메뉴 건너뛰기




Volumn 21, Issue 3, 2015, Pages 172-183

Polymicrobial synergy and dysbiosis in inflammatory disease

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT;

EID: 84924630982     PISSN: 14714914     EISSN: 1471499X     Source Type: Journal    
DOI: 10.1016/j.molmed.2014.11.004     Document Type: Review
Times cited : (401)

References (90)
  • 1
    • 84869006781 scopus 로고    scopus 로고
    • Beyond the red complex and into more complexity: the Polymicrobial Synergy and Dysbiosis (PSD) model of periodontal disease etiology
    • Hajishengallis G., Lamont R.J. Beyond the red complex and into more complexity: the Polymicrobial Synergy and Dysbiosis (PSD) model of periodontal disease etiology. Mol. Oral Microbiol. 2012, 27:409-419.
    • (2012) Mol. Oral Microbiol. , vol.27 , pp. 409-419
    • Hajishengallis, G.1    Lamont, R.J.2
  • 2
    • 78650647326 scopus 로고    scopus 로고
    • Has the microbiota played a critical role in the evolution of the adaptive immune system?
    • Lee Y.K., Mazmanian S.K. Has the microbiota played a critical role in the evolution of the adaptive immune system?. Science 2010, 330:1768-1773.
    • (2010) Science , vol.330 , pp. 1768-1773
    • Lee, Y.K.1    Mazmanian, S.K.2
  • 3
    • 81755166205 scopus 로고    scopus 로고
    • Low-abundance biofilm species orchestrates inflammatory periodontal disease through the commensal microbiota and complement
    • Hajishengallis G., et al. Low-abundance biofilm species orchestrates inflammatory periodontal disease through the commensal microbiota and complement. Cell Host Microbe 2011, 10:497-506.
    • (2011) Cell Host Microbe , vol.10 , pp. 497-506
    • Hajishengallis, G.1
  • 4
    • 79960169778 scopus 로고    scopus 로고
    • The pathogenic persona of community-associated oral streptococci
    • Whitmore S.E., Lamont R.J. The pathogenic persona of community-associated oral streptococci. Mol. Microbiol. 2011, 81:305-314.
    • (2011) Mol. Microbiol. , vol.81 , pp. 305-314
    • Whitmore, S.E.1    Lamont, R.J.2
  • 5
    • 84911397225 scopus 로고    scopus 로고
    • The inflammophilic character of the periodontitis-associated microbiota
    • Hajishengallis G. The inflammophilic character of the periodontitis-associated microbiota. Mol. Oral Microbiol. 2014, 29:248-257.
    • (2014) Mol. Oral Microbiol. , vol.29 , pp. 248-257
    • Hajishengallis, G.1
  • 6
    • 84891372427 scopus 로고    scopus 로고
    • Immunomicrobial pathogenesis of periodontitis: keystones, pathobionts, and host response
    • Hajishengallis G. Immunomicrobial pathogenesis of periodontitis: keystones, pathobionts, and host response. Trends Immunol. 2014, 35:3-11.
    • (2014) Trends Immunol. , vol.35 , pp. 3-11
    • Hajishengallis, G.1
  • 7
    • 84908331085 scopus 로고    scopus 로고
    • Disruption of heterotypic community development by Porphyromonas gingivalis with small molecule inhibitors
    • Wright C.J., et al. Disruption of heterotypic community development by Porphyromonas gingivalis with small molecule inhibitors. Mol. Oral Microbiol. 2014, 29:185-193.
    • (2014) Mol. Oral Microbiol. , vol.29 , pp. 185-193
    • Wright, C.J.1
  • 8
    • 27844560086 scopus 로고    scopus 로고
    • Oral microbial communities in sickness and in health
    • Jenkinson H.F., Lamont R.J. Oral microbial communities in sickness and in health. Trends Microbiol. 2005, 13:589-595.
    • (2005) Trends Microbiol. , vol.13 , pp. 589-595
    • Jenkinson, H.F.1    Lamont, R.J.2
  • 9
    • 77953616099 scopus 로고    scopus 로고
    • Periodontitis: a polymicrobial disruption of host homeostasis
    • Darveau R.P. Periodontitis: a polymicrobial disruption of host homeostasis. Nat. Rev. Microbiol. 2010, 8:481-490.
    • (2010) Nat. Rev. Microbiol. , vol.8 , pp. 481-490
    • Darveau, R.P.1
  • 10
    • 33644855778 scopus 로고    scopus 로고
    • Host responses in maintaining periodontal health and determining periodontal disease
    • Schenkein H.A. Host responses in maintaining periodontal health and determining periodontal disease. Periodontol. 2000 2006, 40:77-93.
    • (2006) Periodontol. 2000 , vol.40 , pp. 77-93
    • Schenkein, H.A.1
  • 11
    • 84893587232 scopus 로고    scopus 로고
    • Breaking bad: manipulation of the host response by Porphyromonas gingivalis
    • Hajishengallis G., Lamont R.J. Breaking bad: manipulation of the host response by Porphyromonas gingivalis. Eur. J. Immunol. 2014, 44:328-338.
