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Volumn 35, Issue 4, 2015, Pages 589-595

Role of osteopontin in rheumatoid arthritis

Author keywords

Integrins; Osteopontin; Pathogenesis; Rheumatoid arthritis

Indexed keywords

AUTOANTIGEN; CYTOKINE; NEUTRALIZING ANTIBODY; OSTEOPONTIN; SMALL INTERFERING RNA;

EID: 84925241070     PISSN: 01728172     EISSN: 1437160X     Source Type: Journal    
DOI: 10.1007/s00296-014-3122-z     Document Type: Review
Times cited : (30)

References (68)
  • 1
    • 0023179033 scopus 로고
    • Long-term outcome of treating rheumatoid arthritis: results after 20 years
    • COI: 1:STN:280:DyaL2s3gtVCktA%3D%3D, PID: 2883443
    • Scott DL, Symmons DP, Coulton BL, Popert AJ (1987) Long-term outcome of treating rheumatoid arthritis: results after 20 years. Lancet 1:1108–1111
    • (1987) Lancet , vol.1 , pp. 1108-1111
    • Scott, D.L.1    Symmons, D.P.2    Coulton, B.L.3    Popert, A.J.4
  • 3
    • 77957196913 scopus 로고    scopus 로고
    • Rheumatoid arthritis
    • PID: 20870100
    • Scott DL, Wolfe F, Huizinga TW (2010) Rheumatoid arthritis. Lancet 376:1094–1108
    • (2010) Lancet , vol.376 , pp. 1094-1108
    • Scott, D.L.1    Wolfe, F.2    Huizinga, T.W.3
  • 4
    • 34249720998 scopus 로고    scopus 로고
    • Cytokines in the pathogenesis of rheumatoid arthritis
    • COI: 1:CAS:528:DC%2BD2sXls1Kgt74%3D, PID: 17525752
    • McInnes IB, Schett G (2007) Cytokines in the pathogenesis of rheumatoid arthritis. Nat Rev Immunol 7:429–442
    • (2007) Nat Rev Immunol , vol.7 , pp. 429-442
    • McInnes, I.B.1    Schett, G.2
  • 5
    • 40549108688 scopus 로고    scopus 로고
    • Cells of the synovium in rheumatoid arthritis. Macrophages
    • PID: 18177511
    • Kinne RW, Stuhlmuller B, Burmester GR (2007) Cells of the synovium in rheumatoid arthritis. Macrophages. Arthritis Res Ther 9:224
    • (2007) Arthritis Res Ther , vol.9 , pp. 224
    • Kinne, R.W.1    Stuhlmuller, B.2    Burmester, G.R.3
  • 6
    • 0032981308 scopus 로고    scopus 로고
    • Pathogenesis of joint damage in rheumatoid arthritis
    • COI: 1:STN:280:DyaK1M7ovVGktw%3D%3D, PID: 10090189
    • Bresnihan B (1999) Pathogenesis of joint damage in rheumatoid arthritis. J Rheumatol 26:717–719
    • (1999) J Rheumatol , vol.26 , pp. 717-719
    • Bresnihan, B.1
  • 7
    • 0342578133 scopus 로고    scopus 로고
    • Mononuclear phagocytes and rheumatoid synovitis. Mastermind or workhorse in arthritis?
    • COI: 1:STN:280:DyaK2s7mtFegug%3D%3D, PID: 9008595
    • Burmester GR, Stuhlmuller B, Keyszer G, Kinne RW (1997) Mononuclear phagocytes and rheumatoid synovitis. Mastermind or workhorse in arthritis? Arthritis Rheum 40:5–18
    • (1997) Arthritis Rheum , vol.40 , pp. 5-18
    • Burmester, G.R.1    Stuhlmuller, B.2    Keyszer, G.3    Kinne, R.W.4
  • 9
    • 73249125200 scopus 로고    scopus 로고
    • Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis
    • COI: 1:CAS:528:DC%2BC3cXjslaqsr4%3D, PID: 20193003
    • Bartok B, Firestein GS (2010) Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis. Immunol Rev 233:233–255
    • (2010) Immunol Rev , vol.233 , pp. 233-255
    • Bartok, B.1    Firestein, G.S.2
  • 10
    • 47249086030 scopus 로고    scopus 로고
    • The role and therapeutic implications of fibroblast-like synoviocytes in inflammation and cartilage erosion in rheumatoid arthritis
    • COI: 1:CAS:528:DC%2BD1cXptlGlsbo%3D, PID: 18613841
    • Noss EH, Brenner MB (2008) The role and therapeutic implications of fibroblast-like synoviocytes in inflammation and cartilage erosion in rheumatoid arthritis. Immunol Rev 223:252–270
    • (2008) Immunol Rev , vol.223 , pp. 252-270
    • Noss, E.H.1    Brenner, M.B.2
  • 11
    • 84871768044 scopus 로고    scopus 로고
    • T cells out of control—impaired immune regulation in the inflamed joint
    • COI: 1:CAS:528:DC%2BC38XhvFSitbvM, PID: 23390638
    • Wehrens EJ, Prakken BJ, van Wijk F (2013) T cells out of control—impaired immune regulation in the inflamed joint. Nat Rev Rheumatol 9:34–42
    • (2013) Nat Rev Rheumatol , vol.9 , pp. 34-42
    • Wehrens, E.J.1    Prakken, B.J.2    van Wijk, F.3
  • 12
    • 78650784468 scopus 로고    scopus 로고
