Effect of Saikokeishito, a Kampo medicine, on hydrogen peroxide-induced premature senescence of normal human dermal fibroblasts

Journal of Integrative Medicine

Volumn 12, Issue 6, 2014, Pages 495-503

  Takata, Takanobu ^a   Motoo, Yoshiharu ^a   Tomosugi, Naohisa ^a  

^a KANAZAWA MEDICAL UNIVERSITY   (Japan)

Author keywords

fibroblasts; Kampo; medicine; p53; premature senescence; Saikokeishito

Indexed keywords

AMP ACTIVATED PROTEIN KINASE ALPHA1; AMP ACTIVATED PROTEIN KINASE ALPHA2; ASCORBIC ACID; HYDROGEN PEROXIDE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; KAMPO; PROTEIN P53; SHOSAIKOTO GO KEISHIKASHAKUYAKUTO; SIRTUIN 1; STRATIFIN; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; ANTIOXIDANT; HERBACEOUS AGENT; PRKAA1 PROTEIN, HUMAN; SAIKO-KEISHI-TO; SIRT1 PROTEIN, HUMAN;

ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CYSTIC FIBROSIS; DERMIS; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; HUMAN; HUMAN CELL; IN VIVO STUDY; OXIDATIVE STRESS; PREMATURE AGING; PROTEIN EXPRESSION; SENESCENCE; SKIN FIBROBLAST; SKIN PROTECTION; UPREGULATION; CELL AGING; CELL SURVIVAL; CHINESE MEDICINE; CULTURE TECHNIQUE; DRUG EFFECTS; FIBROBLAST; METABOLISM; PROCEDURES;

AMP-ACTIVATED PROTEIN KINASES; ANTIOXIDANTS; ASCORBIC ACID; CELL AGING; CELL CULTURE TECHNIQUES; CELL SURVIVAL; DERMIS; DOWN-REGULATION; DRUGS, CHINESE HERBAL; FIBROBLASTS; HUMANS; HYDROGEN PEROXIDE; MEDICINE, KAMPO; SIRTUIN 1; UP-REGULATION;

EID: 84925228432     PISSN: 20954964     EISSN: None     Source Type: Journal    
DOI: 10.1016/S2095-4964(14)60052-2     Document Type: Article

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