Synthesis and characterization of silk fibroin microparticles for intra-articular drug delivery

International Journal of Pharmaceutics

Volumn 485, Issue 1-2, 2015, Pages 7-14

  Mwangi, Timothy K ^a   Bowles, Robby D ^a   Tainter, David M ^b   Bell, Richard D ^b   Kaplan, David L ^c   Setton, Lori A ^a,b  

^a Duke University   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

^c Tufts University   (United States)

Author keywords

Drug delivery; In vivo imaging; Intra articular; Microparticles; Osteoarthritis; Silk fibroin

Indexed keywords

CYANINE DYE; CYANINE DYE 7; NANOCARRIER; SILK FIBROIN; UNCLASSIFIED DRUG; CARBOCYANINE; DELAYED RELEASE FORMULATION; DRUG CARRIER; FIBROIN; FLUORESCENT DYE; INDOTRICARBOCYANINE;

ARTICLE; DRUG HALF LIFE; DRUG RETENTION; FLUORESCENCE IMAGING; IMAGE ANALYSIS; IN VITRO STUDY; IN VIVO STUDY; JOINT CAVITY; KNEE; MALE; NANOANALYSIS; NANOEMULSION; NANOFABRICATION; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; RAT; SCANNING ELECTRON MICROSCOPY; SUSTAINED DRUG RELEASE; ANIMAL; CHEMISTRY; DELAYED RELEASE FORMULATION; EVALUATION STUDY; HALF LIFE TIME; INTRAARTERIAL DRUG ADMINISTRATION; JOINT; MEDICINAL CHEMISTRY; METABOLISM; PHARMACEUTICS; PROCEDURES; SOLUBILITY; SPRAGUE DAWLEY RAT; TISSUE DISTRIBUTION;

ANIMALS; CARBOCYANINES; CHEMISTRY, PHARMACEUTICAL; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; FIBROINS; FLUORESCENT DYES; HALF-LIFE; INJECTIONS, INTRA-ARTERIAL; JOINTS; MALE; PARTICLE SIZE; RATS, SPRAGUE-DAWLEY; SOLUBILITY; TECHNOLOGY, PHARMACEUTICAL; TISSUE DISTRIBUTION;

EID: 84925068156     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2015.02.059     Document Type: Article

References (50)

