메뉴 건너뛰기




Volumn 23, Issue 10, 2014, Pages 1255-1266

Transplantation of human fetal-derived neural stem cells improves cognitive function following cranial irradiation

Author keywords

Cognition; Fear conditioning; Hippocampus; Human fetal derived neural stem cells; Novel place recognition; Radiation; Transplantation

Indexed keywords

DOUBLECORTIN; GLIAL FIBRILLARY ACIDIC PROTEIN; MICROTUBULE ASSOCIATED PROTEIN 2; NESTIN; NEUROFILAMENT PROTEIN; NEURON SPECIFIC NUCLEAR PROTEIN;

EID: 84907970001     PISSN: 09636897     EISSN: 15553892     Source Type: Journal    
DOI: 10.3727/096368913X670200     Document Type: Article
Times cited : (27)

References (64)
  • 1
    • 0036352612 scopus 로고    scopus 로고
    • Pathogenesis of cognitive decline following therapeutic irradiation for head and neck tumors
    • Abayomi, O. K. Pathogenesis of cognitive decline following therapeutic irradiation for head and neck tumors. Acta Oncol. 41(4):346–351; 2002.
    • (2002) Acta Oncol , vol.41 , Issue.4 , pp. 346-351
    • Abayomi, O.K.1
  • 2
    • 10344263377 scopus 로고    scopus 로고
    • Pathogenesis of irradiation-induced cognitive dysfunction
    • Abayomi, O. K. Pathogenesis of irradiation-induced cognitive dysfunction. Acta Oncol. 35(6):659–663; 1996.
    • (1996) Acta Oncol , vol.35 , Issue.6 , pp. 659-663
    • Abayomi, O.K.1
  • 3
    • 73149111251 scopus 로고    scopus 로고
    • Rescue of radiation-induced cognitive impairment through cranial transplantation of human embryonic stem cells
    • Acharya, M. M.; Christie, L. A.; Lan, M. L.; Donovan, P. J.; Cotman, C. W.; Fike, J. R.; Limoli, C. L. Rescue of radiation-induced cognitive impairment through cranial transplantation of human embryonic stem cells. Proc. Natl. Acad. Sci. USA 106(45):19150–19155; 2009.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , Issue.45 , pp. 19150-19155
    • Acharya, M.M.1    Christie, L.A.2    Lan, M.L.3    Donovan, P.J.4    Cotman, C.W.5    Fike, J.R.6    Limoli, C.L.7
  • 4
    • 79960436555 scopus 로고    scopus 로고
    • Human neural stem cell transplantation ameliorates radiation-induced cognitive dysfunction
    • Acharya, M. M.; Christie, L. A.; Lan, M. L.; Giedzinski, E.; Fike, J. R.; Rosi, S.; Limoli, C. L. Human neural stem cell transplantation ameliorates radiation-induced cognitive dysfunction. Cancer Res. 71(14):4834–4845; 2011.
    • (2011) Cancer Res , vol.71 , Issue.14 , pp. 4834-4845
    • Acharya, M.M.1    Christie, L.A.2    Lan, M.L.3    Giedzinski, E.4    Fike, J.R.5    Rosi, S.6    Limoli, C.L.7
  • 5
    • 84873024302 scopus 로고    scopus 로고
    • Comparing the functional consequences of human stem cell transplantation in the irradiated rat brain
    • Acharya, M. M.; Christie, L. A.; Lan, M. L.; Limoli, C. L. Comparing the functional consequences of human stem cell transplantation in the irradiated rat brain. Cell Transplant. 22(1):55–64; 2013.
    • (2013) Cell Transplant , vol.22 , Issue.1 , pp. 55-64
    • Acharya, M.M.1    Christie, L.A.2    Lan, M.L.3    Limoli, C.L.4
  • 6
    • 41149162712 scopus 로고    scopus 로고
    • Progress in neuroprotective strategies for preventing epilepsy
    • Acharya, M. M.; Hattiangady, B.; Shetty, A. K. Progress in neuroprotective strategies for preventing epilepsy. Prog. Neurobiol. 84(4):363–404; 2008.
