C1q-induced LRP1B and GPR6 proteins expressed early in Alzheimer disease mouse models, are essential for the C1q-mediated protection against amyloid- β neurotoxicity

Journal of Biological Chemistry

Volumn 288, Issue 1, 2013, Pages 654-665

  Benoit, Marie E ^a   Hernandez, Michael X ^a   Dinh, Minhan L ^a   Benavente, Francisca ^a   Vasquez, Osvaldo ^a   Tenner, Andrea J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER DISEASE; CAMP-RESPONSE ELEMENT-BINDING PROTEINS; CLASSICAL COMPLEMENT PATHWAY; G PROTEIN COUPLED RECEPTORS; GENE EXPRESSION ANALYSIS; IN-VITRO; IN-VIVO; MOUSE MODELS; NEURITE OUTGROWTH; NEURODEGENERATIVE; NEURONAL SURVIVAL; NEUROPROTECTION; NEUROTOXICITY;

GLYCOPROTEINS; MAMMALS; NEURODEGENERATIVE DISEASES; OLIGOMERS; PHOSPHORYLATION; TOXICITY; TRANSCRIPTION FACTORS;

NEURONS;

AMYLOID BETA PROTEIN; COMPLEMENT COMPONENT C1Q; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 6; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 1B; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; AMYLOID PLAQUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; CELL SURVIVAL; COMPLEMENT ACTIVATION; COMPLEMENT CLASSICAL PATHWAY; CONTROLLED STUDY; EMBRYO; GENE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE SILENCING; GPR6 GENE; IN VIVO STUDY; LRP1B GENE; MOUSE; NERVE FIBER GROWTH; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; TRANSCRIPTION INITIATION;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; COMPLEMENT C1Q; DISEASE MODELS, ANIMAL; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; MICE; MODELS, BIOLOGICAL; NEURODEGENERATIVE DISEASES; RATS; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, LDL; TUMOR SUPPRESSOR PROTEINS; UP-REGULATION;

MUS;

EID: 84872067877     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.400168     Document Type: Article

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