    • V-region gene analysis of locally defined synovial B and plasma cells reveals selected B cell expansion and accumulation of plasma cell clones in rheumatoid arthritis
    • COI: 1:CAS:528:DC%2BC3MXitVeqsLY%3D, PID: 20882667
    • Scheel T, Gursche A, Zacher J, Haupl T, Berek C (2011) V-region gene analysis of locally defined synovial B and plasma cells reveals selected B cell expansion and accumulation of plasma cell clones in rheumatoid arthritis. Arthritis Rheum 63:63–72
    • (2011) Arthritis Rheum , vol.63 , pp. 63-72
    • Scheel, T.1    Gursche, A.2    Zacher, J.3    Haupl, T.4    Berek, C.5
  • 13
    • 36048930464 scopus 로고    scopus 로고
    • Cells of the synovium in rheumatoid arthritis. B cells
    • PID: 17349064
    • Mauri C, Ehrenstein MR (2007) Cells of the synovium in rheumatoid arthritis. B cells. Arthritis Res Ther 9:205
    • (2007) Arthritis Res Ther , vol.9 , pp. 205
    • Mauri, C.1    Ehrenstein, M.R.2
  • 14
    • 0043245084 scopus 로고    scopus 로고
    • Osteopontin: a bridge between bone and the immune system
    • COI: 1:CAS:528:DC%2BD3sXlslWlt78%3D, PID: 12865402
    • Gravallese EM (2003) Osteopontin: a bridge between bone and the immune system. J Clin Invest 112:147–149
    • (2003) J Clin Invest , vol.112 , pp. 147-149
    • Gravallese, E.M.1
  • 15
    • 84872301400 scopus 로고    scopus 로고
    • The effect of hyaluronic acid on osteopontin and CD44 mRNA of fibroblast-like synoviocytes in patients with osteoarthritis of the knee
    • PID: 22218639
    • Zhang FJ, Gao SG, Cheng L, Tian J, Xu WS, Luo W, Song Y, Yang Y, Lei GH (2013) The effect of hyaluronic acid on osteopontin and CD44 mRNA of fibroblast-like synoviocytes in patients with osteoarthritis of the knee. Rheumatol Int 33:79–83
    • (2013) Rheumatol Int , vol.33 , pp. 79-83
    • Zhang, F.J.1    Gao, S.G.2    Cheng, L.3    Tian, J.4    Xu, W.S.5    Luo, W.6    Song, Y.7    Yang, Y.8    Lei, G.H.9
  • 16
    • 0032432558 scopus 로고    scopus 로고
    • Osteopontin expression and function: role in bone remodeling
    • PID: 9893260
    • Denhardt DT, Noda M (1998) Osteopontin expression and function: role in bone remodeling. J Cell Biochem Suppl 30–31:92–102
    • (1998) J Cell Biochem Suppl , vol.30-31 , pp. 92-102
    • Denhardt, D.T.1    Noda, M.2
  • 17
    • 0025947139 scopus 로고
    • Polyclonal B cell activation by the Eta-1 cytokine and the development of systemic autoimmune disease
    • COI: 1:CAS:528:DyaK38XltVyk, PID: 1918998
    • Lampe MA, Patarca R, Iregui MV, Cantor H (1991) Polyclonal B cell activation by the Eta-1 cytokine and the development of systemic autoimmune disease. J Immunol 147:2902–2906
    • (1991) J Immunol , vol.147 , pp. 2902-2906
    • Lampe, M.A.1    Patarca, R.2    Iregui, M.V.3    Cantor, H.4
  • 18
    • 0024337752 scopus 로고
    • Structural and functional studies of the early T lymphocyte activation 1 (Eta-1) gene. Definition of a novel T cell-dependent response associated with genetic resistance to bacterial infection
    • COI: 1:CAS:528:DyaK3cXhvFartrw%3D, PID: 2787378
    • Patarca R, Freeman GJ, Singh RP et al (1989) Structural and functional studies of the early T lymphocyte activation 1 (Eta-1) gene. Definition of a novel T cell-dependent response associated with genetic resistance to bacterial infection. J Exp Med 170:145–161
    • (1989) J Exp Med , vol.170 , pp. 145-161
    • Patarca, R.1    Freeman, G.J.2    Singh, R.P.3
  • 19
    • 0024994985 scopus 로고
    • cDNA cloning, mRNA distribution and heterogeneity, chromosomal location, and RFLP analysis of human osteopontin (OPN)
    • COI: 1:CAS:528:DyaK3MXjs1ymuw%3D%3D, PID: 1974876
    • Young MF, Kerr JM, Termine JD, Wewer UM, Wang MG, McBride OW, Fisher LW (1990) cDNA cloning, mRNA distribution and heterogeneity, chromosomal location, and RFLP analysis of human osteopontin (OPN). Genomics 7:491–502
    • (1990) Genomics , vol.7 , pp. 491-502
    • Young, M.F.1    Kerr, J.M.2    Termine, J.D.3    Wewer, U.M.4    Wang, M.G.5    McBride, O.W.6    Fisher, L.W.7
  • 20
    • 0027131418 scopus 로고
    • Osteopontin: a protein with diverse functions
    • COI: 1:CAS:528:DyaK2cXkvVaiug%3D%3D, PID: 8262332
    • Denhardt DT, Guo X (1993) Osteopontin: a protein with diverse functions. FASEB J 7:1475–1482
