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Volumn 11, Issue 6, 2015, Pages 4190-4196

Tanshinone IIA attenuates bleomycin-induced pulmonary fibrosis in rats

Author keywords

Bleomycin; Fibrosis; Idiopathic pulmonary fibrosis; Inflammation; Tanshinone IIA

Indexed keywords

CD133 ANTIGEN; MESSENGER RNA; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; PROTEIN BAX; PROTEIN P53; PUMA PROTEIN; RNA; TEMOZOLOMIDE; ABIETANE DERIVATIVE; ANTINEOPLASTIC ANTIBIOTIC; BLEOMYCIN; CYCLOOXYGENASE 2; HERBACEOUS AGENT; INDUCIBLE NITRIC OXIDE SYNTHASE; NITRIC OXIDE; TANSHINONE;

EID: 84924709761     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2015.3333     Document Type: Article
Times cited : (54)

References (46)
  • 1
    • 60649102339 scopus 로고    scopus 로고
    • Pulmonary fibrosis: Pathogenesis, etiology and regulation
    • Wilson MS and Wynn TA: Pulmonary fibrosis: pathogenesis, etiology and regulation. Mucosal Immunol 2: 103-121, 2009.
    • (2009) Mucosal Immunol , vol.2 , pp. 103-121
    • Wilson, M.S.1    Wynn, T.A.2
  • 2
    • 75949130829 scopus 로고    scopus 로고
    • Strategies for treating idiopathic pulmonary fibrosis
    • du Bois RM: Strategies for treating idiopathic pulmonary fibrosis. Nat Rev Drug Discov 9: 129-140, 2010.
    • (2010) Nat Rev Drug Discov , vol.9 , pp. 129-140
    • Du Bois, R.M.1
  • 3
    • 84863702343 scopus 로고    scopus 로고
    • Mechanisms of fibrosis: Therapeutic translation for fibrotic disease
    • Wynn TA and Ramalingam TR: Mechanisms of fibrosis: therapeutic translation for fibrotic disease. Nat Med 18: 1028-1040, 2012.
    • (2012) Nat Med , vol.18 , pp. 1028-1040
    • Wynn, T.A.1    Ramalingam, T.R.2
  • 4
    • 37549060626 scopus 로고    scopus 로고
    • The role of inflammation in the pathogenesis of idiopathic pulmonary fibrosis
    • Bringardner BD, Baran CP, Eubank TD and Marsh CB: The role of inflammation in the pathogenesis of idiopathic pulmonary fibrosis. Antioxid Redox Signal 10: 287-301, 2008.
    • (2008) Antioxid Redox Signal , vol.10 , pp. 287-301
    • Bringardner, B.D.1    Baran, C.P.2    Eubank, T.D.3    Marsh, C.B.4
  • 5
    • 77955092333 scopus 로고    scopus 로고
    • Oxidative stress, extracellular matrix targets, and idiopathic pulmonary fibrosis
    • Kliment CR and Oury TD: Oxidative stress, extracellular matrix targets, and idiopathic pulmonary fibrosis. Free Radic Biol Med 49: 707-717, 2010.
    • (2010) Free Radic Biol Med , vol.49 , pp. 707-717
    • Kliment, C.R.1    Oury, T.D.2
  • 6
    • 0038359740 scopus 로고    scopus 로고
    • Reactive oxygen species (ROS) and reactive nitrogen species (RNS) generation by silica in inflammation and fibrosis
    • Fubini B and Hubbard A: Reactive oxygen species (ROS) and reactive nitrogen species (RNS) generation by silica in inflammation and fibrosis. Free Radic Biol Med 34: 1507-1516, 2003.
    • (2003) Free Radic Biol Med , vol.34 , pp. 1507-1516
    • Fubini, B.1    Hubbard, A.2
  • 7
    • 58149343403 scopus 로고    scopus 로고
    • Regulatory watch: First drug for idiopathic pulmonary fibrosis approved in Japan
    • No authors listed: Regulatory watch: First drug for idiopathic pulmonary fibrosis approved in Japan. Nat Rev Drug Discov 7: 966-967, 2008.
