived intestinal epithelial cells
    • Elisia I., Kitts D.D. Different tocopherol isoforms vary in capacity to scavenge free radicals, prevent inflammatory response, and induce apoptosis in both adult- and fetal-derived intestinal epithelial cells. Biofactors 2013, 39:663-671.
    • (2013) Biofactors , vol.39 , pp. 663-671
    • Elisia, I.1    Kitts, D.D.2
  • 21
    • 0033513497 scopus 로고    scopus 로고
    • Targeting vascular endothelial growth factor (VEGF) for anticancer therapy, by anti-VEGF neutralizing monoclonal antibodies and VEGF receptor tyrosine-kinase inhibitors
    • Schlaeppi J.M., Wood J.M. Targeting vascular endothelial growth factor (VEGF) for anticancer therapy, by anti-VEGF neutralizing monoclonal antibodies and VEGF receptor tyrosine-kinase inhibitors. Cancer Metastasis Rev 1999, 18:473-481.
    • (1999) Cancer Metastasis Rev , vol.18 , pp. 473-481
    • Schlaeppi, J.M.1    Wood, J.M.2
  • 23
    • 67650179212 scopus 로고    scopus 로고
    • 7-Ketocholesterol incorporation into sphingolipid/cholesterol-enriched (lipid raft) domains is impaired by vitamin E: a specific role for α-tocopherol with consequences on cell death
    • Royer M.C., Lemaire-Ewing S., Desrumaux C., Monier S., Pais de Barros J.P., Athias A., et al. 7-Ketocholesterol incorporation into sphingolipid/cholesterol-enriched (lipid raft) domains is impaired by vitamin E: a specific role for α-tocopherol with consequences on cell death. J Biol Chem 2009, 284:15826-15834.
    • (2009) J Biol Chem , vol.284 , pp. 15826-15834
    • Royer, M.C.1    Lemaire-Ewing, S.2    Desrumaux, C.3    Monier, S.4    Pais de Barros, J.P.5    Athias, A.6
  • 24
    • 84863261022 scopus 로고    scopus 로고
    • Signaling regulation of fetoplacental angiogenesis
    • Wang K., Zheng J. Signaling regulation of fetoplacental angiogenesis. J Endocrinol 2012, 212:243-255.
    • (2012) J Endocrinol , vol.212 , pp. 243-255
    • Wang, K.1    Zheng, J.2
  • 25
    • 77957909450 scopus 로고    scopus 로고
    • Tocotrienols, the vitamin E of the 21st century: its potential against cancer and other chronic diseases
    • Aggarwal B.B., Sundaram C., Prasad S., Kannappan R. Tocotrienols, the vitamin E of the 21st century: its potential against cancer and other chronic diseases. Biochem Pharmacol 2010, 80:1613-1631.
    • (2010) Biochem Pharmacol , vol.80 , pp. 1613-1631
    • Aggarwal, B.B.1    Sundaram, C.2    Prasad, S.3    Kannappan, R.4
  • 26
    • 0030064856 scopus 로고    scopus 로고
    • Dietary α-tocopherol attenuates the impact of γ-tocotrienol on hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in chickens
    • Qureshi A.A., Pearce B.C., Nor R.M., Gapor A., Peterson D.M., Elson C.E. Dietary α-tocopherol attenuates the impact of γ-tocotrienol on hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in chickens. J Nutr 1996, 126:389-394.
    • (1996) J Nutr , vol.126 , pp. 389-394
    • Qureshi, A.A.1    Pearce, B.C.2    Nor, R.M.3    Gapor, A.4    Peterson, D.M.5    Elson, C.E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.