    • (1993) FASEB J , vol.7 , pp. 1475-1482
    • Denhardt, D.T.1    Guo, X.2
  • 21
    • 0034455957 scopus 로고    scopus 로고
    • Osteopontin: a key cytokine in cell-mediated and granulomatous inflammation
    • PID: 11298186
    • O’Regan A, Berman JS (2000) Osteopontin: a key cytokine in cell-mediated and granulomatous inflammation. Int J Exp Pathol 81:373–390
    • (2000) Int J Exp Pathol , vol.81 , pp. 373-390
    • O’Regan, A.1    Berman, J.S.2
  • 22
    • 0035966343 scopus 로고    scopus 로고
    • The metastasis gene osteopontin: a candidate target for cancer therapy
    • COI: 1:CAS:528:DC%2BD38XhsFahs74%3D, PID: 11825687
    • Weber GF (2001) The metastasis gene osteopontin: a candidate target for cancer therapy. Biochim Biophys Acta 1552:61–85
    • (2001) Biochim Biophys Acta , vol.1552 , pp. 61-85
    • Weber, G.F.1
  • 23
    • 0029942138 scopus 로고    scopus 로고
    • Low-molecular-weight variants of osteopontin generated by serine proteinases in urine of patients with kidney stones
    • COI: 1:CAS:528:DyaK28XjsVSqsrc%3D, PID: 8761944
    • Bautista DS, Denstedt J, Chambers AF, Harris JF (1996) Low-molecular-weight variants of osteopontin generated by serine proteinases in urine of patients with kidney stones. J Cell Biochem 61:402–409
    • (1996) J Cell Biochem , vol.61 , pp. 402-409
    • Bautista, D.S.1    Denstedt, J.2    Chambers, A.F.3    Harris, J.F.4
  • 24
    • 0033579511 scopus 로고    scopus 로고
    • The integrin alpha(9)beta(1) binds to a novel recognition sequence (SVVYGLR) in the thrombin-cleaved amino-terminal fragment of osteopontin
    • COI: 1:CAS:528:DC%2BD3cXitF2g, PID: 10593924
    • Yokosaki Y, Matsuura N, Sasaki T et al (1999) The integrin alpha(9)beta(1) binds to a novel recognition sequence (SVVYGLR) in the thrombin-cleaved amino-terminal fragment of osteopontin. J Biol Chem 274:36328–36334
    • (1999) J Biol Chem , vol.274 , pp. 36328-36334
    • Yokosaki, Y.1    Matsuura, N.2    Sasaki, T.3
  • 25
    • 21444449356 scopus 로고    scopus 로고
    • Prevention of the cryptic epitope SLAYGLR within osteopontin does not influence susceptibility to Candida albicans infection
    • COI: 1:CAS:528:DC%2BD2MXlvFSlt7w%3D, PID: 15980398
    • Sato I, Yamamoto N, Yamazaki H, Hashimoto S, Hino M, Sakai F, Fujie A (2005) Prevention of the cryptic epitope SLAYGLR within osteopontin does not influence susceptibility to Candida albicans infection. Antimicrob Agents Chemother 49:3053–3055
    • (2005) Antimicrob Agents Chemother , vol.49 , pp. 3053-3055
    • Sato, I.1    Yamamoto, N.2    Yamazaki, H.3    Hashimoto, S.4    Hino, M.5    Sakai, F.6    Fujie, A.7
  • 26
    • 0035839024 scopus 로고    scopus 로고
    • Structural elements of the osteopontin SVVYGLR motif important for the interaction with alpha(4) integrins
    • COI: 1:CAS:528:DC%2BD3MXmtFWisbg%3D, PID: 11513858
    • Green PM, Ludbrook SB, Miller DD, Horgan CM, Barry ST (2001) Structural elements of the osteopontin SVVYGLR motif important for the interaction with alpha(4) integrins. FEBS Lett 503:75–79
    • (2001) FEBS Lett , vol.503 , pp. 75-79
    • Green, P.M.1    Ludbrook, S.B.2    Miller, D.D.3    Horgan, C.M.4    Barry, S.T.5
  • 27
    • 70349773144 scopus 로고    scopus 로고
    • Thrombin-activatable carboxypeptidase B cleavage of osteopontin regulates neutrophil survival and synoviocyte binding in rheumatoid arthritis
    • COI: 1:CAS:528:DC%2BD1MXhsFOmtbnF, PID: 19790060
    • Sharif SA, Du X, Myles T et al (2009) Thrombin-activatable carboxypeptidase B cleavage of osteopontin regulates neutrophil survival and synoviocyte binding in rheumatoid arthritis. Arthritis Rheum 60:2902–2912
    • (2009) Arthritis Rheum , vol.60 , pp. 2902-2912
    • Sharif, S.A.1    Du, X.2    Myles, T.3
  • 28
    • 0345803939 scopus 로고    scopus 로고
    • Thrombin activatable fibrinolysis inhibitor, a potential regulator of vascular inflammation
    • COI: 1:CAS:528:DC%2BD3sXpslOhs7c%3D, PID: 14525995
    • Myles T, Nishimura T, Yun TH et al (2003) Thrombin activatable fibrinolysis inhibitor, a potential regulator of vascular inflammation. J Biol Chem 278:51059–51067
    • (2003) J Biol Chem , vol.278 , pp. 51059-51067