    • (2014) Eur. J. Immunol. , vol.44 , pp. 328-338
    • Hajishengallis, G.1    Lamont, R.J.2
  • 12
    • 84865276077 scopus 로고    scopus 로고
    • Porphyromonas gingivalis as a potential community activist for disease
    • Darveau R.P., et al. Porphyromonas gingivalis as a potential community activist for disease. J. Dent. Res. 2012, 91:816-820.
    • (2012) J. Dent. Res. , vol.91 , pp. 816-820
    • Darveau, R.P.1
  • 13
    • 84877871524 scopus 로고    scopus 로고
    • Induction of bone loss by pathobiont-mediated nod1 signaling in the oral cavity
    • Jiao Y., et al. Induction of bone loss by pathobiont-mediated nod1 signaling in the oral cavity. Cell Host Microbe 2013, 13:595-601.
    • (2013) Cell Host Microbe , vol.13 , pp. 595-601
    • Jiao, Y.1
  • 14
    • 77957357555 scopus 로고    scopus 로고
    • The human oral microbiome
    • Dewhirst F.E., et al. The human oral microbiome. J. Bacteriol. 2010, 192:5002-5017.
    • (2010) J. Bacteriol. , vol.192 , pp. 5002-5017
    • Dewhirst, F.E.1
  • 15
    • 84876842615 scopus 로고    scopus 로고
    • The subgingival microbiome in health and periodontitis and its relationship with community biomass and inflammation
    • Abusleme L., et al. The subgingival microbiome in health and periodontitis and its relationship with community biomass and inflammation. ISME J. 2013, 7:1016-1025.
    • (2013) ISME J. , vol.7 , pp. 1016-1025
    • Abusleme, L.1
  • 16
    • 84861342868 scopus 로고    scopus 로고
    • Distinct and complex bacterial profiles in human periodontitis and health revealed by 16S pyrosequencing
    • Griffen A.L., et al. Distinct and complex bacterial profiles in human periodontitis and health revealed by 16S pyrosequencing. ISME J. 2012, 6:1176-1185.
    • (2012) ISME J. , vol.6 , pp. 1176-1185
    • Griffen, A.L.1
  • 17
    • 34248635940 scopus 로고    scopus 로고
    • Changes in periodontal health status are associated with bacterial community shifts as assessed by quantitative 16S cloning and sequencing
    • Kumar P.S., et al. Changes in periodontal health status are associated with bacterial community shifts as assessed by quantitative 16S cloning and sequencing. J. Clin. Microbiol. 2006, 44:3665-3673.
    • (2006) J. Clin. Microbiol. , vol.44 , pp. 3665-3673
    • Kumar, P.S.1
  • 18
    • 84904993698 scopus 로고    scopus 로고
    • Community-wide transcriptome of the oral microbiome in subjects with and without periodontitis
    • Duran-Pinedo A.E., et al. Community-wide transcriptome of the oral microbiome in subjects with and without periodontitis. ISME J. 2014, 8:1659-1672.
    • (2014) ISME J. , vol.8 , pp. 1659-1672
    • Duran-Pinedo, A.E.1
  • 19
    • 84863989936 scopus 로고    scopus 로고
    • A bacterial driver-passenger model for colorectal cancer: beyond the usual suspects
    • Tjalsma H., et al. A bacterial driver-passenger model for colorectal cancer: beyond the usual suspects. Nat. Rev. Microbiol. 2012, 10:575-582.
    • (2012) Nat. Rev. Microbiol. , vol.10 , pp. 575-582
    • Tjalsma, H.1
  • 20
    • 34147159390 scopus 로고    scopus 로고
    • Rat model of polymicrobial infection, immunity, and alveolar bone resorption in periodontal disease
    • Kesavalu L., et al. Rat model of polymicrobial infection, immunity, and alveolar bone resorption in periodontal disease. Infect. Immun. 2007, 75:1704-1712.
    • (2007) Infect. Immun. , vol.75 , pp. 1704-1712
    • Kesavalu, L.1
  • 21
    • 84864192030 scopus 로고    scopus 로고
    • Insights into the virulence of oral biofilms: discoveries from proteomics
    • Kuboniwa M., et al. Insights into the virulence of oral biofilms: discoveries from proteomics. Expert Rev. Proteomics 2012, 9:311-323.
    • (2012) Expert Rev. Proteomics , vol.9 , pp. 311-323
    • Kuboniwa, M.1
  • 22
    • 84861209251 scopus 로고    scopus 로고
    • Effect of periodontal pathogens on the metatranscriptome of a healthy multispecies biofilm model
    • Frias-Lopez J., Duran-Pinedo A. Effect of periodontal pathogens on the metatranscriptome of a healthy multispecies biofilm model. J. Bacteriol. 2012, 194:2082-2095.
    • (2012) J. Bacteriol. , vol.194 , pp. 2082-2095
    • Frias-Lopez, J.1    Duran-Pinedo, A.2
  • 23
    • 84876197055 scopus 로고    scopus 로고
    • Evidence of mutualism between two periodontal pathogens: co-operative haem acquisition by the HmuY haemophore of Porphyromonas gingivalis and the cysteine protease interpain A (InpA) of Prevotella intermedia
    • Byrne D.P., et al. Evidence of mutualism between two periodontal pathogens: co-operative haem acquisition by the HmuY haemophore of Porphyromonas gingivalis and the cysteine protease interpain A (InpA) of Prevotella intermedia. Mol. Oral Microbiol. 2013, 28:219-229.
