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Volumn 35, Issue 10, 2015, Pages 4332-4349

Complement protein C1q modulates neurite outgrowth in vitro and spinal cord axon regeneration in vivo

Author keywords

C1q; Complement; Inflammation; Regeneration; Spinal cord injury; Sprouting

Indexed keywords

ARGINASE 1; CD11B ANTIGEN; COMPLEMENT COMPONENT C1Q; CYCLIC AMP; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; MYELIN; MYELIN ASSOCIATED GLYCOPROTEIN; MYELIN BASIC PROTEIN; NEUROMODULIN; PROTEOLIPID PROTEIN; ARG1 PROTEIN, MOUSE; ARGINASE;

EID: 84924454814     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4473-12.2015     Document Type: Article
Times cited : (44)

References (94)
  • 3
    • 9744246880 scopus 로고    scopus 로고
    • Activa-tionof complement pathways after contusion-induced spinal cord injury
    • Anderson AJ, Robert S, Huang W, Young W, Cotman CW (2004) Activa-tionof complement pathways after contusion-induced spinal cord injury. J Neurotrauma 21:1831–1846.
    • (2004) J Neurotrauma , vol.21 , pp. 1831-1846
    • Anderson, A.J.1    Robert, S.2    Huang, W.3    Young, W.4    Cotman, C.W.5
  • 4
    • 18044385761 scopus 로고    scopus 로고
    • Flow cytometric analysis of CD41-labeled platelets isolated by the rapid, one-step OptiPrep method from human blood
    • Bagamery K, Kvell K, Landau R, Graham J (2005) Flow cytometric analysis of CD41-labeled platelets isolated by the rapid, one-step OptiPrep method from human blood. Cytometry A 65:84–87.
    • (2005) Cytometry A , vol.65 , pp. 84-87
    • Bagamery, K.1    Kvell, K.2    Landau, R.3    Graham, J.4
  • 5
    • 0037104719 scopus 로고    scopus 로고
    • Long-lasting sprouting and gene expression changes inducedby the monoclonal antibody IN-1 in the adult spinal cord
    • Bareyre FM, Haudenschild B, Schwab ME (2002) Long-lasting sprouting and gene expression changes inducedby the monoclonal antibody IN-1 in the adult spinal cord. J Neurosci 22:7097–7110.
    • (2002) J Neurosci , vol.22 , pp. 7097-7110
    • Bareyre, F.M.1    Haudenschild, B.2    Schwab, M.E.3
  • 7
    • 77249125330 scopus 로고    scopus 로고
    • Quantitative analysisofcellular inflammation after traumatic spinal cord injury: Evidence for a multiphasic inflammatory response in the acute to chronic environment
    • Beck KD, Nguyen HX, Galvan MD, Salazar DL, Woodruff TM, Anderson AJ (2010) Quantitative analysisofcellular inflammation after traumatic spinal cord injury: evidence for a multiphasic inflammatory response in the acute to chronic environment. Brain 133:433–447.
    • (2010) Brain , vol.133 , pp. 433-447
    • Beck, K.D.1    Nguyen, H.X.2    Galvan, M.D.3    Salazar, D.L.4    Woodruff, T.M.5    Erson, A.J.6
  • 8
    • 84872067877 scopus 로고    scopus 로고
    • C1q-induced LRP1B and GPR6 proteins expressed early in Alzheimer disease mouse models, are essential for the C1q-mediated protection against amyloid-beta neurotoxicity
    • Benoit ME, Hernandez MX, Dinh ML, Benavente F, Vasquez O, Tenner AJ (2013) C1q-induced LRP1B and GPR6 proteins expressed early in Alzheimer disease mouse models, are essential for the C1q-mediated protection against amyloid-beta neurotoxicity. J Biol Chem 288:654–665.
    • (2013) J Biol Chem , vol.288 , pp. 654-665
    • Benoit, M.E.1    Hernandez, M.X.2    Dinh, M.L.3    Benavente, F.4    Vasquez, O.5    Tenner, A.J.6
  • 10
    • 84863686504 scopus 로고    scopus 로고
    • Reduced removal of synaptic terminals from axotomized spinal motoneurons in the absence of complement C3
    • Berg A, Zelano J, Stephan A, Thams S, Barres BA, Pekny M, Pekna M, Cull-heim S (2012) Reduced removal of synaptic terminals from axotomized spinal motoneurons in the absence of complement C3. Exp Neurol 237: 8–17.
    • (2012) Exp Neurol , vol.237 , pp. 8-17
    • Berg, A.1    Zelano, J.2    Stephan, A.3    Thams, S.4    Barres, B.A.5    Pekny, M.6    Pekna, M.7    Cull-Heim, S.8
  • 11
    • 0022645888 scopus 로고
    • Topography of choline acetyltransferase immu-noreactive neurons and fibers in the rat spinal cord
    • Borges LF, Iversen SD (1986) Topography of choline acetyltransferase immu-noreactive neurons and fibers in the rat spinal cord. Brain Res 362:140–148.
