Acute nitrogen dioxide inhalation induces mitochondrial dysfunction in rat brain

Environmental Research

Volumn 138, Issue , 2015, Pages 416-424

  Yan, Wei ^a   Ji, Xiaotong ^a   Shi, Jing ^a   Li, Guangke ^a   Sang, Nan ^a  

^a SHANXI UNIVERSITY   (China)

Author keywords

Biogenesis; Energy metabolism; Mitochondria; Nitrogen dioxide; Reactive oxygen species

Indexed keywords

3,4 METHYLENEDIOXYAMPHETAMINE; CYTOCHROME C OXIDASE; NITROGEN DIOXIDE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; REACTIVE OXYGEN METABOLITE; SUCCINATE DEHYDROGENASE; SUCCINATE DEHYDROGENASE (UBIQUINONE); TRANSCRIPTION FACTOR; AIR POLLUTANT;

ABNORMALITY; APOPTOSIS; BRAIN; CYTOCHROME; ENZYME ACTIVITY; FREE RADICAL; METABOLISM; MITOCHONDRION; NEUROLOGY; NITROGEN DIOXIDE; OXYGEN; RISK FACTOR; RODENT; TOXICITY; ULTRASTRUCTURE;

AIR POLLUTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BIOGENESIS; BRAIN CORTEX; BRAIN INJURY; CELL STRESS; CELL STRUCTURE; CELL ULTRASTRUCTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENERGY METABOLISM; ENERGY YIELD; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVITY; INHALATION; MALE; MITOCHONDRIAL GENE; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; NEUROTOXICITY; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RAT; RESPIRATORY CHAIN; RISK ASSESSMENT; RISK FACTOR; WISTAR RAT; AIR POLLUTANT; ANIMAL; BRAIN; CHEMICALLY INDUCED; DOSE RESPONSE; DRUG EFFECTS; ENZYMOLOGY; EXPOSURE; PHYSIOLOGY; TOXICITY; ULTRASTRUCTURE;

RATTUS;

AIR POLLUTANTS; ANIMALS; BRAIN; BRAIN INJURIES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENERGY METABOLISM; INHALATION EXPOSURE; MALE; MITOCHONDRIA; NITROGEN DIOXIDE; RATS; RATS, WISTAR;

EID: 84924957632     PISSN: 00139351     EISSN: 10960953     Source Type: Journal    
DOI: 10.1016/j.envres.2015.02.022     Document Type: Article

References (52)

