-
1
-
-
59449102796
-
Impact, mechanisms, and novel chemotherapy strategies for overcoming resistance to anthracyclines and taxanes in metastatic breast cancer
-
Perez E. Impact, mechanisms, and novel chemotherapy strategies for overcoming resistance to anthracyclines and taxanes in metastatic breast cancer. Breast Cancer Res Treat 2009; 114: 195-201.
-
(2009)
Breast Cancer Res Treat
, vol.114
, pp. 195-201
-
-
Perez, E.1
-
2
-
-
84867757134
-
Multidrug resistance in breast cancer: From in vitro models to clinical studies
-
Wind NS, Holen I. Multidrug resistance in breast cancer: from in vitro models to clinical studies. Int J Breast Cancer 2011; 2011: 1-12.
-
(2011)
Int J Breast Cancer
, vol.2011
, pp. 1-12
-
-
Wind, N.S.1
Holen, I.2
-
3
-
-
0021797892
-
Ampli fication of P-glycoprotein genes in multidrug-resistant mammalian cell lines
-
Riordan JR, Deuchars K, Kartner N, Alon N, Trent J, Ling V. Ampli fication of P-glycoprotein genes in multidrug-resistant mammalian cell lines. Nature 1985; 316: 817-819.
-
(1985)
Nature
, vol.316
, pp. 817-819
-
-
Riordan, J.R.1
Deuchars, K.2
Kartner, N.3
Alon, N.4
Trent, J.5
Ling, V.6
-
4
-
-
0031936939
-
Levels of multidrug resistance (MDR1) P-glycoprotein expression by human breast cancer correlate with in vitro resistance to taxol and doxorubicin
-
Mechetner E, Kyshtoobayeva A, Zonis S, Kim H, Stroup R, Garcia R et al. Levels of multidrug resistance (MDR1) P-glycoprotein expression by human breast cancer correlate with in vitro resistance to taxol and doxorubicin. Clin Cancer Res 1998; 4: 389-398.
-
(1998)
Clin Cancer Res
, vol.4
, pp. 389-398
-
-
Mechetner, E.1
Kyshtoobayeva, A.2
Zonis, S.3
Kim, H.4
Stroup, R.5
Garcia, R.6
-
5
-
-
0037358040
-
Overcoming multidrug resistance in cancer: An update on the clinical strategy of inhibiting P-glycoprotein
-
Hilary Thomas HMC. Overcoming multidrug resistance in cancer: an update on the clinical strategy of inhibiting P-glycoprotein. Cancer Control 2003; 10: 150-165.
-
(2003)
Cancer Control
, vol.10
, pp. 150-165
-
-
Hilary Thomas, H.M.C.1
-
6
-
-
84887992978
-
Different strategies to overcome multidrug resistance in cancer
-
Saraswathy M, Gong S. Different strategies to overcome multidrug resistance in cancer. Biotechnol Adv 2013; 31: 1397-1407.
-
(2013)
Biotechnol Adv
, vol.31
, pp. 1397-1407
-
-
Saraswathy, M.1
Gong, S.2
-
7
-
-
73949155491
-
Overcoming multidrug resistance in cancer: Clinical studies of P-glycoprotein inhibitors
-
Zhou J (eds) Humana Press: New Jersey, USA
-
Coley HM. Overcoming multidrug resistance in cancer: clinical studies of P-glycoprotein inhibitors. In: Zhou J (eds). Multi-Drug Resistance in Cancer. Humana Press: New Jersey, USA, 2010, pp 341-358.
-
(2010)
Multi-Drug Resistance in Cancer
, pp. 341-358
-
-
Coley, H.M.1
-
8
-
-
33646568511
-
Mechanisms and strategies to overcome multiple drug resistance in cancer
-
Ozben T. Mechanisms and strategies to overcome multiple drug resistance in cancer. FEBS Lett 2006; 580: 2903-2909.
-
(2006)
FEBS Lett
, vol.580
, pp. 2903-2909
-
-
Ozben, T.1
-
9
-
-
84876817977
-
P-glycoprotein inhibition as a therapeutic approach for overcoming multidrug resistance in cancer: Current status and future perspectives
-
Binkhathlan Z, Lavasanifar A. P-glycoprotein inhibition as a therapeutic approach for overcoming multidrug resistance in cancer: current status and future perspectives. Curr Cancer Drug Targets 2013; 13: 326-346.
-
(2013)
Curr Cancer Drug Targets
, vol.13
, pp. 326-346
-
-
Binkhathlan, Z.1
Lavasanifar, A.2
-
10
-
-
73949118463
-
Reversing agents for ATP-binding cassette drug transporters
-
Zhou J (eds) Humana Press: New Jersey, USA
-
Lee C. Reversing agents for ATP-binding cassette drug transporters. In: Zhou J (eds). Multi-Drug Resistance in Cancer. Humana Press: New Jersey, USA, 2010, pp 325-340.