    • (2008) Nat Rev Drug Discov , vol.7 , pp. 966-967
    • Authors Listed, N.1
  • 8
    • 79961105470 scopus 로고    scopus 로고
    • P38 kinase inhibitor approved for idiopathic pulmonary fibrosis
    • Moran N: p38 kinase inhibitor approved for idiopathic pulmonary fibrosis. Nat Biotechnol 29: 301, 2011.
    • (2011) Nat Biotechnol , vol.29 , pp. 301
    • Moran, N.1
  • 9
    • 27844511101 scopus 로고    scopus 로고
    • Danshen: An overview of its chemistry, pharmacology, pharmacokinetics and clinical use
    • Zhou L, Zuo Z and Chow MS: Danshen: an overview of its chemistry, pharmacology, pharmacokinetics and clinical use. J Clin Pharmacol 45: 1345-1359, 2005.
    • (2005) J Clin Pharmacol , vol.45 , pp. 1345-1359
    • Zhou, L.1    Zuo, Z.2    Chow, M.S.3
  • 10
    • 84887617944 scopus 로고    scopus 로고
    • Tanshinone IIA inhibits human prostate cancer cells growth by induction of endoplasmic reticulum stress in vitro and in vivo
    • Chiu SC, Huang SY, Chen SP, Su CC, Chiu TL and Pang CY: Tanshinone IIA inhibits human prostate cancer cells growth by induction of endoplasmic reticulum stress in vitro and in vivo. Prostate Cancer Prostatic Dis 16: 315-322, 2013.
    • (2013) Prostate Cancer Prostatic Dis , vol.16 , pp. 315-322
    • Chiu, S.C.1    Huang, S.Y.2    Chen, S.P.3    Su, C.C.4    Chiu, T.L.5    Pang, C.Y.6
  • 11
    • 70449339753 scopus 로고    scopus 로고
    • Inhibitory effects of tanshinone II-A on invasion and metastasis of human colon carcinoma cells
    • Shan YF, Shen X, Xie YK, et al: Inhibitory effects of tanshinone II-A on invasion and metastasis of human colon carcinoma cells. Acta Pharmacol Sin 30: 1537-1542, 2009.
    • (2009) Acta Pharmacol Sin , vol.30 , pp. 1537-1542
    • Shan, Y.F.1    Shen, X.2    Xie, Y.K.3
  • 12
    • 84894610439 scopus 로고    scopus 로고
    • A novel anti-cancer agent, acetyltanshinone IIA, inhibits oestrogen receptor positive breast cancer cell growth by down-regulating the oestrogen receptor
    • Yu T, Zhou Z, Mu Y, de Lima Lopes G and Luo KQ: A novel anti-cancer agent, acetyltanshinone IIA, inhibits oestrogen receptor positive breast cancer cell growth by down-regulating the oestrogen receptor. Cancer Lett 346: 94-103, 2014.
    • (2014) Cancer Lett , vol.346 , pp. 94-103
    • Yu, T.1    Zhou, Z.2    Mu, Y.3    De Lima Lopes, G.4    Luo, K.Q.5
  • 13
    • 78649968738 scopus 로고    scopus 로고
    • Tanshinone IIA attenuates angiotensin II-induced apoptosis via Akt pathway in neonatal rat cardiomyocytes
    • Hong HJ, Liu JC, Cheng TH and Chan P: Tanshinone IIA attenuates angiotensin II-induced apoptosis via Akt pathway in neonatal rat cardiomyocytes. Acta Pharmacol Sin 31: 1569-1575, 2010.
    • (2010) Acta Pharmacol Sin , vol.31 , pp. 1569-1575
    • Hong, H.J.1    Liu, J.C.2    Cheng, T.H.3    Chan, P.4
  • 14
    • 84155164808 scopus 로고    scopus 로고
    • Cardiovascular actions and therapeutic potential of tanshinone IIA
    • Gao S, Liu Z, Li H, Little PJ, Liu P and Xu S: Cardiovascular actions and therapeutic potential of tanshinone IIA. Atherosclerosis 220: 3-10, 2012.
