Design, Synthesis, and Biological Evaluation of Theranostic Vitamin-Linker-Taxoid Conjugates

Journal of Medicinal Chemistry

Volumn 58, Issue 5, 2015, Pages 2406-2416

  Vineberg, Jacob G ^a   Wang, Tao ^a   Zuniga, Edison S ^a   Ojima, Iwao ^a  

^a STONY BROOK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOTIN DERIVATIVE; BIOTIN RECEPTOR; FLUORINE DERIVATIVE; GLUTATHIONE ETHYL ESTER; RECEPTOR; TAXOID; TRACER; UNCLASSIFIED DRUG; BIOTIN; GROWTH FACTOR RECEPTOR; VITAMIN;

ARTICLE; CANCER CELL LINE; CONFOCAL MICROSCOPY; CONJUGATE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG POTENCY; DRUG SCREENING; DRUG SPECIFICITY; DRUG SYNTHESIS; ENDOCYTOSIS; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; IC50; IN VITRO STUDY; INTERNALIZATION; ANIMAL; CELL CULTURE; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; EVALUATION STUDY; FIBROBLAST; LUNG; METABOLISM; MOLECULARLY TARGETED THERAPY; MOUSE; NEOPLASMS;

ANIMALS; BIOTIN; CELLS, CULTURED; DRUG DELIVERY SYSTEMS; DRUG DESIGN; ENDOCYTOSIS; FIBROBLASTS; FLOW CYTOMETRY; HUMANS; LUNG; MICE; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; MOLECULAR TARGETED THERAPY; NEOPLASMS; RECEPTORS, GROWTH FACTOR; TAXOIDS; VITAMINS;

EID: 84924702390     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm5019115     Document Type: Article

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