-
1
-
-
0031040149
-
The development and clinical utility of taxane class of antimicrotubule chemotherapy agents
-
Rowinsky EK: The development and clinical utility of taxane class of antimicrotubule chemotherapy agents. Annu Rev Med 48: 353-374, 1997.
-
(1997)
Annu Rev Med
, vol.48
, pp. 353-374
-
-
Rowinsky, E.K.1
-
3
-
-
0035111779
-
Taxanes in combined modality therapy for solid tumors
-
DOI 10.1016/S1040-8428(00)00112-8, PII S1040842800001128
-
Choy H: Taxanes in combined modality therapy for solid tumors. Crit Rev Oncol Hematol 37: 237-247, 2001. (Pubitemid 32194421)
-
(2001)
Critical Reviews in Oncology/Hematology
, vol.37
, Issue.3
, pp. 237-247
-
-
Choy, H.1
-
4
-
-
0035756986
-
Chemistry and chemical biology of taxane anticancer agents
-
Miller ML and Ojima I: Chemistry and chemical biology of taxane anticancer agents. Chem Record 1: 195-211, 2001.
-
(2001)
Chem Record
, vol.1
, pp. 195-211
-
-
Miller, M.L.1
Ojima, I.2
-
5
-
-
0037868278
-
Signal transduction pathways of taxanes-induced apoptosis
-
DOI 10.2174/1568011033482422
-
Ganansia-Leymarie V, Bischoff P, Bergerat JP and Holl V: Signal transduction pathways of taxane-induced apoptosis. Curr Med Chem Anticancer Agents 3: 291-306, 2003. (Pubitemid 36758303)
-
(2003)
Current Medicinal Chemistry - Anti-Cancer Agents
, vol.3
, Issue.4
, pp. 291-306
-
-
Ganansia-Leymarie, V.1
Bischoff, P.2
Bergerat, J.-P.3
Holl, V.4
-
6
-
-
0345688612
-
Mechanisms of Taxol resistance related to microtubules
-
DOI 10.1038/sj.onc.1206934, Drug Resistance
-
Orr GA, Verdier-Pinard P, McDaid H and Horwitz SB: Mechanisms of taxol resistance related to microtubules. Oncogene 22: 7280-7295, 2003. (Pubitemid 37487160)
-
(2003)
Oncogene
, vol.22
, Issue.47 REV. ISS. 6
, pp. 7280-7295
-
-
Orr, G.A.1
Verdier-Pinard, P.2
McDaid, H.3
Horwitz, S.B.4
-
7
-
-
0031001512
-
Selected physical issues in the structure and function of microtubules
-
DOI 10.1006/jsbi.1997.3843
-
Tuszynski JA, Trpišová B, Sept D and Brown JA: Selected physical issues in the structure and function of microtubules. J Struct Biol 118: 94-106, 1997. (Pubitemid 27208265)
-
(1997)
Journal of Structural Biology
, vol.118
, Issue.2
, pp. 94-106
-
-
Tuszynski, J.A.1
Trpisova, B.2
Sept, D.3
Brown, J.A.4
-
8
-
-
0035188129
-
Managing the centrosome numbers game: From chaos to stability in cancer cell division
-
Brinkley BR: Managing the centrosome numbers game: from chaos to stability in cancer cell division. Trends Cell Biol 11: 18-21, 2001.
-
(2001)
Trends Cell Biol
, vol.11
, pp. 18-21
-
-
Brinkley, B.R.1
-
9
-
-
0027968083
-
Paclitaxel: A review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in the treatment of cancer
-
Spencer MC and Faulds D: Paclitaxel: a review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in the treatment of cancer. Drugs 48: 795-845, 1994.