    • (2012) Atherosclerosis , vol.220 , pp. 3-10
    • Gao, S.1    Liu, Z.2    Li, H.3    Little, P.J.4    Liu, P.5    Xu, S.6
  • 15
    • 84863090435 scopus 로고    scopus 로고
    • Neuroprotection of tanshinone IIA against cerebral ischemia/reperfusion injury through inhibition of macrophage migration inhibitory factor in rats
    • Chen Y, Wu X, Yu S, et al: Neuroprotection of tanshinone IIA against cerebral ischemia/reperfusion injury through inhibition of macrophage migration inhibitory factor in rats. PLoS One 7: e40165, 2012.
    • (2012) PLoS One , vol.7 , pp. e40165
    • Chen, Y.1    Wu, X.2    Yu, S.3
  • 16
    • 1542755400 scopus 로고    scopus 로고
    • Effect of tanshinone IIA on CCl4-induced liver fibrosis in rats
    • (In Chinese)
    • Liu Y, Chen H and Jiang Y: Effect of tanshinone IIA on CCl4-induced liver fibrosis in rats. Zhong Yao Cai 25: 31-33, 2002 (In Chinese).
    • (2002) Zhong Yao Cai , vol.25 , pp. 31-33
    • Liu, Y.1    Chen, H.2    Jiang, Y.3
  • 18
    • 79952674320 scopus 로고    scopus 로고
    • Tanshinone IIA attenuates peritoneal fibrosis through inhibition of fibrogenic growth factors expression in peritoneum in a peritoneal dialysis rat model
    • (In Chinese)
    • Chunming J, Miao Z, Cheng S, et al: Tanshinone IIA attenuates peritoneal fibrosis through inhibition of fibrogenic growth factors expression in peritoneum in a peritoneal dialysis rat model. Ren Fail 33: 355-362, 2011 (In Chinese).
    • (2011) Ren Fail , vol.33 , pp. 355-362
    • Chunming, J.1    Miao, Z.2    Cheng, S.3
  • 20
    • 34347364932 scopus 로고    scopus 로고
    • Detection of epithelial to mesenchymal transition in airways of a bleomycin induced pulmonary fibrosis model derived from an alpha-smooth muscle actin-Cre transgenic mouse
    • Wu Z, Yang L, Cai L, et al: Detection of epithelial to mesenchymal transition in airways of a bleomycin induced pulmonary fibrosis model derived from an alpha-smooth muscle actin-Cre transgenic mouse. Respir Res 8: 1, 2007.
    • (2007) Respir Res , vol.8 , pp. 1
    • Wu, Z.1    Yang, L.2    Cai, L.3
  • 21
    • 0023914820 scopus 로고
    • Simple method of estimating severity of pulmonary fibrosis on a numerical scale
    • Ashcroft T, Simpson JM and Timbrell V: Simple method of estimating severity of pulmonary fibrosis on a numerical scale. J Clin Pathol 41: 467-470, 1988.
    • (1988) J Clin Pathol , vol.41 , pp. 467-470
    • Ashcroft, T.1    Simpson, J.M.2    Timbrell, V.3
  • 22
    • 44449122824 scopus 로고    scopus 로고
    • Standardized quantification of pulmonary fibrosis in histological samples
    • 514-507
    • Hübner RH, Gitter W, El Mokhtari NE, et al: Standardized quantification of pulmonary fibrosis in histological samples. Biotechniques 44: 507-511, 514-507, 2008.
    • (2008) Biotechniques , vol.44 , pp. 507-511
    • Hübner, R.H.1    Gitter, W.2    El Mokhtari, N.E.3
  • 23
    • 33745001237 scopus 로고    scopus 로고
    • Elevated serum nitric oxide and superoxide dismutase in euthymic bipolar patients: Impact of past episodes
    • Savas HA, Gergerlioglu HS, Armutcu F, et al: Elevated serum nitric oxide and superoxide dismutase in euthymic bipolar patients: impact of past episodes. World J Biol Psychiatry 7: 51-55, 2006.
