Interlaced size exclusion liquid chromatography of monoclonal antibodies

Journal of Chromatography A

Volumn 1216, Issue 51, 2009, Pages 8904-8909

  Farnan, Dell ^a   Moreno, George Tony ^a   Stults, John ^a   Becker, Andreas ^b   Tremintin, Guillaume ^b   van Gils, Mark ^b  

^a GENENTECH INC   (United States)

^b Dionex Corporation   (United States)

Author keywords

High throughput; Monoclonal antibody; Size exclusion chromatography

Indexed keywords

DETECTION TIME; DETECTION WINDOWS; HIGH THROUGHPUT; HIGH-FLOW RATE; HIGHER WEIGHT; IS DEVELOPMENT; MOLECULAR SPECIES; PRACTICAL METHOD; SEPARATION MECHANISM; SHORT COLUMN; SIZE EXCLUSION; THROUGHPUT ENHANCEMENT; THROUGHPUT IMPROVEMENT; TRADE OFF;

ALLERGIES; CHROMATOGRAPHIC ANALYSIS; GEL PERMEATION CHROMATOGRAPHY; MERGERS AND ACQUISITIONS; MONOCLONAL ANTIBODIES; SURFACE PLASMON RESONANCE; THROUGHPUT; WINDOWS;

SIZE EXCLUSION CHROMATOGRAPHY;

MONOCLONAL ANTIBODY;

ANALYTIC METHOD; ARTICLE; ELUTION; FLOW RATE; GEL PERMEATION CHROMATOGRAPHY; MONITORING; PRIORITY JOURNAL; SEPARATION TECHNIQUE; THEORY;

ANTIBODIES, MONOCLONAL; CHROMATOGRAPHY, GEL; CHROMATOGRAPHY, LIQUID; REPRODUCIBILITY OF RESULTS; TIME FACTORS;

EID: 70450201380     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2009.10.045     Document Type: Article

References (13)

1. Rosenberg A.S. AAPS J. 8 (2006) 501
2. Snyder L.R., and Kirkland J.J. Introduction to Modern Liquid Chromatography. 2nd ed. (1979), John Wiley and Sons, New York p. 484
3. Moore J.M.R., Patapoff T.W., and Cromwell M.E.M. Biochemistry 38 (1999) 13960
4. Yu C.-M., Mun S., and Wanga N.-H.L. J. Chromatogr. A 1132 (2006) 99
5. Popovici S.T., and Schoenmakers P.J. J. Chromatogr. A 1099 (2005) 91
6. Striegel A.M. Anal. Bioanal. Chem. 390 (2008) 303
7. Pasch H., and Kilz P. Macromol. Rapid Commun. 24 (2003) 104
8. King R.C., Miller-Stein C., Magiera D., and Brann J. Rapid Commun. Mass Spectrom. 16 (2002) 43
9. Snyder L.R., and Kirkland J.J. Introduction to Modern Liquid Chromatography. 2nd ed. (1979), John Wiley and Sons, New York p. 491
10. Farnan D., Frey D.D., and Horváth Cs. Biotechnol. Prog. 13 (1997) 429
11. Quan C., Alcala E., Petovska I., Matthews D., Canova-Davis E., Taticek R., and Ma S. Anal. Biochem. 373 (2008) 179
12. Gel Filtration Chromatography with TSK-GEL Columns, Tosoh Biosciences, Montgomeryville, PA, November, 2005.
13. Q2(R1): Validation of Analytical Procedures: Text and Methodology, Incorporated 2005.