-
(1994)
Drugs
, vol.48
, pp. 795-845
-
-
Spencer, M.C.1
Faulds, D.2
-
10
-
-
33745918018
-
Insights into the mechanism of microtubule stabilization by Taxol
-
DOI 10.1073/pnas.0603704103
-
Xiao H, Verdier-Pinard P, Fernandez-Fuentes N, Burd B, Angeletti R, Fiser A, Horwitz SB and Orr GA: Insights into the mechanism of microtubule stabilization by Taxol. Proc Natl Acad Sci USA 103: 10166-10173, 2006. (Pubitemid 44051138)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.27
, pp. 10166-10173
-
-
Xiao, H.1
Verdier-Pinard, P.2
Fernandez-Fuentes, N.3
Burd, B.4
Angeletti, R.5
Fiser, A.6
Horwitz, S.B.7
Orr, G.A.8
-
11
-
-
33750948365
-
Novel C2-C3′ N-peptide-linked macrocyclic taxoids. Part 2: Synthesis and biological activities of docetaxel analogues with a peptide side chain at C2 and their macrocyclic derivatives
-
Larroque AL, Dubois J, Thoret S, Aubert G, Chiaroni A, Guéritte F and Guénard D: Novel C2-C3′ N-peptide-linked macrocyclic taxoids. Part 2: synthesis and biological activities of docetaxel analogues with a peptide side chain at C2 and their macrocyclic derivatives. Bioorg Med Chem 15: 563-574, 2007.
-
(2007)
Bioorg Med Chem
, vol.15
, pp. 563-574
-
-
Larroque, A.L.1
Dubois, J.2
Thoret, S.3
Aubert, G.4
Chiaroni, A.5
Guéritte, F.6
Guénard, D.7
-
13
-
-
0036008118
-
Effects of novel taxanes SB-T-1213 and IDN5109 on tubulin polymerization and mitosis
-
DOI 10.1016/S1074-5521(01)00097-7, PII S1074552101000977
-
Jordan MA, Ojima I, Rosas F, Distefano M, Wilson L, Scambia G and Ferlini C: Effects of novel taxanes SB-T-1213 and IDN5109 on tubulin polymerization and mitosis. Chem Biol 9: 93-101, 2002. (Pubitemid 34155868)
-
(2002)
Chemistry and Biology
, vol.9
, Issue.1
, pp. 93-101
-
-
Jordan, M.A.1
Ojima, I.2
Rosas, F.3
Distefano, M.4
Wilson, L.5
Scambia, G.6
Ferlini, C.7
-
14
-
-
0033151262
-
Possible mechanisms of paclitaxel-induced apoptosis
-
Fan W: Possible mechanisms of paclitaxel-induced apoptosis. Biochem Pharmacol 57: 1215-1221, 1999.
-
(1999)
Biochem Pharmacol
, vol.57
, pp. 1215-1221
-
-
Fan, W.1
-
15
-
-
0035899331
-
Integrin signaling inhibits paclitaxel-induced apoptosis in breast cancer cells
-
DOI 10.1038/sj.onc.1204554
-
Aoudjit F and Vuori K: Integrin signaling inhibits paclitaxel-induced apoptosis in breast cancer cells. Oncogene 20: 4995-5004, 2001. (Pubitemid 32769789)
-
(2001)
Oncogene
, vol.20
, Issue.36
, pp. 4995-5004
-
-
Aoudjit, F.1
Vuori, K.2
-
16
-
-
27944468179
-
Cell death induced by taxanes in breast cancer cells: Cytochrome c is released in resistant but not in sensitive cells
-
Ehrlichová M, Koc M, Truksa J, Nad'ová Z, Václavíková R and Kovář J: Cell death induced by taxanes in breast cancer cells: cytochrome c is released in resistant but not in sensitive cells. Anticancer Res 25: 4215-4224, 2005.