    • (2008) Prog. Neurobiol , vol.84 , Issue.4 , pp. 363-404
    • Acharya, M.M.1    Hattiangady, B.2    Shetty, A.K.3
  • 7
    • 0028210761 scopus 로고
    • Increased immunoreactivity for Jun- and Fos-related proteins in Alzheimer’s disease: Association with pathology
    • Anderson, A. J.; Cummings, B. J.; Cotman, C. W. Increased immunoreactivity for Jun- and Fos-related proteins in Alzheimer’s disease: Association with pathology. Exp. Neurol. 125(2):286–295; 1994.
    • (1994) Exp. Neurol. , vol.125 , Issue.2 , pp. 286-295
    • Anderson, A.J.1    Cummings, B.J.2    Cotman, C.W.3
  • 11
    • 62949086230 scopus 로고    scopus 로고
    • Engineered adenosine-releasing cells for epilepsy therapy: Human mesenchymal stem cells and human embryonic stem cells
    • Boison, D. Engineered adenosine-releasing cells for epilepsy therapy: Human mesenchymal stem cells and human embryonic stem cells. Neurotherapeutics 6(2):278–283; 2009.
    • (2009) Neurotherapeutics , vol.6 , Issue.2 , pp. 278-283
    • Boison, D.1
  • 13
    • 58149328474 scopus 로고    scopus 로고
    • The immediate early gene arc/arg3.1: Regulation, mechanisms, and function
    • Bramham, C. R.; Worley, P. F.; Moore, M. J.; Guzowski, J. F. The immediate early gene arc/arg3.1: Regulation, mechanisms, and function. J. Neurosci. 28(46):11760–11767; 2008.
    • (2008) J. Neurosci , vol.28 , Issue.46 , pp. 11760-11767
    • Bramham, C.R.1    Worley, P.F.2    Moore, M.J.3    Guzowski, J.F.4
  • 15
    • 33750723795 scopus 로고    scopus 로고
    • Managing the cognitive effects of brain tumor radiation therapy
    • Butler, J. M.; Rapp, S. R.; Shaw, E. G. Managing the cognitive effects of brain tumor radiation therapy. Curr. Treat. Options Oncol. 7(6):517–523; 2006.
    • (2006) Curr. Treat. Options Oncol , vol.7 , Issue.6 , pp. 517-523
    • Butler, J.M.1    Rapp, S.R.2    Shaw, E.G.3
  • 16
    • 63449134691 scopus 로고    scopus 로고
    • Dynamic contrast- enhanced magnetic resonance imaging as a biomarker for prediction of radiation-induced neurocognitive dysfunction. Clin
    • Cao, Y.; Tsien, C. I.; Sundgren, P. C.; Nagesh, V.; Normolle, D.; Buchtel, H.; Junck, L.; Lawrence, T. S. Dynamic contrast- enhanced magnetic resonance imaging as a biomarker for prediction of radiation-induced neurocognitive dysfunction. Clin. Cancer Res. 15(5):1747–1754; 2009.
    • (2009) Cancer Res , vol.15 , Issue.5 , pp. 1747-1754
    • Cao, Y.1    Tsien, C.I.2    Sundgren, P.C.3    Nagesh, V.4    Normolle, D.5    Buchtel, H.6    Junck, L.7    Lawrence, T.S.8
  • 17
    • 84864023887 scopus 로고    scopus 로고
    • Cranial irradiation alters dendritic spine density and morphology in the hippocampus
    • Chakraborti, A.; Allen, A.; Allen, B.; Rosi, S.; Fike, J. R. Cranial irradiation alters dendritic spine density and morphology in the hippocampus. PLoS One 7(7):e40844; 2012.
    • (2012) PLoS One , vol.7 , Issue.7
    • Chakraborti, A.1    Allen, A.2    Allen, B.3    Rosi, S.4    Fike, J.R.5
  • 18
    • 80054945805 scopus 로고    scopus 로고
    • Quantifying cognitive decrements caused by cranial radiotherapy
    • Christie, L. A.; Acharya, M. M.; Limoli, C. L. Quantifying cognitive decrements caused by cranial radiotherapy. J. Vis. Exp. 56:3108; 2011.
