Expression of osteopontin messenger RNA and protein in rheumatoid arthritis: Effects of osteopontin on the release of collagenase 1 from articular chondrocytes and synovial fibroblasts

Arthritis and Rheumatism

Volumn 43, Issue 7, 2000, Pages 1597-1605

  Petrow, Peter K ^a,b,d   Hummel, Klaus M ^e   Schedel, Jörg ^e   Franz, Juliane K ^e   Klein, Christoph L ^b   Müller Ladner, Ulf ^e   Kriegsmann, Jörg ^b   Chang, Pi Ling ^c   Prince, Charles W ^c   Gay, Renate E ^e   Gay, Steffen ^e  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b JOHANNES GUTENBERG UNIVERSITY   (Germany)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^d FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^e NONE

Author keywords

[No Author keywords available]

Indexed keywords

CD45 ANTIGEN; CD68 ANTIGEN; COLLAGENASE; MESSENGER RNA; OSTEOPONTIN; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE;

ADULT; AGED; ARTICLE; CARTILAGE CELL; CELL INVASION; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FIBROBLAST; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RHEUMATOID ARTHRITIS; SYNOVIUM;

AGED; ANIMALS; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC; ARTHRITIS, RHEUMATOID; CELLS, CULTURED; CHONDROCYTES; FEMALE; FIBROBLASTS; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; MATRIX METALLOPROTEINASE 1; MIDDLE AGED; OSTEOPONTIN; PROCOLLAGEN-PROLINE DIOXYGENASE; RATS; RECOMBINANT PROTEINS; RNA, MESSENGER; SIALOGLYCOPROTEINS; SYNOVIAL MEMBRANE;

EID: 0033923116     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/1529-0131(200007)43:7<1597::AID-ANR25>3.0.CO;2-0     Document Type: Article

References (48)

