Actin enables the antimicrobial action of LL-37 peptide in the presence of microbial proteases

Journal of Biological Chemistry

Volumn 289, Issue 33, 2014, Pages 22926-22941

  Sol, Asaf ^a   Skvirsky, Yaniv ^a   Nashef, Rizan ^a   Zelentsova, Katya ^a   Burstyn Cohen, Tal ^a   Blotnick, Edna ^b   Muhlrad, Andras ^a   Bachrach, Gilad ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME ACTIVITY; MASS SPECTROMETRY; PROTEOLYSIS;

ANTI-MICROBIAL ACTIVITY; ANTIMICROBIAL ACTION; COMPETITION ASSAYS; HYDROPHOBIC INTERACTIONS; LIMITED PROTEOLYSIS; MICROBIAL PROTEASE; PSEUDOMONAS AERUGINOSA; STRUCTURAL PROTEINS;

PEPTIDES;

ACTIN; CATHELICIDIN ANTIMICROBIAL PEPTIDE LL 37; COFILIN; DEOXYRIBONUCLEASE I; F ACTIN; G ACTIN; GINGIPAIN R; HISTIDINE; LYSINE; PROTEINASE; ANTIMICROBIAL CATIONIC PEPTIDE; BACTERIAL PROTEIN; CAP18 LIPOPOLYSACCHARIDE-BINDING PROTEIN; PEPTIDE HYDROLASE;

ACTIN FILAMENT; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ANTIMICROBIAL ACTIVITY; ARTICLE; BACILLUS SUBTILIS; BACTERIAL STRAIN; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DRUG BINDING; ENZYME INHIBITION; GRANULATION TISSUE; HOST RESISTANCE; HUMAN; HUMAN CELL; HUMAN TISSUE; HYDROPHOBICITY; IMMUNOFLUORESCENCE; IMMUNOMODULATION; IONIC STRENGTH; MASS SPECTROMETRY; NUCLEOTIDE SEQUENCE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PORPHYROMONAS GINGIVALIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CLEAVAGE; PROTEIN CROSS LINKING; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; PSEUDOMONAS AERUGINOSA; TISSUE REPAIR; BACTEROIDACEAE INFECTION; CHEMISTRY; ENZYMOLOGY; FEMALE; MALE; METABOLISM; PATHOLOGY; PROTEIN SECONDARY STRUCTURE; PSEUDOMONAS INFECTION;

ACTINS; ANTIMICROBIAL CATIONIC PEPTIDES; BACTERIAL PROTEINS; BACTEROIDACEAE INFECTIONS; FEMALE; HUMANS; MALE; PEPTIDE HYDROLASES; PORPHYROMONAS GINGIVALIS; PROTEIN STRUCTURE, SECONDARY; PROTEOLYSIS; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS;

EID: 84905989203     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.579672     Document Type: Article

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