    • (2013) Mol. Oral Microbiol. , vol.28 , pp. 219-229
    • Byrne, D.P.1
  • 24
    • 84897396852 scopus 로고    scopus 로고
    • Porphyromonas gingivalis and Treponema denticola exhibit metabolic symbioses
    • Tan K.H., et al. Porphyromonas gingivalis and Treponema denticola exhibit metabolic symbioses. PLoS Pathog. 2014, 10:e1003955.
    • (2014) PLoS Pathog. , vol.10 , pp. e1003955
    • Tan, K.H.1
  • 25
    • 84872396139 scopus 로고    scopus 로고
    • Treponema denticola improves adhesive capacities of Porphyromonas gingivalis
    • Meuric V., et al. Treponema denticola improves adhesive capacities of Porphyromonas gingivalis. Mol. Oral Microbiol. 2013, 28:40-53.
    • (2013) Mol. Oral Microbiol. , vol.28 , pp. 40-53
    • Meuric, V.1
  • 26
    • 84875045260 scopus 로고    scopus 로고
    • Microbial interactions in building of communities
    • Wright C.J., et al. Microbial interactions in building of communities. Mol. Oral Microbiol. 2013, 28:83-101.
    • (2013) Mol. Oral Microbiol. , vol.28 , pp. 83-101
    • Wright, C.J.1
  • 27
    • 84902208556 scopus 로고    scopus 로고
    • Characterization of a bacterial tyrosine kinase in Porphyromonas gingivalis involved in polymicrobial synergy
    • Wright C.J., et al. Characterization of a bacterial tyrosine kinase in Porphyromonas gingivalis involved in polymicrobial synergy. Microbiologyopen 2014, 3:383-394.
    • (2014) Microbiologyopen , vol.3 , pp. 383-394
    • Wright, C.J.1
  • 28
    • 49249093047 scopus 로고    scopus 로고
    • A Porphyromonas gingivalis tyrosine phosphatase is a multifunctional regulator of virulence attributes
    • Maeda K., et al. A Porphyromonas gingivalis tyrosine phosphatase is a multifunctional regulator of virulence attributes. Mol. Microbiol. 2008, 69:1153-1164.
    • (2008) Mol. Microbiol. , vol.69 , pp. 1153-1164
    • Maeda, K.1
  • 29
    • 78649990332 scopus 로고    scopus 로고
    • Community signalling between Streptococcus gordonii and Porphyromonas gingivalis is controlled by the transcriptional regulator CdhR
    • Chawla A., et al. Community signalling between Streptococcus gordonii and Porphyromonas gingivalis is controlled by the transcriptional regulator CdhR. Mol. Microbiol. 2010, 78:1510-1522.
    • (2010) Mol. Microbiol. , vol.78 , pp. 1510-1522
    • Chawla, A.1
  • 30
    • 78650892286 scopus 로고    scopus 로고
    • Structural dissection and in vivo effectiveness of a peptide inhibitor of Porphyromonas gingivalis adherence to Streptococcus gordonii
    • Daep C.A., et al. Structural dissection and in vivo effectiveness of a peptide inhibitor of Porphyromonas gingivalis adherence to Streptococcus gordonii. Infect. Immun. 2011, 79:67-74.
    • (2011) Infect. Immun. , vol.79 , pp. 67-74
    • Daep, C.A.1
  • 31
    • 79953284689 scopus 로고    scopus 로고
    • Metabolite cross-feeding enhances virulence in a model polymicrobial infection
    • Ramsey M.M., et al. Metabolite cross-feeding enhances virulence in a model polymicrobial infection. PLoS Pathog. 2011, 7:e1002012.
    • (2011) PLoS Pathog. , vol.7 , pp. e1002012
    • Ramsey, M.M.1
  • 32
    • 84901684205 scopus 로고    scopus 로고
    • Bacterial fight-and-flight responses enhance virulence in a polymicrobial infection
    • Stacy A., et al. Bacterial fight-and-flight responses enhance virulence in a polymicrobial infection. Proc. Natl. Acad. Sci. U.S.A. 2014, 111:7819-7824.
    • (2014) Proc. Natl. Acad. Sci. U.S.A. , vol.111 , pp. 7819-7824
    • Stacy, A.1
  • 33
    • 77953237901 scopus 로고    scopus 로고
    • Aggregatibacter actinomycetemcomitans leukotoxin: from threat to therapy
    • Kachlany S.C. Aggregatibacter actinomycetemcomitans leukotoxin: from threat to therapy. J. Dent. Res. 2010, 89:561-570.
