-
1
-
-
60649102339
-
Pulmonary fibrosis: Pathogenesis, etiology and regulation
-
Wilson MS and Wynn TA: Pulmonary fibrosis: pathogenesis, etiology and regulation. Mucosal Immunol 2: 103-121, 2009.
-
(2009)
Mucosal Immunol
, vol.2
, pp. 103-121
-
-
Wilson, M.S.1
Wynn, T.A.2
-
2
-
-
75949130829
-
Strategies for treating idiopathic pulmonary fibrosis
-
du Bois RM: Strategies for treating idiopathic pulmonary fibrosis. Nat Rev Drug Discov 9: 129-140, 2010.
-
(2010)
Nat Rev Drug Discov
, vol.9
, pp. 129-140
-
-
Du Bois, R.M.1
-
3
-
-
84863702343
-
Mechanisms of fibrosis: Therapeutic translation for fibrotic disease
-
Wynn TA and Ramalingam TR: Mechanisms of fibrosis: therapeutic translation for fibrotic disease. Nat Med 18: 1028-1040, 2012.
-
(2012)
Nat Med
, vol.18
, pp. 1028-1040
-
-
Wynn, T.A.1
Ramalingam, T.R.2
-
5
-
-
77955092333
-
Oxidative stress, extracellular matrix targets, and idiopathic pulmonary fibrosis
-
Kliment CR and Oury TD: Oxidative stress, extracellular matrix targets, and idiopathic pulmonary fibrosis. Free Radic Biol Med 49: 707-717, 2010.
-
(2010)
Free Radic Biol Med
, vol.49
, pp. 707-717
-
-
Kliment, C.R.1
Oury, T.D.2
-
6
-
-
0038359740
-
Reactive oxygen species (ROS) and reactive nitrogen species (RNS) generation by silica in inflammation and fibrosis
-
Fubini B and Hubbard A: Reactive oxygen species (ROS) and reactive nitrogen species (RNS) generation by silica in inflammation and fibrosis. Free Radic Biol Med 34: 1507-1516, 2003.
-
(2003)
Free Radic Biol Med
, vol.34
, pp. 1507-1516
-
-
Fubini, B.1
Hubbard, A.2
-
7
-
-
58149343403
-
Regulatory watch: First drug for idiopathic pulmonary fibrosis approved in Japan
-
No authors listed: Regulatory watch: First drug for idiopathic pulmonary fibrosis approved in Japan. Nat Rev Drug Discov 7: 966-967, 2008.
-
(2008)
Nat Rev Drug Discov
, vol.7
, pp. 966-967
-
-
Authors Listed, N.1
-
8
-
-
79961105470
-
P38 kinase inhibitor approved for idiopathic pulmonary fibrosis
-
Moran N: p38 kinase inhibitor approved for idiopathic pulmonary fibrosis. Nat Biotechnol 29: 301, 2011.
-
(2011)
Nat Biotechnol
, vol.29
, pp. 301
-
-
Moran, N.1
-
9
-
-
27844511101
-
Danshen: An overview of its chemistry, pharmacology, pharmacokinetics and clinical use
-
Zhou L, Zuo Z and Chow MS: Danshen: an overview of its chemistry, pharmacology, pharmacokinetics and clinical use. J Clin Pharmacol 45: 1345-1359, 2005.
-
(2005)
J Clin Pharmacol
, vol.45
, pp. 1345-1359
-
-
Zhou, L.1
Zuo, Z.2
Chow, M.S.3
-
10
-
-
84887617944
-
Tanshinone IIA inhibits human prostate cancer cells growth by induction of endoplasmic reticulum stress in vitro and in vivo
-
Chiu SC, Huang SY, Chen SP, Su CC, Chiu TL and Pang CY: Tanshinone IIA inhibits human prostate cancer cells growth by induction of endoplasmic reticulum stress in vitro and in vivo. Prostate Cancer Prostatic Dis 16: 315-322, 2013.
-
(2013)
Prostate Cancer Prostatic Dis
, vol.16
, pp. 315-322
-
-
Chiu, S.C.1
Huang, S.Y.2
Chen, S.P.3
Su, C.C.4
Chiu, T.L.5
Pang, C.Y.6
-
11
-
-
70449339753
-
Inhibitory effects of tanshinone II-A on invasion and metastasis of human colon carcinoma cells
-
Shan YF, Shen X, Xie YK, et al: Inhibitory effects of tanshinone II-A on invasion and metastasis of human colon carcinoma cells. Acta Pharmacol Sin 30: 1537-1542, 2009.