-
(2005)
Anticancer Res
, vol.25
, pp. 4215-4224
-
-
Ehrlichová, M.1
Koc, M.2
Truksa, J.3
Nad'ová, Z.4
Václavíková, R.5
Kovář, J.6
-
17
-
-
17344393983
-
IDN5109, a taxane with oral bioavailability and potent antitumor activity
-
Nicoletti MI, Colombo T, Rossi C, Monardo C, Stura S, Zucchetti M, Riva A, Morazzoni P, Donati MB, Bombardelli E, D'Incalci M and Giavazzi R: IDN5109, a taxane with oral bioavailability and potent antitumor activity. Cancer Res 60: 842-846, 2000. (Pubitemid 30129512)
-
(2000)
Cancer Research
, vol.60
, Issue.4
, pp. 842-846
-
-
Nicoletti, M.I.1
Colombo, T.2
Rossi, C.3
Monardo, C.4
Stura, S.5
Zucchetti, M.6
Riva, A.7
Morazzoni, P.8
Donati, M.B.9
Bombardelli, E.10
D'Incalci, M.11
Giavazzi, R.12
-
18
-
-
10144251769
-
Syntheses and structure-activity relationships of the second-generation antitumor taxoids: Exceptional activity against drug-resistant cancer cells
-
DOI 10.1021/jm9604080
-
Ojima I, Slater JC, Michand E, Kuduk SD, Bounaud P-Y, Vrignaud P, Bissery M-C, Veith JM, Pera P and Bernacki RJ: Synthesis and structure-activity relationships of the second-generation antitumor taxoids. Exceptional activity against drug-resistant cancer cells. J Med Chem 39: 3889-3896, 1996. (Pubitemid 26327426)
-
(1996)
Journal of Medicinal Chemistry
, vol.39
, Issue.20
, pp. 3889-3896
-
-
Ojima, I.1
Slater, J.C.2
Michaud, E.3
Kuduk, S.D.4
Bounaud, P.-Y.5
Vrignaud, P.6
Bissery, M.-C.7
Veith, J.M.8
Pera, P.9
Bernacki, R.J.10
-
19
-
-
26244441166
-
Transport and cytotoxicity of paclitaxel, docetaxel, and novel taxanes in human breast cancer cells
-
DOI 10.1007/s00210-005-1080-4
-
Ehrlichová M, Václavíková R, Ojima I, Pepe A, Kuznetsova LV, Chen J, Truksa J, Kovář J and Gut I: Transport and cytotoxicity of paclitaxel, docetaxel, and novel taxanes in human breast cancer cells. N-S Arch Pharmacol 372: 95-105, 2005. (Pubitemid 41414050)
-
(2005)
Naunyn-Schmiedeberg's Archives of Pharmacology
, vol.372
, Issue.1
, pp. 95-105
-
-
Ehrlichova, M.1
Vaclavikova, R.2
Ojima, I.3
Pepe, A.4
Kuznetsova, L.V.5
Chen, J.6
Truksa, J.7
Kovar, J.8
Gut, I.9
-
20
-
-
16844378550
-
The seco-taxane IDN5390 is able to target class III β-tubulin and to overcome paclitaxel resistance
-
DOI 10.1158/0008-5472.CAN-04-3065
-
Ferlini C, Raspaglio G, Mozzetti S, Cicchillitti L, Filippetti F, Gallo D, Fattorusso C, Campiani G and Scambia G: The secotaxane IDN5390 is able to target class III beta-tubulin and to overcome paclitaxel resistance. Cancer Res 65: 2397-2405, 2005. (Pubitemid 40490151)
-
(2005)
Cancer Research
, vol.65
, Issue.6
, pp. 2397-2405
-
-
Ferlini, C.1
Raspaglio, G.2
Mozzetti, S.3
Cicchillitti, L.4
Filippetti, F.5
Gallo, D.6
Fattorusso, C.7
Campiani, G.8
Scambia, G.9
-
21
-
-
33746471989
-
Novel agents that target tubulin and related elements
-
Rowinsky EK and Calvo E: Novel agents that target tubulin and related elements. Semin Oncol 33: 421-435, 2006.
-
(2006)
Semin Oncol
, vol.33
, pp. 421-435
-
-
Rowinsky, E.K.1
Calvo, E.2
-
22
-
-
0035801843
-
Additive stimulatory effect of extracellular calcium and potassium on non-transferrin ferric iron uptake by HeLa and K562 cells
-
Musílková J and Kovář J: Additive stimulatory effect of extracellular calcium and potassium on non-transferrin ferric iron uptake by HeLa and K562 cells. Biochim Biophys Acta 1514: 117-126, 2001.