    • (2006) World J Biol Psychiatry , vol.7 , pp. 51-55
    • Savas, H.A.1    Gergerlioglu, H.S.2    Armutcu, F.3
  • 26
    • 62349138124 scopus 로고    scopus 로고
    • The COX-2/PGE2 pathway: Key roles in the hallmarks of cancer and adaptation to the tumour microenvironment
    • Greenhough A, Smartt HJ, Moore AE, et al: The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment. Carcinogenesis 30: 377-386, 2009.
    • (2009) Carcinogenesis , vol.30 , pp. 377-386
    • Greenhough, A.1    Smartt, H.J.2    Moore, A.E.3
  • 27
    • 18444385685 scopus 로고    scopus 로고
    • Malondialdehyde (MDA) as a lipid peroxidation marker
    • (In Polish)
    • Gawel S, Wardas M, Niedworok E and Wardas P: Malondialdehyde (MDA) as a lipid peroxidation marker. Wiad Lek 57: 453-455, 2004 (In Polish).
    • (2004) Wiad Lek , vol.57 , pp. 453-455
    • Gawel, S.1    Wardas, M.2    Niedworok, E.3    Wardas, P.4
  • 28
    • 84863291618 scopus 로고    scopus 로고
    • Oxymatrine attenuates bleomycin-induced pulmonary fibrosis in mice via the inhibition of inducible nitric oxide synthase expression and the TGF-/Smad signaling pathway
    • Liu L, Lu W, Ma Z and Li Z: Oxymatrine attenuates bleomycin-induced pulmonary fibrosis in mice via the inhibition of inducible nitric oxide synthase expression and the TGF-/Smad signaling pathway. Int J Mol Med 29: 815-822, 2012.
    • (2012) Int J Mol Med , vol.29 , pp. 815-822
    • Liu, L.1    Lu, W.2    Ma, Z.3    Li, Z.4
  • 29
    • 77954734117 scopus 로고    scopus 로고
    • Inhibitory effect of CXC chemokine receptor 4 antagonist AMD3100 on bleomycin induced murine pulmonary fibrosis
    • Song JS, Kang CM, Kang HH, et al: Inhibitory effect of CXC chemokine receptor 4 antagonist AMD3100 on bleomycin induced murine pulmonary fibrosis. Exp Mol Med 42: 465-472, 2010.
    • (2010) Exp Mol Med , vol.42 , pp. 465-472
    • Song, J.S.1    Kang, C.M.2    Kang, H.H.3
  • 30
    • 84879682510 scopus 로고    scopus 로고
    • Sorafenib ameliorates bleomycin-induced pulmonary fibrosis: Potential roles in the inhibition of epithelial-mesenchymal transition and fibroblast activation
    • Chen YL, Zhang X, Bai J, et al: Sorafenib ameliorates bleomycin-induced pulmonary fibrosis: potential roles in the inhibition of epithelial-mesenchymal transition and fibroblast activation. Cell Death Dis 4: e665, 2013.
    • (2013) Cell Death Dis , vol.4 , pp. e665
    • Chen, Y.L.1    Zhang, X.2    Bai, J.3
  • 31
    • 73649142077 scopus 로고    scopus 로고
    • Anti-inflammatory effects of tanshinone IIA on radiation-induced microglia BV-2 cells inflammatory response
    • Dong X, Dong J, Zhang R, Fan L, Liu L and Wu G: Anti-inflammatory effects of tanshinone IIA on radiation-induced microglia BV-2 cells inflammatory response. Cancer Biother Radiopharm 24: 681-687, 2009.
    • (2009) Cancer Biother Radiopharm , vol.24 , pp. 681-687
    • Dong, X.1    Dong, J.2    Zhang, R.3    Fan, L.4    Liu, L.5    Wu, G.6
  • 32
    • 61349154148 scopus 로고    scopus 로고
    • The anti-inflammatory activities of Tanshinone IIA, an active component of TCM, are mediated by estrogen receptor activation and inhibition of iNOS
    • Fan GW, Gao XM, Wang H, et al: The anti-inflammatory activities of Tanshinone IIA, an active component of TCM, are mediated by estrogen receptor activation and inhibition of iNOS. J Steroid Biochem Mol Biol 113: 275-280, 2009.