    • (2010) J. Dent. Res. , vol.89 , pp. 561-570
    • Kachlany, S.C.1
  • 34
    • 71549142866 scopus 로고    scopus 로고
    • Negative correlation of distributions of Streptococcus cristatus and Porphyromonas gingivalis in subgingival plaque
    • Wang B.Y., et al. Negative correlation of distributions of Streptococcus cristatus and Porphyromonas gingivalis in subgingival plaque. J. Clin. Microbiol. 2009, 47:3902-3906.
    • (2009) J. Clin. Microbiol. , vol.47 , pp. 3902-3906
    • Wang, B.Y.1
  • 35
    • 84865559445 scopus 로고    scopus 로고
    • Streptococcus cristatus ArcA interferes with Porphyromonas gingivalis pathogenicity in mice
    • Xie H., et al. Streptococcus cristatus ArcA interferes with Porphyromonas gingivalis pathogenicity in mice. J. Periodontal Res. 2012, 47:578-583.
    • (2012) J. Periodontal Res. , vol.47 , pp. 578-583
    • Xie, H.1
  • 36
    • 84860511582 scopus 로고    scopus 로고
    • The Black Queen Hypothesis: evolution of dependencies through adaptive gene loss
    • e00036-e00012
    • Morris J.J., et al. The Black Queen Hypothesis: evolution of dependencies through adaptive gene loss. MBio 2012, 3:e00036-12.
    • (2012) MBio , vol.3
    • Morris, J.J.1
  • 37
    • 18044388426 scopus 로고    scopus 로고
    • Distinct transcriptional profiles characterize oral epithelium-microbiota interactions
    • Handfield M., et al. Distinct transcriptional profiles characterize oral epithelium-microbiota interactions. Cell Microbiol. 2005, 7:811-823.
    • (2005) Cell Microbiol. , vol.7 , pp. 811-823
    • Handfield, M.1
  • 38
    • 84867358999 scopus 로고    scopus 로고
    • Porphyromonas gingivalis entry into gingival epithelial cells modulated by Fusobacterium nucleatum is dependent on lipid rafts
    • Saito A., et al. Porphyromonas gingivalis entry into gingival epithelial cells modulated by Fusobacterium nucleatum is dependent on lipid rafts. Microb. Pathog. 2012, 53:234-242.
    • (2012) Microb. Pathog. , vol.53 , pp. 234-242
    • Saito, A.1
  • 39
    • 84905856404 scopus 로고    scopus 로고
    • Filifactor alocis: the newly discovered kid on the block with special talents
    • Aruni W., et al. Filifactor alocis: the newly discovered kid on the block with special talents. J. Dent. Res. 2014, 93:725-732.
    • (2014) J. Dent. Res. , vol.93 , pp. 725-732
    • Aruni, W.1
  • 40
    • 41149169190 scopus 로고    scopus 로고
    • Beyond good and evil in the oral cavity: insights into host-microbe relationships derived from transcriptional profiling of gingival cells
    • Handfield M., et al. Beyond good and evil in the oral cavity: insights into host-microbe relationships derived from transcriptional profiling of gingival cells. J. Dent. Res. 2008, 87:203-223.
    • (2008) J. Dent. Res. , vol.87 , pp. 203-223
    • Handfield, M.1
  • 41
    • 0032036517 scopus 로고    scopus 로고
    • Local chemokine paralysis, a novel pathogenic mechanism for Porphyromonas gingivalis
    • Darveau R.P., et al. Local chemokine paralysis, a novel pathogenic mechanism for Porphyromonas gingivalis. Infect. Immun. 1998, 66:1660-1665.
    • (1998) Infect. Immun. , vol.66 , pp. 1660-1665
    • Darveau, R.P.1
  • 42
    • 84876829405 scopus 로고    scopus 로고
    • The serine phosphatase SerB of Porphyromonas gingivalis suppresses IL-8 production by dephosphorylation of NF-κB RelA/p65
    • Takeuchi H., et al. The serine phosphatase SerB of Porphyromonas gingivalis suppresses IL-8 production by dephosphorylation of NF-κB RelA/p65. PLoS Pathog. 2013, 9:e1003326.
    • (2013) PLoS Pathog. , vol.9 , pp. e1003326
    • Takeuchi, H.1
  • 43
    • 0028902201 scopus 로고
    • Ability of bacteria associated with chronic inflammatory disease to stimulate E-selectin expression and promote neutrophil adhesion
    • Darveau R.P., et al. Ability of bacteria associated with chronic inflammatory disease to stimulate E-selectin expression and promote neutrophil adhesion. Infect. Immun. 1995, 63:1311-1317.
    • (1995) Infect. Immun. , vol.63 , pp. 1311-1317
    • Darveau, R.P.1
  • 44
    • 78049449136 scopus 로고    scopus 로고
    • Role of Porphyromonas gingivalis phosphoserine phosphatase enzyme SerB in inflammation, immune response, and induction of alveolar bone resorption in rats
    • Bainbridge B., et al. Role of Porphyromonas gingivalis phosphoserine phosphatase enzyme SerB in inflammation, immune response, and induction of alveolar bone resorption in rats. Infect. Immun. 2010, 78:4560-4569.
