Mechanism-based tumor-targeting drug delivery system. Validation of efficient vitamin receptor-mediated endocytosis and drug release

Bioconjugate Chemistry

Volumn 21, Issue 5, 2010, Pages 979-987

  Chen, Shuyi ^a   Zhao, Xianrui ^a   Chen, Jingyi ^b   Chen, Jin ^a   Kuznetsova, Larisa ^a   Wong, Stanislaus S ^a,b   Ojima, Iwao ^a  

^a STONY BROOK UNIVERSITY   (United States)

^b BROOKHAVEN NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; CELL CULTURE; CELL MEMBRANES; CONTROLLED DRUG DELIVERY; CYTOTOXICITY; FLUORESCENCE; FLUORESCENCE MICROSCOPY; MOLECULAR BIOLOGY; PROBES; TARGETED DRUG DELIVERY; TUMORS;

CELL LINES; DRUG RELEASE; DRUG-DELIVERY SYSTEMS; MECHANISM-BASED; MOLECULAR PROBES; RECEPTOR-MEDIATED ENDOCYTOSIS; TARGETING DRUG DELIVERIES; TARGETING MOLECULES; TAXOIDS; TUMOR-TARGETING;

COENZYMES;

BIOTIN; DOCETAXEL; FLUORESCEIN; GLUTATHIONE; PACLITAXEL; SBT 1213; SBT 12136 SH; SBT 1214; SBT 1214 FLUORESCEIN; TAXOID; UNCLASSIFIED DRUG; VITAMIN B 7; VITAMIN B GROUP; VITAMIN RECEPTOR;

ANIMAL CELL; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CELL SURFACE; COLON CANCER; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOTOXICITY; DRUG BINDING; DRUG DELIVERY SYSTEM; DRUG RELEASE; ENDOCYTOSIS; FEMALE; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; LEUKEMIA CELL; LUNG CANCER; LUNG FIBROBLAST; MELANOMA; MICROTUBULE; MOLECULAR PROBE; MONITORING; MOUSE; NEOPLASM; NONHUMAN; OVARY CANCER; PANCREAS CANCER; PROTEIN EXPRESSION; SYNTHESIS; TUMOR CELL; VALIDATION STUDY;

EID: 77952579545     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/bc9005656     Document Type: Article

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