    • Myles, T.1    Nishimura, T.2    Yun, T.H.3
  • 29
    • 0034238108 scopus 로고    scopus 로고
    • Analysis of the alpha4beta1 integrin–osteopontin interaction
    • COI: 1:CAS:528:DC%2BD3cXkvVWrtr8%3D, PID: 10896785
    • Barry ST, Ludbrook SB, Murrison E, Horgan CM (2000) Analysis of the alpha4beta1 integrin–osteopontin interaction. Exp Cell Res 258:342–351
    • (2000) Exp Cell Res , vol.258 , pp. 342-351
    • Barry, S.T.1    Ludbrook, S.B.2    Murrison, E.3    Horgan, C.M.4
  • 30
    • 0034719167 scopus 로고    scopus 로고
    • A regulated interaction between alpha5beta1 integrin and osteopontin
    • COI: 1:CAS:528:DC%2BD3cXhtVKmsLg%3D, PID: 10673366
    • Barry ST, Ludbrook SB, Murrison E, Horgan CM (2000) A regulated interaction between alpha5beta1 integrin and osteopontin. Biochem Biophys Res Commun 267:764–769
    • (2000) Biochem Biophys Res Commun , vol.267 , pp. 764-769
    • Barry, S.T.1    Ludbrook, S.B.2    Murrison, E.3    Horgan, C.M.4
  • 31
    • 0026334978 scopus 로고
    • Glioblastoma expression of vitronectin and the alpha v beta 3 integrin. Adhesion mechanism for transformed glial cells
    • COI: 1:CAS:528:DyaK38Xls1Crsw%3D%3D, PID: 1721625
    • Gladson CL, Cheresh DA (1991) Glioblastoma expression of vitronectin and the alpha v beta 3 integrin. Adhesion mechanism for transformed glial cells. J Clin Invest 88:1924–1932
    • (1991) J Clin Invest , vol.88 , pp. 1924-1932
    • Gladson, C.L.1    Cheresh, D.A.2
  • 32
    • 38549097166 scopus 로고    scopus 로고
    • Osteopontin: regulation in tumor metastasis
    • COI: 1:CAS:528:DC%2BD1cXhtV2gurg%3D, PID: 18049863
    • Wai PY, Kuo PC (2008) Osteopontin: regulation in tumor metastasis. Cancer Metastasis Rev 27:103–118
    • (2008) Cancer Metastasis Rev , vol.27 , pp. 103-118
    • Wai, P.Y.1    Kuo, P.C.2
  • 33
    • 0028853560 scopus 로고
    • A biochemical characterization of the binding of osteopontin to integrins alpha v beta 1 and alpha v beta 5
    • COI: 1:CAS:528:DyaK2MXpt1eju7g%3D, PID: 7592829
    • Hu DD, Lin EC, Kovach NL, Hoyer JR, Smith JW (1995) A biochemical characterization of the binding of osteopontin to integrins alpha v beta 1 and alpha v beta 5. J Biol Chem 270:26232–26238
    • (1995) J Biol Chem , vol.270 , pp. 26232-26238
    • Hu, D.D.1    Lin, E.C.2    Kovach, N.L.3    Hoyer, J.R.4    Smith, J.W.5
  • 34
    • 0031802697 scopus 로고    scopus 로고
    • Osteopontin is a ligand for the alpha4beta1 integrin
    • COI: 1:CAS:528:DyaK1cXjslWru70%3D, PID: 9547293
    • Bayless KJ, Meininger GA, Scholtz JM, Davis GE (1998) Osteopontin is a ligand for the alpha4beta1 integrin. J Cell Sci 111(Pt 9):1165–1174
    • (1998) J Cell Sci , vol.111 , pp. 1165-1174
    • Bayless, K.J.1    Meininger, G.A.2    Scholtz, J.M.3    Davis, G.E.4
  • 35
    • 0031813775 scopus 로고    scopus 로고
    • Identification of osteopontin as a novel ligand for the integrin alpha8 beta1 and potential roles for this integrin–ligand interaction in kidney morphogenesis
    • COI: 1:CAS:528:DyaK1cXjvVehsL4%3D, PID: 9614184
    • Denda S, Reichardt LF, Muller U (1998) Identification of osteopontin as a novel ligand for the integrin alpha8 beta1 and potential roles for this integrin–ligand interaction in kidney morphogenesis. Mol Biol Cell 9:1425–1435
    • (1998) Mol Biol Cell , vol.9 , pp. 1425-1435
    • Denda, S.1    Reichardt, L.F.2    Muller, U.3
  • 36
    • 0029120722 scopus 로고
    • Osteopontin: a ligand for the alpha v beta 3 integrin of the osteoclast clear zone in osteopetrotic (ia/ia) rats
    • COI: 1:CAS:528:DyaK2MXovVSit7Y%3D, PID: 7540376
    • Hultenby K, Reinholt FP, Heinegard D, Andersson G, Marks SJ (1995) Osteopontin: a ligand for the alpha v beta 3 integrin of the osteoclast clear zone in osteopetrotic (ia/ia) rats. Ann NY Acad Sci 760:315–318
    • (1995) Ann NY Acad Sci , vol.760 , pp. 315-318
    • Hultenby, K.1    Reinholt, F.P.2    Heinegard, D.3    Andersson, G.4    Marks, S.J.5
  • 37
    • 0034813288 scopus 로고    scopus 로고
    • Endometrial osteopontin, a ligand of beta3-integrin, is maximally expressed around the time of the “implantation window