    • (1986) Brain Res , vol.362 , pp. 148
    • Borges, L.F.1    Iversen, S.D.2
  • 12
    • 0032462810 scopus 로고    scopus 로고
    • C1q knock-out mice for the study of complement deficiency in autoimmune disease
    • Botto M (1998) C1q knock-out mice for the study of complement deficiency in autoimmune disease. Exp Clin Immunogenet 15:231–234.
    • (1998) Exp Clin Immunogenet , vol.15 , pp. 231-234
    • Botto, M.1
  • 13
    • 0025911564 scopus 로고
    • The role of complement in myelin phagocytosis during PNS wallerian degeneration
    • Brück W, Friede RL (1991) The role of complement in myelin phagocytosis during PNS wallerian degeneration. J Neurol Sci 103:182–187.
    • (1991) J Neurol Sci , vol.103 , pp. 182-187
    • Brück, W.1    Friede, R.L.2
  • 14
    • 42749096670 scopus 로고    scopus 로고
    • Axonal growth therapeutics: Regeneration or sprouting or plasticity?
    • Cafferty WB, McGee AW, Strittmatter SM (2008) Axonal growth therapeutics: regeneration or sprouting or plasticity? Trends Neurosci 31:215–220.
    • (2008) Trends Neurosci , vol.31 , pp. 215-220
    • Cafferty, W.B.1    McGee, A.W.2    Strittmatter, S.M.3
  • 15
    • 77952636619 scopus 로고    scopus 로고
    • MAG and OMgp synergize with Nogo-A to restrict axonal growth and neurological recovery after spinal cord trauma
    • Cafferty WB, Duffy P, Huebner E, Strittmatter SM (2010) MAG and OMgp synergize with Nogo-A to restrict axonal growth and neurological recovery after spinal cord trauma. J Neurosci 30:6825–6837.
    • (2010) J Neurosci , vol.30 , pp. 6825-6837
    • Cafferty, W.B.1    Duffy, P.2    Huebner, E.3    Strittmatter, S.M.4
  • 16
    • 0032960457 scopus 로고    scopus 로고
    • Prior exposure to neurotrophins blocks inhibition of axonal regeneration by MAG and my-elin via a cAMP-dependent mechanism
    • Cai D, Shen Y, De Bellard M, Tang S, Filbin MT (1999) Prior exposure to neurotrophins blocks inhibition of axonal regeneration by MAG and my-elin via a cAMP-dependent mechanism. Neuron 22:89–101.
    • (1999) Neuron , vol.22 , pp. 89-101
    • Cai, D.1    Shen, Y.2    De Bellard, M.3    Tang, S.4    Filbin, M.T.5
  • 17
    • 0023896592 scopus 로고
    • Two membrane protein fractions from rat central myelin with inhibitory properties for neurite growth and fibro-blast spreading
    • Caroni P, Schwab ME (1988) Two membrane protein fractions from rat central myelin with inhibitory properties for neurite growth and fibro-blast spreading. J Cell Biol 106:1281–1288.
    • (1988) J Cell Biol , vol.106 , pp. 1281-1288
    • Caroni, P.1    Schwab, M.E.2
  • 18
    • 34249339787 scopus 로고    scopus 로고
    • Myelin-associated inhibitory signaling and strategies to overcome inhibition
    • Chaudhry N, Filbin MT (2007) Myelin-associated inhibitory signaling and strategies to overcome inhibition. J Cereb Blood Flow Metab 27:1096–1107.
    • (2007) J Cereb Blood Flow Metab , vol.27 , pp. 1096-1107
    • Chaudhry, N.1    Filbin, M.T.2
  • 20
    • 33744950091 scopus 로고    scopus 로고
    • Alzheimer disease-specific conformation of hyperphosphorylated paired helical filament-Tau is polyubiquitinated through Lys-48, Lys-11, and Lys-6 ubiquitin conjugation
    • Cripps D, Thomas SN, Jeng Y, Yang F, Davies P, Yang AJ (2006) Alzheimer disease-specific conformation of hyperphosphorylated paired helical filament-Tau is polyubiquitinated through Lys-48, Lys-11, and Lys-6 ubiquitin conjugation. J Biol Chem 281:10825–10838.
    • (2006) J Biol Chem , vol.281 , pp. 10825-10838
    • Cripps, D.1    Thomas, S.N.2    Jeng, Y.3    Yang, F.4    Davies, P.5    Yang, A.J.6
  • 21
    • 0032534678 scopus 로고    scopus 로고
    • Expression of the third component of complement, C3, in regenerating limb blastema cells of urodeles
    • Del Rio-Tsonis K, Tsonis PA, Zarkadis IK, Tsagas AG, Lambris JD (1998) Expression of the third component of complement, C3, in regenerating limb blastema cells of urodeles. J Immunol 161:6819–6824.
