Characterization of the murine pituitary tumor transforming gene (PTTG) and its promoter

Endocrinology

Volumn 141, Issue 2, 2000, Pages 763-771

  Wang, Z ^a   Melmed, S ^a  

^a CEDARS SINAI MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR SP1; TRANSCRIPTION FACTOR SP3;

ANIMAL CELL; ARTICLE; CARCINOGENESIS; CELL STRAIN 3T3; COMPLEX FORMATION; GENE AMPLIFICATION; GENE DELETION; GENETIC TRANSCRIPTION; HYPOPHYSIS TUMOR; MOUSE; NONHUMAN; ONCOGENE C MYB; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING;

EID: 0034465233     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.141.2.7294     Document Type: Article

References (32)

1. Isolation and characterization of a pituitary tumor-transforming gene (PTTG)
2. Structure, expression and function of human pituitary tumor transforming gene (PTTG)
3. A. hpttg, a human homologue of rat pttg, is overexpressed in hematopoietic neoplasms. Evidence for a transcriptional activation function of hPTTG
4. Pituitary tumor transforming gene (PTTG) expression in pituitary adenomas
5. Early involvement of estrogen-induced pituitary tumor transforming gene (PTTG1) and fibroblast growth factor (bFGF) expression in prolactinoma pathogenesis
6. Identification of a vertebrate sister-chromatid separation inhibitor involved in transformation and tumorigenesis
7. An intronless homolog of human proto-oncogene hPTTG is expressed in pituitary tumors: Evidence for hPTTG family
8. Identification of an upstream enhancer within a functional promoter of the human leukemia inhibitory factor receptor gene and its alternative promoter usage
9. Sp1 elements protect a CpG island from de novo methylation
10. Sp1 sites in the mouse aprt gene promoter are required to prevent methylation of the CpG island
11. The minimal requirements for activity in transgenic mice of hypersensitive site 3 of the beta globin locus control region
12. A dominant chromatin-opening activity in 5′ hypersensitive site 3 of the human beta-globin locus control region
13. A heterodimeric nuclear protein complex binds two palindromic sequences in the proximal enhancer of the human erbB-2 gene
14. Characterization of the human ABL promoter regions
15. Organization and analysis of the promoter region and 5′ non-coding exons of the human c-src proto-oncogene
16. Tumor suppressor genes
17. 2F: A link between the Rb tumor suppressor protein and viral oncoproteins
18. Sp-1 binds promoter elements regulated by the RB protein and Sp-1-mediated transcription is stimulated by RB coexpression
19. Functional interactions between the retinoblastoma (Rb) protein and Sp-family members: Superactivation by Rb requires amino acids necessary for growth suppression
20. Negative regulation of human c-fos expression by the retinoblastoma gene product
21. Factor-binding element in the human c-myc promoter involved in transcriptional regulation by transforming growth factor beta 1 and by the retinoblastoma gene product
22. The retinoblastoma gene product RB stimulates Sp1-mediated transcription by liberating Sp1 from a negative regulator
23. Regulation of transforming growth factor β1 gene expression by the product of the retinoblastoma-susceptibility gene
24. The retinoblastoma gene product suppresses neu oncogene-induced transformation via transcriptional repression of neu
25. Casein kinase II-mediated phosphorylation of the C terminus of Sp1 decreases its DNA binding activity
26. Dephosphorylation of Sp1 by protein phosphatase 1 is involved in the glucose-mediated activation of the acetyl-CoA carboxylase gene
27. Transcription factor Sp3 antagonizes activation of the omithine decarboxylase promoter by Sp1
28. An Sp1 binding site and the minimal promoter contribute to overexpression of the cytokeratin 18 gene in tumorigenic clones relative to that in nontumorigenic clones of a human carcinoma cell line
29. The level of a transcription factor Sp1 is correlated with the expression of EGF receptor in human gastric carcinomas
30. Developmental expression of Sp1 in the mouse