Local Chemokine Paralysis, a Novel Pathogenic Mechanism for Porphyromonas gingivalis

Infection and Immunity

Volumn 66, Issue 4, 1998, Pages 1660-1665

  Darveau, Richard P ^a,b   Belton, Carol M ^b   Reife, Robert A ^a   Lamont, Richard J ^b  

^a BRISTOL MYERS SQUIBB   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 8; MESSENGER RNA;

ARTICLE; CELL STRAIN KB; DRUG ANTAGONISM; GENETICS; HUMAN; METABOLISM; MICROBIOLOGY; PATHOGENICITY; PERIODONTAL DISEASE; PORPHYROMONAS GINGIVALIS; TOOTH PLAQUE;

DENTAL PLAQUE; HUMANS; INTERLEUKIN-8; KB CELLS; PERIODONTAL DISEASES; PORPHYROMONAS GINGIVALIS; RNA, MESSENGER;

EID: 0032036517     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.66.4.1660-1665.1998     Document Type: Article

References (44)

1. Agace, W., S. Hedges, U. Andersson, J. Andersson, M. Ceska, and C. Svanborg. 1993. Selective cytokine production by epithelial cells following exposure to Escherichia coli. Infect. Immun. 61:602-609.
2. Agace, W. W., S. R. Hedges, and C. Svanborg. 1993. Interleukin-8 and the neutrophil response to mucosal gram-negative infection. J. Clin. Invest. 92: 780-785.
3. Anderson, D. C., F. C. Schmalsteig, M. J. Finegold, B. J. Hughes, R. Rothlein, L. J. Miller, S. Kohl, M. F. Tosi, R. L. Jacobs, T. C. Waldrop, A. S. Goldman, W. T. Shearer, and T. A. Springer. 1985. The severe and moderate phenotypes of heritable Mac-1, LFA-1 deficiency: their quantitative definition and relation to leukocyte dysfunction and clinical features. J. Infect. Dis. 152:668-689.
4. Barkocy-Gallagher, G. A., N. Han, J. M. Patti, J. Whitlock, A. Progulske-Fox, and M. S. Lantz. 1996. Analysis of the prtP gene encoding porphypain, a cysteine proteinase of Porphyromonas gingivalis. J. Bacteriol. 178:2734-2741.
5. Beck, J., R. Garcia, G. Heiss, P. S. Vokonas, and S. Offenbacher. 1996. Periodontal disease and cardiovascular disease. J. Periodont. 67:1123-1137.
6. Chen, Z., J. Potempa, A. Polanowski, M. Wilkstrom, and J. Travis. 1992. Purification and characterization of a 50-kDa cysteine proteinase (gingipain) from Porphyromonas gingivalis. J. Biol. Chem. 267:18896-18901.
7. Cover, T. L., and M. J. Blaser. 1995. Helicobacter pylori: a bacterial cause of gastritis, peptic ulcer disease, and gastric cancer. ASM News 61:21-26.
8. Cutler, C. W., J. R. Kalmar, and C. A, Genco. 1995. Pathogenic strategies of the oral anaerobe, Porphyromonas gingivalis. Trends Microbiol. 3:45-51.
9. Darveau, R. P., M. D. Cunningham, T. Bailey, C. Seachord, K. Ratcliffe, B. Bainbridge, M. Dietsch, R. C. Page, and A. Aruffo. 1995. Ability of bacteria associated with chronic inflammatory disease to stimulate E-selectin expression and promote neutrophil adhesion. Infect. Immun. 63:1311-1317.
10. Darveau, R. P., and R. E. W. Hancock. 1983. Procedure for isolation of bacterial lipopolysaccharides from both smooth and rough Pseudomonas aeruginosa and Salmonella typhimurium strains. J. Bacteriol. 155:831-838.
11. Duncan, M. J., S. Nakao, Z. Skobe, and H. Xie. 1993. Interactions of Porphyromonas gingivalis with epithelial cells. Infect. Immun. 61:2260-2265.
12. Eckmann, L., M. F. Kagnoff, and J. Fierer. 1993. Epithelial cells secrete the chemokine interleukin-8 in response to bacterial entry. Infect. Immun. 61: 4569-4574.
13. Etzioni, A., M. Frydman, S. Pollack, I. Avidor, M. L. Phillips, J. C. Paulson, and R. Gershoni-Baruch. 1992. Brief report: recurrent severe infections caused by a novel leukocyte adhesion deficiency. N. Engl. J. Med. 327: 1789-1792.