    • (2010) Infect. Immun. , vol.78 , pp. 4560-4569
    • Bainbridge, B.1
  • 45
    • 84879458372 scopus 로고    scopus 로고
    • Suppression of T-cell chemokines by Porphyromonas gingivalis
    • Jauregui C.E., et al. Suppression of T-cell chemokines by Porphyromonas gingivalis. Infect. Immun. 2013, 81:2288-2295.
    • (2013) Infect. Immun. , vol.81 , pp. 2288-2295
    • Jauregui, C.E.1
  • 46
    • 33846045743 scopus 로고    scopus 로고
    • The role of T cells in periodontal disease: homeostasis and autoimmunity
    • Gemmell E., et al. The role of T cells in periodontal disease: homeostasis and autoimmunity. Periodontol. 2000 2007, 43:14-40.
    • (2007) Periodontol. 2000 , vol.43 , pp. 14-40
    • Gemmell, E.1
  • 47
    • 84869857368 scopus 로고    scopus 로고
    • Porphyromonas gingivalis promotes Th17 inducing pathways in chronic periodontitis
    • Moutsopoulos N.M., et al. Porphyromonas gingivalis promotes Th17 inducing pathways in chronic periodontitis. J. Autoimmun. 2012, 39:294-303.
    • (2012) J. Autoimmun. , vol.39 , pp. 294-303
    • Moutsopoulos, N.M.1
  • 48
    • 84884284271 scopus 로고    scopus 로고
    • A periodontal pathogen Treponema denticola hijacks the Fusobacterium nucleatum-driven host response
    • Shin J.E., et al. A periodontal pathogen Treponema denticola hijacks the Fusobacterium nucleatum-driven host response. Immunol. Cell Biol. 2013, 91:503-510.
    • (2013) Immunol. Cell Biol. , vol.91 , pp. 503-510
    • Shin, J.E.1
  • 49
    • 77955883153 scopus 로고    scopus 로고
    • Complement: a key system for immune surveillance and homeostasis
    • Ricklin D., et al. Complement: a key system for immune surveillance and homeostasis. Nat. Immunol. 2010, 11:785-797.
    • (2010) Nat. Immunol. , vol.11 , pp. 785-797
    • Ricklin, D.1
  • 50
    • 78049417345 scopus 로고    scopus 로고
    • Complement and periodontitis
    • Hajishengallis G. Complement and periodontitis. Biochem. Pharmacol. 2010, 80:1992-2001.
    • (2010) Biochem. Pharmacol. , vol.80 , pp. 1992-2001
    • Hajishengallis, G.1
  • 51
    • 61449091498 scopus 로고    scopus 로고
    • Interpain A, a cysteine proteinase from Prevotella intermedia, inhibits complement by degrading complement factor C3
    • Potempa M., et al. Interpain A, a cysteine proteinase from Prevotella intermedia, inhibits complement by degrading complement factor C3. PLoS Pathog. 2009, 5:e1000316.
    • (2009) PLoS Pathog. , vol.5 , pp. e1000316
    • Potempa, M.1
  • 52
    • 34249799593 scopus 로고    scopus 로고
    • Biphasic effect of gingipains from Porphyromonas gingivalis on the human complement system
    • Popadiak K., et al. Biphasic effect of gingipains from Porphyromonas gingivalis on the human complement system. J. Immunol. 2007, 178:7242-7250.
    • (2007) J. Immunol. , vol.178 , pp. 7242-7250
    • Popadiak, K.1
  • 53
    • 84857463226 scopus 로고    scopus 로고
    • A metalloproteinase karilysin present in the majority of Tannerella forsythia isolates inhibits all pathways of the complement system
    • Jusko M., et al. A metalloproteinase karilysin present in the majority of Tannerella forsythia isolates inhibits all pathways of the complement system. J. Immunol. 2012, 188:2338-2349.
    • (2012) J. Immunol. , vol.188 , pp. 2338-2349
    • Jusko, M.1
  • 54
    • 54049101495 scopus 로고    scopus 로고
    • Binding of complement inhibitor C4b-binding protein contributes to serum resistance of Porphyromonas gingivalis
    • Potempa M., et al. Binding of complement inhibitor C4b-binding protein contributes to serum resistance of Porphyromonas gingivalis. J. Immunol. 2008, 181:5537-5544.
    • (2008) J. Immunol. , vol.181 , pp. 5537-5544
    • Potempa, M.1
  • 55
    • 63149173182 scopus 로고    scopus 로고
    • Analysis of a unique interaction between the complement regulatory protein factor H and the periodontal pathogen Treponema denticola
    • McDowell J.V., et al. Analysis of a unique interaction between the complement regulatory protein factor H and the periodontal pathogen Treponema denticola. Infect. Immun. 2009, 77:1417-1425.
    • (2009) Infect. Immun. , vol.77 , pp. 1417-1425
    • McDowell, J.V.1
  • 56
    • 72249104320 scopus 로고    scopus 로고
    • Complementary Tolls in the periodontium: how periodontal bacteria modify complement and Toll-like receptor responses to prevail in the host
    • Krauss J.L., et al. Complementary Tolls in the periodontium: how periodontal bacteria modify complement and Toll-like receptor responses to prevail in the host. Periodontol. 2000 2010, 52:141-162.