    • (2011) J. Vis. Exp , vol.56 , pp. 3108
    • Christie, L.A.1    Acharya, M.M.2    Limoli, C.L.3
  • 20
  • 22
    • 77954667472 scopus 로고    scopus 로고
    • Irradiation of the potential cancer stem cell niches in the adult brain improves progression- free survival of patients with malignant glioma
    • Evers, P.; Lee, P. P.; DeMarco, J.; Agazaryan, N.; Sayre, J. W.; Selch, M.; Pajonk, F. Irradiation of the potential cancer stem cell niches in the adult brain improves progression- free survival of patients with malignant glioma. BMC Cancer 10:384; 2010.
    • (2010) BMC Cancer , vol.10 , pp. 384
    • Evers, P.1    Lee, P.P.2    Demarco, J.3    Agazaryan, N.4    Sayre, J.W.5    Selch, M.6    Pajonk, F.7
  • 23
    • 33846518931 scopus 로고    scopus 로고
    • Radiation response of neural precursor cells
    • Fike, J. R.; Rola, R.; Limoli, C. L. Radiation response of neural precursor cells. Neurosurg. Clin. N. Am. 18(1):115–127; 2007.
    • (2007) Neurosurg. Clin. N. Am , vol.18 , Issue.1 , pp. 115-127
    • Fike, J.R.1    Rola, R.2    Limoli, C.L.3
  • 24
    • 60649107163 scopus 로고    scopus 로고
    • Neural precursor cells and central nervous system radiation sensitivity
    • Fike, J. R.; Rosi, S.; Limoli, C. L. Neural precursor cells and central nervous system radiation sensitivity. Semin. Radiat. Oncol. 19(2):122–132; 2009.
    • (2009) Semin. Radiat. Oncol , vol.19 , Issue.2 , pp. 122-132
    • Fike, J.R.1    Rosi, S.2    Limoli, C.L.3
  • 25
    • 84861919329 scopus 로고    scopus 로고
    • Lumbar intraspinal injection of neural stem cells in patients with amyotrophic lateral sclerosis: Results of a phase I trial in 12 patients
    • Glass, J. D.; Boulis, N. M.; Johe, K.; Rutkove, S. B.; Federici, T.; Polak, M.; Kelly, C.; Feldman, E. L. Lumbar intraspinal injection of neural stem cells in patients with amyotrophic lateral sclerosis: Results of a phase I trial in 12 patients. Stem Cells 30(6):1144–1151; 2012.
    • (2012) Stem Cells , vol.30 , Issue.6 , pp. 1144-1151
    • Glass, J.D.1    Boulis, N.M.2    Johe, K.3    Rutkove, S.B.4    Federici, T.5    Polak, M.6    Kelly, C.7    Feldman, E.L.8
  • 26
    • 0033152450 scopus 로고    scopus 로고
    • Doublecortin is a microtubule-associated protein and is expressed widely by migrating neurons
    • Gleeson, J. G.; Lin, P. T.; Flanagan, L. A.; Walsh, C. A. Doublecortin is a microtubule-associated protein and is expressed widely by migrating neurons. Neuron 23(2):257–271; 1999.
    • (1999) Neuron , vol.23 , Issue.2 , pp. 257-271
    • Gleeson, J.G.1    Lin, P.T.2    Flanagan, L.A.3    Walsh, C.A.4
  • 28
    • 60649108441 scopus 로고    scopus 로고
    • Bone marrow-derived stem cells and radiation response
    • Greenberger, J. S.; Epperly, M. Bone marrow-derived stem cells and radiation response. Semin. Radiat. Oncol. 19(2):133–139; 2009.