    • (2009) J Steroid Biochem Mol Biol , vol.113 , pp. 275-280
    • Fan, G.W.1    Gao, X.M.2    Wang, H.3
  • 33
    • 78649789528 scopus 로고    scopus 로고
    • Tanshinone II-A attenuates cardiac fibrosis and modulates collagen metabolism in rats with renovascular hypertension
    • Fang J, Xu SW, Wang P, et al: Tanshinone II-A attenuates cardiac fibrosis and modulates collagen metabolism in rats with renovascular hypertension. Phytomedicine 18: 58-64, 2010.
    • (2010) Phytomedicine , vol.18 , pp. 58-64
    • Fang, J.1    Xu, S.W.2    Wang, P.3
  • 34
    • 23644461803 scopus 로고    scopus 로고
    • Oxidative stress in pulmonary fibrosis: A possible role for redox modulatory therapy
    • Kinnula VL, Fattman CL, Tan RJ and Oury TD: Oxidative stress in pulmonary fibrosis: a possible role for redox modulatory therapy. Am J Respir Crit Care Med 172: 417-422, 2005.
    • (2005) Am J Respir Crit Care Med , vol.172 , pp. 417-422
    • Kinnula, V.L.1    Fattman, C.L.2    Tan, R.J.3    Oury, T.D.4
  • 36
    • 79953661402 scopus 로고    scopus 로고
    • Tanshinone IIA inhibits angiotensin II-induced cell proliferation in rat cardiac fibroblasts
    • Chan P, Liu JC, Lin LJ, et al: Tanshinone IIA inhibits angiotensin II-induced cell proliferation in rat cardiac fibroblasts. Am J Chin Med 39: 381-394, 2011.
    • (2011) Am J Chin Med , vol.39 , pp. 381-394
    • Chan, P.1    Liu, J.C.2    Lin, L.J.3
  • 37
    • 84862971779 scopus 로고    scopus 로고
    • Protective effect of tanshinone IIA on rat kidneys during hypothermic preservation
    • Zhang X, He D, Xu L and Ling S: Protective effect of tanshinone IIA on rat kidneys during hypothermic preservation. Mol Med Rep 5: 405-409, 2012.
    • (2012) Mol Med Rep , vol.5 , pp. 405-409
    • Zhang, X.1    He, D.2    Xu, L.3    Ling, S.4
  • 38
    • 73649126883 scopus 로고    scopus 로고
    • Tanshinone IIA induces apoptosis in human lung cancer A549 cells through the induction of reactive oxygen species and decreasing the mitochondrial membrane potential
    • Chiu TL and Su CC: Tanshinone IIA induces apoptosis in human lung cancer A549 cells through the induction of reactive oxygen species and decreasing the mitochondrial membrane potential. Int J Mol Med 25: 231-236, 2010.
    • (2010) Int J Mol Med , vol.25 , pp. 231-236
    • Chiu, T.L.1    Su, C.C.2
  • 39
    • 0030838509 scopus 로고    scopus 로고
    • Plasma malondialdehyde as biomarker for oxidative stress: Reference interval and effects of life-style factors
    • Nielsen F, Mikkelsen BB, Nielsen JB, Andersen HR and Grandjean P: Plasma malondialdehyde as biomarker for oxidative stress: reference interval and effects of life-style factors. Clin Chem 43: 1209-1214, 1997.
    • (1997) Clin Chem , vol.43 , pp. 1209-1214
    • Nielsen, F.1    Mikkelsen, B.B.2    Nielsen, J.B.3    Andersen, H.R.4    Grandjean, P.5
  • 40
    • 45749101298 scopus 로고    scopus 로고
    • Inhibition of prostaglandin and nitric oxide production in lipopolysaccharide-treated RAW 264. 7 cells by tanshinones from the roots of Salvia miltiorrhiza bunge
    • Jeon SJ, Son KH, Kim YS, Choi YH and Kim HP: Inhibition of prostaglandin and nitric oxide production in lipopolysaccharide-treated RAW 264.7 cells by tanshinones from the roots of Salvia miltiorrhiza bunge. Arch Pharm Res 31: 758-763, 2008.