    • (2010) Periodontol. 2000 , vol.52 , pp. 141-162
    • Krauss, J.L.1
  • 57
    • 77955760680 scopus 로고    scopus 로고
    • Dichotomy of gingipains action as virulence factors: from cleaving substrates with the precision of a surgeon's knife to a meat chopper-like brutal degradation of proteins
    • Guo Y., et al. Dichotomy of gingipains action as virulence factors: from cleaving substrates with the precision of a surgeon's knife to a meat chopper-like brutal degradation of proteins. Periodontol. 2000 2010, 54:15-44.
    • (2010) Periodontol. 2000 , vol.54 , pp. 15-44
    • Guo, Y.1
  • 58
    • 79251544574 scopus 로고    scopus 로고
    • The C5a receptor impairs IL-12-dependent clearance of Porphyromonas gingivalis and is required for induction of periodontal bone loss
    • Liang S., et al. The C5a receptor impairs IL-12-dependent clearance of Porphyromonas gingivalis and is required for induction of periodontal bone loss. J. Immunol. 2011, 186:869-877.
    • (2011) J. Immunol. , vol.186 , pp. 869-877
    • Liang, S.1
  • 59
    • 84924611238 scopus 로고    scopus 로고
    • Neutrophil dysfunction and host susceptibility to periodontal inflammation: Current state of knowledge
    • Sima C., Glogauer M. Neutrophil dysfunction and host susceptibility to periodontal inflammation: Current state of knowledge. Curr. Oral Health Rep. 2014, 1:95-103.
    • (2014) Curr. Oral Health Rep. , vol.1 , pp. 95-103
    • Sima, C.1    Glogauer, M.2
  • 60
    • 79951889113 scopus 로고    scopus 로고
    • How has neutrophil research improved our understanding of periodontal pathogenesis?
    • Nussbaum G., Shapira L. How has neutrophil research improved our understanding of periodontal pathogenesis?. J. Clin. Periodontol. 2011, 38:49-59.
    • (2011) J. Clin. Periodontol. , vol.38 , pp. 49-59
    • Nussbaum, G.1    Shapira, L.2
  • 61
    • 80053910254 scopus 로고    scopus 로고
    • Staphylococcus aureus biofilms: properties, regulation, and roles in human disease
    • Archer N.K., et al. Staphylococcus aureus biofilms: properties, regulation, and roles in human disease. Virulence 2011, 2:445-459.
    • (2011) Virulence , vol.2 , pp. 445-459
    • Archer, N.K.1
  • 62
    • 0036840348 scopus 로고    scopus 로고
    • Human leukocytes adhere to, penetrate, and respond to Staphylococcus aureus biofilms
    • Leid J.G., et al. Human leukocytes adhere to, penetrate, and respond to Staphylococcus aureus biofilms. Infect. Immun. 2002, 70:6339-6345.
    • (2002) Infect. Immun. , vol.70 , pp. 6339-6345
    • Leid, J.G.1
  • 63
    • 77953209789 scopus 로고    scopus 로고
    • Comparison of neutrophil functions in aggressive and chronic periodontitis
    • Ryder M.I. Comparison of neutrophil functions in aggressive and chronic periodontitis. Periodontol. 2000 2010, 53:124-137.
    • (2010) Periodontol. 2000 , vol.53 , pp. 124-137
    • Ryder, M.I.1
  • 64
    • 84905989203 scopus 로고    scopus 로고
    • Actin enables the antimicrobial action of LL-37 in the presence of microbial proteases
    • Sol A., et al. Actin enables the antimicrobial action of LL-37 in the presence of microbial proteases. J. Biol. Chem. 2014, 289:22926-22941.
    • (2014) J. Biol. Chem. , vol.289 , pp. 22926-22941
    • Sol, A.1
  • 65
    • 72449155528 scopus 로고    scopus 로고
    • Saliva enables the antimicrobial activity of LL-37 in the presence of proteases of Porphyromonas gingivalis
    • Gutner M., et al. Saliva enables the antimicrobial activity of LL-37 in the presence of proteases of Porphyromonas gingivalis. Infect. Immun. 2009, 77:5558-5563.
    • (2009) Infect. Immun. , vol.77 , pp. 5558-5563
    • Gutner, M.1
  • 66
    • 84902458366 scopus 로고    scopus 로고
    • Porphyromonas gingivalis manipulates complement and TLR signaling to uncouple bacterial clearance from inflammation and promote dysbiosis
    • Maekawa T., et al. Porphyromonas gingivalis manipulates complement and TLR signaling to uncouple bacterial clearance from inflammation and promote dysbiosis. Cell Host Microbe 2014, 15:768-778.
    • (2014) Cell Host Microbe , vol.15 , pp. 768-778
    • Maekawa, T.1
  • 67
    • 84869761067 scopus 로고    scopus 로고
    • Local complement-targeted intervention in periodontitis: proof-of-concept using a C5a receptor (CD88) antagonist
    • Abe T., et al. Local complement-targeted intervention in periodontitis: proof-of-concept using a C5a receptor (CD88) antagonist. J. Immunol. 2012, 189:5442-5448.