    • (1998) J Immunol , vol.161 , pp. 6819-6824
    • Del Rio-Tsonis, K.1    Tsonis, P.A.2    Zarkadis, I.K.3    Tsagas, A.G.4    Lambris, J.D.5
  • 22
    • 68049147011 scopus 로고    scopus 로고
    • Increased synthesis of spermidine as a result of upregulation of arginase I promotes axonal regeneration in culture and in vivo
    • Deng K, He H, Qiu J, Lorber B, Bryson JB, Filbin MT (2009) Increased synthesis of spermidine as a result of upregulation of arginase I promotes axonal regeneration in culture and in vivo. J Neurosci 29:9545–9552.
    • (2009) J Neurosci , vol.29 , pp. 9545-9552
    • Deng, K.1    He, H.2    Qiu, J.3    Lorber, B.4    Bryson, J.B.5    Filbin, M.T.6
  • 23
    • 33344457341 scopus 로고    scopus 로고
    • Activation of early components of complement targets myelin and oligodendrocytes in the aged rhesus monkey brain
    • Duce JA, Hollander W, Jaffe R, Abraham CR (2006) Activation of early components of complement targets myelin and oligodendrocytes in the aged rhesus monkey brain. Neurobiol Aging 27:633–644.
    • (2006) Neurobiol Aging , vol.27 , pp. 633-644
    • Duce, J.A.1    Hollander, W.2    Jaffe, R.3    Abraham, C.R.4
  • 25
    • 58149390112 scopus 로고    scopus 로고
    • Deficiency in complement C1q improves his-tological and functional locomotor outcome after spinal cord injury
    • Galvan MD, Luchetti S, Burgos AM, Nguyen HX, Hooshmand MJ, Hamers FP, Anderson AJ (2008) Deficiency in complement C1q improves his-tological and functional locomotor outcome after spinal cord injury. J Neurosci 28:13876–13888.
    • (2008) J Neurosci , vol.28 , pp. 13876-13888
    • Galvan, M.D.1    Luchetti, S.2    Burgos, A.M.3    Nguyen, H.X.4    Hooshmand, M.J.5    Hamers, F.P.6    Erson, A.J.7
  • 26
    • 0036179679 scopus 로고    scopus 로고
    • Myelin proteolipid protein–the first 50 years
    • Greer JM, Lees MB (2002) Myelin proteolipid protein–the first 50 years. Int J Biochem Cell Biol 34:211–215.
    • (2002) Int J Biochem Cell Biol , vol.34 , pp. 211-215
    • Greer, J.M.1    Lees, M.B.2
  • 27
    • 77957223015 scopus 로고    scopus 로고
    • Effects of C3 deficiency on inflammation and regeneration following spinal cord injury in mice
    • Guo Q, Li S, Liang Y, Zhang Y, Zhang J, Wen C, Lin S, Wang H, Su B (2010) Effects of C3 deficiency on inflammation and regeneration following spinal cord injury in mice. Neurosci Lett 485:32–36.
    • (2010) Neurosci Lett , vol.485 , pp. 32-36
    • Guo, Q.1    Li, S.2    Liang, Y.3    Zhang, Y.4    Zhang, J.5    Wen, C.6    Lin, S.7    Wang, H.8    Su, B.9
  • 28
    • 69249091013 scopus 로고    scopus 로고
    • Structural polymorphism and multifunctionality of myelin basic protein
    • Harauz G, Ladizhansky V, Boggs JM (2009) Structural polymorphism and multifunctionality of myelin basic protein. Biochemistry 48:8094–8104.
    • (2009) Biochemistry , vol.48 , pp. 8094-8104
    • Harauz, G.1    Ladizhansky, V.2    Boggs, J.M.3
  • 30
    • 10444267294 scopus 로고    scopus 로고
    • Calcium mediates bidirectional growth cone turning induced by myelin-associated glycopro-tein
    • Henley JR, Huang KH, Wang D, Poo MM (2004) Calcium mediates bidirectional growth cone turning induced by myelin-associated glycopro-tein. Neuron 44:909–916.
    • (2004) Neuron , vol.44 , pp. 909-916
    • Henley, J.R.1    Huang, K.H.2    Wang, D.3    Poo, M.M.4
  • 31
    • 77954142120 scopus 로고    scopus 로고
    • Asymmetric endocytosis and remodeling of beta1-integrin adhesions during growth cone chemorepul-sion by MAG
    • Hines JH, Abu-Rub M, Henley JR (2010) Asymmetric endocytosis and remodeling of beta1-integrin adhesions during growth cone chemorepul-sion by MAG. Nat Neurosci 13:829–837.