    • von Wolff M, Strowitzki T, Becker V, Zepf C, Tabibzadeh S, Thaler CJ (2001) Endometrial osteopontin, a ligand of beta3-integrin, is maximally expressed around the time of the “implantation window”. Fertil Steril 76:775–781
    • (2001) Fertil Steril , vol.76 , pp. 775-781
    • von Wolff, M.1    Strowitzki, T.2    Becker, V.3    Zepf, C.4    Tabibzadeh, S.5    Thaler, C.J.6
  • 38
    • 0030064334 scopus 로고    scopus 로고
    • Receptor–ligand interaction between CD44 and osteopontin (Eta-1)
    • COI: 1:CAS:528:DyaK28XmvFyrtA%3D%3D, PID: 8560266
    • Weber GF, Ashkar S, Glimcher MJ, Cantor H (1996) Receptor–ligand interaction between CD44 and osteopontin (Eta-1). Science 271:509–512
    • (1996) Science , vol.271 , pp. 509-512
    • Weber, G.F.1    Ashkar, S.2    Glimcher, M.J.3    Cantor, H.4
  • 39
    • 34547102777 scopus 로고    scopus 로고
    • Cell type-specific post-translational modifications of mouse osteopontin are associated with different adhesive properties
    • COI: 1:CAS:528:DC%2BD2sXntFWkurs%3D, PID: 17500062
    • Christensen B, Kazanecki CC, Petersen TE, Rittling SR, Denhardt DT, Sorensen ES (2007) Cell type-specific post-translational modifications of mouse osteopontin are associated with different adhesive properties. J Biol Chem 282:19463–19472
    • (2007) J Biol Chem , vol.282 , pp. 19463-19472
    • Christensen, B.1    Kazanecki, C.C.2    Petersen, T.E.3    Rittling, S.R.4    Denhardt, D.T.5    Sorensen, E.S.6
  • 41
    • 6344258588 scopus 로고    scopus 로고
    • The role of osteopontin in tumor metastasis
    • COI: 1:CAS:528:DC%2BD2cXovVyru7c%3D, PID: 15501463
    • Wai PY, Kuo PC (2004) The role of osteopontin in tumor metastasis. J Surg Res 121:228–241
    • (2004) J Surg Res , vol.121 , pp. 228-241
    • Wai, P.Y.1    Kuo, P.C.2
  • 42
    • 0033923116 scopus 로고    scopus 로고
    • Expression of osteopontin messenger RNA and protein in rheumatoid arthritis: effects of osteopontin on the release of collagenase 1 from articular chondrocytes and synovial fibroblasts
    • COI: 1:CAS:528:DC%2BD3cXlsV2mtro%3D, PID: 10902765
    • Petrow PK, Hummel KM, Schedel J et al (2000) Expression of osteopontin messenger RNA and protein in rheumatoid arthritis: effects of osteopontin on the release of collagenase 1 from articular chondrocytes and synovial fibroblasts. Arthritis Rheum 43:1597–1605
    • (2000) Arthritis Rheum , vol.43 , pp. 1597-1605
    • Petrow, P.K.1    Hummel, K.M.2    Schedel, J.3
  • 43
    • 0036791904 scopus 로고    scopus 로고
    • Enhanced local production of osteopontin in rheumatoid joints
    • COI: 1:CAS:528:DC%2BD38XosVGisbY%3D, PID: 12375312
    • Ohshima S, Yamaguchi N, Nishioka K et al (2002) Enhanced local production of osteopontin in rheumatoid joints. J Rheumatol 29:2061–2067
    • (2002) J Rheumatol , vol.29 , pp. 2061-2067
    • Ohshima, S.1    Yamaguchi, N.2    Nishioka, K.3
  • 44
    • 20144389023 scopus 로고    scopus 로고
    • Role of osteopontin in amplification and perpetuation of rheumatoid synovitis
    • COI: 1:CAS:528:DC%2BD2MXjtFyltL0%3D, PID: 15761492
    • Xu G, Nie H, Li N, Zheng W, Zhang D, Feng G, Ni L, Xu R, Hong J, Zhang JZ (2005) Role of osteopontin in amplification and perpetuation of rheumatoid synovitis. J Clin Invest 115:1060–1067
    • (2005) J Clin Invest , vol.115 , pp. 1060-1067
    • Xu, G.1    Nie, H.2    Li, N.3    Zheng, W.4    Zhang, D.5    Feng, G.6    Ni, L.7    Xu, R.8    Hong, J.9    Zhang, J.Z.10
  • 45
    • 67650079429 scopus 로고    scopus 로고
    • Role of osteopontin in induction of monocyte chemoattractant protein 1 and macrophage inflammatory protein 1beta through the NF-kappaB and MAPK pathways in rheumatoid arthritis
    • COI: 1:CAS:528:DC%2BD1MXptlKktbY%3D, PID: 19565503
    • Zheng W, Li R, Pan H, He D, Xu R, Guo TB, Guo Y, Zhang JZ (2009) Role of osteopontin in induction of monocyte chemoattractant protein 1 and macrophage inflammatory protein 1beta through the NF-kappaB and MAPK pathways in rheumatoid arthritis. Arthritis Rheum 60:1957–1965
    • (2009) Arthritis Rheum , vol.60 , pp. 1957-1965
    • Zheng, W.1    Li, R.2    Pan, H.3    He, D.4    Xu, R.5    Guo, T.B.6    Guo, Y.7    Zhang, J.Z.8
  • 46
    • 77957689334 scopus 로고    scopus 로고
    • Role of osteopontin in synovial Th17 differentiation in rheumatoid arthritis