1. Hu DD, Lin EC, Kovach NL, Hoyer JR, Smith JW. A biochemical characterization of the binding of osteopontin to integrins αvβ1 and αvβ5. J Biol Chem 1995;270:26232-8.
2. Somerman MJ, Prince CW, Butler WT, Foster RA, Moehring JM, Sauk JJ. Cell attachment activity of the 44 kilodalton bone phosphoprotein is not restricted to bone cells. Matrix 1989,9:49-54.
3. Liaw L, Almeida M, Hart CE, Schwartz SM, Giachelli CM. Osteopontin promotes vascular cell adhesion and spreading and is chemotactic for smooth muscle cells in vitro. Circ Res 1994;74: 214-24.
4. Miyauchi A, Alvarez J, Greebfield EM, Teti A, Grano M, Colucci S, et al. Recognition of osteopontin and related peptides by αvβ3 integrin stimulates immediate cell signals in osteoclasts. J Biol Chem 1991;266:20369-74.
5. Hruska KA, Rolnick F, Huskeya M, Alvarez U, Cheresh D. Engagement of the osteoclast integrin alpha v beta 3 by osteopontin stimulates phosphatidylinositol 3-hydroxyl kinase activity. Endocrinology 1995;136:2984-92.
6. Chellaiah M, Fitzgerald C, Filardo EJ, Cheresh DA, Hruska KA. Osteopontin activation of c-src in human melanoma cells requires the cytoplasmic domain of the integrin alpha v-subunit. Endocrinology 1996;137:2432-49.
7. Prince CW, Oosawa T, Butler WT, Tomana M, Bhown AS, Bhown M, et al. Isolation, characterization, and biosynthesis of a phosphorylated glycoprotein from rat bone. J Biol Chem 1987;262: 2900-7.
8. Oldberg A, Franzen A, Heinegard D. Cloning and sequence analysis of rat bone sialoprotein (osteopontin) cDNA reveals an Arg-Gly-Asp cell-binding sequence. Proc Natl Acad Sci U S A 1986;83:8819-23.
9. Rodan GA. Osteopontin overview. Ann N Y Acad Sci 1995;760:1-5.
10. Patarca R, Freeman GJ, Singh RP, Wei FY, Durfee T, Blattner F, et al. Structural and functional studies of the early T lymphocyte activation 1 (Eta-1) gene: definition of a novel T cell-dependent response associated with genetic resistance to bacterial infection. J Exp Med 1989;170:145-61.
11. Murry CE, Giachelli CM, Schwartz SM, Vracko R. Macrophages express osteopontin during repair of myocardial necrosis. Am J Pathol 1994;145:1450-62.
12. McKee MD, Nanci A. Secretion of osteopontin by macrophages and its accumulation at tissue surfaces during wound healing in mineralized tissues: a potential requirement for macrophage adhesion and phagocytosis. Anat Rec 1996;245:394-409.
13. Hirota S, Imakita M, Kohri K, Ito A, Morii E, Adachi S, et al. Expression of osteopontin messenger RNA by macrophages in atherosclerotic plaques. Am J Pathol 1993;143:1003-8.
14. Ikeda T, Shirasawa T, Esaki Y, Yoshiki S, Hirokawa K. Osteopontin mRNA is expressed by smooth muscle-derived foam cells in human atherosclerotic lesions of the aorta. J Clin Invest 1993;92: 2814-20.
15. Senger DR, Asch BB, Smith BD, Peruzzi CA, Dvorak HF. A secreted phosphoprotein marker for neoplastic transformation of both epithelial and fibroblastic cells. Nature 1983;302:714-5.
16. Craig AM, Nemir M, Mukherjee BB, Chambers AF, Denhardt DT. Identification of the major phosphoprotein secreted by many rodent cell lines as 2ar/osteopontin: enhanced expression in H-ras-transformed 3T3 cells. Biochem Biophys Res Commun 1988;157: 166-73.
17. Brown LF, Papadopoulos-Sergiou A, Berse B, Manseau EJ, Tognazzi K, Perruzzi CA, et al. Osteopontin expression and distribution in human carcinomas. Am J Pathol 1994;145:610-23.
18. Gillespie MT, Thomas RJ, Pu ZY, Zhou H, Martin TJ, Findlay DM. Calcitonin receptors, bone sialoprotein and osteopontin are expressed in primary breast cancers. Int J Cancer 1997;73:812-5.
19. Craig AM, Bowden GT, Chambers AF, Spearman MA, Greenberg AH, Wright JA, et al. Secreted phosphoprotein mRNA is induced during multi-stage carcinogenesis in mouse skin and correlates with the metastatic potential of murine fibroblasts. Int J Cancer 1990;46:133-7.
20. Werb Z, Tremble PM, Behrendtsen O, Crowley E, Damsky CH. Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression. J Cell Biol 1989;109:877-89.
21. Arner EC, Tortorella MD. Signal transduction through chondrocyte integrin receptors induces matrix metalloproteinase synthesis and synergizes with interleukin-1. Arthritis Rheum 1995;38:1304-14.
22. Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988;31:315-24.
23. Lasa M, Chang PL, Prince CW, Pinna LA. Phosphorylation of osteopontin by Golgi apparatus casein kinase. Biochem Biophys Res Commun 1997;240:602-5.
24. Kiefer MC, Bauer DM, Barr PJ. The cDNA and derived amino acid sequence for human osteopontin. Nucleic Acids Res 1989;17:3306.
25. Falini B, Flenghi L, Pileri S, Gambacorta M, Bigerna E, Durkop H, et al. PG-M1: a new monoclonal antibody directed against a fixative-resistant epitope on the macrophage-restricted form of the CD68 molecule. Am J Pathol 1993;142:1359-72.