-
(2010)
Multi-Drug Resistance in Cancer
, pp. 325-340
-
-
Lee, C.1
-
11
-
-
84871046413
-
Recent attempts at RNAi-mediated P-glycoprotein downregulation for reversal of multidrug resistance in cancer
-
Abbasi M, Lavasanifar A, Uludə H. Recent attempts at RNAi-mediated P-glycoprotein downregulation for reversal of multidrug resistance in cancer. Med Res Rev 2013; 33: 33-53.
-
(2013)
Med Res Rev
, vol.33
, pp. 33-53
-
-
Abbasi, M.1
Lavasanifar, A.2
Uludə, H.3
-
12
-
-
73949154406
-
Overcoming multidrug resistance by RNA interference
-
Zhou J (eds) Humana Press: New Jersey, USA
-
Stege A, Krühn A, Lage H. Overcoming multidrug resistance by RNA interference. In: Zhou J (eds). Multi-Drug Resistance in Cancer . Humana Press: New Jersey, USA, 2010, pp 447-465.
-
(2010)
Multi-Drug Resistance in Cancer
, pp. 447-465
-
-
Stege, A.1
Krühn, A.2
Lage, H.3
-
13
-
-
70350241634
-
Delivery of short hairpin RNAs by transkingdom RNA interference modulates the classical ABCB1-mediated multidrug-resistant phenotype of cancer cells
-
Kruehn AWA, Fruehauf J, Lage H. Delivery of short hairpin RNAs by transkingdom RNA interference modulates the classical ABCB1-mediated multidrug-resistant phenotype of cancer cells. Cell Cycle 2009; 8: 3349-3354.
-
(2009)
Cell Cycle
, vol.8
, pp. 3349-3354
-
-
Kruehn, A.W.A.1
Fruehauf, J.2
Lage, H.3
-
14
-
-
59249095556
-
Specific reversal of MDR1/P-gpdependent multidrug resistance by RNA interference in colon cancer cells
-
Xia Z, Zhu Z, Zhang L, Royal C, Liu Z, Chen Q et al. Specific reversal of MDR1/P-gpdependent multidrug resistance by RNA interference in colon cancer cells. Oncol Rep 2008; 20: 1433-1439.
-
(2008)
Oncol Rep
, vol.20
, pp. 1433-1439
-
-
Xia, Z.1
Zhu, Z.2
Zhang, L.3
Royal, C.4
Liu, Z.5
Chen, Q.6
-
15
-
-
34248682403
-
RNAi therapeutics: Principles, prospects and challenges
-
Aagaard L, Rossi JJ. RNAi therapeutics: principles, prospects and challenges. Adv Drug Deliver Rev 2007; 59: 75-86.
-
(2007)
Adv Drug Deliver Rev
, vol.59
, pp. 75-86
-
-
Aagaard, L.1
Rossi, J.J.2
-
16
-
-
69949157316
-
Missing pieces in understanding the intracellular trafficking of polycation/DNA complexes
-
Won YY, Sharma R, Konieczny SF. Missing pieces in understanding the intracellular trafficking of polycation/DNA complexes. J Control Release 2009; 139: 88-93.
-
(2009)
J Control Release
, vol.139
, pp. 88-93
-
-
Won, Y.Y.1
Sharma, R.2
Konieczny, S.F.3
-
17
-
-
84871918550
-
The possible 'proton sponge ' effect of polyethylenimine (PEI) does not include change in lysosomal pH
-
Benjaminsen RV, Mattebjerg MA, Henriksen JR, Moghimi SM, Andresen TL. The possible 'proton sponge ' effect of polyethylenimine (PEI) does not include change in lysosomal pH. Mol Ther 2013; 21: 149-157.
-
(2013)
Mol Ther
, vol.21
, pp. 149-157
-
-
Benjaminsen, R.V.1
Mattebjerg, M.A.2
Henriksen, J.R.3
Moghimi, S.M.4
Andresen, T.L.5
-
18
-
-
84868131347
-
Effects of the gene carrier polyethyleneimines on structure and function of blood components
-
Zhong D, Jiao Y, Zhang Y, Zhang W, Li N, Zuo Q et al. Effects of the gene carrier polyethyleneimines on structure and function of blood components. Biomaterials 2013; 34: 294-305.