    • COI: 1:CAS:528:DC%2BC3cXhsVSqtrrE, PID: 20533542
    • Chen G, Zhang X, Li R, Fang L, Niu X, Zheng Y, He D, Xu R, Zhang JZ (2010) Role of osteopontin in synovial Th17 differentiation in rheumatoid arthritis. Arthritis Rheum 62:2900–2908
    • (2010) Arthritis Rheum , vol.62 , pp. 2900-2908
    • Chen, G.1    Zhang, X.2    Li, R.3    Fang, L.4    Niu, X.5    Zheng, Y.6    He, D.7    Xu, R.8    Zhang, J.Z.9
  • 47
    • 0036229093 scopus 로고    scopus 로고
    • Expression of osteopontin at sites of bone erosion in a murine experimental arthritis model of collagen-induced arthritis: possible involvement of osteopontin in bone destruction in arthritis
    • COI: 1:CAS:528:DC%2BD38Xjs12ltLk%3D, PID: 11953989
    • Ohshima S, Kobayashi H, Yamaguchi N et al (2002) Expression of osteopontin at sites of bone erosion in a murine experimental arthritis model of collagen-induced arthritis: possible involvement of osteopontin in bone destruction in arthritis. Arthritis Rheum 46:1094–1101
    • (2002) Arthritis Rheum , vol.46 , pp. 1094-1101
    • Ohshima, S.1    Kobayashi, H.2    Yamaguchi, N.3
  • 48
    • 84893699415 scopus 로고    scopus 로고
    • Plasma osteopontin is correlated with bone resorption markers in rheumatoid arthritis patients
    • COI: 1:CAS:528:DC%2BC2cXhs1Oktb8%3D, PID: 24472267
    • Iwadate H, Kobayashi H, Kanno T et al (2014) Plasma osteopontin is correlated with bone resorption markers in rheumatoid arthritis patients. Int J Rheum Dis 17:50–56
    • (2014) Int J Rheum Dis , vol.17 , pp. 50-56
    • Iwadate, H.1    Kobayashi, H.2    Kanno, T.3
  • 49
    • 84896488601 scopus 로고    scopus 로고
    • Serum level of osteopontin as an inflammatory marker does not indicate disease activity or responsiveness to therapeutic treatments in patients with rheumatoid arthritis
    • PID: 23995733
    • Ji HI, Lee SH, Song R et al (2014) Serum level of osteopontin as an inflammatory marker does not indicate disease activity or responsiveness to therapeutic treatments in patients with rheumatoid arthritis. Clin Rheumatol 33:397–402
    • (2014) Clin Rheumatol , vol.33 , pp. 397-402
    • Ji, H.I.1    Lee, S.H.2    Song, R.3
  • 50
    • 4544233664 scopus 로고    scopus 로고
    • Synovial expression of osteopontin correlates with angiogenesis in juvenile idiopathic arthritis
    • COI: 1:CAS:528:DC%2BD2cXntFagsL4%3D
    • Gattorno M, Gregorio A, Ferlito F et al (2004) Synovial expression of osteopontin correlates with angiogenesis in juvenile idiopathic arthritis. Rheumatology (Oxford) 43:1091–1096
    • (2004) Rheumatology (Oxford) , vol.43 , pp. 1091-1096
    • Gattorno, M.1    Gregorio, A.2    Ferlito, F.3
  • 51
    • 64849106673 scopus 로고    scopus 로고
    • Thrombin-cleaved osteopontin in synovial fluid of subjects with rheumatoid arthritis
    • COI: 1:CAS:528:DC%2BD1MXjt1Cmtr8%3D, PID: 19208558
    • Hasegawa M, Nakoshi Y, Iino T, Sudo A, Segawa T, Maeda M, Yoshida T, Uchida A (2009) Thrombin-cleaved osteopontin in synovial fluid of subjects with rheumatoid arthritis. J Rheumatol 36:240–245
    • (2009) J Rheumatol , vol.36 , pp. 240-245
    • Hasegawa, M.1    Nakoshi, Y.2    Iino, T.3    Sudo, A.4    Segawa, T.5    Maeda, M.6    Yoshida, T.7    Uchida, A.8
  • 52
    • 77950640465 scopus 로고    scopus 로고
    • Thrombin-cleaved osteopontin is increased in urine of patients with rheumatoid arthritis
    • COI: 1:CAS:528:DC%2BC3cXmtFCru74%3D, PID: 20156944
    • Shio K, Kobayashi H, Asano T et al (2010) Thrombin-cleaved osteopontin is increased in urine of patients with rheumatoid arthritis. J Rheumatol 37:704–710
    • (2010) J Rheumatol , vol.37 , pp. 704-710
    • Shio, K.1    Kobayashi, H.2    Asano, T.3
  • 53
    • 20144367221 scopus 로고    scopus 로고
    • Overexpression of osteopontin in rheumatoid synovial mononuclear cells is associated with joint inflammation, not with genetic polymorphism
    • COI: 1:CAS:528:DC%2BD2MXivVyns7w%3D, PID: 15742430
    • Xu G, Sun W, He D, Wang L, Zheng W, Nie H, Ni L, Zhang D, Li N, Zhang J (2005) Overexpression of osteopontin in rheumatoid synovial mononuclear cells is associated with joint inflammation, not with genetic polymorphism. J Rheumatol 32:410–416