    • (2010) Nat Neurosci , vol.13 , pp. 829-837
    • Hines, J.H.1    Abu-Rub, M.2    Henley, J.R.3
  • 32
    • 0003807468 scopus 로고    scopus 로고
    • New York: Garland Publishing
    • Janeway C, ed (2001) Immunobiology, Ed 5. New York: Garland Publishing.
    • (2001) Immunobiology
    • Janeway, C.1
  • 33
    • 0031010008 scopus 로고    scopus 로고
    • Binding of complement component Clq to myelin oligodendrocyte glycoprotein: A novel mechanism for regulating CNS inflammation
    • Johns TG, Bernard CC (1997) Binding of complement component Clq to myelin oligodendrocyte glycoprotein: a novel mechanism for regulating CNS inflammation. Mol Immunol 34:33–38.
    • (1997) Mol Immunol , vol.34 , pp. 33-38
    • Johns, T.G.1    Bernard, C.C.2
  • 34
    • 16244384670 scopus 로고    scopus 로고
    • Inflammatory-mediated injury and repair in the traumatically injured spinal cord
    • Jones TB, McDaniel EE, Popovich PG (2005) Inflammatory-mediated injury and repair in the traumatically injured spinal cord. Curr Pharm Des 11:1223–1236.
    • (2005) Curr Pharm Des , vol.11 , pp. 1223-1236
    • Jones, T.B.1    McDaniel, E.E.2    Popovich, P.G.3
  • 37
    • 0031065202 scopus 로고    scopus 로고
    • Secreted chondroitin sulfate proteoglycan of human B cell lines binds to the complement protein C1q and inhibits complex formation of C1
    • Kirschfink M, Blase L, Engelmann S, Schwartz-Albiez R (1997) Secreted chondroitin sulfate proteoglycan of human B cell lines binds to the complement protein C1q and inhibits complex formation of C1. J Immunol 158:1324–1331.
    • (1997) J Immunol , vol.158 , pp. 1324-1331
    • Kirschfink, M.1    Blase, L.2    Engelmann, S.3    Schwartz-Albiez, R.4
  • 41
    • 4744367467 scopus 로고    scopus 로고
    • Novel roles for arginase in cell survival, regeneration, and translation in the central nervous system
    • discussion 2818S–2819S
    • Lange PS, Langley B, Lu P, Ratan RR (2004) Novel roles for arginase in cell survival, regeneration, and translation in the central nervous system. J Nutr 134:2812S–2817S; discussion 2818S–2819S.
    • (2004) J Nutr , vol.134
    • Lange, P.S.1    Langley, B.2    Lu, P.3    Ratan, R.R.4
  • 44
    • 5644259586 scopus 로고    scopus 로고
    • Comparison of myelin, axon, lipid, and immunopathology in the central nervous system of differentially myelin-compromised mutant mice: A morphological and biochemical study
    • Loers G, Aboul-Enein F, Bartsch U, Lassmann H, Schachner M (2004) Comparison of myelin, axon, lipid, and immunopathology in the central nervous system of differentially myelin-compromised mutant mice: a morphological and biochemical study. Mol Cell Neurosci 27:175–189.
    • (2004) Mol Cell Neurosci , vol.27 , pp. 175-189
    • Loers, G.1    Aboul-Enein, F.2    Bartsch, U.3    Lassmann, H.4    Schachner, M.5
  • 45
    • 0035865055 scopus 로고    scopus 로고
    • A novel role of complement: Mice deficient in the fifth component of complement (C5) exhibit impaired liver regeneration
    • Mastellos D, Papadimitriou JC, Franchini S, Tsonis PA, Lambris JD (2001) A novel role of complement: mice deficient in the fifth component of complement (C5) exhibit impaired liver regeneration. J Immunol 166: 2479–2486.
    • (2001) J Immunol , vol.166 , pp. 2479-2486
    • Mastellos, D.1    Papadimitriou, J.C.2    Franchini, S.3    Tsonis, P.A.4    Lambris, J.D.5
  • 46
    • 33644541441 scopus 로고    scopus 로고
    • Evidence that complement protein C1q interacts with C-reactive protein through its globular head region
    • McGrath FD, Brouwer MC, Arlaud GJ, Daha MR, Hack CE, Roos A (2006) Evidence that complement protein C1q interacts with C-reactive protein through its globular head region. J Immunol 176:2950–2957.
    • (2006) J Immunol , vol.176 , pp. 2950-2957
    • McGrath, F.D.1    Brouwer, M.C.2    Arlaud, G.J.3    Daha, M.R.4    Hack, C.E.5    Roos, A.6
  • 47
    • 0036864199 scopus 로고    scopus 로고
    • Structure-function studies of the receptors for complement C1q
    • McGreal E, Gasque P (2002) Structure-function studies of the receptors for complement C1q. Biochem Soc Trans 30:1010–1014.