-
(2013)
Biomaterials
, vol.34
, pp. 294-305
-
-
Zhong, D.1
Jiao, Y.2
Zhang, Y.3
Zhang, W.4
Li, N.5
Zuo, Q.6
-
19
-
-
0037437033
-
Low-molecular-weight polyethylenimine as a non-viral vector for DNA delivery: Comparison of physicochemical properties, transfection efficiency and in vivo distribution with high-molecular-weight polyethylenimine
-
Kunath K, von Harpe A, Fischer D, Petersen H, Bickel U, Voigt K et al. Low-molecular-weight polyethylenimine as a non-viral vector for DNA delivery: comparison of physicochemical properties, transfection efficiency and in vivo distribution with high-molecular-weight polyethylenimine. J Control Release 2003; 89: 113-125.
-
(2003)
J Control Release
, vol.89
, pp. 113-125
-
-
Kunath, K.1
Von Harpe, A.2
Fischer, D.3
Petersen, H.4
Bickel, U.5
Voigt, K.6
-
20
-
-
0032892476
-
Size matters: Molecular weight affects the efficiency of poly(ethylenimine) as a gene delivery vehicle
-
Godbey WT, Wu KK, Mikos AG. Size matters: molecular weight affects the efficiency of poly(ethylenimine) as a gene delivery vehicle. J Biomed Mater Res 1999; 45: 268-275.
-
(1999)
J Biomed Mater Res
, vol.45
, pp. 268-275
-
-
Godbey, W.T.1
Wu, K.K.2
Mikos, A.G.3
-
21
-
-
84555180564
-
Phospholipid- polyethylenimine conjugate-based micelle-like nanoparticles for siRNA delivery
-
Navarro G, Sawant R, Essex S, Tros de Ilarduya C, Torchilin V. Phospholipid- polyethylenimine conjugate-based micelle-like nanoparticles for siRNA delivery. Drug Deliv Transl Res 2011; 1: 25-33.
-
(2011)
Drug Deliv Transl Res
, vol.1
, pp. 25-33
-
-
Navarro, G.1
Sawant, R.2
Essex, S.3
Tros De Ilarduya, C.4
Torchilin, V.5
-
22
-
-
84555202691
-
P-glycoprotein silencing with siRNA delivered by DOPE-modified PEI overcomes doxorubicin resistance in breast cancer cells
-
Navarro G, Sawant RR, Biswas S, Essex S, Tros de Ilarduya C, Torchilin VP. P-glycoprotein silencing with siRNA delivered by DOPE-modified PEI overcomes doxorubicin resistance in breast cancer cells. Nanomedicine (Lond) 2012; 7: 65-78.
-
(2012)
Nanomedicine (Lond)
, vol.7
, pp. 65-78
-
-
Navarro, G.1
Sawant, R.R.2
Biswas, S.3
Essex, S.4
Tros De Ilarduya, C.5
Torchilin, V.P.6
-
23
-
-
79953048071
-
Tumor delivery of macromolecular drugs based on the EPR effect
-
Torchilin V. Tumor delivery of macromolecular drugs based on the EPR effect. Adv Drug Deliv Rev 2011; 63: 131-135.
-
(2011)
Adv Drug Deliv Rev
, vol.63
, pp. 131-135
-
-
Torchilin, V.1
-
24
-
-
0034993240
-
The enhanced permeability and retention (EPR) effect in tumor vasculature: The key role of tumor-selective macromolecular drug targeting
-
Maeda H. The enhanced permeability and retention (EPR) effect in tumor vasculature: the key role of tumor-selective macromolecular drug targeting. Adv Enzyme Regul 2001; 41: 189-207.
-
(2001)
Adv Enzyme Regul
, vol.41
, pp. 189-207
-
-
Maeda, H.1
-
25
-
-
60749108001
-
Polymeric drugs for efficient tumor-targeted drug delivery based on EPR-effect
-
Maeda H, Bharate GY, Daruwalla J. Polymeric drugs for efficient tumor-targeted drug delivery based on EPR-effect. Eur J Pharm Biophar 2009; 71: 409-419.
-
(2009)
Eur J Pharm Biophar
, vol.71
, pp. 409-419
-
-
Maeda, H.1
Bharate, G.Y.2
Daruwalla, J.3
-
26
-
-
84858285033
-
Polyethyleneimine-lipid conjugate-based pH-sensitive micellar carrier for gene delivery
-
Sawant RR, Sriraman SK, Navarro G, Biswas S, Dalvi RA, Torchilin VP. Polyethyleneimine-lipid conjugate-based pH-sensitive micellar carrier for gene delivery. Biomaterials 2012; 33: 3942-3951.