1. S.B. Adams Jr., M.F. Shamji, D.L. Nettles, P. Hwang, and L.A. Setton Sustained release of antibiotics from injectable and thermally responsive polypeptide depots J. Biomed. Mater. Res. Part B Appl. Biomater. 90 1 2009 67 74
2. D.D. Allen, and C.A. Cott Evaluating rehabilitation outcomes from the client's perspective by identifying the gap between current and preferred movement ability Disabil. Rehabil. 32 2010 452 461
3. K.D. Allen, S.B. Adams Jr., B.A. Mata, M.F. Shamji, E. Gouze, L. Jing, D.L. Nettles, L.D. Latt, and L.A. Setton Gait and behavior in an IL1beta-mediated model of rat knee arthritis and effects of an IL1 antagonist J. Orthop. Res. 29 2011 694 703
4. G.H. Altman, F. Diaz, C. Jakuba, T. Calabro, R.L. Horan, J. Chen, H. Lu, J. Richmond, and D.L. Kaplan Silk-based biomaterials Biomaterials 24 2003 401 416
5. T.F.G. Arai, R. Innocenti, and M. Tsukada Biodegradation of B. mori silk fibroin fibers and films J. Appl. Polym. Sci. 91 2004 2383 2390
6. X. Ayral Injections in the treatment of osteoarthritis Best Pract. Res. Clin. Rheumatol. 15 4 2001
7. H. Betre, W. Liu, M.R. Zalutsky, A. Chilkoti, V.B. Kraus, and L.A. Setton A thermally responsive biopolymer for intra-articular drug delivery J. Control. Release 115 2006 175 182
8. R. Bitton The economic burden of osteoarthritis Am. J. Manag. Care 2009 S230 S235
9. R.D. Bowles, B.A. Mata, R.D. Bell, T.K. Mwangi, J.L. Huebner, V.B. Kraus, and L.A. Setton In Vivo luminescent imaging of NF-kappaB activity and serum cytokine levels predict pain sensitivities in a rodent model of osteoarthritis Arthritis Rheum. 2013
10. N. Butoescu, O. Jordan, P. Burdet, P. Stadelmann, A. Petri-Fink, H. Hofmann, and E. Doelker Dexamethasone-containing biodegradable superparamagnetic microparticles for intra-articular administration: physicochemical and magnetic properties, in vitro and in vivo drug release Eur. J. Pharma. Biopharm. 72 2009 529 538
11. N. Butoescu, O. Jordan, and E. Doelker Intra-articular drug delivery systems for the treatment of rheumatic diseases: a review of the factors influencing their performance Eur. J. Pharma. Biopharm. 73 2009 205 218
12. Y. Cao, and B. Wang Biodegradation of silk biomaterials Int. J. Mol. Sci. 10 2009 1514 1524
13. S.B. Christensen, I. Reimann, O. Henriksen, and C.C. Arnoldi Experimental osteoarthritis in the rabbit. A study of 133xenon washout rates from the synovial cavity Acta Orthop. Scand. 53 1982 167 174
14. J.L. Denlinger Metabolism of sodium hyaluronate in articular and ocular tissues Doctoral Dissertation 1982 Université de Sciences et Techniques de Lille Lille
15. C.H. Evans, V.B. Kraus, and L.A. Setton Progress in intra-articular therapy Nat. Rev. Rheumatol. 10 2014 11 22
16. N. Gerwin, C. Hops, and A. Lucke Intraarticular drug delivery in osteoarthritis Adv. Drug Deliv. Rev. 58 2006 226 242
17. A.S. Gobin, R. Rhea, R.A. Newman, and A.B. Mathur Silk-fibroin-coated liposomes for long-term and targeted drug delivery Int. J. Nanomed. 1 2006 81 87
18. S. Hofmann, C.T. Foo, F. Rossetti, M. Textor, G. Vunjak-Novakovic, D.L. Kaplan, H.P. Merkle, and L. Meinel Silk fibroin as an organic polymer for controlled drug delivery J. Control. Release 111 2006 219 227
19. R.L. Horan, K. Antle, A.L. Collette, Y. Wang, J. Huang, J.E. Moreau, V. Volloch, D.L. Kaplan, and G.H. Altman In vitro degradation of silk fibroin Biomaterials 26 2005 3385 3393
20. E. Horisawa, T. Hirota, S. Kawazoe, J. Yamada, H. Yamamoto, H. Takeuchi, and Y. Kawashima Prolonged anti-inflammatory action of DL-lactide/glycolide copolymer nanospheres containing betamethasone sodium phosphate for an intra-articular delivery system in antigen-induced arthritic rabbit Pharma. Res. 19 2002 403 410
21. E. Horisawa, K. Kubota, I. Tuboi, K. Sato, H. Yamamoto, H. Takeuchi, and Y. Kawashima Size-dependency of DL-lactide/glycolide copolymer particulates for intra-articular delivery system on phagocytosis in rat synovium Pharma. Res. 19 2002 132 139
22. A. Hough Jr. Pathology of osteoarthritis. Arthritis and allied conditions A Textbook of Rheumatology 2005 Lippincott Williams & Wilkins Philadelphia
23. A. Jones, and M. Doherty Intra-articular glucocorticoids and other injection therapies Osteoarthritis 2003 Oxford University Press New York
24. M.L. Kang, and G.I. Im Drug delivery systems for intra-articular treatment of osteoarthritis Expert Opin. Drug Deliv. 11 2014 269 282
25. U.J. Kim, J. Park, H.J. Kim, M. Wada, and D.L. Kaplan Three-dimensional aqueous-derived biomaterial scaffolds from silk fibroin Biomaterials 26 2005 2775 2785
