Codelivery of an optimal drug/siRNA combination using mesoporous silica nanoparticles to overcome drug resistance in breast cancer in vitro and in vivo

ACS Nano

Volumn 7, Issue 2, 2013, Pages 994-1005

  Meng, Huan ^a   Mai, Wilson X ^a   Zhang, Haiyuan ^a   Xue, Min ^a   Xia, Tian ^a   Lin, Sijie ^a   Wang, Xiang ^a   Zhao, Yang ^a   Ji, Zhaoxia ^a   Zink, Jeffrey I ^a   Nel, Andre E ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

codelivery; heterogeneous gene knockdown; high throughput screening; mesoporous silica nanoparticle; multidrug resistance

Indexed keywords

CO DELIVERIES; GENE KNOCK DOWN; HIGH THROUGHPUT SCREENING; MESOPOROUS SILICA NANOPARTICLES; MULTIDRUG RESISTANCE;

BIOLOGICAL MATERIALS; CELL CULTURE; DISEASES; DRUG PRODUCTS; ENZYME INHIBITION; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES;

TUMORS;

DOXORUBICIN; DRUG CARRIER; NANOPARTICLE; SILICON DIOXIDE; SMALL INTERFERING RNA;

ANIMAL; ARTICLE; BREAST TUMOR; CARDIOVASCULAR SYSTEM; CELL STRAIN MCF 7; CELL TRANSFORMATION; CHEMISTRY; DRUG EFFECT; DRUG RESISTANCE; GENETICS; HUMAN; METABOLISM; MOUSE; MULTIDRUG RESISTANCE; PATHOLOGY; POROSITY;

ANIMALS; BREAST NEOPLASMS; CARDIOVASCULAR SYSTEM; CELL TRANSFORMATION, NEOPLASTIC; DOXORUBICIN; DRUG CARRIERS; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; HUMANS; MCF-7 CELLS; MICE; NANOPARTICLES; POROSITY; RNA, SMALL INTERFERING; SILICON DIOXIDE;

EID: 84874443644     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn3044066     Document Type: Article

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