    • (2002) Biochem Soc Trans , vol.30 , pp. 1010-1014
    • McGreal, E.1    Gasque, P.2
  • 48
    • 0028075680 scopus 로고
    • Identification of myelin-associated glycoprotein as a major myelin-derived inhibitor of neurite growth
    • McKerracher L, David S, Jackson DL, Kottis V, Dunn RJ, Braun PE (1994) Identification of myelin-associated glycoprotein as a major myelin-derived inhibitor of neurite growth. Neuron 13:805–811.
    • (1994) Neuron , vol.13 , pp. 805-811
    • McKerracher, L.1    David, S.2    Jackson, D.L.3    Kottis, V.4    Dunn, R.J.5    Braun, P.E.6
  • 49
    • 0035076597 scopus 로고    scopus 로고
    • Complement anaphylatoxin C5a neuro-protects through mitogen-activated protein kinase-dependent inhibition of caspase 3
    • Mukherjee P, Pasinetti GM (2001) Complement anaphylatoxin C5a neuro-protects through mitogen-activated protein kinase-dependent inhibition of caspase 3. J Neurochem 77:43–49.
    • (2001) J Neurochem , vol.77 , pp. 43-49
    • Mukherjee, P.1    Pasinetti, G.M.2
  • 50
    • 0028060651 scopus 로고
    • A novel role for myelin-associated glycoprotein as an inhibitor of axonal regeneration
    • Mukhopadhyay G, Doherty P, Walsh FS, Crocker PR, Filbin MT (1994) A novel role for myelin-associated glycoprotein as an inhibitor of axonal regeneration. Neuron 13:757–767.
    • (1994) Neuron , vol.13 , pp. 757-767
    • Mukhopadhyay, G.1    Doherty, P.2    Walsh, F.S.3    Crocker, P.R.4    Filbin, M.T.5
  • 52
    • 0030944415 scopus 로고    scopus 로고
    • cDNA cloning and primary structure analysis of C1qR(P), the human C1q/MBL/SPA receptor that mediates enhanced phagocytosis in vitro
    • Nepomuceno RR, Henschen-Edman AH, Burgess WH, Tenner AJ (1997) cDNA cloning and primary structure analysis of C1qR(P), the human C1q/MBL/SPA receptor that mediates enhanced phagocytosis in vitro. Immunity 6:119–129.
    • Immunity , vol.6 , pp. 119-129
    • Nepomuceno, R.R.1    Henschen-Edman, A.H.2    Burgess, W.H.3
  • 53
    • 0037071890 scopus 로고    scopus 로고
    • Regeneration of sensory axons within the injured spinal cord induced by intragan-glionic cAMP elevation
    • Neumann S, Bradke F, Tessier-Lavigne M, Basbaum AI (2002) Regeneration of sensory axons within the injured spinal cord induced by intragan-glionic cAMP elevation. Neuron 34:885–893.
    • (2002) Neuron , vol.34 , pp. 885-893
    • Neumann, S.1    Bradke, F.2    Tessier-Lavigne, M.3    Basbaum, A.I.4
  • 54
    • 28044451973 scopus 로고    scopus 로고
    • Sustaining intrinsic growth capacity of adult neurons promotes spinal cord regeneration
    • Neumann S, Skinner K, Basbaum AI (2005) Sustaining intrinsic growth capacity of adult neurons promotes spinal cord regeneration. Proc Natl Acad Sci U S A 102:16848–16852.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 16848-16852
    • Neumann, S.1    Skinner, K.2    Basbaum, A.I.3
  • 55
    • 48949116251 scopus 로고    scopus 로고
    • Characterization of early and terminal complement proteins associated with polymorphonuclear leukocytes in vitro and in vivo after spinal cord injury
    • Nguyen HX, Galvan MD, Anderson AJ (2008) Characterization of early and terminal complement proteins associated with polymorphonuclear leukocytes in vitro and in vivo after spinal cord injury. J Neuroinflammation 5:26.
    • (2008) J Neuroinflammation , vol.5 , pp. 26
    • Nguyen, H.X.1    Galvan, M.D.2    Erson, A.J.3
  • 57
    • 33646566492 scopus 로고    scopus 로고
    • Chemorepellent axon guidance molecules in spinal cord injury
    • Niclou SP, Ehlert EM, Verhaagen J (2006) Chemorepellent axon guidance molecules in spinal cord injury. J Neurotrauma 23:409–421.
    • (2006) J Neurotrauma , vol.23 , pp. 409-421
    • Niclou, S.P.1    Ehlert, E.M.2    Verhaagen, J.3
  • 58
    • 0033562337 scopus 로고    scopus 로고
    • Complement-derived anaphylatoxin C5a protects against glutamate-mediated neuro-toxicity
    • Osaka H, Mukherjee P, Aisen PS, Pasinetti GM (1999) Complement-derived anaphylatoxin C5a protects against glutamate-mediated neuro-toxicity. J Cell Biochem 73:303–311.
