The dopamine reuptake inhibitor MRZ-9547 increases progressive ratio responding in rats

International Journal of Neuropsychopharmacology

Volumn 17, Issue 12, 2014, Pages 2045-2056

  Sommer, S ^a   Danysz, W ^b   Russ, H ^b   Valastro, B ^b   Flik, G ^c   Hauber, W ^a  

^a UNIVERSITY OF STUTTGART   (Germany)

^b MERZ PHARMACEUTICALS GMBH   (Germany)

^c CHARLES RIVER LABORATORIES   (United States)

Author keywords

Dopamine transporter inhibition; Fatigue; Progressive ratio responding; Rat

Indexed keywords

DOPAMINE UPTAKE INHIBITOR; METHYLPHENIDATE; MRZ 9547; UNCLASSIFIED DRUG; 3,4 DIHYDROXYPHENYLACETIC ACID; BENZHYDRYL DERIVATIVE; CENTRAL STIMULANT AGENT; DEXAMPHETAMINE; DOPAMINE; DOPAMINE TRANSPORTER; MODAFINIL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOPAMINE RELEASE; DRUG BLOOD LEVEL; FATIGUE; HEART FUNCTION; IN VITRO STUDY; IN VIVO STUDY; MAJOR DEPRESSION; MALE; MEDICAL DECISION MAKING; MICRODIALYSIS; NONHUMAN; PARKINSON DISEASE; POST HOC ANALYSIS; PRIORITY JOURNAL; RAT; REINFORCEMENT; TASK PERFORMANCE; ANIMAL; ANTAGONISTS AND INHIBITORS; COMPARATIVE STUDY; CORPUS STRIATUM; DECISION MAKING; DOSE RESPONSE; DRUG EFFECTS; METABOLISM; MOTIVATION; NEUROPSYCHOLOGICAL TEST; SPRAGUE DAWLEY RAT;

3,4-DIHYDROXYPHENYLACETIC ACID; ANIMALS; BENZHYDRYL COMPOUNDS; CENTRAL NERVOUS SYSTEM STIMULANTS; CHOICE BEHAVIOR; CORPUS STRIATUM; DEXTROAMPHETAMINE; DOPAMINE; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; DOPAMINE UPTAKE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; METHYLPHENIDATE; MOTIVATION; NEUROPSYCHOLOGICAL TESTS; RATS, SPRAGUE-DAWLEY; REINFORCEMENT SCHEDULE;

EID: 84938083153     PISSN: 14611457     EISSN: 14695111     Source Type: Journal    
DOI: 10.1017/S1461145714000996     Document Type: Article

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