Tanshinone IIA attenuates angiotensin II-induced apoptosis via Akt pathway in neonatal rat cardiomyocytes

Acta Pharmacologica Sinica

Volumn 31, Issue 12, 2010, Pages 1569-1575

  Hong, Hong Jye ^a   Liu, Ju Chi ^b   Cheng, Tzu Hurng ^a   Chan, Paul ^b  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Akt; angiotensin II; apoptosis; caspase 3; neonatal cardiomyocytes; reactive oxygen species; tanshinone IIA

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ANGIOTENSIN II; CASPASE 3; CYTOCHROME C; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN BCL XL; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; TANSHINONE IIA; WORTMANNIN;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA STRAND BREAKAGE; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FLOW CYTOMETRY; GENE SILENCING; GENETIC TRANSFECTION; HEART CELL CULTURE; HEART MUSCLE CELL; NEWBORN; NICK END LABELING; NONHUMAN; PROTEIN EXPRESSION; RAT; WESTERN BLOTTING;

ANGIOTENSIN II; ANIMALS; ANIMALS, NEWBORN; ANTIOXIDANTS; APOPTOSIS; CASPASE 3; CELL SURVIVAL; CELLS, CULTURED; CYTOCHROMES C; MYOCYTES, CARDIAC; PHENANTHRENES; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; REACTIVE OXYGEN SPECIES; SALVIA MILTIORRHIZA;

EID: 78649968738     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2010.176     Document Type: Article

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