    • (1999) J Cell Biochem , vol.73 , pp. 303-311
    • Osaka, H.1    Mukherjee, P.2    Aisen, P.S.3    Pasinetti, G.M.4
  • 59
    • 84861200993 scopus 로고    scopus 로고
    • Acetyl-L-Carnitine treatment following spinal cord injury improves mi-tochondrial function correlated with remarkable tissue sparing and functional recovery
    • Patel SP, Sullivan PG, Lyttle TS, Magnuson DSK, Rabchevsky AG (2012) Acetyl-L-Carnitine treatment following spinal cord injury improves mi-tochondrial function correlated with remarkable tissue sparing and functional recovery. Neuroscience 210:296–307.
    • (2012) Neuroscience , vol.210 , pp. 296-307
    • Patel, S.P.1    Sullivan, P.G.2    Lyttle, T.S.3    Magnuson, D.4    Rabchevsky, A.G.5
  • 60
    • 84904730509 scopus 로고    scopus 로고
    • Complement and spinal cord injury: Traditional and non-traditional aspects of complement cascade function in the injured spinal cord microenvironment
    • Peterson SL, Anderson AJ (2014) Complement and spinal cord injury: traditional and non-traditional aspects of complement cascade function in the injured spinal cord microenvironment. Exp Neurol 258:35–47.
    • (2014) Exp Neurol , vol.258 , pp. 35-47
    • Peterson, S.L.1    Erson, A.J.2
  • 61
    • 33748802258 scopus 로고    scopus 로고
    • Complement plays an important role in spinal cord injury and represents a therapeutic target for improving recovery following trauma
    • Qiao F, Atkinson C, Song H, Pannu R, Singh I, Tomlinson S (2006) Complement plays an important role in spinal cord injury and represents a therapeutic target for improving recovery following trauma. Am J Pathol 169:1039–1047.
    • (2006) Am J Pathol , vol.169 , pp. 1039-1047
    • Qiao, F.1    Atkinson, C.2    Song, H.3    Pannu, R.4    Singh, I.5    Tomlinson, S.6
  • 62
    • 78650187073 scopus 로고    scopus 로고
    • The alternative and terminal pathways of complement mediate post-traumatic spinal cord inflammation and injury
    • Qiao F, Atkinson C, Kindy MS, Shunmugavel A, Morgan BP, Song H, Tom-linson S (2010) The alternative and terminal pathways of complement mediate post-traumatic spinal cord inflammation and injury. AmJPathol 177:3061–3070.
    • (2010) Amjpathol , vol.177 , pp. 3061-3070
    • Qiao, F.1    Atkinson, C.2    Kindy, M.S.3    Shunmugavel, A.4    Morgan, B.P.5    Song, H.6    Tom-Linson, S.7
  • 67
    • 0035006284 scopus 로고    scopus 로고
    • Structure and biology of complement protein C3, a connecting link between innate and acquired immunity
    • Sahu A, Lambris JD (2001) Structure and biology of complement protein C3, a connecting link between innate and acquired immunity. Immunol Rev 180:35–48.
    • (2001) Immunol Rev , vol.180 , pp. 35-48
    • Sahu, A.1    Lambris, J.D.2
  • 68
    • 2442693021 scopus 로고    scopus 로고
    • Myelin-, reactive glia- and scar- derived CNS axon growth inhibitors: Expression, receptor signaling, and correlation with axon regeneration
    • Sandvig A, Berry M, Barrett LB, Butt A, Logan A (2004) Myelin-, reactive glia- and scar- derived CNS axon growth inhibitors: expression, receptor signaling, and correlation with axon regeneration. Glia 46:225–251.
    • (2004) Glia , vol.46 , pp. 225-251
    • Sandvig, A.1    Berry, M.2    Barrett, L.B.3    Butt, A.4    Logan, A.5
  • 70
    • 0025017637 scopus 로고
    • Axonal regeneration in the rat spinal cord produced by an antibody against myelin-associated neurite growth inhibitors
    • Schnell L, Schwab ME (1990) Axonal regeneration in the rat spinal cord produced by an antibody against myelin-associated neurite growth inhibitors. Nature 343:269–272.
    • (1990) Nature , vol.343 , pp. 269-272
    • Schnell, L.1    Schwab, M.E.2
  • 72
    • 0029900303 scopus 로고    scopus 로고
    • Degeneration and regeneration of axons in the lesioned spinal cord
    • Schwab ME, Bartholdi D (1996) Degeneration and regeneration of axons in the lesioned spinal cord. Physiol Rev 76:319–370.
    • (1996) Physiol Rev , vol.76 , pp. 319-370
    • Schwab, M.E.1    Bartholdi, D.2
  • 73
    • 72849120050 scopus 로고    scopus 로고
    • Complement-derived anaphylatoxin C3a regulates in vitro differentiation and migration of neural progenitor cells
    • Shinjyo N, Ståhlberg A, Dragunow M, Pekny M, Pekna M (2009) Complement-derived anaphylatoxin C3a regulates in vitro differentiation and migration of neural progenitor cells. Stem Cells 27:2824–2832.