    • (2005) J Rheumatol , vol.32 , pp. 410-416
    • Xu, G.1    Sun, W.2    He, D.3    Wang, L.4    Zheng, W.5    Nie, H.6    Ni, L.7    Zhang, D.8    Li, N.9    Zhang, J.10
  • 54
    • 33646265053 scopus 로고    scopus 로고
    • A polymorphic variant inside the osteopontin gene shows association with disease course in oligoarticular juvenile idiopathic arthritis
    • COI: 1:CAS:528:DC%2BD28XkvFyqurs%3D, PID: 16150788
    • Marciano R, Giacopelli F, Divizia MT et al (2006) A polymorphic variant inside the osteopontin gene shows association with disease course in oligoarticular juvenile idiopathic arthritis. Ann Rheum Dis 65:662–665
    • (2006) Ann Rheum Dis , vol.65 , pp. 662-665
    • Marciano, R.1    Giacopelli, F.2    Divizia, M.T.3
  • 55
    • 85027946337 scopus 로고    scopus 로고
    • Identification of secreted phosphoprotein 1 gene as a new rheumatoid arthritis susceptibility gene. Ann Rheum Dis
    • Gazal S, Sacre K, Allanore Y et al (2014) Identification of secreted phosphoprotein 1 gene as a new rheumatoid arthritis susceptibility gene. Ann Rheum Dis. doi:10.1136/annrheumdis-2013-204581
    • (2014) doi:10.1136/annrheumdis-2013-204581
    • Gazal, S.1    Sacre, K.2    Allanore, Y.3
  • 56
    • 73249151839 scopus 로고    scopus 로고
    • Specifically modified osteopontin in rheumatoid arthritis fibroblast-like synoviocytes supports interaction with B cells and enhances production of interleukin-6
    • COI: 1:CAS:528:DC%2BC3cXhtFKhtb7I, PID: 19950274
    • Take Y, Nakata K, Hashimoto J, Tsuboi H, Nishimoto N, Ochi T, Yoshikawa H (2009) Specifically modified osteopontin in rheumatoid arthritis fibroblast-like synoviocytes supports interaction with B cells and enhances production of interleukin-6. Arthritis Rheum 60:3591–3601
    • (2009) Arthritis Rheum , vol.60 , pp. 3591-3601
    • Take, Y.1    Nakata, K.2    Hashimoto, J.3    Tsuboi, H.4    Nishimoto, N.5    Ochi, T.6    Yoshikawa, H.7
  • 57
    • 84901698295 scopus 로고    scopus 로고
    • alpha9beta1 integrin acts as a critical intrinsic regulator of human rheumatoid arthritis
    • COI: 1:CAS:528:DC%2BC2cXjt1Srsro%3D
    • Asano T, Iwasaki N, Kon S, Kanayama M, Morimoto J, Minami A, Uede T (2014) alpha9beta1 integrin acts as a critical intrinsic regulator of human rheumatoid arthritis. Rheumatology (Oxford) 53:415–424
    • (2014) Rheumatology (Oxford) , vol.53 , pp. 415-424
    • Asano, T.1    Iwasaki, N.2    Kon, S.3    Kanayama, M.4    Morimoto, J.5    Minami, A.6    Uede, T.7
  • 58
    • 0037007098 scopus 로고    scopus 로고
    • Osteopontin deficiency protects joints against destruction in anti-type II collagen antibody-induced arthritis in mice
    • COI: 1:CAS:528:DC%2BD38XivFShurk%3D, PID: 11930008
    • Yumoto K, Ishijima M, Rittling SR et al (2002) Osteopontin deficiency protects joints against destruction in anti-type II collagen antibody-induced arthritis in mice. Proc Natl Acad Sci USA 99:4556–4561
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 4556-4561
    • Yumoto, K.1    Ishijima, M.2    Rittling, S.R.3
  • 59
    • 12144288292 scopus 로고    scopus 로고
    • Osteopontin as a positive regulator in the osteoclastogenesis of arthritis
    • COI: 1:CAS:528:DC%2BD2cXitFKgsbk%3D, PID: 15033472
    • Ishii T, Ohshima S, Ishida T et al (2004) Osteopontin as a positive regulator in the osteoclastogenesis of arthritis. Biochem Biophys Res Commun 316:809–815
    • (2004) Biochem Biophys Res Commun , vol.316 , pp. 809-815
    • Ishii, T.1    Ohshima, S.2    Ishida, T.3
  • 60
    • 85047690295 scopus 로고    scopus 로고
    • Essential role of the cryptic epitope SLAYGLR within osteopontin in a murine model of rheumatoid arthritis
    • COI: 1:CAS:528:DC%2BD3sXlslWlt7g%3D, PID: 12865407
    • Yamamoto N, Sakai F, Kon S et al (2003) Essential role of the cryptic epitope SLAYGLR within osteopontin in a murine model of rheumatoid arthritis. J Clin Invest 112:181–188
    • (2003) J Clin Invest , vol.112 , pp. 181-188
    • Yamamoto, N.1    Sakai, F.2    Kon, S.3
  • 61
    • 67649204689 scopus 로고    scopus 로고
    • Alpha9 integrin and its ligands constitute critical joint microenvironments for development of autoimmune arthritis
    • COI: 1:CAS:528:DC%2BD1MXmslCntbw%3D, PID: 19494327