-
(2012)
Biomaterials
, vol.33
, pp. 3942-3951
-
-
Sawant, R.R.1
Sriraman, S.K.2
Navarro, G.3
Biswas, S.4
Dalvi, R.A.5
Torchilin, V.P.6
-
27
-
-
14644405045
-
Polymeric micelles for delivery of poorly soluble drugs: Preparation and anticancer activity in vitro of paclitaxel incorporated into mixed micelles based on poly (ethylene glycol)-lipid conjugate and positively charged lipids
-
Wang J, Mongayt D, Torchilin VP. Polymeric micelles for delivery of poorly soluble drugs: preparation and anticancer activity in vitro of paclitaxel incorporated into mixed micelles based on poly (ethylene glycol)-lipid conjugate and positively charged lipids. J Drug Target 2005; 13: 73-80.
-
(2005)
J Drug Target
, vol.13
, pp. 73-80
-
-
Wang, J.1
Mongayt, D.2
Torchilin, V.P.3
-
28
-
-
43649096714
-
Mouse 4T1 breast tumor model
-
Coligan JE, Bierer BE, Margulies DH, Shevach EM, Strober W (eds) John Wiley and Sons, Inc: New York, NY, USA
-
Pulaski BA, Ostrand-Rosenberg S. Mouse 4T1 breast tumor model. In: Coligan JE, Bierer BE, Margulies DH, Shevach EM, Strober W (eds). Current Protocols in Immunology. John Wiley and Sons, Inc: New York, NY, USA, 2001.
-
(2001)
Current Protocols in Immunology
-
-
Pulaski, B.A.1
Ostrand-Rosenberg, S.2
-
29
-
-
0037139374
-
ZD1839 (IRESSA), an EGFR-selective tyrosine kinase inhibitor, enhances taxane activity in bcl-2 overexpressing, multidrug-resistant MCF-7 ADR human breast cancer cells
-
Ciardiello F, Caputo R, Borriello G, Del Bufalo D, Biroccio A, Zupi G et al. ZD1839 (IRESSA), an EGFR-selective tyrosine kinase inhibitor, enhances taxane activity in bcl-2 overexpressing, multidrug-resistant MCF-7 ADR human breast cancer cells. Int J Cancer 2002; 98: 463-469.
-
(2002)
Int J Cancer
, vol.98
, pp. 463-469
-
-
Ciardiello, F.1
Caputo, R.2
Borriello, G.3
Del Bufalo, D.4
Biroccio, A.5
Zupi, G.6
-
30
-
-
0037089475
-
CPI-0004Na, a new extracellularly tumor-activated prodrug of doxorubicin in vivo toxicity, activity, and tissue distribution confirm tumor cell selectivity
-
Dubois V, Dasnois L, Lebtahi K, Collot F, Heylen N, Havaux N et al. CPI-0004Na, a new extracellularly tumor-activated prodrug of doxorubicin in vivo toxicity, activity, and tissue distribution confirm tumor cell selectivity. Cancer Res 2002; 62: 2327-2331.
-
(2002)
Cancer Res
, vol.62
, pp. 2327-2331
-
-
Dubois, V.1
Dasnois, L.2
Lebtahi, K.3
Collot, F.4
Heylen, N.5
Havaux, N.6
-
31
-
-
0036164671
-
The multidrug resistance of tumour cells was reversed by tetrandrine in vitro and in xenografts derived from human breast adenocarcinoma MCF-7/adr cells
-
Fu L, Zhang Y, Liang Y, Yang X, Pan Q. The multidrug resistance of tumour cells was reversed by tetrandrine in vitro and in xenografts derived from human breast adenocarcinoma MCF-7/adr cells. Eur J Cancer 2002; 38: 418-426.
-
(2002)
Eur J Cancer
, vol.38
, pp. 418-426
-
-
Fu, L.1
Zhang, Y.2
Liang, Y.3
Yang, X.4
Pan, Q.5
-
32
-
-
80054713553
-
Dendrimer phthalocyanine-encapsulated polymeric micelle-mediated photochemical internalization extends the efficacy of photodynamic therapy and overcomes drug-resistance in vivo
-
Lu H-L, Syu W-J, Nishiyama N, Kataoka K, Lai P-S. Dendrimer phthalocyanine-encapsulated polymeric micelle-mediated photochemical internalization extends the efficacy of photodynamic therapy and overcomes drug-resistance in vivo. J Control Release 2011; 155: 458-464.
-
(2011)
J Control Release
, vol.155
, pp. 458-464
-
-
Lu, H.-L.1
Syu, W.-J.2
Nishiyama, N.3
Kataoka, K.4
Lai, P.-S.5
-
33
-
-
77950657794
-
Augmentation of therapeutic efficacy in drug-resistant tumor models using ceramide coadministration in temporal-controlled polymer-blend nanoparticle delivery systems
-
van Vlerken LE, Duan Z, Little SR, Seiden MV, Amiji MM. Augmentation of therapeutic efficacy in drug-resistant tumor models using ceramide coadministration in temporal-controlled polymer-blend nanoparticle delivery systems. AAPS J 2010; 12: 171-180.