    • (2009) Stem Cells , vol.27 , pp. 2824-2832
    • Shinjyo, N.1    Ståhlberg, A.2    Dragunow, M.3    Pekny, M.4    Pekna, M.5
  • 74
    • 0742288565 scopus 로고    scopus 로고
    • Regeneration beyond the glial scar
    • Silver J, Miller JH (2004) Regeneration beyond the glial scar. Nat Rev Neu-rosci 5:146–156.
    • (2004) Nat Rev Neu-Rosci , vol.5 , pp. 146-156
    • Silver, J.1    Miller, J.H.2
  • 76
    • 34548677942 scopus 로고    scopus 로고
    • Extensive structural remodeling on the injured spinal cord revealed by phosphorylated MAP1B in sprouting axons and degenerating neurons
    • Soares S, Barnat M, Salim C, von Boxberg Y, Ravailee-Veron M, Nothias F (2007) Extensive structural remodeling on the injured spinal cord revealed by phosphorylated MAP1B in sprouting axons and degenerating neurons. Eur J Neurosci 26:1446–1461.
    • (2007) Eur J Neurosci , vol.26 , pp. 1446-1461
    • Soares, S.1    Barnat, M.2    Salim, C.3    Von Boxberg, Y.4    Ravailee-Veron, M.5    Nothias, F.6
  • 77
    • 0032483342 scopus 로고    scopus 로고
    • Conversion of neuronal growth cone responses from repul-sion to attraction by cyclic nucleotides
    • Song H, Ming G, He Z, Lehmann M, McKerracher L, Tessier-Lavigne M, Poo M (1998) Conversion of neuronal growth cone responses from repul-sion to attraction by cyclic nucleotides. Science 281:1515–1518.
    • (1998) Science , vol.281 , pp. 1515-1518
    • Song, H.1    Ming, G.2    He, Z.3    Lehmann, M.4    McKerracher, L.5    Tessier-Lavigne, M.6    Poo, M.7
  • 79
    • 80053938076 scopus 로고    scopus 로고
    • Rehabilitative training following unilateral pyramidotomy in adult rats improves forelimb func-tionin anon-task-specific way
    • Starkey ML, Bleul C, Maier IC, Schwab ME (2011) Rehabilitative training following unilateral pyramidotomy in adult rats improves forelimb func-tionin anon-task-specific way. Exp Neurol 232:81–89.
    • (2011) Exp Neurol , vol.232 , pp. 81-89
    • Starkey, M.L.1    Bleul, C.2    Maier, I.C.3    Schwab, M.E.4
  • 80
    • 38649105790 scopus 로고    scopus 로고
    • A re-assessment of the effects of a Nogo-66 receptor antagonist on regenerative growth of axons and locomotor recovery after spinal cord injury in mice
    • Steward O, Sharp K, Yee KM, Hofstadter M (2008) A re-assessment of the effects of a Nogo-66 receptor antagonist on regenerative growth of axons and locomotor recovery after spinal cord injury in mice. Exp Neurol 209:446–468.
    • (2008) Exp Neurol , vol.209 , pp. 446-468
    • Steward, O.1    Sharp, K.2    Yee, K.M.3    Hofstadter, M.4
  • 82
    • 0344393564 scopus 로고    scopus 로고
    • Interaction of the C1 complex of complement with sulfated polysaccharide and DNA probed by single molecule fluorescence microscopy
    • Tissot B, Daniel R, Place C (2003) Interaction of the C1 complex of complement with sulfated polysaccharide and DNA probed by single molecule fluorescence microscopy. Eur J Biochem 270:4714–4720.
    • (2003) Eur J Biochem , vol.270 , pp. 4714-4720
    • Tissot, B.1    Daniel, R.2    Place, C.3
  • 84
    • 0037182860 scopus 로고    scopus 로고
    • Oligodendrocyte-myelin glycoprotein is a Nogo receptor ligand that inhibits neurite outgrowth
    • Wang KC, Koprivica V, Kim JA, Sivasankaran R, Guo Y, Neve RL, He Z (2002) Oligodendrocyte-myelin glycoprotein is a Nogo receptor ligand that inhibits neurite outgrowth. Nature 417:941–944.