    • Kanayama M, Kurotaki D, Morimoto J et al (2009) Alpha9 integrin and its ligands constitute critical joint microenvironments for development of autoimmune arthritis. J Immunol 182:8015–8025
    • (2009) J Immunol , vol.182 , pp. 8015-8025
    • Kanayama, M.1    Kurotaki, D.2    Morimoto, J.3
  • 62
    • 82755187678 scopus 로고    scopus 로고
    • alpha9beta1 integrin-mediated signaling serves as an intrinsic regulator of pathogenic Th17 cell generation
    • COI: 1:CAS:528:DC%2BC3MXhsV2hsLvO, PID: 22039306
    • Kanayama M, Morimoto J, Matsui Y et al (2011) alpha9beta1 integrin-mediated signaling serves as an intrinsic regulator of pathogenic Th17 cell generation. J Immunol 187:5851–5864
    • (2011) J Immunol , vol.187 , pp. 5851-5864
    • Kanayama, M.1    Morimoto, J.2    Matsui, Y.3
  • 63
    • 69249215187 scopus 로고    scopus 로고
    • Therapeutic silencing of an endogenous gene by siRNA cream in an arthritis model mouse
    • COI: 1:CAS:528:DC%2BD1MXmsVOqs7o%3D, PID: 19474812
    • Takanashi M, Oikawa K, Sudo K et al (2009) Therapeutic silencing of an endogenous gene by siRNA cream in an arthritis model mouse. Gene Ther 16:982–989
    • (2009) Gene Ther , vol.16 , pp. 982-989
    • Takanashi, M.1    Oikawa, K.2    Sudo, K.3
  • 64
    • 0034930681 scopus 로고    scopus 로고
    • Autoantibodies to osteopontin in patients with osteoarthritis and rheumatoid arthritis
    • COI: 1:STN:280:DC%2BD38%2Fit1Okuw%3D%3D, PID: 11469452
    • Sakata M, Tsuruha JI, Masuko-Hongo K et al (2001) Autoantibodies to osteopontin in patients with osteoarthritis and rheumatoid arthritis. J Rheumatol 28:1492–1495
    • (2001) J Rheumatol , vol.28 , pp. 1492-1495
    • Sakata, M.1    Tsuruha, J.I.2    Masuko-Hongo, K.3
  • 65
    • 47249145601 scopus 로고    scopus 로고
    • Treatment of collagen-induced arthritis with an anti-osteopontin monoclonal antibody through promotion of apoptosis of both murine and human activated T cells
    • COI: 1:CAS:528:DC%2BD1cXpt1Wku7o%3D, PID: 18576331
    • Fan K, Dai J, Wang H, Wei H et al (2008) Treatment of collagen-induced arthritis with an anti-osteopontin monoclonal antibody through promotion of apoptosis of both murine and human activated T cells. Arthritis Rheum 58:2041–2052
    • (2008) Arthritis Rheum , vol.58 , pp. 2041-2052
    • Fan, K.1    Dai, J.2    Wang, H.3    Wei, H.4
  • 66
    • 34548142961 scopus 로고    scopus 로고
    • Successful treatment of collagen-induced arthritis in non-human primates by chimeric anti-osteopontin antibody
    • COI: 1:CAS:528:DC%2BD2sXpvFKitL4%3D, PID: 17761350
    • Yamamoto N, Nakashima T, Torikai M, Naruse T, Morimoto J, Kon S, Sakai F, Uede T (2007) Successful treatment of collagen-induced arthritis in non-human primates by chimeric anti-osteopontin antibody. Int Immunopharmacol 7:1460–1470
    • (2007) Int Immunopharmacol , vol.7 , pp. 1460-1470
    • Yamamoto, N.1    Nakashima, T.2    Torikai, M.3    Naruse, T.4    Morimoto, J.5    Kon, S.6    Sakai, F.7    Uede, T.8
  • 67
    • 0036839554 scopus 로고    scopus 로고
    • Integrin alpha V beta 3 as a target for treatment of rheumatoid arthritis and related rheumatic diseases
    • Wilder RL (2002) Integrin alpha V beta 3 as a target for treatment of rheumatoid arthritis and related rheumatic diseases. Ann Rheum Dis 61(Suppl 2):i96–i99
    • (2002) Ann Rheum Dis , vol.61 , pp. 96-99
    • Wilder, R.L.1
  • 68
    • 84855358061 scopus 로고    scopus 로고
    • Safety, tolerability, pharmacokinetics, pharmacodynamics and efficacy of the monoclonal antibody ASK8007 blocking osteopontin in patients with rheumatoid arthritis: a randomised, placebo controlled, proof-of-concept study
    • COI: 1:CAS:528:DC%2BC38XisVSmt74%3D, PID: 21917822
    • Boumans MJ, Houbiers JG, Verschueren P et al (2012) Safety, tolerability, pharmacokinetics, pharmacodynamics and efficacy of the monoclonal antibody ASK8007 blocking osteopontin in patients with rheumatoid arthritis: a randomised, placebo controlled, proof-of-concept study. Ann Rheum Dis 71:180–185
    • (2012) Ann Rheum Dis , vol.71 , pp. 180-185
    • Boumans, M.J.1    Houbiers, J.G.2    Verschueren, P.3


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