    • (2009) Semin. Radiat. Oncol , vol.19 , Issue.2 , pp. 133-139
    • Greenberger, J.S.1    Epperly, M.2
  • 30
    • 77950664250 scopus 로고    scopus 로고
    • Characterization of a human fetal spinal cord stem cell line, NSI-566RSC, and its induction to functional motoneurons
    • Guo, X.; Johe, K.; Molnar, P.; Davis, H.; Hickman, J. Characterization of a human fetal spinal cord stem cell line, NSI-566RSC, and its induction to functional motoneurons. J. Tiss. Eng. Regen. Med. 4(3):181–193; 2010.
    • (2010) J. Tiss. Eng. Regen. Med. , vol.4 , Issue.3 , pp. 181-193
    • Guo, X.1    Johe, K.2    Molnar, P.3    Davis, H.4    Hickman, J.5
  • 31
    • 0033490104 scopus 로고    scopus 로고
    • Environment-specific expression of the immediateearly gene Arc in hippocampal neuronal ensembles
    • Guzowski, J. F.; McNaughton, B. L.; Barnes, C. A.; Worley, P. F. Environment-specific expression of the immediateearly gene Arc in hippocampal neuronal ensembles. Nat. Neurosci. 2(12):1120–1124; 1999.
    • (1999) Nat. Neurosci , vol.2 , Issue.12 , pp. 1120-1124
    • Guzowski, J.F.1    McNaughton, B.L.2    Barnes, C.A.3    Worley, P.F.4
  • 33
    • 84930481981 scopus 로고    scopus 로고
    • Optimization of immunosuppressive therapy for spinal grafting of human spinal stem cells in a rat model of ALS
    • Hefferan, M. P.; Johe, K.; Hazel, T.; Feldman, E. L.; Lunn, J. S.; Marsala, M. Optimization of immunosuppressive therapy for spinal grafting of human spinal stem cells in a rat model of ALS. Cell Transplant. 20(8):1153–1161; 2011.
    • (2011) Cell Transplant , vol.20 , Issue.8 , pp. 1153-1161
    • Hefferan, M.P.1    Johe, K.2    Hazel, T.3    Feldman, E.L.4    Lunn, J.S.5    Marsala, M.6
  • 34
    • 0030448423 scopus 로고    scopus 로고
    • Single factors direct the differentiation of stem cells from the fetal and adult central nervous system
    • Johe, K. K.; Hazel, T. G.; Muller, T.; Dugich-Djordjevic, M. M.; McKay, R. D. Single factors direct the differentiation of stem cells from the fetal and adult central nervous system. Genes Dev. 10(24):3129–3140; 1996.
    • (1996) Genes Dev , vol.10 , Issue.24 , pp. 3129-3140
    • Johe, K.K.1    Hazel, T.G.2    Muller, T.3    Dugich-Djordjevic, M.M.4    McKay, R.D.5
  • 35
    • 48049087707 scopus 로고    scopus 로고
    • Mechanisms of radiation-induced brain toxicity and implications for future clinical trials
    • Kim, J. H.; Brown, S. L.; Jenrow, K. A.; Ryu, S. Mechanisms of radiation-induced brain toxicity and implications for future clinical trials. J. Neurooncol. 87(3):279–286; 2008.
    • (2008) J. Neurooncol , vol.87 , Issue.3 , pp. 279-286
    • Kim, J.H.1    Brown, S.L.2    Jenrow, K.A.3    Ryu, S.4
  • 37
    • 42449125240 scopus 로고    scopus 로고
    • Core neurocognitive functions in children treated for posterior fossa tumors
    • Mabbott, D. J.; Penkman, L.; Witol, A.; Strother, D.; Bouffet, E. Core neurocognitive functions in children treated for posterior fossa tumors. Neuropsychology 22(2):159–168; 2008.
    • (2008) Neuropsychology , vol.22 , Issue.2 , pp. 159-168
    • Mabbott, D.J.1    Penkman, L.2    Witol, A.3    Strother, D.4    Bouffet, E.5
  • 38
    • 62949147663 scopus 로고    scopus 로고
    • Embryonic stem cell-derived neural precursor grafts for treatment of temporal lobe epilepsy
    • Maisano, X.; Carpentino, J.; Becker, S.; Lanza, R.; Aaron, G.; Grabel, L.; Naegele, J. R. Embryonic stem cell-derived neural precursor grafts for treatment of temporal lobe epilepsy. Neurotherapeutics 6(2):263–277; 2009.