26. A.B.A.M. Kumar, R.C. Blanks, and N. Bodick Sustained Efficacy of Intra-articular FX006 In a Rat Model of Osteoarthritis Osteoarthritis Cartilage 20 2013 S289
27. A.S. Lammel, X. Hu, S.H. Park, D.L. Kaplan, and T.R. Scheibel Controlling silk fibroin particle features for drug delivery Biomaterials 31 2010 4583 4591
28. L.S. Liang, J. Jackson, W. Min, V. Risovic, K.M. Wasan, and H.M. Burt Methotrexate loaded poly(l-lactic acid) microspheres for intra-articular delivery of methotrexate to the joint J. Pharma. Sci. 93 2004 943 956
29. R.T. Liggins, T. Cruz, W. Min, L. Liang, W.L. Hunter, and H.M. Burt Intra-articular treatment of arthritis with microsphere formulations of paclitaxel: biocompatibility and efficacy determinations in rabbits Inflamm. Res. 53 2004 363 372
30. F. Lopez-Garcia, J.M. Vazquez-Auton, F. Gil, R. Latoore, F. Moreno, J. Villalain, and J.C. Gomez-Fernandez Intra-articular therapy of experimental arthritis with a derivative of triamcinolone acetonide incorporated in liposomes J. Pharm. Pharmacol. 45 1993 576 578
31. Q. Lu, B. Zhang, M. Li, B. Zuo, D.L. Kaplan, Y. Huang, and H. Zhu Degradation mechanism and control of silk fibroin Biomacromolecules 12 2011 1080 1086
32. L. Meinel, S. Hofmann, V. Karageorgiou, C. Kirker-Head, J. McCool, G. Gronowicz, L. Zichner, R. Langer, G. Vunjak-Novakovic, and D.L. Kaplan The inflammatory responses to silk films in vitro and in vivo Biomaterials 26 2005 147 155
33. L. Meinel, and D.L. Kaplan Silk constructs for delivery of musculoskeletal therapeutics Adv. Drug Deliv. Rev. 64 2012 1111 1122
34. K. Numata, and D.L. Kaplan Silk-based delivery systems of bioactive molecules Adv. Drug Deliv. Rev. 62 2010 1497 1508
35. S.G. Owen, H.W. Francis, and M.S. Roberts Disappearance kinetics of solutes from synovial fluid after intra-articular injection Br. J. Clin. Pharmacol. 38 4 1994
36. D.P. Page-Thomas, D. Bard, B. King, and J.T. Dingle Clearance of proteoglycan from joint cavities Ann. Rheum. Dis. 46 1987 934 937
37. A.R. Poole, and D.S. Howell Etiopathogenesis of osteoarthritis Osteoarthritis. Diagnosis and Medical/Surgical Management 2001 W.B. Saunders Company Philadelphia
38. J.H. Ratcliffe, I.M. Hunneyball, C.G. Wilson, A. Smith, and S.S. Davis Albumin microspheres for intra-articular drug delivery: investigation of their retention in normal and arthritic knee joints of rabbits J. Pharm. Pharmacol. 39 1987 290 295
39. D.N. Rockwood, R.C. Preda, T. Yucel, X. Wang, M.L. Lovett, and D.L. Kaplan Materials fabrication from Bombyx mori silk fibroin Nat. Protoc. 6 2011 1612 1631
40. G.P. Rodnan, and M.J. Maclachlan The absorption of serum albumin and gamma globulin from the knee joint of man and rabbit Arthritis Rheum. 3 1960 152 157
41. P.A. Simkin, and R.S. Benedict Iodide and albumin kinetics in normal canine wrists and knees Arthritis Rheum. 33 1990 73 79
42. P. Srihanam, W. Simcheur, and Y. Srisuwan Study on silk sericin and chitosan blend film: morphology and secondary structure characterizations Pak. J. Biol. Sci. 12 2009 1487 1490
43. H. Thakkar, R.K. Sharma, A.K. Mishra, K. Chuttani, and R.S. Murthy Celecoxib incorporated chitosan microspheres: in vitro and in vivo evaluation J. Drug Target. 12 2004 549 557
44. S. Turker, S. Erdogan, A.Y. Ozer, E.L. Ergun, M. Tuncel, H. Bilgili, and S. Deveci Scintigraphic imaging of radiolabelled drug delivery systems in rabbits with arthritis Int. J. Pharma. 296 2005 34 43
45. C. Vepari, and D.L. Kaplan Silk as a Biomaterial Prog. Polym. Sci. 32 8-9 2007 991 1007
46. W.J. Wallis, P.A. Simkin, W.B. Nelp, and D.M. Foster Intraarticular volume and clearance in human synovial effusions Arthritis Rheum. 28 1985 441 449
47. X. Wang, T. Yucel, Q. Lu, X. Hu, and D.L. Kaplan Silk nanospheres and microspheres from silk/pva blend films for drug delivery Biomaterials 31 2010 1025 1035
48. R.E. Whitmire, D.S. Wilson, A. Singh, M.E. Levenston, N. Murthy, and A.J. Garcia Self-assembling nanoparticles for intra-articular delivery of anti-inflammatory proteins Biomaterials 33 2012 7665 7675
49. S.M. Wigginton, B.C. Chu, M.H. Weisman, and S.B. Howell Methotrexate pharmacokinetics after intrarticular injection in patients with rheumatoid arthritis Arthritis Rheum. 23 1980 119 122
50. W. Zhang, R.W. Moskowitz, G. Nuki, S. Abramson, R.D. Altman, N. Arden, S. Bierma-Zeinstra, K.D. Brandt, P. Croft, M. Doherty, M. Dougados, M. Hochberg, D.J. Hunter, K. Kwoh, L.S. Lohmander, and P. Tugwell OARSI recommendations for the management of hip and knee osteoarthritis, Part II: OARSI evidence-based, expert consensus guidelines Osteoarthritis Cartilage 16 2008 137 162