-
(2010)
AAPS J
, vol.12
, pp. 171-180
-
-
Van Vlerken, L.E.1
Duan, Z.2
Little, S.R.3
Seiden, M.V.4
Amiji, M.M.5
-
34
-
-
14844303778
-
Doxorubicin loaded pH-sensitive polymeric micelles for reversal of resistant MCF-7 tumor
-
Lee ES, Na K, Bae YH. Doxorubicin loaded pH-sensitive polymeric micelles for reversal of resistant MCF-7 tumor. J Control Release 2005; 103: 405-418.
-
(2005)
J Control Release
, vol.103
, pp. 405-418
-
-
Lee, E.S.1
Na, K.2
Bae, Y.H.3
-
35
-
-
78650302426
-
Reversal of multidrug resistance by reduction-sensitive linear cationic click polymer/iMDR1-pDNA complex nanoparticles
-
Gao Y, Chen L, Zhang Z, Chen Y, Li Y. Reversal of multidrug resistance by reduction-sensitive linear cationic click polymer/iMDR1-pDNA complex nanoparticles. Biomaterials 2011; 32: 1738-1747.
-
(2011)
Biomaterials
, vol.32
, pp. 1738-1747
-
-
Gao, Y.1
Chen, L.2
Zhang, Z.3
Chen, Y.4
Li, Y.5
-
36
-
-
77957279700
-
Sequential treatment of drug-resistant tumors with RGD-modified liposomes containing siRNA or doxorubicin
-
Jiang J, Yang S, Wang J, Yang L, Xu Z, Yang T et al. Sequential treatment of drug-resistant tumors with RGD-modified liposomes containing siRNA or doxorubicin. Eur J Pharm Biopharm 2010; 76: 170-178.
-
(2010)
Eur J Pharm Biopharm
, vol.76
, pp. 170-178
-
-
Jiang, J.1
Yang, S.2
Wang, J.3
Yang, L.4
Xu, Z.5
Yang, T.6
-
37
-
-
26244451053
-
Selection and interpretation of clinical pathology indicators of hepatic injury in preclinical studies
-
Boone L, Meyer D, Cusick P, Ennulat D, Bolliger AP, Everds N et al. Selection and interpretation of clinical pathology indicators of hepatic injury in preclinical studies. Vet Clin Pathol 2005; 34: 182-188.
-
(2005)
Vet Clin Pathol
, vol.34
, pp. 182-188
-
-
Boone, L.1
Meyer, D.2
Cusick, P.3
Ennulat, D.4
Bolliger, A.P.5
Everds, N.6
-
38
-
-
84869507166
-
Finding the optimal balance: Challenges of improving conventional cancer chemotherapy using suitable combinations with nano-sized drug delivery systems
-
Kratz F, Warnecke A. Finding the optimal balance: challenges of improving conventional cancer chemotherapy using suitable combinations with nano-sized drug delivery systems. J Control Release 2012; 164: 221-235.
-
(2012)
J Control Release
, vol.164
, pp. 221-235
-
-
Kratz, F.1
Warnecke, A.2
-
40
-
-
67650479404
-
Sequential treatment of drug-resistant tumors with targeted minicells containing siRNA or a cytotoxic drug
-
MacDiarmid JA, Amaro-Mugridge NB, Madrid-Weiss J, Sedliarou I, Wetzel S, Kochar K et al. Sequential treatment of drug-resistant tumors with targeted minicells containing siRNA or a cytotoxic drug. Nat Biotechnol 2009; 27: 643-651.
-
(2009)
Nat Biotechnol
, vol.27
, pp. 643-651
-
-
MacDiarmid, J.A.1
Amaro-Mugridge, N.B.2
Madrid-Weiss, J.3
Sedliarou, I.4
Wetzel, S.5
Kochar, K.6
-
41
-
-
84874443644
-
Codelivery of an optimal drug/siRNA combination using mesoporous silica nanoparticles to overcome drug resistance in breast cancer in vitro and in vivo
-
Meng H, Mai WX, Zhang H, Xue M, Xia T, Lin S et al. Codelivery of an optimal drug/siRNA combination using mesoporous silica nanoparticles to overcome drug resistance in breast cancer in vitro and in vivo. ACS Nano 2013; 7: 994-1005.
-
(2013)
ACS Nano
, vol.7
, pp. 994-1005
-
-
Meng, H.1
Mai, W.X.2
Zhang, H.3
Xue, M.4
Xia, T.5
Lin, S.6
-
42
-
-
58849095012
-
Evaluations of combination MDR-1 gene silencing and paclitaxel administration in biodegradable polymeric nanoparticle formulations to overcome multidrug resistance in cancer cells
-
Yadav S, van Vlerken LE, Little SR, Amiji MM. Evaluations of combination MDR-1 gene silencing and paclitaxel administration in biodegradable polymeric nanoparticle formulations to overcome multidrug resistance in cancer cells. Cancer Chemother Pharmcol 2009; 63: 711-722.