-
(2009)
Acta Pharmacol Sin
, vol.30
, pp. 1537-1542
-
-
Shan, Y.F.1
Shen, X.2
Xie, Y.K.3
-
12
-
-
84894610439
-
A novel anti-cancer agent, acetyltanshinone IIA, inhibits oestrogen receptor positive breast cancer cell growth by down-regulating the oestrogen receptor
-
Yu T, Zhou Z, Mu Y, de Lima Lopes G and Luo KQ: A novel anti-cancer agent, acetyltanshinone IIA, inhibits oestrogen receptor positive breast cancer cell growth by down-regulating the oestrogen receptor. Cancer Lett 346: 94-103, 2014.
-
(2014)
Cancer Lett
, vol.346
, pp. 94-103
-
-
Yu, T.1
Zhou, Z.2
Mu, Y.3
De Lima Lopes, G.4
Luo, K.Q.5
-
13
-
-
78649968738
-
Tanshinone IIA attenuates angiotensin II-induced apoptosis via Akt pathway in neonatal rat cardiomyocytes
-
Hong HJ, Liu JC, Cheng TH and Chan P: Tanshinone IIA attenuates angiotensin II-induced apoptosis via Akt pathway in neonatal rat cardiomyocytes. Acta Pharmacol Sin 31: 1569-1575, 2010.
-
(2010)
Acta Pharmacol Sin
, vol.31
, pp. 1569-1575
-
-
Hong, H.J.1
Liu, J.C.2
Cheng, T.H.3
Chan, P.4
-
14
-
-
84155164808
-
Cardiovascular actions and therapeutic potential of tanshinone IIA
-
Gao S, Liu Z, Li H, Little PJ, Liu P and Xu S: Cardiovascular actions and therapeutic potential of tanshinone IIA. Atherosclerosis 220: 3-10, 2012.
-
(2012)
Atherosclerosis
, vol.220
, pp. 3-10
-
-
Gao, S.1
Liu, Z.2
Li, H.3
Little, P.J.4
Liu, P.5
Xu, S.6
-
15
-
-
84863090435
-
Neuroprotection of tanshinone IIA against cerebral ischemia/reperfusion injury through inhibition of macrophage migration inhibitory factor in rats
-
Chen Y, Wu X, Yu S, et al: Neuroprotection of tanshinone IIA against cerebral ischemia/reperfusion injury through inhibition of macrophage migration inhibitory factor in rats. PLoS One 7: e40165, 2012.
-
(2012)
PLoS One
, vol.7
, pp. e40165
-
-
Chen, Y.1
Wu, X.2
Yu, S.3
-
16
-
-
1542755400
-
Effect of tanshinone IIA on CCl4-induced liver fibrosis in rats
-
(In Chinese)
-
Liu Y, Chen H and Jiang Y: Effect of tanshinone IIA on CCl4-induced liver fibrosis in rats. Zhong Yao Cai 25: 31-33, 2002 (In Chinese).
-
(2002)
Zhong Yao Cai
, vol.25
, pp. 31-33
-
-
Liu, Y.1
Chen, H.2
Jiang, Y.3
-
18
-
-
79952674320
-
Tanshinone IIA attenuates peritoneal fibrosis through inhibition of fibrogenic growth factors expression in peritoneum in a peritoneal dialysis rat model
-
(In Chinese)
-
Chunming J, Miao Z, Cheng S, et al: Tanshinone IIA attenuates peritoneal fibrosis through inhibition of fibrogenic growth factors expression in peritoneum in a peritoneal dialysis rat model. Ren Fail 33: 355-362, 2011 (In Chinese).
-
(2011)
Ren Fail
, vol.33
, pp. 355-362
-
-
Chunming, J.1
Miao, Z.2
Cheng, S.3
-
20
-
-
34347364932
-
Detection of epithelial to mesenchymal transition in airways of a bleomycin induced pulmonary fibrosis model derived from an alpha-smooth muscle actin-Cre transgenic mouse
-
Wu Z, Yang L, Cai L, et al: Detection of epithelial to mesenchymal transition in airways of a bleomycin induced pulmonary fibrosis model derived from an alpha-smooth muscle actin-Cre transgenic mouse. Respir Res 8: 1, 2007.
