Reversal of multidrug resistance by reduction-sensitive linear cationic click polymer/iMDR1-pDNA complex nanoparticles

Biomaterials

Volumn 32, Issue 6, 2011, Pages 1738-1747

  Gao, Yu ^a   Chen, Lingli ^a   Zhang, Zhiwen ^a   Chen, Yi ^a   Li, Yaping ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Click chemistry; Disulfide bond; Multidrug resistance; P glycoprotein; RNA interference

Indexed keywords

CLICK CHEMISTRY; DISULFIDE BONDS; MULTIDRUG RESISTANCE; P-GLYCOPROTEIN; RNA INTERFERENCE;

AMIDES; CYTOTOXICITY; FUNCTIONAL GROUPS; GENE EXPRESSION; GENE THERAPY; GENE TRANSFER; GLYCOPROTEINS; NANOPARTICLES; RNA;

CHEMICAL RESISTANCE;

AMIDE; DOXORUBICIN; GLYCOPROTEIN P; MULTIDRUG RESISTANCE PROTEIN 1; NANOPARTICLE; PLASMID DNA; POLYMER; TRIAZOLE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; COMPLEX FORMATION; CONTROLLED STUDY; CYTOTOXICITY; DISSOCIATION; DISULFIDE BOND; FEMALE; GENE EXPRESSION; GENE SILENCING; GENE TARGETING; GENETIC TRANSFECTION; HUMAN; HUMAN TISSUE; IN VITRO STUDY; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PRIORITY JOURNAL; REDUCTION; RNA INTERFERENCE; SYNTHESIS; TUMOR GROWTH; XENOGRAFT;

ANIMALS; BREAST NEOPLASMS; CATIONS; CELL LINE, TUMOR; CLICK CHEMISTRY; DOXORUBICIN; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; FEMALE; HUMANS; MICE; MICE, NUDE; NANOPARTICLES; P-GLYCOPROTEIN; POLYMERS; RNA, SMALL INTERFERING; TRANSFECTION;

EID: 78650302426     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2010.11.001     Document Type: Article

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