The VMAT-2 inhibitor tetrabenazine alters effort-related decision making as measured by the T-maze barrier choice task: Reversal with the adenosine A2A antagonist MSX-3 and the catecholamine uptake blocker bupropion

Psychopharmacology

Volumn 232, Issue 7, 2015, Pages 1313-1323

  Yohn, Samantha E ^a   Thompson, Christian ^a   Randall, Patrick A ^a   Lee, Christie A ^a,b   Müller, Christa E ^c   Baqi, Younis ^c,d   Correa, Mercè ^a,e   Salamone, John D ^a  

^a UNIVERSITY OF CONNECTICUT   (United States)

^b NORTH CAROLINA STATE UNIVERSITY   (United States)

^c UNIVERSITY OF BONN   (Germany)

^d SULTAN QABOOS UNIVERSITY   (Oman)

^e UNIVERSITAT JAUME I   (Spain)

Author keywords

Accumbens; Anergia; Behavioral activation; Depression; Dopamine; Fatigue; Motivation; Reward

Indexed keywords

ADENOSINE A2A RECEPTOR ANTAGONIST; AMFEBUTAMONE; PHOSPHORIC ACID MONO[3 [8 [2 (3 METHOXYPHENYL)VINYL] 7 METHYL 2,6 DIOXO 1 PROP 2 YNYL 1,2,6,7 TETRAHYDROPURIN 3 YL]PROPYL]ESTER; TETRABENAZINE; UNCLASSIFIED DRUG; ADENOSINE A2 RECEPTOR ANTAGONIST; ADENOSINE A2A RECEPTOR; ANTIDEPRESSANT AGENT; CATECHOLAMINE; DOPAMINE RECEPTOR BLOCKING AGENT; MSX 3 COMPOUND; SLC18A2 PROTEIN, RAT; VESICULAR MONOAMINE TRANSPORTER; XANTHINE DERIVATIVE;

ADULT; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DECISION MAKING; DRUG ANTAGONISM; DRUG EFFECT; FOOD; LATENT PERIOD; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REINFORCEMENT; REWARD; T MAZE BARRIER CHOICE TASK; TASK PERFORMANCE; ANIMAL; ANTAGONISTS AND INHIBITORS; DOSE RESPONSE; DRUG EFFECTS; MAZE TEST; METABOLISM; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ADENOSINE A2 RECEPTOR ANTAGONISTS; ANIMALS; ANTIDEPRESSIVE AGENTS; BUPROPION; CATECHOLAMINES; CHOICE BEHAVIOR; DECISION MAKING; DOPAMINE ANTAGONISTS; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; MAZE LEARNING; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ADENOSINE A2A; TETRABENAZINE; VESICULAR MONOAMINE TRANSPORT PROTEINS; XANTHINES;

EID: 84924898142     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/s00213-014-3766-0     Document Type: Article

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