Effects of catalpol on mitochondrial function and working memory in mice after lipopolysaccharide-induced acute systemic inflammation

Experimental and Toxicologic Pathology

Volumn 61, Issue 5, 2009, Pages 461-469

  Zhang, Aihong ^a   Hao, Shuang ^a   Bi, Jing ^a   Bao, Yongming ^a   Zhang, Xiuli ^b   An, Lijia ^a   Jiang, Bo ^a  

^a DALIAN UNIVERSITY OF TECHNOLOGY   (China)

^b BINZHOU MEDICAL UNIVERSITY   (China)

Author keywords

Catalpol; Inflammation; Lipopolysaccharide; Mitochondria; NF B

Indexed keywords

CATALPOL; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BRAIN MITOCHONDRION; COGNITIVE DEFECT; CONTROLLED STUDY; DRUG EFFICACY; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL PERMEABILITY; MOUSE; NEUROPROTECTION; NONHUMAN; WORKING MEMORY;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BRAIN; GLUCOSIDES; INFLAMMATION; IRIDOIDS; LIPOPOLYSACCHARIDES; MAZE LEARNING; MEMORY; MICE; MITOCHONDRIA; NF-KAPPA B;

MUS;

EID: 68349144520     PISSN: 09402993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.etp.2008.10.010     Document Type: Article

References (38)

