Nucleus accumbens adenosine A2A receptors regulate exertion of effort by acting on the ventral striatopallidal pathway

Journal of Neuroscience

Volumn 28, Issue 36, 2008, Pages 9037-9046

  Mingote, Susana ^a,b   Font, Laura ^a,c   Farrar, Andrew M ^a   Vontell, Regina ^a   Worden, Lila T ^a   Stopper, Colin M ^a   Port, Russell G ^a   Sink, Kelly S ^a   Bunce, Jamie G ^a,d   Chrobak, James J ^a   Salamone, John D ^a  

^a UNIVERSITY OF CONNECTICUT   (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

^c UNIVERSITAT JAUME I   (Spain)

^d BOSTON UNIVERSITY   (United States)

Author keywords

Activation; Basal ganglia; Behavioral activation; Depression; Dopamine; Motivation

Indexed keywords

2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); 4 AMINOBUTYRIC ACID A RECEPTOR; ADENOSINE A2 RECEPTOR; MUSCIMOL; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID RECEPTOR STIMULATING AGENT; ADENOSINE; ADENOSINE A2A RECEPTOR; CHOLERA TOXIN; DRUG DERIVATIVE; PHENETHYLAMINE DERIVATIVE; VASOACTIVE INTESTINAL POLYPEPTIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BEHAVIOR; BRAIN NERVE CELL; CONTROLLED STUDY; CORPUS STRIATUM; GLOBUS PALLIDUS; MALE; NERVE CELL NETWORK; NERVE PROJECTION; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; RAT; TASK PERFORMANCE; ANALYSIS OF VARIANCE; ANIMAL; ANIMAL BEHAVIOR; DOSE RESPONSE; DRUG EFFECT; EXERCISE; INSTRUMENTAL CONDITIONING; METABOLISM; NEOSTRIATUM; NERVE TRACT; PHYSIOLOGY; REINFORCEMENT; SPRAGUE DAWLEY RAT;

ADENOSINE; ANALYSIS OF VARIANCE; ANIMALS; BEHAVIOR, ANIMAL; CHOLERA TOXIN; CONDITIONING, OPERANT; DOSE-RESPONSE RELATIONSHIP, DRUG; EXERTION; GABA AGONISTS; GAMMA-AMINOBUTYRIC ACID; GLOBUS PALLIDUS; MALE; MUSCIMOL; NEOSTRIATUM; NEURAL PATHWAYS; NUCLEUS ACCUMBENS; PHENETHYLAMINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ADENOSINE A2A; REINFORCEMENT SCHEDULE; VASOACTIVE INTESTINAL PEPTIDE;

EID: 54049114356     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1525-08.2008     Document Type: Article

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