-
(2007)
Respir Res
, vol.8
, pp. 1
-
-
Wu, Z.1
Yang, L.2
Cai, L.3
-
21
-
-
0023914820
-
Simple method of estimating severity of pulmonary fibrosis on a numerical scale
-
Ashcroft T, Simpson JM and Timbrell V: Simple method of estimating severity of pulmonary fibrosis on a numerical scale. J Clin Pathol 41: 467-470, 1988.
-
(1988)
J Clin Pathol
, vol.41
, pp. 467-470
-
-
Ashcroft, T.1
Simpson, J.M.2
Timbrell, V.3
-
22
-
-
44449122824
-
Standardized quantification of pulmonary fibrosis in histological samples
-
514-507
-
Hübner RH, Gitter W, El Mokhtari NE, et al: Standardized quantification of pulmonary fibrosis in histological samples. Biotechniques 44: 507-511, 514-507, 2008.
-
(2008)
Biotechniques
, vol.44
, pp. 507-511
-
-
Hübner, R.H.1
Gitter, W.2
El Mokhtari, N.E.3
-
23
-
-
33745001237
-
Elevated serum nitric oxide and superoxide dismutase in euthymic bipolar patients: Impact of past episodes
-
Savas HA, Gergerlioglu HS, Armutcu F, et al: Elevated serum nitric oxide and superoxide dismutase in euthymic bipolar patients: impact of past episodes. World J Biol Psychiatry 7: 51-55, 2006.
-
(2006)
World J Biol Psychiatry
, vol.7
, pp. 51-55
-
-
Savas, H.A.1
Gergerlioglu, H.S.2
Armutcu, F.3
-
26
-
-
62349138124
-
The COX-2/PGE2 pathway: Key roles in the hallmarks of cancer and adaptation to the tumour microenvironment
-
Greenhough A, Smartt HJ, Moore AE, et al: The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment. Carcinogenesis 30: 377-386, 2009.
-
(2009)
Carcinogenesis
, vol.30
, pp. 377-386
-
-
Greenhough, A.1
Smartt, H.J.2
Moore, A.E.3
-
27
-
-
18444385685
-
Malondialdehyde (MDA) as a lipid peroxidation marker
-
(In Polish)
-
Gawel S, Wardas M, Niedworok E and Wardas P: Malondialdehyde (MDA) as a lipid peroxidation marker. Wiad Lek 57: 453-455, 2004 (In Polish).
-
(2004)
Wiad Lek
, vol.57
, pp. 453-455
-
-
Gawel, S.1
Wardas, M.2
Niedworok, E.3
Wardas, P.4
-
28
-
-
84863291618
-
Oxymatrine attenuates bleomycin-induced pulmonary fibrosis in mice via the inhibition of inducible nitric oxide synthase expression and the TGF-/Smad signaling pathway
-
Liu L, Lu W, Ma Z and Li Z: Oxymatrine attenuates bleomycin-induced pulmonary fibrosis in mice via the inhibition of inducible nitric oxide synthase expression and the TGF-/Smad signaling pathway. Int J Mol Med 29: 815-822, 2012.
-
(2012)
Int J Mol Med
, vol.29
, pp. 815-822
-
-
Liu, L.1
Lu, W.2
Ma, Z.3
Li, Z.4
-
29
-
-
77954734117
-
Inhibitory effect of CXC chemokine receptor 4 antagonist AMD3100 on bleomycin induced murine pulmonary fibrosis
-
Song JS, Kang CM, Kang HH, et al: Inhibitory effect of CXC chemokine receptor 4 antagonist AMD3100 on bleomycin induced murine pulmonary fibrosis. Exp Mol Med 42: 465-472, 2010.
-
(2010)
Exp Mol Med
, vol.42
, pp. 465-472
-
-
Song, J.S.1
Kang, C.M.2
Kang, H.H.3
-
30
-
-
84879682510
-
Sorafenib ameliorates bleomycin-induced pulmonary fibrosis: Potential roles in the inhibition of epithelial-mesenchymal transition and fibroblast activation
-
Chen YL, Zhang X, Bai J, et al: Sorafenib ameliorates bleomycin-induced pulmonary fibrosis: potential roles in the inhibition of epithelial-mesenchymal transition and fibroblast activation. Cell Death Dis 4: e665, 2013.