    • (2012) J. Immunol. , vol.189 , pp. 5442-5448
    • Abe, T.1
  • 68
    • 0027135337 scopus 로고
    • Inhibition of C3 and IgG proteolysis enhances phagocytosis of Porphyromonas gingivalis
    • Cutler C.W., et al. Inhibition of C3 and IgG proteolysis enhances phagocytosis of Porphyromonas gingivalis. J. Immunol. 1993, 151:7016-7029.
    • (1993) J. Immunol. , vol.151 , pp. 7016-7029
    • Cutler, C.W.1
  • 69
    • 0021924980 scopus 로고
    • Degradation of human immunoglobulins G and M and complement factors C3 and C5 by black-pigmented Bacteroides
    • Sundqvist G., et al. Degradation of human immunoglobulins G and M and complement factors C3 and C5 by black-pigmented Bacteroides. J. Med. Microbiol. 1985, 19:85-94.
    • (1985) J. Med. Microbiol. , vol.19 , pp. 85-94
    • Sundqvist, G.1
  • 70
    • 0024624450 scopus 로고
    • Further studies on the degradation of immunoglobulins by black-pigmented Bacteroides
    • Grenier D., et al. Further studies on the degradation of immunoglobulins by black-pigmented Bacteroides. Oral Microbiol. Immunol. 1989, 4:12-18.
    • (1989) Oral Microbiol. Immunol. , vol.4 , pp. 12-18
    • Grenier, D.1
  • 71
    • 80053928173 scopus 로고    scopus 로고
    • Cleavage of IgG1 and IgG3 by gingipain K from Porphyromonas gingivalis may compromise host defense in progressive periodontitis
    • Vincents B., et al. Cleavage of IgG1 and IgG3 by gingipain K from Porphyromonas gingivalis may compromise host defense in progressive periodontitis. FASEB J. 2011, 25:3741-3750.
    • (2011) FASEB J. , vol.25 , pp. 3741-3750
    • Vincents, B.1
  • 72
    • 0037264098 scopus 로고    scopus 로고
    • Origin and function of the cellular components in gingival crevice fluid
    • Delima A.J., Van Dyke T.E. Origin and function of the cellular components in gingival crevice fluid. Periodontol. 2000 2003, 31:55-76.
    • (2003) Periodontol. 2000 , vol.31 , pp. 55-76
    • Delima, A.J.1    Van Dyke, T.E.2
  • 73
    • 33745605778 scopus 로고    scopus 로고
    • Role of iNOS in human host defense
    • author reply 1874-1875
    • Nathan C. Role of iNOS in human host defense. Science 2006, 312:1874-1875. author reply 1874-1875.
    • (2006) Science , vol.312 , pp. 1874-1875
    • Nathan, C.1
  • 74
    • 77950187399 scopus 로고    scopus 로고
    • Microbial hijacking of complement-toll-like receptor crosstalk
    • Wang M., et al. Microbial hijacking of complement-toll-like receptor crosstalk. Sci. Signal. 2010, 3:ra11.
    • (2010) Sci. Signal. , vol.3 , pp. ra11
    • Wang, M.1
  • 75
    • 72249086451 scopus 로고    scopus 로고
    • Human Toll-like receptor 4 responses to P. gingivalis are regulated by lipid A 1- and 4'-phosphatase activities
    • Coats S.R., et al. Human Toll-like receptor 4 responses to P. gingivalis are regulated by lipid A 1- and 4'-phosphatase activities. Cell Microbiol. 2009, 11:1587-1599.
    • (2009) Cell Microbiol. , vol.11 , pp. 1587-1599
    • Coats, S.R.1
  • 76
    • 84893008134 scopus 로고    scopus 로고
    • Porphyromonas gingivalis lipid A phosphatase activity is critical for colonization and increasing the commensal load in the rabbit ligature model
    • Zenobia C., et al. Porphyromonas gingivalis lipid A phosphatase activity is critical for colonization and increasing the commensal load in the rabbit ligature model. Infect. Immun. 2014, 82:650-659.
    • (2014) Infect. Immun. , vol.82 , pp. 650-659
    • Zenobia, C.1
  • 77
    • 84905373653 scopus 로고    scopus 로고
    • Distinct lipid A moieties contribute to pathogen-induced site-specific vascular inflammation
    • Slocum C., et al. Distinct lipid A moieties contribute to pathogen-induced site-specific vascular inflammation. PLoS Pathog. 2014, 10:e1004215.
    • (2014) PLoS Pathog. , vol.10 , pp. e1004215
    • Slocum, C.1
  • 78
    • 84901310586 scopus 로고    scopus 로고
    • Mechanisms and functions of inflammasomes
    • Lamkanfi M., Dixit V.M. Mechanisms and functions of inflammasomes. Cell 2014, 157:1013-1022.
    • (2014) Cell , vol.157 , pp. 1013-1022
    • Lamkanfi, M.1    Dixit, V.M.2
  • 79
    • 84906571225 scopus 로고    scopus 로고
    • Inflammatory caspases are innate immune receptors for intracellular LPS
    • Shi J., et al. Inflammatory caspases are innate immune receptors for intracellular LPS. Nature 2014, 514:187-192.