14. Fletcher, J., K. Reddi, S. Poole, S. Nair, B. Henderson, P. Tabona, and M. Wilson. 1997. Interactions between periodontopathogenic bacteria and cytokines. J. Periodontal Res. 32:200-205.
15. Frey, E. A., D. S. Miller, T. G. Jahr, A. Sundan, V. Bazil, T. Espevik, B. B. Finlay, and S. D. Wright. 1992. Soluble CD14 participates in the response of cells to lipopolysaccharide. J. Exp. Med. 176:1665-1671.
16. Garcia-del Portillo, F., M. A. Stein, and B. B. Finlay. 1997. Release of lipopolysaccharide from intracellular compartments containing Salmonella typhimurium to vesicles of the host epithelial cell. Infect. Immun. 65:24-34.
17. Grayston, J. T. 1996. Chlamydia pneumoniae and atherosclerosis. Rev. Med. Interne 17:45S-47S.
18. Hillier, S. L., R. P. Nugent, D. A. Eschenbach, M. A. Krohn, R. S. Gibbs, D. H. Martin, M. F. Cotch, R. Edelman, J. G. I. Pastorek, A. V. Rao, D. McNellis, J. A. Regan, C. Carey, and M. A. Klebanoff. 1995. Association between bacterial vaginosis and preterm delivery of a low-birth-weight infant. N. Engl. J. Med. 333:1737-1742.
19. Hofstad, T., N. Skaug, and K. Sveen. 1993. Stimulation of B lymphocytes by lipopolysaccharide from anaerobic bacteria. Clin. Infect. Dis. 16:200-202.
20. Holt, S. C., J. Ebersole, J. Felton, M. Brunsvold, and K. S. Kornman. 1988. Implantation of Bacteroides gingivalis in nonhuman primates initiates progression of periodontitis. Science 239:55-57.
21. Jung, H. C., L. Eckmann, S.-K. Yang, A. Panja, J. Fierer, E. Morzycka-Wroblewska, and M. F. Kagnoff. 1995. A distinct array of proinflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion. J. Clin. Invest. 95:55-65.
22. Lament, R. J., C. A. Bevan, S. Gil, R. E. Persson, and B. Rosan. 1993. Involvement of Porphyromonas gingivalis fimbriae in adherence to Streptococcus gordonii. Oral Microbiol. Immunol. 8:272-276.
23. Lamont, R. J., A. Chan, C. M. Belton, K. T. Izutsu, D. Vasel, and A. Weinberg. 1995. Porphyromonas gingivalis invasion of gingival epithelial cells. Infect. Immun. 63:3878-3885.
24. Madianos, P. N., P. N. Papapanou, and J. Sandros. 1997. Porphyromonas gingivalis infection of oral epithelium inhibits neutrophil transepithelial migration. Infect. Immun. 65:3983-3990.
25. Malek, R., J. G. Fisher, A. Caleca, M. Stinson, C. J. van Oss, J.-Y. Lee, M.-I. Cho, R. J. Genco, R. T. Evans, and D. W. Dyer. 1994. Inactivation of the Porphyromonas gingivalis fimA gene blocks periodontal damage in gnotobiotic rats. J. Bacteriol. 176:1052-1059.
26. McCormick, B. A., P. M. Hofman, J. Kim, D. K. Carnes, S. I. Miller, and J. L. Madara. 1995. Surface attachment of Salmonella typhimurium to intestinal epithelia imprints the subepithelial matrix with gradients chemotactic for neutrophils. J. Cell Biol. 131:1599-1608.
27. Moughal, N. A., E. Adonogianaki, M. K. Thornhill, and D. F. Kinane. 1992. Endothelial cell leukocyte adhesion molecule-1 (ELAM-1) and intercellular adhesion molecule-1 (ICAM-1) expression in gingival tissue during health and experimentally-induced gingivitis. J. Periodontal Res. 27:623-630.
28. Muhlestein, J. B., E. H. Hammond, J. F. Carlquist, E. Radicke, M. J. Thomson, L. A. Karagounis, M. L. Woods, and J. L. Anderson. 1996. Increased incidence of chlamydia species within the coronary arteries of patients with symptomatic atherosclerotic versus other forms of cardiovascular disease. J. Am. Coll. Cardiol. 27:1555-1561.