-
(2009)
Cancer Chemother Pharmcol
, vol.63
, pp. 711-722
-
-
Yadav, S.1
Van Vlerken, L.E.2
Little, S.R.3
Amiji, M.M.4
-
43
-
-
0036736888
-
Design and formulation of polyplexes based on pluronic-polyethylenimine conjugates for gene transfer
-
Gebhart CL, Sriadibhatla S, Vinogradov S, Lemieux P, Alakhov V, Kabanov AV. Design and formulation of polyplexes based on pluronic-polyethylenimine conjugates for gene transfer. Bioconjug Chem 2002; 13: 937-944.
-
(2002)
Bioconjug Chem
, vol.13
, pp. 937-944
-
-
Gebhart, C.L.1
Sriadibhatla, S.2
Vinogradov, S.3
Lemieux, P.4
Alakhov, V.5
Kabanov, A.V.6
-
44
-
-
84866182162
-
Co-delivery of paclitaxel and survivin shRNA by pluronic P85-PEI/TPGS complex nanoparticles to overcome drug resistance in lung cancer
-
Shen J, Yin Q, Chen L, Zhang Z, Li Y. Co-delivery of paclitaxel and survivin shRNA by pluronic P85-PEI/TPGS complex nanoparticles to overcome drug resistance in lung cancer. Biomaterials 2012; 33: 8613-8624.
-
(2012)
Biomaterials
, vol.33
, pp. 8613-8624
-
-
Shen, J.1
Yin, Q.2
Chen, L.3
Zhang, Z.4
Li, Y.5
-
45
-
-
77956269093
-
Nanoparticles modified with tumor-targeting scFv deliver siRNA and miRNA for cancer therapy
-
Chen Y, Zhu X, Zhang X, Liu B, Huang L. Nanoparticles modified with tumor-targeting scFv deliver siRNA and miRNA for cancer therapy. Mol Ther 2010; 18: 1650-1656.
-
(2010)
Mol Ther
, vol.18
, pp. 1650-1656
-
-
Chen, Y.1
Zhu, X.2
Zhang, X.3
Liu, B.4
Huang, L.5
-
46
-
-
46549085779
-
Local and systemic delivery of VEGF siRNA using polyelectrolyte complex micelles for effective treatment of cancer
-
Kim SH, Jeong JH, Lee SH, Kim SW, Park TG. Local and systemic delivery of VEGF siRNA using polyelectrolyte complex micelles for effective treatment of cancer. J Control Release 2008; 129: 107-116.
-
(2008)
J Control Release
, vol.129
, pp. 107-116
-
-
Kim, S.H.1
Jeong, J.H.2
Lee, S.H.3
Kim, S.W.4
Park, T.G.5
-
47
-
-
61849103493
-
In vivo pharmacokinetics, tissue distribution and underlying mechanisms of various PEI(- PEG)/siRNA complexes
-
Malek A, Merkel O, Fink L, Czubayko F, Kissel T, Aigner A. In vivo pharmacokinetics, tissue distribution and underlying mechanisms of various PEI(- PEG)/siRNA complexes. Toxicol Appl Pharm 2009; 236: 97-108.
-
(2009)
Toxicol Appl Pharm
, vol.236
, pp. 97-108
-
-
Malek, A.1
Merkel, O.2
Fink, L.3
Czubayko, F.4
Kissel, T.5
Aigner, A.6
-
48
-
-
67651202350
-
Stability of siRNA polyplexes from poly(ethylenimine) and poly(ethylenimine)-g-poly (ethylene glycol) under in vivo conditions: Effects on pharmacokinetics and biodistribution measured by Fluorescence Fluctuation Spectroscopy and Single Photon Emission Computed Tomography (SPECT) imaging
-
Merkel OM, Librizzi D, Pfestroff A, Schurrat T, Buyens K, Sanders NN et al. Stability of siRNA polyplexes from poly(ethylenimine) and poly(ethylenimine)-g-poly (ethylene glycol) under in vivo conditions: effects on pharmacokinetics and biodistribution measured by Fluorescence Fluctuation Spectroscopy and Single Photon Emission Computed Tomography (SPECT) imaging. J Control Release 2009; 138: 148-159.
-
(2009)
J Control Release
, vol.138
, pp. 148-159
-
-
Merkel, O.M.1
Librizzi, D.2
Pfestroff, A.3
Schurrat, T.4
Buyens, K.5
Sanders, N.N.6
-
49
-
-
33645148088
-
The silent treatment: SiRNAs as small molecule drugs
-
Dykxhoorn DM, Palliser D, Lieberman J. The silent treatment: siRNAs as small molecule drugs. Gene Therapy 2006; 13: 541-552.