    • (2009) Neurotherapeutics , vol.6 , Issue.2 , pp. 263-277
    • Maisano, X.1    Carpentino, J.2    Becker, S.3    Lanza, R.4    Aaron, G.5    Grabel, L.6    Naegele, J.R.7
  • 39
    • 0033628606 scopus 로고    scopus 로고
    • Neurocognitive dysfunction in cancer patients
    • discussion 79, 81–82, 85; 2000
    • Meyers, C. A. Neurocognitive dysfunction in cancer patients. Oncology 14(1):75–79. discussion 79, 81–82, 85; 2000.
    • Oncology , vol.14 , Issue.1 , pp. 75-79
    • Meyers, C.A.1
  • 40
    • 33644870352 scopus 로고    scopus 로고
    • Role and relevance of neurocognitive assessment in clinical trials of patients with CNS tumors
    • Meyers, C. A.; Brown, P. D. Role and relevance of neurocognitive assessment in clinical trials of patients with CNS tumors. J. Clin. Oncol. 24(8):1305–1309; 2006.
    • (2006) J. Clin. Oncol , vol.24 , Issue.8 , pp. 1305-1309
    • Meyers, C.A.1    Brown, P.D.2
  • 41
    • 0033961784 scopus 로고    scopus 로고
    • Neurocognitive effects of therapeutic irradiation for base of skull tumors
    • Meyers, C. A.; Geara, F.; Wong, P. F.; Morrison, W. H. Neurocognitive effects of therapeutic irradiation for base of skull tumors. Int. J. Radiat. Oncol. Biol. Phys. 46(1):51–55. 2000.
    • (2000) Int. J. Radiat. Oncol. Biol. Phys , vol.46 , Issue.1 , pp. 51-55
    • Meyers, C.A.1    Geara, F.2    Wong, P.F.3    Morrison, W.H.4
  • 42
    • 0036283521 scopus 로고    scopus 로고
    • Doublecortin expression in the adult rat telencephalon
    • Nacher, J.; Crespo, C.; McEwen, B. S. Doublecortin expression in the adult rat telencephalon. Eur. J. Neurosci. 14(4):629–644; 2001.
    • (2001) Eur. J. Neurosci , vol.14 , Issue.4 , pp. 629-644
    • Nacher, J.1    Crespo, C.2    McEwen, B.S.3
  • 43
    • 35448958465 scopus 로고    scopus 로고
    • Understanding the cognitive impact on children who are treated for medulloblastoma
    • Palmer, S. L.; Reddick, W. E.; Gajjar, A. Understanding the cognitive impact on children who are treated for medulloblastoma. J. Pediatr. Psychol. 32(9):1040–1049; 2007.
    • (2007) J. Pediatr. Psychol , vol.32 , Issue.9 , pp. 1040-1049
    • Palmer, S.L.1    Reddick, W.E.2    Gajjar, A.3
  • 44
    • 33747354631 scopus 로고    scopus 로고
    • Novel object recognition in Apoe(-/-) mice improved by neonatal implantation of wild-type multipotential stromal cells
    • Peister, A.; Zeitouni, S.; Pfankuch, T.; Reger, R. L.; Prockop, D. J.; Raber, J. Novel object recognition in Apoe(-/-) mice improved by neonatal implantation of wild-type multipotential stromal cells. Exp. Neurol. 201(1):266–269; 2006.
    • (2006) Exp. Neurol , vol.201 , Issue.1 , pp. 266-269
    • Peister, A.1    Zeitouni, S.2    Pfankuch, T.3    Reger, R.L.4    Prockop, D.J.5    Raber, J.6
  • 46
    • 0026635574 scopus 로고
    • Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning
    • Phillips, R. G.; LeDoux, J. E. Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning. Behav. Neurosci. 106(2):274–285; 1992.