    • (2014) Nature , vol.514 , pp. 187-192
    • Shi, J.1
  • 80
    • 84866529489 scopus 로고    scopus 로고
    • Porphyromonas gingivalis mediates inflammasome repression in polymicrobial cultures through a novel mechanism involving reduced endocytosis
    • Taxman D.J., et al. Porphyromonas gingivalis mediates inflammasome repression in polymicrobial cultures through a novel mechanism involving reduced endocytosis. J. Biol. Chem. 2012, 287:32791-32799.
    • (2012) J. Biol. Chem. , vol.287 , pp. 32791-32799
    • Taxman, D.J.1
  • 81
    • 46249103011 scopus 로고    scopus 로고
    • Role of Porphyromonas gingivalis SerB in gingival epithelial cell cytoskeletal remodeling and cytokine production
    • Hasegawa Y., et al. Role of Porphyromonas gingivalis SerB in gingival epithelial cell cytoskeletal remodeling and cytokine production. Infect. Immun. 2008, 76:2420-2427.
    • (2008) Infect. Immun. , vol.76 , pp. 2420-2427
    • Hasegawa, Y.1
  • 82
    • 84876408419 scopus 로고    scopus 로고
    • 'Blooming' in the gut: how dysbiosis might contribute to pathogen evolution
    • Stecher B., et al. 'Blooming' in the gut: how dysbiosis might contribute to pathogen evolution. Nat. Rev. Microbiol. 2013, 11:277-284.
    • (2013) Nat. Rev. Microbiol. , vol.11 , pp. 277-284
    • Stecher, B.1
  • 83
    • 77956569409 scopus 로고    scopus 로고
    • Enterobacteriaceae act in concert with the gut microbiota to induce spontaneous and maternally transmitted colitis
    • Garrett W.S., et al. Enterobacteriaceae act in concert with the gut microbiota to induce spontaneous and maternally transmitted colitis. Cell Host Microbe 2010, 8:292-300.
    • (2010) Cell Host Microbe , vol.8 , pp. 292-300
    • Garrett, W.S.1
  • 84
    • 84880931423 scopus 로고    scopus 로고
    • Functional profiling of the gut microbiome in disease-associated inflammation
    • Bornigen D., et al. Functional profiling of the gut microbiome in disease-associated inflammation. Genome Med. 2013, 5:65.
    • (2013) Genome Med. , vol.5 , pp. 65
    • Bornigen, D.1
  • 85
    • 79751496164 scopus 로고    scopus 로고
    • Perspective: alpha-bugs, their microbial partners, and the link to colon cancer
    • Sears C.L., Pardoll D.M. Perspective: alpha-bugs, their microbial partners, and the link to colon cancer. J. Infect. Dis. 2011, 203:306-311.
    • (2011) J. Infect. Dis. , vol.203 , pp. 306-311
    • Sears, C.L.1    Pardoll, D.M.2
  • 86
    • 84879338344 scopus 로고    scopus 로고
    • Compartmentalized and systemic control of tissue immunity by commensals
    • Belkaid Y., Naik S. Compartmentalized and systemic control of tissue immunity by commensals. Nat. Immunol. 2013, 14:646-653.
    • (2013) Nat. Immunol. , vol.14 , pp. 646-653
    • Belkaid, Y.1    Naik, S.2
  • 87
    • 34247891698 scopus 로고    scopus 로고
    • Immunization of Macaca fascicularis against experimental periodontitis using a vaccine containing cysteine proteases purified from Porphyromonas gingivalis
    • Page R.C., et al. Immunization of Macaca fascicularis against experimental periodontitis using a vaccine containing cysteine proteases purified from Porphyromonas gingivalis. Oral Microbiol. Immunol. 2007, 22:162-168.
    • (2007) Oral Microbiol. Immunol. , vol.22 , pp. 162-168
    • Page, R.C.1
  • 88
    • 84867887781 scopus 로고    scopus 로고
    • The keystone-pathogen hypothesis
    • Hajishengallis G., et al. The keystone-pathogen hypothesis. Nat. Rev. Microbiol. 2012, 10:717-725.
    • (2012) Nat. Rev. Microbiol. , vol.10 , pp. 717-725
    • Hajishengallis, G.1
  • 89
    • 84899761579 scopus 로고    scopus 로고
    • Metatranscriptomics of the human oral microbiome during health and disease
    • Jorth P., et al. Metatranscriptomics of the human oral microbiome during health and disease. MBio 2014, 5:e01012-e01014.
    • (2014) MBio , vol.5 , pp. e01012-e01014
    • Jorth, P.1
  • 90
    • 84904747868 scopus 로고    scopus 로고
    • The periodontal pathogen Porphyromonas gingivalis induces expression of transposases and cell death of Streptococcus mitis in a biofilm model
    • Duran-Pinedo A.E., et al. The periodontal pathogen Porphyromonas gingivalis induces expression of transposases and cell death of Streptococcus mitis in a biofilm model. Infect. Immun. 2014, 82:3374-3382.
    • (2014) Infect. Immun. , vol.82 , pp. 3374-3382
    • Duran-Pinedo, A.E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.