-
(2013)
Cell Death Dis
, vol.4
, pp. e665
-
-
Chen, Y.L.1
Zhang, X.2
Bai, J.3
-
31
-
-
73649142077
-
Anti-inflammatory effects of tanshinone IIA on radiation-induced microglia BV-2 cells inflammatory response
-
Dong X, Dong J, Zhang R, Fan L, Liu L and Wu G: Anti-inflammatory effects of tanshinone IIA on radiation-induced microglia BV-2 cells inflammatory response. Cancer Biother Radiopharm 24: 681-687, 2009.
-
(2009)
Cancer Biother Radiopharm
, vol.24
, pp. 681-687
-
-
Dong, X.1
Dong, J.2
Zhang, R.3
Fan, L.4
Liu, L.5
Wu, G.6
-
32
-
-
61349154148
-
The anti-inflammatory activities of Tanshinone IIA, an active component of TCM, are mediated by estrogen receptor activation and inhibition of iNOS
-
Fan GW, Gao XM, Wang H, et al: The anti-inflammatory activities of Tanshinone IIA, an active component of TCM, are mediated by estrogen receptor activation and inhibition of iNOS. J Steroid Biochem Mol Biol 113: 275-280, 2009.
-
(2009)
J Steroid Biochem Mol Biol
, vol.113
, pp. 275-280
-
-
Fan, G.W.1
Gao, X.M.2
Wang, H.3
-
33
-
-
78649789528
-
Tanshinone II-A attenuates cardiac fibrosis and modulates collagen metabolism in rats with renovascular hypertension
-
Fang J, Xu SW, Wang P, et al: Tanshinone II-A attenuates cardiac fibrosis and modulates collagen metabolism in rats with renovascular hypertension. Phytomedicine 18: 58-64, 2010.
-
(2010)
Phytomedicine
, vol.18
, pp. 58-64
-
-
Fang, J.1
Xu, S.W.2
Wang, P.3
-
34
-
-
23644461803
-
Oxidative stress in pulmonary fibrosis: A possible role for redox modulatory therapy
-
Kinnula VL, Fattman CL, Tan RJ and Oury TD: Oxidative stress in pulmonary fibrosis: a possible role for redox modulatory therapy. Am J Respir Crit Care Med 172: 417-422, 2005.
-
(2005)
Am J Respir Crit Care Med
, vol.172
, pp. 417-422
-
-
Kinnula, V.L.1
Fattman, C.L.2
Tan, R.J.3
Oury, T.D.4
-
36
-
-
79953661402
-
Tanshinone IIA inhibits angiotensin II-induced cell proliferation in rat cardiac fibroblasts
-
Chan P, Liu JC, Lin LJ, et al: Tanshinone IIA inhibits angiotensin II-induced cell proliferation in rat cardiac fibroblasts. Am J Chin Med 39: 381-394, 2011.
-
(2011)
Am J Chin Med
, vol.39
, pp. 381-394
-
-
Chan, P.1
Liu, J.C.2
Lin, L.J.3
-
37
-
-
84862971779
-
Protective effect of tanshinone IIA on rat kidneys during hypothermic preservation
-
Zhang X, He D, Xu L and Ling S: Protective effect of tanshinone IIA on rat kidneys during hypothermic preservation. Mol Med Rep 5: 405-409, 2012.
-
(2012)
Mol Med Rep
, vol.5
, pp. 405-409
-
-
Zhang, X.1
He, D.2
Xu, L.3
Ling, S.4
-
38
-
-
73649126883
-
Tanshinone IIA induces apoptosis in human lung cancer A549 cells through the induction of reactive oxygen species and decreasing the mitochondrial membrane potential
-
Chiu TL and Su CC: Tanshinone IIA induces apoptosis in human lung cancer A549 cells through the induction of reactive oxygen species and decreasing the mitochondrial membrane potential. Int J Mol Med 25: 231-236, 2010.
-
(2010)
Int J Mol Med
, vol.25
, pp. 231-236
-
-
Chiu, T.L.1
Su, C.C.2
-
39
-
-
0030838509
-
Plasma malondialdehyde as biomarker for oxidative stress: Reference interval and effects of life-style factors
-
Nielsen F, Mikkelsen BB, Nielsen JB, Andersen HR and Grandjean P: Plasma malondialdehyde as biomarker for oxidative stress: reference interval and effects of life-style factors. Clin Chem 43: 1209-1214, 1997.