    • (1992) Behav. Neurosci , vol.106 , Issue.2 , pp. 274-285
    • Phillips, R.G.1    Ledoux, J.E.2
  • 48
    • 84929237446 scopus 로고    scopus 로고
    • Intraspinal stem cell transplantation in amyotrophic lateral sclerosis: A phase I safety trial, technical note, and lumbar safety outcomes
    • discussion 416; 2012
    • Riley, J.; Federici, T.; Polak, M.; Kelly, C.; Glass, J.; Raore, B.; Taub, J.; Kesner, V.; Feldman, E. L.; Boulis, N. M. Intraspinal stem cell transplantation in amyotrophic lateral sclerosis: A phase I safety trial, technical note, and lumbar safety outcomes. Neurosurgery, 71(2):405–416discussion 416; 2012.
    • Neurosurgery , vol.71 , Issue.2 , pp. 405-416
    • Riley, J.1    Federici, T.2    Polak, M.3    Kelly, C.4    Glass, J.5    Raore, B.6    Taub, J.7    Kesner, V.8    Feldman, E.L.9    Boulis, N.M.10
  • 49
    • 3042799716 scopus 로고    scopus 로고
    • Radiation-induced impairment of hippocampal neurogenesis is associated with cognitive deficits in young mice
    • Rola, R.; Raber, J.; Rizk, A.; Otsuka, S.; VandenBerg, S. R.; Morhardt, D. R.; Fike, J. R. Radiation-induced impairment of hippocampal neurogenesis is associated with cognitive deficits in young mice. Exp. Neurol. 188(2):316–330; 2004.
    • (2004) Exp. Neurol , vol.188 , Issue.2 , pp. 316-330
    • Rola, R.1    Raber, J.2    Rizk, A.3    Otsuka, S.4    Vandenberg, S.R.5    Morhardt, D.R.6    Fike, J.R.7
  • 50
    • 0028914873 scopus 로고
    • Neuropsychological effects of cranial radiation: Current knowledge and future directions
    • Roman, D. D.; Sperduto, P. W. Neuropsychological effects of cranial radiation: Current knowledge and future directions. Int. J. Radiat. Oncol. Biol. Phys. 31(4):983–998. 1995.
    • (1995) Int. J. Radiat. Oncol. Biol. Phys , vol.31 , Issue.4 , pp. 983-998
    • Roman, D.D.1    Sperduto, P.W.2
  • 51
    • 57149094240 scopus 로고    scopus 로고
    • Cranial irradiation alters the behaviorally induced immediate-early gene arc (activityregulated cytoskeleton-associated protein)
    • Rosi, S.; Andres-Mach, M.; Fishman, K. M.; Levy, W.; Ferguson, R. A.; Fike, J. R. Cranial irradiation alters the behaviorally induced immediate-early gene arc (activityregulated cytoskeleton-associated protein). Cancer Res. 68(23):9763–9770; 2008.
    • (2008) Cancer Res , vol.68 , Issue.23 , pp. 9763-9770
    • Rosi, S.1    Andres-Mach, M.2    Fishman, K.M.3    Levy, W.4    Ferguson, R.A.5    Fike, J.R.6
  • 52
    • 78650107542 scopus 로고    scopus 로고
    • Cognitive consequences of the treatment of medulloblastoma among children
    • Saury, J. M.; Emanuelson, I. Cognitive consequences of the treatment of medulloblastoma among children. Pediatr. Neurol. 44(1):21–30; 2011.
    • (2011) Pediatr. Neurol , vol.44 , Issue.1 , pp. 21-30
    • Saury, J.M.1    Emanuelson, I.2
  • 58
    • 33645096734 scopus 로고    scopus 로고
    • Inhibition of neurogenesis interferes with hippocampus-dependent memory function
    • Winocur, G.; Wojtowicz, J. M.; Sekeres, M.; Snyder, J. S.; Wang, S. Inhibition of neurogenesis interferes with hippocampus-dependent memory function. Hippocampus 16(3): 296–304; 2006.
