Transcriptional profiling reveals functional links between RasGrf1 and Pttg1 in pancreatic beta cells

BMC Genomics

Volumn 15, Issue 1, 2014, Pages

  Manyes, Lara ^a   Arribas, Monica ^a   Gomez, Carmela ^a   Calzada, Nuria ^a   Fernandez Medarde, Alberto ^a   Santos, Eugenio ^a  

^a CSIC   (Spain)

Author keywords

Beta cells; ERK; Pancreatic islets; Pttg1; Ras; RasGrf1; Transcriptional factors; Transcriptomics

Indexed keywords

CALCIUM; GLUCOSE; GUANINE NUCLEOTIDE EXCHANGE FACTOR; INSULIN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN RASGRF1; RAS PROTEIN; SECURIN; UNCLASSIFIED DRUG; PTTG1 PROTEIN, MOUSE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALCIUM SIGNALING; CONTROLLED STUDY; GENE EXPRESSION; GENE LOCUS; GENE REPRESSION; GENETIC TRANSCRIPTION; GLUCOSE HOMEOSTASIS; INSULIN BLOOD LEVEL; MALE; MOUSE; NONHUMAN; PANCREAS ISLET; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL FUNCTION; PHENOTYPE; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; ANIMAL; BINDING SITE; C57BL MOUSE; CELL LINEAGE; CYTOSOL; DNA MICROARRAY; ENZYMOLOGY; GENE EXPRESSION PROFILING; GENETICS; GLUCOSE TOLERANCE TEST; KNOCKOUT MOUSE; METABOLISM; MOLECULAR GENETICS; SIGNAL TRANSDUCTION;

ANIMALIA; MUS;

ANIMALS; BINDING SITES; CALCIUM; CELL LINEAGE; CYTOSOL; GENE EXPRESSION PROFILING; GENETIC LOCI; GLUCOSE TOLERANCE TEST; INSULIN-SECRETING CELLS; MALE; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOGEN-ACTIVATED PROTEIN KINASES; MOLECULAR SEQUENCE ANNOTATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHENOTYPE; PROMOTER REGIONS, GENETIC; RAS PROTEINS; RAS-GRF1; SECURIN; SIGNAL TRANSDUCTION;

EID: 84924293847     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/1471-2164-15-1019     Document Type: Article

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