    • (2002) Nature , vol.417 , pp. 941-944
    • Wang, K.C.1    Koprivica, V.2    Kim, J.A.3    Sivasankaran, R.4    Guo, Y.5    Neve, R.L.6    He, Z.7
  • 85
    • 84880851472 scopus 로고    scopus 로고
    • Glial scar borders are formed by newly proliferated, elongated astrocytes that interactto corral inflammatory and fibrotic cells via STAT3-dependent mechanisms after spinal cord injury
    • Wanner IB, Anderson MA, Song B, Levine J, Fernandez A, Gray-Thompson Z, Ao Y, Sofroniew MV (2013) Glial scar borders are formed by newly proliferated, elongated astrocytes that interactto corral inflammatory and fibrotic cells via STAT3-dependent mechanisms after spinal cord injury. J Neurosci 33:12870–12886.
    • (2013) J Neurosci , vol.33 , pp. 12870-12886
    • Wanner, I.B.1    Erson, M.A.2    Song, B.3    Levine, J.4    Fernandez, A.5    Gray-Thompson, Z.6    Ao, Y.7    Sofroniew, M.V.8
  • 86
    • 85013927298 scopus 로고    scopus 로고
    • A Christopher and Dana Reeve Foundation Text and Atlas: Elsevier Science
    • Watson C, Paxinos G, Kayalioglu G (2009) The Spinal Cord: A Christopher and Dana Reeve Foundation Text and Atlas: Elsevier Science.
    • (2009) The Spinal Cord
    • Watson, C.1    Paxinos, G.2    Kayalioglu, G.3
  • 87
    • 0034804805 scopus 로고    scopus 로고
    • Nerve conduction abnormalities in aging mice deficient for myelin-associated glycoprotein
    • Weiss MD, Luciano CA, Quarles RH (2001) Nerve conduction abnormalities in aging mice deficient for myelin-associated glycoprotein. Muscle Nerve 24:1380–1387.
    • (2001) Muscle Nerve , vol.24 , pp. 1380-1387
    • Weiss, M.D.1    Luciano, C.A.2    Quarles, R.H.3
  • 88
    • 0025318287 scopus 로고
    • The growth-associated protein GAP-43 appears in dorsal root ganglion cells and in the dorsal horn of the rat spinal cord following peripheral nerve injury
    • Woolf CJ, Reynolds ML, Molander C, O’Brien C, Lindsay RM, Benowitz LI (1990) The growth-associated protein GAP-43 appears in dorsal root ganglion cells and in the dorsal horn of the rat spinal cord following peripheral nerve injury. Neuroscience 34:465–478.
    • (1990) Neuroscience , vol.34 , pp. 465-478
    • Woolf, C.J.1    Reynolds, M.L.2    Molander, C.3    O’Brien, C.4    Lindsay, R.M.5    Benowitz, L.I.6
  • 89
    • 65349171523 scopus 로고    scopus 로고
    • Inhibitory activity of myelin-associated glycopro-tein on sensory neurons is largely independent of NgR1 and NgR2 and resides within Ig-Like domains 4 and 5
    • Wörter V, Schweigreiter R, Kinzel B, Mueller M, Barske C, Böck G, Frentzel S, Bandtlow CE (2009) Inhibitory activity of myelin-associated glycopro-tein on sensory neurons is largely independent of NgR1 and NgR2 and resides within Ig-Like domains 4 and 5. PLoS One 4:e5218.
    • (2009) Plos One , vol.4
    • Wörter, V.1    Schweigreiter, R.2    Kinzel, B.3    Mueller, M.4    Barske, C.5    Böck, G.6    Frentzel, S.7    Bandtlow, C.8
  • 90
    • 0036685522 scopus 로고    scopus 로고
    • Inflammation in neurodegenerative disease–a double-edged sword
    • Wyss-Coray T, Mucke L (2002) Inflammation in neurodegenerative disease–a double-edged sword. Neuron 35:419–432.
    • (2002) Neuron , vol.35 , pp. 419-432
    • Wyss-Coray, T.1    Mucke, L.2
  • 92
    • 0032521342 scopus 로고    scopus 로고
    • Myelin-associated glycoprotein is a myelin signal that modulates the caliber of myelinated axons
    • Yin X, Crawford TO, Griffin JW, Tu Ph, Lee VM, Li C, Roder J, Trapp BD (1998) Myelin-associated glycoprotein is a myelin signal that modulates the caliber of myelinated axons. J Neurosci 18:1953–2015.
    • (1998) J Neurosci , vol.18 , pp. 1953-2015
    • Yin, X.1    Crawford, T.O.2    Griffin, J.W.3    Tu, P.4    Lee, V.M.5    Li, C.6    Roder, J.7    Trapp, B.D.8
  • 93
    • 0018182846 scopus 로고
    • Effect of age on C1q and C3 levels in human serum and their presence in colostrum
    • Yonemasu K, Kitajima H, Tanabe S, Ochi T, Shinkai H (1978) Effect of age on C1q and C3 levels in human serum and their presence in colostrum. Immunology 35:523–530.
    • (1978) Immunology , vol.35 , pp. 523-530
    • Yonemasu, K.1    Kitajima, H.2    Tanabe, S.3    Ochi, T.4    Shinkai, H.5


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