Evaluation of B cell function in patients with HIV

Current Protocols in Immunology

Volumn , Issue SUPPL.100, 2013, Pages

  Buckner, Clarisa M ^a   Kardava, Lela ^a   Moir, Susan ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

B cell; CFSE; ELISPOT; HIV; Immunophenotyping; Proliferation; Subset isolation

Indexed keywords

IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M;

ARTICLE; B LYMPHOCYTE; CELL FRACTIONATION; CELL ISOLATION; ENZYME LINKED IMMUNOSPOT ASSAY; FLOW CYTOMETRY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOPHENOTYPING; LYMPHOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; LYMPHOCYTE SUBPOPULATION; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; ANIMAL; CELL SEPARATION; CIRCULATION; CULTURE TECHNIQUE; CYTOLOGY; HUMAN IMMUNODEFICIENCY VIRUS; IMMUNOCOMPROMISED PATIENT; IMMUNOLOGY; METHODOLOGY; MONONUCLEAR CELL; PHYSIOLOGY;

ANIMALS; B-LYMPHOCYTES; BLOOD CIRCULATION; CELL CULTURE TECHNIQUES; CELL SEPARATION; HIV; HIV INFECTIONS; HUMANS; IMMUNOCOMPROMISED HOST; IMMUNOPHENOTYPING; LEUKOCYTES, MONONUCLEAR; LYMPHOCYTE SUBSETS;

MLCS; MLOWN;

EID: 84880470471     PISSN: 19343671     EISSN: 1934368X     Source Type: Journal    
DOI: 10.1002/0471142735.im1213s100     Document Type: Article

References (15)

1. Akdis, M., Burgler, S., Crameri, R., Eiwegger, T., Fujita, H., Gomez, E., Klunker, S., Meyer, N., O'Mahony, L., Palomares, O., Rhyner, C., Ouaked, N., Schaffartzik, A., Van De Veen, W., Zeller, S., Zimmermann, M., and Akdis, C.A. 2011. Interleukins, from 1 to 37, and interferongamma: Receptors, functions, and roles in diseases. J. Allerg. Clin. Immunol. 127:701-721.
2. Cagigi, A., Nilsson, A., De Milito, A., and Chiodi, F. 2008. B cell immunopathology during HIV- 1 infection: Lessons to learn for HIV-1 vaccine design. Vaccine 26:3016-3025.
3. Cao, Y., Gordic, M., Kobold, S., Lajmi, N., Meyer, S., Bartels, K., Hildebrandt, Y., Luetkens, T., Ihloff, A.S., Kroger, N., Bokemeyer, C., and Atanackovic, D. 2010. An optimized assay for the enumeration of antigen-specific memory B cells in different compartments of the human body. J. Immunol. Methods 358:56-65.
4. Czerkinsky, C.C., Nilsson, L.A., Nygren, H., Ouchterlony, O., and Tarkowski, A. 1983. A solid-phase enzyme-linked immunospot (ELISPOT) assay for enumeration of specific antibody-secreting cells. J. Immunol. Methods 65:109-121.
5. Doria-Rose, N.A., Learn, G.H., Rodrigo, A.G., Nickle, D.C., Li, F., Mahalanabis, M., Hensel, M.T., McLaughlin, S., Edmonson, P.F., Montefiori, D., Barnett, S.W., Haigwood, N.L., and Mullins, J.I. 2005. Human immunodeficiency virus type 1 subtypeBancestral envelope protein is functional and elicits neutralizing antibodies in rabbits similar to those elicited by a circulating subtype B envelope. J. Virol. 79:11214- 11224.
6. Dosenovic, P., Chakrabarti, B., Soldemo, M., Douagi, I., Forsell, M.N., Li, Y., Phogat, A., Paulie, S., Hoxie, J., Wyatt, R.T., and Karlsson Hedestam, G.B. 2009. Selective expansion of HIV-1 envelope glycoprotein-specific B cell subsets recognizing distinct structural elements following immunization. J. Immunol. 183:3373- 3382.
7. Griffin, D.O., Holodick, N.E., and Rothstein, T.L. 2011. Human B1 cells in umbilical cord and adult peripheral blood express the novel phenotype CD20+ CD27+ CD43+ CD70. J. Exp. Med. 208:67-80.
8. Liao,H.X., Chen,X., Munshaw, S., Zhang, R.,Marshall, D.J., Vandergrift, N., Whitesides, J.F., Lu, X., Yu, J.S., Hwang, K.K., Gao, F., Markowitz, M., Heath, S.L., Bar, K.J., Goepfert, P.A., Montefiori, D.C., Shaw, G.C., Alam, S.M., Margolis, D.M., Denny, T.N., Boyd, S.D., Marshal, E., Egholm, M., Simen, B.B., Hanczaruk, B., Fire, A.Z., Voss, G., Kelsoe, G., Tomaras, G.D., Moody, M.A., Kepler, T.B., and Haynes, B.F. 2011. Initial antibodies binding to HIV-1 gp41 in acutely infected subjects are polyreactive and highly mutated. J. Exp. Med. 208:2237-2249.
9. Malaspina, A., Moir, S., Ho, J., Wang, W., Howell, M.L., O'Shea, M.A., Roby, G.A., Rehm, C.A., Mican, J.M., Chun, T.W., and Fauci, A.S. 2006. Appearance of immature/transitional B cells in HIV-infected individuals with advanced disease: Correlation with increased IL-7. Proc. Natl. Acad. Sci. U.S.A. 103:2262-2267.
10. Moir, S. and Fauci, A.S. 2009. B cells in HIV infection and disease. Nat. Rev. Immunol. 9:235-245.
11. Moir, S., Buckner, C.M., Ho, J., Wang, W., Chen, J., Waldner, A.J., Posada, J.G., Kardava, L., O'Shea, M.A., Kottilil, S., Chun, T.W., Proschan,M.A., and Fauci, A.S. 2010. B cells in early and chronic HIV infection: Evidence for preservation of immunefunction associated with early initiation of antiretroviral therapy. Blood 116:5571-5579.
12. Sedgwick, J.D. and Holt, P.G. 1983. A solidphase immunoenzymatic technique for the enumeration of specific antibody-secreting cells. J. Immunol. Methods 57:301-309.
13. Segundo, C., Medina, F., Rodriguez, C., Martinez- Palencia, R., Leyva-Cobian, F., and Brieva, J.A. 1999. Surface molecule loss and bleb formation by human germinal center B cells undergoing apoptosis: Role of apoptotic blebs in monocyte chemotaxis. Blood 94:1012-1020.
14. Tangye, S.G. and Tarlinton, D.M. 2009. Memory B cells: Effectors of long-lived immune responses. Eur. J. Immunol. 39:2065-2075.
15. Tomaras, G.D. and Haynes, B.F. 2009. HIV-1- specific antibody responses during acute and chronic IV-1 infection. Curr. Opin. HIV AIDS 4:373-379.