-
(2001)
Biochim Biophys Acta
, vol.1514
, pp. 117-126
-
-
Musílková, J.1
Kovář, J.2
-
23
-
-
0034838232
-
Differing sensitivity of tumor cells to apoptosis induced by iron deprivation in vitro
-
DOI 10.1290/1071-2690(2001)037<0450:DSOTCT>2.0.CO;2
-
Kovář J, Valenta T and Štýbrová H: Differing sensitivity of tumor cells to apoptosis induced by iron deprivation in vitro. In Vitro Cell Dev Biol Anim 37: 450-458, 2001. (Pubitemid 32880543)
-
(2001)
In Vitro Cellular and Developmental Biology - Animal
, vol.37
, Issue.7
, pp. 450-458
-
-
Kovar, J.1
Valenta, T.2
Stybrova, H.3
-
24
-
-
18044363070
-
Iron deprivation induces apoptosis via mitochondrial changes related to Bax translocation
-
Koc M, Nad'ová Z, Truksa J, Ehrlichová M and Kovář J: Iron deprivation induces apoptosis via mitochondrial changes related to Bax translocation. Apoptosis 10: 381-393, 2005.
-
(2005)
Apoptosis
, vol.10
, pp. 381-393
-
-
Koc, M.1
Nad'ová, Z.2
Truksa, J.3
Ehrlichová, M.4
Kovář, J.5
-
25
-
-
0022186670
-
Measurement of protein using bicinchoninic acid
-
Smith PK, Krohn RI, Hermanson GT, Mallia AK, Gartner FH, Provenzano MD, Fujimoto EK, Goeke NM, Olson BJ and Klenk DC: Measurement of protein using bicinchoninic acid. Anal Biochem 150: 76-85, 1985.
-
(1985)
Anal Biochem
, vol.150
, pp. 76-85
-
-
Smith, P.K.1
Krohn, R.I.2
Hermanson, G.T.3
Mallia, A.K.4
Gartner, F.H.5
Provenzano, M.D.6
Fujimoto, E.K.7
Goeke, N.M.8
Olson, B.J.9
Klenk, D.C.10
-
26
-
-
0345275866
-
Gene Expression and Mitotic Exit Induced by Microtubule-Stabilizing Drugs
-
Chen JG, Yang CP, Cammer M and Horwitz SB: Gene expression and mitotic exit induced by microtubule-stabilizing drugs. Cancer Res 63: 7891-7899, 2003. (Pubitemid 37466724)
-
(2003)
Cancer Research
, vol.63
, Issue.22
, pp. 7891-7899
-
-
Chen, J.-G.1
Yang, C.-P.H.2
Cammer, M.3
Horwitz, S.B.4
-
27
-
-
26444449908
-
Low concentrations of taxol cause mitotic delay followed by premature dissociation of p55CDC from Mad2 and BubR1 and abrogation of the spindle checkpoint, leading to aneuploidy
-
Ikui AE, Yang CH, Matsumoto T and Horwitz SB: Low concentrations of taxol cause mitotic delay followed by premature dissociation of p55CDC from Mad2 and BubR1 and abrogation of the spindle checkpoint, leading to aneuploidy. Cell Cycle 4: 1385-1388, 2005. (Pubitemid 41437128)
-
(2005)
Cell Cycle
, vol.4
, Issue.10
, pp. 1385-1388
-
-
Ikui, A.E.1
Chia-Ping, H.Y.2
Matsumoto, T.3
Horwitz, S.B.4
-
29
-
-
0032529464
-
Mechanisms of taxol-induced cell death are concentration dependent
-
Torres K and Horwitz SB: Mechanisms of taxol-induced cell death are concentration dependent. Cancer Res 58: 3620-3626, 1998. (Pubitemid 28376560)
-
(1998)
Cancer Research
, vol.58
, Issue.16
, pp. 3620-3626
-
-
Torres, K.1
Horwitz, S.B.2
-
30
-
-
0033055735
-