-
(2006)
Gene Therapy
, vol.13
, pp. 541-552
-
-
Dykxhoorn, D.M.1
Palliser, D.2
Lieberman, J.3
-
50
-
-
84857438167
-
Polycation-siRNA nanoparticles can disassemble at the kidney glomerular basement membrane
-
Zuckerman JE, Choi CH, Han H, Davis ME. Polycation-siRNA nanoparticles can disassemble at the kidney glomerular basement membrane. Proc Natl Acad Sci USA 2012; 109: 3137-3142.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 3137-3142
-
-
Zuckerman, J.E.1
Choi, C.H.2
Han, H.3
Davis, M.E.4
-
51
-
-
58249091745
-
Seliciclib (CYC202, R-roscovitine) enhances the antitumor effect of doxorubicin in vivo in a breast cancer xenograft model
-
Appleyard MV, O'Neill MA, Murray KE, Paulin FE, Bray SE, Kernohan NM et al. Seliciclib (CYC202, R-roscovitine) enhances the antitumor effect of doxorubicin in vivo in a breast cancer xenograft model. Int J Cancer 2009; 124: 465-472.
-
(2009)
Int J Cancer
, vol.124
, pp. 465-472
-
-
Appleyard, M.V.1
O'Neill, M.A.2
Murray, K.E.3
Paulin, F.E.4
Bray, S.E.5
Kernohan, N.M.6
-
52
-
-
0031724078
-
Antiproliferative effect of methyl-betacyclodextrin in vitro and in human tumour xenografted athymic nude mice
-
Grosse PY, Bressolle F, Pinguet F. Antiproliferative effect of methyl-betacyclodextrin in vitro and in human tumour xenografted athymic nude mice. Br J Cancer 1998; 78: 1165-1169.
-
(1998)
Br J Cancer
, vol.78
, pp. 1165-1169
-
-
Grosse, P.Y.1
Bressolle, F.2
Pinguet, F.3
-
53
-
-
84902346219
-
A co-delivery system based on paclitaxel grafted mPEG-b-PLG loaded with doxorubicin: Preparation, in vitro and in vivo evaluation
-
Li Q, Lv S, Tang Z, Liu M, Zhang D, Yang Y et al. A co-delivery system based on paclitaxel grafted mPEG-b-PLG loaded with doxorubicin: preparation, in vitro and in vivo evaluation. Int J Pharm 2014; 471: 412-420.
-
(2014)
Int J Pharm
, vol.471
, pp. 412-420
-
-
Li, Q.1
Lv, S.2
Tang, Z.3
Liu, M.4
Zhang, D.5
Yang, Y.6
-
54
-
-
80054752836
-
siRNA-mediated down-regulation of P-glycoprotein in a Xenograft tumor model in NOD-SCID mice
-
Abbasi M, Aliabadi HM, Moase EH, Lavasanifar A, Kaur K, Lai R et al. siRNA-mediated down-regulation of P-glycoprotein in a Xenograft tumor model in NOD-SCID mice. Pharm Res 2011; 28: 2516-2529.
-
(2011)
Pharm Res
, vol.28
, pp. 2516-2529
-
-
Abbasi, M.1
Aliabadi, H.M.2
Moase, E.H.3
Lavasanifar, A.4
Kaur, K.5
Lai, R.6
-
55
-
-
84863575657
-
Overcoming multidrug resistance by co-delivery of Mdr-1 and survivin-targeting RNA with reduction-responsible cationic poly(beta-amino esters)
-
Yin Q, Shen J, Chen L, Zhang Z, Gu W, Li Y. Overcoming multidrug resistance by co-delivery of Mdr-1 and survivin-targeting RNA with reduction-responsible cationic poly(beta-amino esters). Biomaterials 2012; 33: 6495-6506.
-
(2012)
Biomaterials
, vol.33
, pp. 6495-6506
-
-
Yin, Q.1
Shen, J.2
Chen, L.3
Zhang, Z.4
Gu, W.5
Li, Y.6
-
56
-
-
70350707597
-
The use of nanoparticle-mediated targeted gene silencing and drug delivery to overcome tumor drug resistance
-
Patil YB, Swaminathan SK, Sadhukha T, Ma L, Panyam J. The use of nanoparticle-mediated targeted gene silencing and drug delivery to overcome tumor drug resistance. Biomaterials 2010; 31: 358-365.