-
(1997)
Clin Chem
, vol.43
, pp. 1209-1214
-
-
Nielsen, F.1
Mikkelsen, B.B.2
Nielsen, J.B.3
Andersen, H.R.4
Grandjean, P.5
-
40
-
-
45749101298
-
Inhibition of prostaglandin and nitric oxide production in lipopolysaccharide-treated RAW 264. 7 cells by tanshinones from the roots of Salvia miltiorrhiza bunge
-
Jeon SJ, Son KH, Kim YS, Choi YH and Kim HP: Inhibition of prostaglandin and nitric oxide production in lipopolysaccharide-treated RAW 264.7 cells by tanshinones from the roots of Salvia miltiorrhiza bunge. Arch Pharm Res 31: 758-763, 2008.
-
(2008)
Arch Pharm Res
, vol.31
, pp. 758-763
-
-
Jeon, S.J.1
Son, K.H.2
Kim, Y.S.3
Choi, Y.H.4
Kim, H.P.5
-
41
-
-
78651333298
-
Cardioprotective effects of tanshinone IIA pretreatment via kinin B2 receptor-Akt-GSK-3beta dependent pathway in experimental diabetic cardiomyopathy
-
Sun D, Shen M, Li J, et al: Cardioprotective effects of tanshinone IIA pretreatment via kinin B2 receptor-Akt-GSK-3beta dependent pathway in experimental diabetic cardiomyopathy. Cardiovasc Diabetol 10: 4, 2011.
-
(2011)
Cardiovasc Diabetol
, vol.10
, pp. 4
-
-
Sun, D.1
Shen, M.2
Li, J.3
-
42
-
-
65649128507
-
Neuroprotective effects of Tanshinone IIA on permanent focal cerebral ischemia in mice
-
Dong K, Xu W, Yang J, Qiao H and Wu L: Neuroprotective effects of Tanshinone IIA on permanent focal cerebral ischemia in mice. Phytother Res 23: 608-613, 2009.
-
(2009)
Phytother Res
, vol.23
, pp. 608-613
-
-
Dong, K.1
Xu, W.2
Yang, J.3
Qiao, H.4
Wu, L.5
-
43
-
-
33846850150
-
Nitric oxide in the pathogenesis of diffuse pulmonary fibrosis
-
Hsu YC, Wang LF and Chien YW: Nitric oxide in the pathogenesis of diffuse pulmonary fibrosis. Free Radic Biol Med 42: 599-607, 2007.
-
(2007)
Free Radic Biol Med
, vol.42
, pp. 599-607
-
-
Hsu, Y.C.1
Wang, L.F.2
Chien, Y.W.3
-
44
-
-
26244464290
-
Inhibition or knock out of inducible nitric oxide synthase result in resistance to bleomycin-induced lung injury
-
Genovese T, Cuzzocrea S, Di Paola R, et al: Inhibition or knock out of inducible nitric oxide synthase result in resistance to bleomycin-induced lung injury. Respir Res 6: 58, 2005.
-
(2005)
Respir Res
, vol.6
, pp. 58
-
-
Genovese, T.1
Cuzzocrea, S.2
Di Paola, R.3
-
45
-
-
33847684809
-
Tanshinone IIA from Salvia miltiorrhiza induces heme oxygenase-1 expression and inhibits lipopolysaccharide-induced nitric oxide expression in RAW 264
-
Chen TH, Hsu YT, Chen CH, Kao SH and Lee HM: Tanshinone IIA from Salvia miltiorrhiza induces heme oxygenase-1 expression and inhibits lipopolysaccharide-induced nitric oxide expression in RAW 264.7 cells. Mitochondrion 7: 101-105, 2007.
-
(2007)
7 Cells. Mitochondrion
, vol.7
, pp. 101-105
-
-
Chen, T.H.1
Hsu, Y.T.2
Chen, C.H.3
Kao, S.H.4
Lee, H.M.5
-
46
-
-
0345707647
-
Regulatory effects of iNOS on acute lung inflammatory responses in mice
-
Speyer CL, Neff TA, Warner RL, et al: Regulatory effects of iNOS on acute lung inflammatory responses in mice. Am J Pathol 163: 2319-2328, 2003.
-
(2003)
Am J Pathol
, vol.163
, pp. 2319-2328
-
-
Speyer, C.L.1
Neff, T.A.2
Warner, R.L.3
|