High resolution separation of recombinant monoclonal antibodies by size-exclusion ultra-high performance liquid chromatography (SE-UHPLC)

Journal of Pharmaceutical and Biomedical Analysis

Volumn 109, Issue , 2015, Pages 52-61

  Yang, Renee ^a   Tang, Yun ^a   Zhang, Bing ^a   Lu, Xuemei ^a   Liu, Alice ^a   Zhang, Yonghua Taylor ^a  

^a GENENTECH INC   (United States)

Author keywords

High pressure; Monoclonal antibodies; SE UHPLC; SEC; Theoretical plates

Indexed keywords

ABCIXIMAB; IMMUNOGLOBULIN F(AB) FRAGMENT; MONOCLONAL ANTIBODY; RECOMBINANT PROTEIN;

ARTICLE; DRUG PURIFICATION; GEL PERMEATION CHROMATOGRAPHY; HYDROPHOBICITY; MOLECULAR WEIGHT; PRESSURE; PRIORITY JOURNAL; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; COMPUTER PROGRAM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOLATION AND PURIFICATION; SIZE EXCLUSION CHROMATOGRAPHY; TEMPERATURE;

ANTIBODIES, MONOCLONAL; CHROMATOGRAPHY, GEL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; IMMUNOGLOBULIN FAB FRAGMENTS; RECOMBINANT PROTEINS; SOFTWARE; TEMPERATURE;

EID: 84924270605     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2015.02.032     Document Type: Article

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