-
(2010)
Biomaterials
, vol.31
, pp. 358-365
-
-
Patil, Y.B.1
Swaminathan, S.K.2
Sadhukha, T.3
Ma, L.4
Panyam, J.5
-
57
-
-
79959776093
-
Traceable multifunctional micellar nanocarriers for cancer-targeted co-delivery of MDR-1 siRNA and doxorubicin
-
Xiong X-B, Lavasanifar A. Traceable multifunctional micellar nanocarriers for cancer-targeted co-delivery of MDR-1 siRNA and doxorubicin. ACS Nano 2011; 5: 5202-5213.
-
(2011)
ACS Nano
, vol.5
, pp. 5202-5213
-
-
Xiong, X.-B.1
Lavasanifar, A.2
-
58
-
-
84887101220
-
Recent advances in delivery of drug-nucleic acid combinations for cancer treatment
-
Li J, Wang Y, Zhu Y, Oupicky D. Recent advances in delivery of drug-nucleic acid combinations for cancer treatment. J Control Release 2013; 172: 589-600.
-
(2013)
J Control Release
, vol.172
, pp. 589-600
-
-
Li, J.1
Wang, Y.2
Zhu, Y.3
Oupicky, D.4
-
59
-
-
0030923296
-
Disposition of conjugate-bound and free doxorubicin in tumor-bearing mice following administration of a BR96- doxorubicin immunoconjugate (BMS 182248)
-
Mosure KW, Henderson AJ, Klunk LJ, Knipe JO. Disposition of conjugate-bound and free doxorubicin in tumor-bearing mice following administration of a BR96- doxorubicin immunoconjugate (BMS 182248). Cancer Chemother Pharmcol 1997; 40: 251-258.
-
(1997)
Cancer Chemother Pharmcol
, vol.40
, pp. 251-258
-
-
Mosure, K.W.1
Henderson, A.J.2
Klunk, L.J.3
Knipe, J.O.4
-
60
-
-
33748994569
-
Influence of polyethylene glycol chain length on the physicochemical and biological properties of poly(ethylene imine)-graft-poly(ethylene glycol) block copolymer/ siRNA polyplexes
-
Mao S, Neu M, Germershaus O, Merkel O, Sitterberg J, Bakowsky U et al. Influence of polyethylene glycol chain length on the physicochemical and biological properties of poly(ethylene imine)-graft-poly(ethylene glycol) block copolymer/ siRNA polyplexes. Bioconjug Chem 2006; 17: 1209-1218.
-
(2006)
Bioconjug Chem
, vol.17
, pp. 1209-1218
-
-
Mao, S.1
Neu, M.2
Germershaus, O.3
Merkel, O.4
Sitterberg, J.5
Bakowsky, U.6
-
61
-
-
0037380839
-
Small interfering RNA-induced suppression of MDR1 (P-glycoprotein) restores sensitivity to multidrug-resistant cancer cells
-
Wu H, Hait WN, Yang J-M. Small interfering RNA-induced suppression of MDR1 (P-glycoprotein) restores sensitivity to multidrug-resistant cancer cells. Cancer Res 2003; 63 : 1515-1519.
-
(2003)
Cancer Res
, vol.63
, pp. 1515-1519
-
-
Wu, H.1
Hait, W.N.2
Yang, J.-M.3
-
62
-
-
0037336279
-
Simultaneous modulation of multidrug resistance and antiapoptotic cellular defense by MDR1 and BCL-2 targeted antisense oligonucleotides enhances the anticancer efficacy of doxorubicin
-
Pakunlu RI, Cook TJ, Minko T. Simultaneous modulation of multidrug resistance and antiapoptotic cellular defense by MDR1 and BCL-2 targeted antisense oligonucleotides enhances the anticancer efficacy of doxorubicin. Pharm Res 2003; 20 : 351-359.
-
(2003)
Pharm Res
, vol.20
, pp. 351-359
-
-
Pakunlu, R.I.1
Cook, T.J.2
Minko, T.3
-
63
-
-
57149142257
-
Co-delivery of siRNA and an anticancer drug for treatment of multidrug-resistant cancer
-
Saad M, Garbuzenko OB, Minko T. Co-delivery of siRNA and an anticancer drug for treatment of multidrug-resistant cancer. Nanomedicine (Lond) 2008; 3: 761-776.
-
(2008)
Nanomedicine (Lond)
, vol.3
, pp. 761-776
-
-
Saad, M.1
Garbuzenko, O.B.2
Minko, T.3
-
64
-
-
37549004351
-
Tumor-targeted delivery of siRNA by self-assembled nanoparticles
-
Li S-D, Chen Y-C, Hackett MJ, Huang L. Tumor-targeted delivery of siRNA by self-assembled nanoparticles. Mol Ther 2007; 16: 163-169.
-
(2007)
Mol Ther
, vol.16
, pp. 163-169
-
-
Li, S.-D.1
Chen, Y.-C.2
Hackett, M.J.3
Huang, L.4
|