    • (2008) Arch Pharm Res , vol.31 , pp. 758-763
    • Jeon, S.J.1    Son, K.H.2    Kim, Y.S.3    Choi, Y.H.4    Kim, H.P.5
  • 41
    • 78651333298 scopus 로고    scopus 로고
    • Cardioprotective effects of tanshinone IIA pretreatment via kinin B2 receptor-Akt-GSK-3beta dependent pathway in experimental diabetic cardiomyopathy
    • Sun D, Shen M, Li J, et al: Cardioprotective effects of tanshinone IIA pretreatment via kinin B2 receptor-Akt-GSK-3beta dependent pathway in experimental diabetic cardiomyopathy. Cardiovasc Diabetol 10: 4, 2011.
    • (2011) Cardiovasc Diabetol , vol.10 , pp. 4
    • Sun, D.1    Shen, M.2    Li, J.3
  • 42
    • 65649128507 scopus 로고    scopus 로고
    • Neuroprotective effects of Tanshinone IIA on permanent focal cerebral ischemia in mice
    • Dong K, Xu W, Yang J, Qiao H and Wu L: Neuroprotective effects of Tanshinone IIA on permanent focal cerebral ischemia in mice. Phytother Res 23: 608-613, 2009.
    • (2009) Phytother Res , vol.23 , pp. 608-613
    • Dong, K.1    Xu, W.2    Yang, J.3    Qiao, H.4    Wu, L.5
  • 43
    • 33846850150 scopus 로고    scopus 로고
    • Nitric oxide in the pathogenesis of diffuse pulmonary fibrosis
    • Hsu YC, Wang LF and Chien YW: Nitric oxide in the pathogenesis of diffuse pulmonary fibrosis. Free Radic Biol Med 42: 599-607, 2007.
    • (2007) Free Radic Biol Med , vol.42 , pp. 599-607
    • Hsu, Y.C.1    Wang, L.F.2    Chien, Y.W.3
  • 44
    • 26244464290 scopus 로고    scopus 로고
    • Inhibition or knock out of inducible nitric oxide synthase result in resistance to bleomycin-induced lung injury
    • Genovese T, Cuzzocrea S, Di Paola R, et al: Inhibition or knock out of inducible nitric oxide synthase result in resistance to bleomycin-induced lung injury. Respir Res 6: 58, 2005.
    • (2005) Respir Res , vol.6 , pp. 58
    • Genovese, T.1    Cuzzocrea, S.2    Di Paola, R.3
  • 45
    • 33847684809 scopus 로고    scopus 로고
    • Tanshinone IIA from Salvia miltiorrhiza induces heme oxygenase-1 expression and inhibits lipopolysaccharide-induced nitric oxide expression in RAW 264
    • Chen TH, Hsu YT, Chen CH, Kao SH and Lee HM: Tanshinone IIA from Salvia miltiorrhiza induces heme oxygenase-1 expression and inhibits lipopolysaccharide-induced nitric oxide expression in RAW 264.7 cells. Mitochondrion 7: 101-105, 2007.
    • (2007) 7 Cells. Mitochondrion , vol.7 , pp. 101-105
    • Chen, T.H.1    Hsu, Y.T.2    Chen, C.H.3    Kao, S.H.4    Lee, H.M.5
  • 46
    • 0345707647 scopus 로고    scopus 로고
    • Regulatory effects of iNOS on acute lung inflammatory responses in mice
    • Speyer CL, Neff TA, Warner RL, et al: Regulatory effects of iNOS on acute lung inflammatory responses in mice. Am J Pathol 163: 2319-2328, 2003.
    • (2003) Am J Pathol , vol.163 , pp. 2319-2328
    • Speyer, C.L.1    Neff, T.A.2    Warner, R.L.3


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