Comparison of paclitaxel-, 5-fluoro-2′-deoxyuridine-, and epidermal growth factor (EGF)-induced apoptosis: Evidence for EGF-induced anoikis
-
Kottke TJ, Blajeski AL, Martins LM, Mesner PW Jr, Davidson NE, Earnshaw WC, Armstrong DK and Kaufmann SH: Comparison of paclitaxel-, 5-fluoro-2′-deoxyuridine-, and epidermal growth factor (EGF)-induced apoptosis. Evidence for EGF-induced anoikis. J Biol Chem 274: 15927-15936, 1999. (Pubitemid 129518958)
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.22
, pp. 15927-15936
-
-
Kottke, T.J.1
Blajeski, A.L.2
Martins, L.M.3
Mesner Jr., P.W.4
Davidson, N.E.5
Earnshaw, W.C.6
Armstrong, D.K.7
Kaufmann, S.H.8
-
31
-
-
0035901938
-
Overexpression of caspase-3 restores sensitivity for drug-induced apoptosis in breast cancer cell lines with acquired drug resistance
-
DOI 10.1038/sj.onc.1204342
-
Friedrich K, Wieder T, Von Haefen C, Radetzki S, Janicke R, Schulze-Osthoff K, Dorken B and Daniel PT: Overexpression of caspase-3 restores sensitivity for drug-induced apoptosis in breast cancer cell lines with acquired drug resistance. Oncogene 20: 2749-2760, 2001. (Pubitemid 32549832)
-
(2001)
Oncogene
, vol.20
, Issue.22
, pp. 2749-2760
-
-
Friedrich, K.1
Wieder, T.2
Von Haefen, C.3
Radetzki, S.4
Janicke, R.5
Schulze-Osthoff, K.6
Dorken, B.7
Daniel, P.T.8
-
32
-
-
0037021417
-
Paclitaxel targets mitochondria upstream of caspase activation in intact human neuroblastoma cells
-
DOI 10.1016/S0014-5793(02)03691-8, PII S0014579302036918
-
André N, Carré M, Brasseur G, Pourroy B, Kovacic H, Briand C and Braguer D: Paclitaxel targets mitochondria upstream of caspase activation in intact human neuroblastoma cells. FEBS Lett 532: 256-260, 2002. (Pubitemid 35375900)
-
(2002)
FEBS Letters
, vol.532
, Issue.1-2
, pp. 256-260
-
-
Andre, N.1
Carre, M.2
Brasseur, G.3
Pourroy, B.4
Kovacic, H.5
Briand, C.6
Braguer, D.7
-
33
-
-
0037085048
-
Variation in the kinetics of caspase-3 activation, Bcl-2 phosphorylation and apoptotic morphology in unselected human ovarian cancer cell lines as a response to docetaxel
-
Kolfschoten G, Hulscher TM, Duyndam MCA, Pinedo HM and Boven E: Variation in the kinetics of caspase-3 activation, Bcl-2 phosphorylation and apoptotic morphology in unselected human ovarian cancer cell lines as a response to docetaxel. Biochem Pharmacol 63: 733-743, 2002.
-
(2002)
Biochem Pharmacol
, vol.63
, pp. 733-743
-
-
Kolfschoten, G.1
Hulscher, T.M.2
Duyndam, M.C.A.3
Pinedo, H.M.4
Boven, E.5
-
34
-
-
51049100659
-
Activation of the mitochondria-driven pathway of apoptosis in human PC-3 prostate cancer cells by a novel hydrophilic paclitaxel derivative, 7-xylosyl-10-deacetylpaclitaxel
-
Jiang S, Zu Y, Fu Y, Zhang Y and Efferth T: Activation of the mitochondria-driven pathway of apoptosis in human PC-3 prostate cancer cells by a novel hydrophilic paclitaxel derivative, 7-xylosyl-10-deacetylpaclitaxel. Int J Oncol 33: 103-111, 2008.