1. Achanta G., Sasaki R., Feng L., Carew J.S., Lu W., Pelicano H., et al. Novel role of p53 in maintaining mitochondrial genetic stability through interaction with DNA Pol gamma. EMBO J. 2005, 24:3482-3492.
2. Afanas'ev I.B. Signaling functions of free radicals superoxide & nitric oxide under physiological & pathological conditions. Mol Biotechnol. 2007, 37:2-4.
3. Akimoto H. Global air quality and pollution. Science 2003, 302:1716-1719.
4. Andersson U., Scarpulla R.C. Pgc-1-related coactivator, a novel, serum-inducible coactivator of nuclear respiratory factor 1-dependent transcription in mammalian cells. Mol Cell Biol. 2001, 21:3738-3749.
5. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 1976, 72:248-254.
6. Calabrese V., Lodi R., Tonon C., D'Agata V., Sapienza M., Scapagnini G., et al. Oxidative stress, mitochondrial dysfunction and cellular stress response in Friedreich's ataxia. J. Neurol. Sci. 2005, 233:145-162.
7. Campbell C.T., Kolesar J.E., Kaufman B.A. Mitochondrial transcription factor A regulates mitochondrial transcription initiation, DNA packaging, and genome copy number. Biochim. Biophys. Acta 2012, 1819:921-929.
8. Chan C.K., Yao X.H. Air pollution in mega cities in China. Atmos. Environ. 2008, 1-42.
9. Chauhan V., Chauhan A. Oxidative stress in Alzheimer's disease. Pathophysiology 2006, 13:195-208.
10. Colicino E., Power M.C., Cox D.G., Weisskopf M.G., Hou L., Alexeeff S.E., et al. Mitochondrial haplogroups modify the effect of black carbon on age-related cognitive impairment. Environ. Health 2014, 13:42.
11. Crouch P.J., Harding S.M., White A.R., Camakaris J., Bush A.I., Masters C.L. Mechanisms of A beta mediated neurodegeneration in Alzheimer's disease. Int. J. Biochem. Cell Biol. 2008, 40:81-98.
12. Dominy J.E., Lee Y., Gerhart-Hines Z., Puigserver P. Nutrient-dependent regulation of PGC-1alpha's acetylation state and metabolic function through the enzymatic activities of Sirt1/GCN5. Biochim. Biophys. Acta 2010, 1804:1676-1683.
13. Dröge W. Free radicals in the physiological control of cell function. Physiol. Rev. 2002, 82:47-95.
14. Esteban M.A., Wang T., Qin B., Yang J., Qin D., Cai J., et al. Vitamin C enhances the generation of mouse and human induced pluripotent stem cells. Cell Stem. Cell. 2010, 6(1):71-79. Jan 8.
15. 2 on lipids and lipid peroxidation in the CNS of the guinea-pig. Pharmacol. Toxicol. 1990, 66:146-149.
16. Fiskum G., Murphy A.N., Beal M.F. Mitochondria in neurodegeneration: acute ischemia and chronic neurodegenerative diseases. J. Cereb. Blood Flow Metab. 1999, 19:351-369.
17. Frampto M.W., Boscia J., Roberts N.J., Azadniv M., Torres A., Cox C., et al. Nitrogen dioxide exposure: effects on airway and blood cells. Am. J. Physiol. Lung Cell Mol. Physiol. 2002, 282:L155-L165.
18. Franco M.C., Antico, Arciuch V.G., Peralta J.G., Galli S., Levisman D., López L.M., et al. Hypothyroid phenotype is contributed by mitochondrial complex I inactivation due to translocated neuronal nitric-oxide synthase. J. Biol. Chem. 2006, 281:4779-4786.
19. Fukui H., Moraes C.T. The mitochondrial impairment, oxidative stress and neurodegeneration connection: reality or just an attractive hypothesis?. Trends Neurosci. 2008, 31:251-256.
20. Giorgio M., Trinei M., Migliaccio E., Pelicci P.G. Hydrogen peroxide: a metabolic by-product or a common mediator of ageing signals?. Nat. Rev. Mol. Cell Biol. 2007, 8:722-728.
21. Hoppins S. The regulation of mitochondrial dynamics. Curr. Opin. Cell Biol. 2014, 29:46-52.
22. Huang X., Zhao Q., Chen D., Zhang L. Determination of reactive oxygen species, total superoxide dismutase and manganese superoxide dismutase in serum and tissue of primary hepatocellular carcinoma patients. Lab Med. 2004, 19(5):399-402.
23. Hussain I., Jain V.V., O'Shaughnessy P., Businga T.R., Kline J. Effect of nitrogen dioxide exposure on allergic asthma in a murine model. Chest 2004, 126:198-204.
24. Johar K., Priya A., Wong-Riley M.T. Regulation of Na(+)/K(+)-ATPase by nuclear respiratory factor 1: implication in the tight coupling of neuronal activity, energy generation, and energy consumption. J. Biol. Chem. 2012, 287:40381-40390.
25. Jung C.R., Lin Y.T., Hwang B.F. Air pollution and newly diagnostic autism spectrum disorders: a population-based cohort study in Taiwan. PLoS One. 2013, 8:e75510.
26. 2 and children's neurodevelopment from birth to 24 months of age: mothers and Children's Environmental Health (MOCEH) study. Sci. Total Environ. 2014, 481:439-445.