1. An S.J., Pae H.O., Oh G.S., Choi B.M., Jeong S., Jang S.I., et al. Inhibition of TNF-α, IL-1β, and IL-6 productions and NF-kB activation in lipopolysaccharide-activated RAW 264.7 macrophages by catalposide, an iridoid glycoside isolated from Catalpa ovata G. Don (Bignoniaceae). Int Immunopharmacol 2 (2002) 1173-1181
2. Angela R.K., Ronald G.C., Ananda P.D., Miroslaw B., Lidia G.-S., and de Leon M.J. Inflammation and Alzheimer's disease: possible role of periodontal diseases. Alzheimer's Dementia 4 (2007) 242-250
3. Avistur R., Pollak Y., and Yirmiya R. Different receptor mechanisms mediate the effects of endotoxin and interleukin-1 on female sexual behavior. Brain Res 773 (1997) 149-161
4. Bradford M.M. A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72 (1976) 248-254
5. + opens the mitochondrial permeability transition pore and releases cytochrome c in isolated mitochondria via an oxidative mechanism. Biochim Biophys Acta 1453 (1999) 49-62
6. Chen J., Buchanan J.B., Sparkman N.L., Godbout J.P., Freund G.G., and Johnson R.W. Neuroinflammation and disruption in working memory in aged mice after stimulation of the peripheral innate immune system. Brain Behav Immun 22 (2008) 301-311
7. Emanus R.K., Grunwald R., and Lemasters J.J. Rhodamin 123 as a probe of transmembrane potential in isolated rat-liver mitochondria: spectral and metabolic properties. Biochim Biophys Acta 850 (1986) 436-448
8. Florence N., Elisabeth R., Mohamed B., Bruno P., Michel P., Jean-Michel W., et al. Acute systemic inflammation induces central mitochondrial damage and mnesic deficit in adult Swiss mice. Neurosci Lett 424 (2007) 106-110
9. Godbout J.P., Chen J., Abraham J., Richwine A.R., Berg B.M., Kelley K.W., et al. Exaggerated neuroinflammation and sickness behavior in aged mice following activation of the peripheral innate immune system. FASEB J 19 (2005) 1329-1331
10. Godbout J.P., Berg B.M., Krzyszton C., and Johnson R.W. α-Tocopherol attenuates NF-κB activation and pro-inflammatory cytokine production in brain and improves recovery from lipopolysaccharide-induced sickness behavior. J Neuroimmunol 169 (2005) 97-105
11. Haddad J.J. Redox regulation of pro-inflammatory cytokines and IkappaB-alpha/NF-kappaB nuclear translocation and activation. Biochem Biophys Res Commun 296 (2002) 847-856
12. Haddad J.J., Safieh-Garabedian B., Saade N.E., and Lauterbach R. Inhibition of glutathione-related enzymes augments LPS-mediated cytokine biosynthesis: involvement of an IkappaB/NF-kappaB-sensitive pathway in the alveolar epithelium. Int Immunopharmacol 2 (2002) 1567-1583
13. Hamai D., Campbell A., and Bondy S.C. Modulation of oxidative events by multivalent manganese complexes in brain tissue. Free Radical Biol Med 31 (2001) 763-768
14. Hanisch U.K. Microglia as a source and target of cytokines. Glia 40 (2002) 140-155
15. Jiang B., Du J., Liu J.H., Bao Y.M., and An L.J. Catalpol attenuates the neurotoxicity induced by β-amyloid1-42 in cortical neuron-glia cultures. Brain Res 1188 (2008) 139-147
16. Kozak W., Conn C.A., and Kluger M.G. Lipopolysaccharide induces fever and depresses locomotor activity in unrestrained mice. Am J Physiol Regul Integr Comp Physiol 266 (1994) R125-R135
17. Laflamme N., and Rivest S. Toll-like receptor 4: the missing link of the cerebral innate immune response triggered by circulating gram-negative bacterial cell wall components. FASEB J 15 1 (2001) 155-163
18. LeBel C.P., Ischiropoulos H., and Bondy S.C. Evaluation of the probe 2,7-dichiorofluorescin as an indicator of reactive oxygen species formation and oxidative stress. Chem Res Toxicol 5 (1992) 227-231
19. Li D.Q., Duan Y.L., Bao Y.M., Liu C.P., Liu Y., and An L.J. Neuroprotection of catalpol in transient global ischemia in gerbils. Neurosci Res 50 (2004) 169-177
20. Li D.Q., Li Y., Liu Y.X., Bao Y.M., Hu B., and An L.J. Catalpol prevents the loss of CA1 hippocampal neurons and reduces working errors in gerbils after ischemia-reperfusion injury. Toxicon 46 (2005) 845-851
21. Liu B., and Hong J.S. Role of microglia in inflammation-mediated neurodegenerative disease: mechanisms and strategies for therapeutic intervention. J Pharmacol Exp Ther 304 (2003) 1-7
22. Mao Y.R., Jiang L., Duan Y.L., and Jiang B. Efficacy of catalpol as protectant against oxidative stress and mitochondrial dysfunction on rotenone-induced toxicity in mice brain. Environ Toxicol Pharmacol 23 (2007) 314-318
23. McGeer P.L., and McGeer E.G. Inflammation, autotoxicity and Alzheimer disease. Neurobiol Aging 22 (2001) 799-809
24. Michael K., and Florian R.G. NF-κB: linking inflammation and immunity to cancer development and progression. Nat Rev Immunol 5 (2005) 749-759
25. Nathan L.S., Rachel A.K., Vincent J.S., and Gary W.B. Bacterial endotoxin-induced behavioral alterations in two variations of the Morris water maze. Physiol Behav 86 (2005) 244-251
26. Nelson P.T., Soma L.A., and Lavi E. Microglia in diseases of the central nervous system. Ann Med 34 (2002) 491-500
27. Orth M., and Schapira A.H. Mitochondrial involvement in Parkinson's disease. Neurochem Int 40 (2002) 533-541
28. Pocock J.M., and Liddle A.C. Microglial signalling cascades in neurodegenerative disease. Prog Brain Res 132 (2001) 555-565
29. Recio M.C., Giner R.M., Manez S., et al. Structural considerations on the iridoids as anti-inflammatory agents. Planta Med 60 3 (1994) 232-234
30. Sharov V.G., Todor A., Khanal S., Imai M., and Sabbah H.N. Cyclosporine A attenuates mitochondrial permeability transition and improves mitochondrial respiratory function in cardiomyocytes isolated from dogs with heart failure. J Mol Cell Cardiol 42 (2007) 150-158
31. Shibata N., Ohnuma T., Takahashi T., Baba H., Ishizuka T., Ohtsuka M., et al. Effect of IL-6 polymorphism on risk of Alzheimer disease: genotype-phenotype association study in Japanese cases. Am J Med Genet 114 4 (2002) 436-439
32. Simon P., John M.L., and Simon J.R.H. Oxidative stress and mitochondrial dysfunction in neurodegeneration; cardiolipin a critical target?. Biochim Biophys Acta 1777 (2008) 794-799
33. Tian Y.Y., An L.J., Jiang L., Duan Y.L., Chen J., and Jiang B. Catalpol protects dopaminergic neurons from LPS induced neurotoxicity in mesencephalic neuron-glia cultures. Life Sci 80 (2006) 193-199
34. Veitch K., Hombroeckx A., Caucheteux D., Pouleur H., and Hue L. Global ischemia induces a biphasic response of the mitochondrial respiratory chain. Anoxic pre-perfusion protects against ischemic damage. Biochem J 281 (1992) 709-715
35. Zamzami N., Marchetti P., Castedo M., Decaudin D., Macho A., Hirsch T., et al. Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death. J Exp Med 182 (1995) 367-377
36. Zhang J., Johnston G., Stebler B., and Keller E.T. Hydrogen peroxide activates NFkappaB and the interleukin-6 promoter through NFkappaB-inducing kinase. Antioxid Redox Signal 3 (2001) 493-504
37. Zhang X.L., Jiang B., Li Z.B., Hao S., and An L.J. Catalpol ameliorates cognition deficits and attenuates oxidative damage in the brain of senescent mice induced by D-galactose. Pharmacol Biochem Behav 88 (2007) 64-72
38. Zhang X.L., Zhang A.H., Jiang B., Bao Y.M., Wang J.Y., and An L.J. Further pharmacological evidence of the neuroprotective effect of catalpol from Rehmannia glutinosa. Phytomedicine 15 (2008) 484-490