Engineering a hollow nanocontainer platform with multifunctional molecular machines for tumor-targeted therapy in vitro and in vivo

ACS Nano

Volumn 7, Issue 11, 2013, Pages 10271-10284

  Luo, Zhong ^a   Ding, Xingwei ^b   Hu, Yan ^b   Wu, Shaojue ^a   Xiang, Yang ^c   Zeng, Yongfei ^a   Zhang, Beilu ^b   Yan, Hong ^a   Zhang, Huacheng ^a   Zhu, Liangliang ^a   Liu, Junjie ^b   Li, Jinghua ^b   Cai, Kaiyong ^b   Zhao, Yanli ^a,d  

^a Nanyang Technological University   (Singapore)

^b CHONGQING UNIVERSITY   (China)

^c THIRD MILITARY MEDICAL UNIVERSITY   (China)

^d NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

Author keywords

hollow mesoporous silica nanoparticles; in vivo; molecular machines; redox responsive release; tumor targeted therapy

Indexed keywords

HOLLOW MESOPOROUS SILICA NANOPARTICLES; IN-VIVO; MOLECULAR MACHINES; REDOX-RESPONSIVE; TUMOR-TARGETED THERAPY;

BIOCOMPATIBILITY; CELL DEATH; CHEMOTHERAPY; COVALENT BONDS; DRUG DELIVERY; NANOTUBES;

TUMORS;

ANTINEOPLASTIC AGENT; BIOMATERIAL; DOXORUBICIN; DRUG CARRIER; NANOPARTICLE; SILICON DIOXIDE;

ANIMAL; APOPTOSIS; ARTICLE; CHEMISTRY; CONFOCAL MICROSCOPY; CYTOLOGY; ENDOCYTOSIS; ENDOTHELIUM CELL; EXPERIMENTAL NEOPLASM; HELA CELL LINE; HUMAN; METABOLISM; METHODOLOGY; MOUSE; NANOTECHNOLOGY; NEOPLASM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUDE MOUSE; OXIDATION REDUCTION REACTION; TRANSMISSION ELECTRON MICROSCOPY;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BIOCOMPATIBLE MATERIALS; DOXORUBICIN; DRUG CARRIERS; ENDOCYTOSIS; ENDOTHELIAL CELLS; HELA CELLS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MICE, NUDE; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; NANOTECHNOLOGY; NEOPLASMS; NEOPLASMS, EXPERIMENTAL; OXIDATION-REDUCTION; SILICON DIOXIDE;

EID: 84888884131     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn404676w     Document Type: Article

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