27. Kumie A., Emmelin A., Wahlberg S., Berhane Y., Ali A., Mekonen E., et al. Sources of variation for indoor nitrogen dioxide in rural residences of Ethiopia. Environ. Health 2009, 8:51.
28. LeBel C.P., Ischiropoulos H., Bondy S.C. Evaluation of the probe 2,7-dichiorofluorescin as an indicator of reactive oxygen species formation and oxidative stress. Chem. Res. Toxicol. 1992, 5(2):227-231.
29. Lee T.T. Effect of ozone on swelling of tobacco mitochondria. Plant Physiol. 1968, 43:133-139.
30. Leyssens A., Nowicky A.V., Patterson L., Crompton M., Duchen M.R. The relationship between mitochondrial state, ATP hydrolysis, [Mg2+]i and [Ca2+]i studied in isolated rat cardiomyocytes. J. Physiol. 1996, 496:111-128.
31. Li H., Chen L., Guo Z., Sang N., Li G. In vivo screening to determine neurological hazards of nitrogen dioxide (NO2) using Wistar rats. J. Hazard Mater. 2012, 225-226:46-53.
32. Li H., Xin X. Nitrogen dioxide (NO(2)) pollution as a potential risk factor for developing vascular dementia and its synaptic mechanisms. Chemosphere 2013, 92:52-58.
33. Li N., Sioutas C., Cho A., Schmitz D., Misra C., Sempf J., et al. Ultrafine particulate pollutants induce oxidative stress and mitochondrial damage. Environ. Health Perspect. 2003, 111:455-460.
34. Liu Y., Peterson D.A., Kimura H., Schubert D. Mechanism of cellular 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction. J. Neurochem. 1997, 69:581-593.
35. Mattiasson G., Friberg H., Hansson M., Elmér E., Wieloch T. Flow cytometric analysis of mitochondria from CA1 and CA3 regions of rat hippocampus reveals differences in permeability transition pore activation. J. Neurochem. 2003, 87:532-544.
36. Mehndiratta M.M., Aggarwal P., Singal R.K., Munjal Y.P. Mitochondrial cytopathies. J. Assoc. Physicians India 2000, 48:417-420.
37. Meyer J.N., Leung M.C., Rooney J.P., Sendoel A., Hengartner M.O., Kisby G.E., et al. Mitochondria as a target of environmental toxicants. Toxicol. Sci. 2013, 134:1-17.
38. Morales E., Julvez J., Torrent M., de Cid R., Guxens M., Bustamante M., et al. Association of early-life exposure to household gas appliances and indoor nitrogen dioxide with cognition and attention behavior in preschoolers. Am. J. Epidemiol. 2009, 169:1327-1336.
39. Murphy M.P. How mitochondria produce reactive oxygen species. Biochem. J. 2009, 417:1-13.
40. Oyedotun K.S., Lemire B.D. The quaternary structure of the Saccharomyces cerevisiae succinate dehydrogenase. Homology modeling, cofactor docking, and molecular dynamics simulation studies. J. Biol. Chem. 2004, 279:9424-9431.
41. Pathmanathan S., Krishna M.T., Blomberg A., Helleday R., Kelly F.J., Sandström T., et al. Repeated daily exposure to 2ppm nitrogen dioxide upregulates the expression of IL-5, IL-10, IL-13, and ICAM-1 in the bronchial epithelium of healthy human airways. Occup. Environ. Med. 2003, 60:892-896.
42. Persinger R.L., Poynter M.E., Ckless K., Janssen-Heininger Y.M. Molecularmechanisms of nitrogen dioxide induced epithelial injury in the lung. Mol. Cell Biochem. 2002, 234-235:71-80.
43. Picone P., Nuzzo D., Caruana L., Scafidi V., Di Carlo M. Mitochondrial dysfunction: different routes to Alzheimer's disease therapy. Oxid. Med. Cell Longev. 2014, 2014:780179.
44. Qin G., Wang J., Huo Y., Yan H., Jiang C., Zhou J., et al. Sulfur dioxide inhalation stimulated mitochondrial biogenesis in rat brains. Toxicology 2012, 300:67-74.
45. Rech V.C., Feksa L.R., Dutra-Filho C.S., Wyse A.T., Wajner M., Wannmacher C.M. Inhibition of the mitochondrial respiratory chain by alanine in rat cerebral cortex. Metab Brain Dis. 2002, 17(3):123-130.
46. Schwarz T.L. Mitochondrial trafficking in neurons. Cold Spring Harb Perspect Biol. 2013, 5(6).
47. The modification of ambient air quality standards. GB3095-1996. 2000.
48. Valko M., Leibfritz D., Moncol J., Cronin M.T., Mazur M., Telser J. Free radicals and antioxidants in normal physiological functions and human disease. Int. J. Biochem. Cell Biol. 2007, 39:44-84.
49. Wang Z., Kou D., Li Z., He Y., Yu W., Du H. Effects of propofol-dexmedetomidine combination on ischemia reperfusion-induced cerebral injury. Neurorehabilitation 2014, 35(4):825-834. Jan 1.
50. Wong-Riley M.T. Cytochrome oxidase: an endogenous metabolic marker for neuronal activity. Trends Neurosci. 1989, 12:94-101.
51. Zhang A., Hao S., Bi J., Bao Y., Zhang X., An L., Jiang B. Effects of catalpol on mitochondrial function and working memory in mice after lipopolysaccharide-induced acute systemic inflammation. Exp. Toxicol. Pathol. Sep. 2009, 61(5):461-469.
52. 2) exposure influences development and progression of ischemic stroke. Toxicol. Lett. 2012, 214:120-130.