    • (2006) Hippocampus , vol.16 , Issue.3 , pp. 296-304
    • Winocur, G.1    Wojtowicz, J.M.2    Sekeres, M.3    Snyder, J.S.4    Wang, S.5
  • 59
    • 65649090629 scopus 로고    scopus 로고
    • Human neural stem cell grafts in the spinal cord of SOD1 transgenic rats: Differentiation and structural integration into the segmental motor circuitry
    • Xu, L.; Ryugo, D. K.; Pongstaporn, T.; Johe, K.; Koliatsos, V. E. Human neural stem cell grafts in the spinal cord of SOD1 transgenic rats: Differentiation and structural integration into the segmental motor circuitry. J. Comp. Neurol. 514(4):297–309; 2009.
    • (2009) J. Comp. Neurol , vol.514 , Issue.4 , pp. 297-309
    • Xu, L.1    Ryugo, D.K.2    Pongstaporn, T.3    Johe, K.4    Koliatsos, V.E.5
  • 60
    • 33749872454 scopus 로고    scopus 로고
    • Human neural stem cell grafts ameliorate motor neuron disease in SOD-1 transgenic rats
    • Xu, L.; Yan, J.; Chen, D.; Welsh, A. M.; Hazel, T.; Johe, K.; Hatfield, G.; Koliatsos, V. E. Human neural stem cell grafts ameliorate motor neuron disease in SOD-1 transgenic rats. Transplantation 82(7):865–875; 2006.
    • (2006) Transplantation , vol.82 , Issue.7 , pp. 865-875
    • Xu, L.1    Yan, J.2    Chen, D.3    Welsh, A.M.4    Hazel, T.5    Johe, K.6    Hatfield, G.7    Koliatsos, V.E.8
  • 62
    • 33749075049 scopus 로고    scopus 로고
    • Combined immunosuppressive agents or CD4 antibodies prolong survival of human neural stem cell grafts and improve disease outcomes in amyotrophic lateral sclerosis transgenic mice
    • Yan, J.; Xu, L.; Welsh, A. M.; Chen, D.; Hazel, T.; Johe, K.; Koliatsos, V. E. Combined immunosuppressive agents or CD4 antibodies prolong survival of human neural stem cell grafts and improve disease outcomes in amyotrophic lateral sclerosis transgenic mice. Stem Cells 24(8):1976–1985; 2006.
    • (2006) Stem Cells , vol.24 , Issue.8 , pp. 1976-1985
    • Yan, J.1    Xu, L.2    Welsh, A.M.3    Chen, D.4    Hazel, T.5    Johe, K.6    Koliatsos, V.E.7
  • 63
    • 33847663410 scopus 로고    scopus 로고
    • Extensive neuronal differentiation of human neural stem cell grafts in adult rat spinal cord
    • Yan, J.; Xu, L.; Welsh, A. M.; Hatfield, G.; Hazel, T.; Johe, K.; Koliatsos, V. E. Extensive neuronal differentiation of human neural stem cell grafts in adult rat spinal cord. PLoS Med. 4(2):e39; 2007.
    • (2007) PLoS Med , vol.4 , Issue.2
    • Yan, J.1    Xu, L.2    Welsh, A.M.3    Hatfield, G.4    Hazel, T.5    Johe, K.6    Koliatsos, V.E.7
  • 64
    • 84871822928 scopus 로고    scopus 로고
    • Extracellular superoxide dismutase is important for hippocampal neurogenesis and preservation of cognitive functions after irradiation
    • Zou, Y.; Corniola, R.; Leu, D.; Khan, A.; Sahbaie, P.; Chakraborti, A.; Clark, D. J.; Fike, J. R.; Huang, T. T. Extracellular superoxide dismutase is important for hippocampal neurogenesis and preservation of cognitive functions after irradiation. Proc. Natl. Acad. Sci. USA 109(52): 21522–21527; 2012.
    • (2012) Proc. Natl. Acad. Sci. USA , vol.109 , Issue.52 , pp. 21522-21527
    • Zou, Y.1    Corniola, R.2    Leu, D.3    Khan, A.4    Sahbaie, P.5    Chakraborti, A.6    Clark, D.J.7    Fike, J.R.8    Huang, T.T.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.