Hydroxysafflor yellow A inhibits angiogenesis of hepatocellular carcinoma via blocking ERK/MAPK and NF-κB signaling pathway in H22 tumor-bearing mice

European Journal of Pharmacology

Volumn 754, Issue , 2015, Pages 105-114

  Yang, Fangfang ^a   Li, Jingmin ^a   Zhu, Jinhui ^b   Wang, Dong ^a   Chen, Shaoshui ^a   Bai, Xianyong ^a  

^a BINZHOU MEDICAL UNIVERSITY   (China)

^b Wang Ge Zhuang Central Hospital   (China)

Author keywords

Hepatocellular carcinoma; Hydroxysafflor yellowA; NF ?B signalingpathway; Ras Raf Mek Erk pathway

Indexed keywords

ANGIOGENESIS INHIBITOR; CYCLIN D1; FIBROBLAST GROWTH FACTOR 2; HYDROXYSAFFLOR YELLOW A; I KAPPA B; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MYC PROTEIN; PROTEIN C FOS; RAF PROTEIN; SORAFENIB; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG; VASCULOTROPIN A; VASCULOTROPIN RECEPTOR 1; ANTINEOPLASTIC AGENT; CHALCONE; QUINONE DERIVATIVE;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CELL NUCLEUS; CELL PROLIFERATION; CONTROLLED STUDY; CYTOPLASM; DOWN REGULATION; DRUG MEGADOSE; GENE EXPRESSION; LIVER CELL CARCINOMA; LOW DRUG DOSE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; SPLEEN; THYMUS; TUMOR XENOGRAFT; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; CANCER TRANSPLANTATION; CARCINOMA, HEPATOCELLULAR; DRUG EFFECTS; LIVER NEOPLASMS; METABOLISM; NEOVASCULARIZATION, PATHOLOGIC; TUMOR CELL LINE; VASCULARIZATION;

ANGIOGENESIS INHIBITORS; ANIMALS; ANTINEOPLASTIC AGENTS; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CELL PROLIFERATION; CHALCONE; LIVER NEOPLASMS; MALE; MAP KINASE SIGNALING SYSTEM; MICE; NEOPLASM TRANSPLANTATION; NEOVASCULARIZATION, PATHOLOGIC; NF-KAPPA B; QUINONES;

EID: 84924215035     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2015.02.015     Document Type: Article

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