Conversion of substrate analogs suggests a michael cyclization in iridoid biosynthesis

Chemistry and Biology

Volumn 21, Issue 11, 2014, Pages 1452-1456

  Lindner, Stephanie ^a,b   Geu Flores, Fernando ^b   Bräse, Stefan ^b,c   Sherden, Nathaniel H ^a   O'Connor, Sarah E ^a  

^a JOHN INNES CENTRE   (United Kingdom)

^b KARLSRUHE INSTITUTE OF TECHNOLOGY   (Germany)

^c KARLSRUHE INSTITUTE OF TECHNOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

IRIDOID; IRIDOID SYNTHASE; SYNTHETASE; UNCLASSIFIED DRUG; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; TERPENE; TRANSFERASE;

ACETALIZATION; ARTICLE; CHEMICAL STRUCTURE; CYCLIZATION; DIELS ALDER REACTION; ENZYMATIC ASSAY; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME MECHANISM; ENZYME STRUCTURE; ENZYME SUBSTRATE; ENZYME SYNTHESIS; HYDROGEN BOND; MICHAEL ADDITION; NUCLEAR OVERHAUSER EFFECT; REACTION ANALYSIS; STEREOCHEMISTRY; BIOCATALYSIS; CHEMISTRY; ENZYME SPECIFICITY; KINETICS; METABOLISM;

ALKYL AND ARYL TRANSFERASES; BIOCATALYSIS; CYCLIZATION; IRIDOIDS; KINETICS; NADP; SUBSTRATE SPECIFICITY; TERPENES;

EID: 84911903392     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2014.09.010     Document Type: Article

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