-
(2008)
Int J Oncol
, vol.33
, pp. 103-111
-
-
Jiang, S.1
Zu, Y.2
Fu, Y.3
Zhang, Y.4
Efferth, T.5
-
36
-
-
44149087374
-
Caspase-2 is required for cell death induced by cytoskeletal disruption
-
DOI 10.1038/sj.onc.1211005, PII 1211005
-
Ho LH, Read SH, Dorstyn L, Lambrusco L and Kumar S: Caspase-2 is required for cell death induced by cytoskeletal disruption. Oncogene 27: 3393-3404, 2008. (Pubitemid 351769315)
-
(2008)
Oncogene
, vol.27
, Issue.24
, pp. 3393-3404
-
-
Ho, L.H.1
Read, S.H.2
Dorstyn, L.3
Lambrusco, L.4
Kumar, S.5
-
37
-
-
12244251385
-
Involvement of mitochondrial pathway in Taxol-induced apoptosis of human T24 bladder cancer cells
-
DOI 10.1007/s00240-002-0263-4
-
Yuan SY, Hsu SL, Tsai KJ and Yang CR: Involvement of mitochondrial pathway in taxol-induced apoptosis of human T24 bladder cancer cells. Urol Res 30: 282-288, 2002. (Pubitemid 36056636)
-
(2002)
Urological Research
, vol.30
, Issue.5
, pp. 282-288
-
-
Yuan, S.-Y.1
Hsu, S.-L.2
Tsai, K.-J.3
Yang, C.-R.4
-
38
-
-
4644279356
-
Involvement of oxidative stress and caspase activation in paclitaxel-induced apoptosis of primary effusion lymphoma cells
-
DOI 10.1007/s00280-004-0831-0
-
Wang YF, Chen CY, Chung SF, Chiou YH and Lo HR: Involvement of oxidative stress and caspase activation in paclitaxel-induced apoptosis of primary effusion lymphoma cells. Cancer Chemother Pharmacol 54: 322-330, 2004. (Pubitemid 39304427)
-
(2004)
Cancer Chemotherapy and Pharmacology
, vol.54
, Issue.4
, pp. 322-330
-
-
Wang, Y.-F.1
Chen, C.-Y.2
Chung, S.-F.3
Chiou, Y.-H.4
Lo, H.-R.5
-
39
-
-
33847368592
-
Docetaxel-induced apoptosis in melanoma cells is dependent on activation of caspase-2
-
DOI 10.1158/1535-7163.MCT-06-0564
-
Mhaidat NM, Wang Y, Kiejda KA, Zhang XD and Hersey P: Docetaxel-induced apoptosis in melanoma cells is dependent on activation of caspase-2. Mol Cancer Ther 6: 752-761, 2007. (Pubitemid 46332476)
-
(2007)
Molecular Cancer Therapeutics
, vol.6
, Issue.2
, pp. 752-761
-
-
Mhaidat, N.M.1
Wang, Y.2
Kiejda, K.A.3
Zhang, X.D.4
Hersey, P.5
-
40
-
-
0347986652
-
HOXA5-Induced Apoptosis in Breast Cancer Cells Is Mediated by Caspases 2 and 8
-
DOI 10.1128/MCB.24.2.924-935.2004
-
Chen H, Chung S and Sukumar S: HOXA5-induced apoptosis in breast cancer cells is mediated by caspase 2 and 8. Mol Cell Biol 24: 924-935, 2004. (Pubitemid 38057941)
-
(2004)
Molecular and Cellular Biology
, vol.24
, Issue.2
, pp. 924-935
-
-
Chen, H.1
Chung, S.2
Sukumar, S.3
-
41
-
-
33645284756
-
Mitotic catastrophe results in cell death by caspase-dependent and caspase-independent mechanisms
-
Mansilla S, Priebe W and Portugal J: Mitotic catastrophe results in cell death by caspase-dependent and caspase-independent mechanisms. Cell Cycle 5: 53-60, 2006.
-
(2006)
Cell Cycle
, vol.5
, pp. 53-60
-
-
Mansilla, S.1
Priebe, W.2
Portugal, J.3
-
42
-
-
33847760992
-
The nuclear receptor interacting factor-3 transcriptional coregulator mediates rapid apoptosis in breast cancer cells through direct and bystander-mediated events
-
DOI 10.1158/0008-5472.CAN-06-4034
-
Das S, Nwachukwu JC, Li D, Vulin AI, Martinez-Caballero S, Kinnally KW and Samuels HH: The nuclear receptor interacting factor-3 transcriptional coregulator mediates rapid apoptosis in breast cancer cells through direct and bystander-mediated events. Cancer Res 67: 1775-1782, 2007. (Pubitemid 46383405)
-
(2007)
Cancer Research
, vol.67
, Issue.4
, pp. 1775-1782
-
-
Das, S.1
Nwachukwu, J.C.2
Li, D.3
Vulin, A.I.4
Martinez-Caballero, S.5
Kinnally, K.W.6
Samuels, H.H.7
|