26. Devoll RE, Li W, Woods KV, Pinero GJ, Butler WT, Farach-Carson MC, et al. Osteopontin (OPN) distribution in premalignant and malignant lesions of oral epithelium and expression in cell lines derived from squamous cell carcinoma of the oral cavity. J Oral Pathol Med 1999;28:97-101.
27. Kriegsmann J, Keyszer G, Geiler T, Gay RE, Gay S. A new double labeling technique for combined in situ hybridization and immunohistochemical analysis. Lab Invest 1994;71:911-7.
28. Roth J, Saremaslani P, Warhol MJ, Heitz PU. Improved accuracy in diagnostic immunohistochcmistry, lectin histochemistry and in situ hybridization using a gold-labeled horseradish peroxidase antibody and silver intensification. Lab Invest 1992;67:263-9.
29. Dodds RA, Connor JR, James IE, Rykaczewski EL, Appelbaum E, Dul E. et al. Human osteoclast, not osteoblasts, deposit osteopontin onto resorption surfaces: an in vitro and ex vivo study of remodeling bone. J Bone Miner Res 1995;10:1666-80.
30. Sugimoto M, Hirota S, Sato M, Kawahata H, Tsukamoto I, Yasui N, et al. Impaired expression of noncollagenous bone matrix protein mRNAs during fracture healing in ascorbic acid-deficient rats. J Bone Mineral Res 1998;13:271-8.
31. Ashizawa N, Graf K, Do YS, Nunohiro T, Giachelli CM, Meehan WP, et al. Osteopontin is produced by rat cardiac fibroblasts and mediates AII-induced DNA synthesis and collagen contraction. J Clin Invest 1996;98:2218-27.
32. Chambers AF, Behrend EI, Wilson SM, Denhardt DT. Induction of expression of osteopontin (OPN; secreted phosphoprotcin) in metastatic, ras-transformcd NIH 3T3 cells. Anticancer Res 1992;12:43-7.
33. Lafyatis R, Remmers EF, Roberts AB, Yocum DE, Sporn MB, Wilder RL. Anchorage-independent growth of synoviocytes from arthritic and normal joints: stimulation by exogenous platelet-derived growth factor and inhibition by transforming growth factor-β and retinoids. J Clin Invest 1989;83:1267-76.
34. Müller-Ladner U, Kriegsmann J, Gay RE, Gay S. Oncogenes in rheumatoid arthritis. Rheum Dis Clin North Am 1995;21:675-90.
35. Trabandt A, Aicher WK, Gay RE, Sukhatme VP, Nilson-Hamilton M, Hamilton RT, et al. Expression of the collagenolytic and ras-induced cysteine proteinase cathepsin L and proliferation-associated oncogenes in synovial cells of MRL/I mice and patients with rheumatoid arthritis. Matrix 1990;10:349-61.
36. Müller-Ladner U, Kriegsmann J, Franklin BN, Matsumoto S, Geiler T, Gay RE, et al. Synovial fibroblasts of patients with rheumatoid arthritis attach to and invade normal human cartilage when engrafted into SCID mice. Am J Pathol 1996;149:1607-15.
37. Mulherin D, FitzGerald O, Bresnihan B. Synovial tissue macrophage populations and articular damage in rheumatoid arthritis. Arthritis Rheum 1996;39:115-24.
38. Firestein GS. Cytokines in autoimmune diseases. Concepts Immunopathol 1992;8:129-60.
39. Weber GF, Ashkar S, Glimcher MJ, Cantor H. Receptor-ligand interaction between CD44 and osteopontin. Science 1996;271: 509-12.
40. Woods VL Jr, Schreck PJ, Gesink DS, Pacheco HO, Amiel D, Akeson WH, et al. Integrin expression by human articular chondrocytes. Arthritis Rheum 1994;37:537-44.
41. Grover J, Roughley PJ. Expression of cell-surface proteoglycan mRNA by human articular chondrocytes. Biochem J 1995;309:963-8.
42. Loeser RF. Integrin-mediated attachment of articular chondrocytes to extracellular matrix proteins. Arthritis Rheum 1993;36: 1103-10.
43. Nikkari L, Haapasalmi K, Aho H, Torvinen A, Sheppard D, Larjava H, et al. Localization of the av subfamily of integrins and their putative ligands in synovial lining layer. J Rheumatol 1995; 22:16-23.
44. Chambers AF, Hota C, Prince CW. Adhesion of metastatic, ras-transformed NIH 3T3 cells to osteopontin, fibronectin, and laminin. Cancer Res 1993;53:701-6.
45. Singh RP, Patarca R, Schwartz J, Singh P, Cantor H. Definition of a specific interaction between the early T lymphocyte activation 1 (Eta-1) protein and murine macrophages in vitro and its effect upon macrophages in vivo. J Exp Med 1990;171:1931-42.
46. Pichler R, Giachelli CM, Lombardi D, Pippin J, Gordon K, Alpers CE, et al. Tubulointerstitial disease in glomerulonephritis: potential role of osteopontin (uropontin). Am J Pathol 1994;144:915-26.
47. Lampe MA, Patarca R, Iregui MV, Cantor H. Polyclonal B cell activation by the Eta-1 cytokine and the development of systemic autoimmune disease. J Immunol 1991;147:2902-6.
48. Gay S, Gay RE, Koopman WJ. Molecular and cellular mechanisms of joint destruction: two cellular mechanisms explain joint destruction? Ann Rheum Dis 1993;52:839-47.