29. Neidhardt, F. C., and H. E. Umbarger. 1996. Chemical composition of Escherichia coli, p. 13-16. In F. C. Neidhardt, R. Curtiss III, J. L. Ingraham, E. C. C. Lin, K. B. Low, B. Magasanik, W. S. Reznikoff, M. Riley, M. Schaechter, and H. E. Umbarger (ed.), Escherichia coli and Salmonella: cellular and molecular biology, 2nd ed. ASM Press, Washington, D.C.
30. Nylander, K., B. Danielsen, O. Fejerskov, and E. Dabelsteen. 1993. Expression of the endothelial leukocyte adhesion molecule-1 (ELAM-1) on endothelial cells in experimental gingivitis in humans. J. Periodontol. 64:355-357.
31. Offenbacher, S., V. Katz, G. Fertik, J. Collins, D. Boyd, G. Maynor, R. McKaig, and J. Beck. 1996. Periodontal infection as a risk factor for preterm low birth weight. J. Periodontol. 67:1103-1113.
32. Page, R. C., and H. E. Schroeder. 1976. Pathogenesis of inflammatory periodontal disease. A summary of current work. Lab. Invest. 33:235-249.
33. Patel, P., M. A. Mendall, D. Carrington, D. P. Strachan, E. Leatham, N. Molineaux, J. Levy, C. Blakeston, C. A. Seymour, A. J. Camm, and T. C. Northfleld. 1995. Association of Helicobacter pylori and Chlamydia pneumoniae infections with coronary heart disease and cardiovascular risk factors. Br. Med. J. 311:711-714.
34. Pugin, J., C.-C. Schurer-Maly, D. Leturcq, A. Moriarty, R. J. Ulevitch, and P. S. Tobias. 1993. Lipopolysaccharide activation of human endothelial and epithelial cells is mediated by lipopolysaccharide-binding protein and soluble CD14. Proc. Natl. Acad. Sci. USA 90:2744-2748.
35. Rasmussen, S. J., L. Eckmann, L. Shen, Y.-X. Zhang, J. Fierer, and M. F. Kagnoff. 1997. Secretion of proinflammatory cytokines by epithelial cells in response to Chlamydia infection suggests a central role for epithelial cells in chlamydial pathogenesis. J. Clin. Invest. 99:77-87.
36. Reife, R. 1996. Unpublished data.
37. Reife, R. A., R. A. Shapiro, B. A. Bamber, K. K. Berry, G. E. Mick, and R. P. Darveau. 1995. Porphyromonas gingivalis lipopolysaccharide is poorly recognized by molecular components of innate host defense in a mouse model of early inflammation. Infect. Immun. 63:4686-4694.
38. Socransky, S. S., and A. D. Haffajee. 1992. The bacterial etiology of destructive periodontal disease: current concepts. J. Periodontol. 63:322-331.
39. Tonetti, M. S. 1997. Molecular factors associated with compartmentalization of gingival immune responses and transepithelial neutrophil migration. J. Periodontal Res. 32:104-109.
40. Tonetti, M. S., M. A. Imboden, L. Gerber, N. P. Lang, J. Laisue, and C. Mueller. 1994. Localized expression of mRNA for phagocyte-specific chemotactic cytokines in human periodontal infections. Infect. Immun. 62:4005-4014.
41. Weinberg, A., C. M. Belton, Y. Park, and R. J. Lamont. 1997. Role of fimbriae in Porphyromonas gingivalis invasion of gingival epithelial cells. Infect. Immun. 65:313-316.
42. Wright, S. D. 1995. CD14 and innate recognition of bacteria. J. Immunol. 155:6-8.
43. Wright, S. D., R. A. Ramos, P. S. Tobias, R. J. Ulevitch, and J. C. Mathison. 1990. CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein. Science 249:1431-1433.
44. Yamazaki, K., and F. Ikarashi. 1992. Direct and indirect effects of Porphyromonas gingivalis lipopolysaccharide on interleukin-6 production by human gingival fibroblasts. Oral Microbiol. Immunol. 7:218-224.