Activated hepatic stellate cells promote hepatocellular carcinoma development in immunocompetent mice

International Journal of Cancer

Volumn 129, Issue 11, 2011, Pages 2651-2661

  Zhao, Wenxiu ^a   Zhang, Lei ^a   Yin, Zhenyu ^a   Su, Weixue ^a   Ren, Guangli ^a   Zhou, Changsheng ^a   You, Junyong ^a,b   Fan, Jia ^c   Wang, Xiaomin ^a  

^a XIAMEN UNIVERSITY   (China)

^b FUJIAN MEDICAL UNIVERSITY   (China)

^c FUDAN UNIVERSITY   (China)

Author keywords

cancer therapy; hepatic stellate cells; hepatocellular carcinoma; immunosuppression

Indexed keywords

CD4 ANTIGEN; COLONY STIMULATING FACTOR 1; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1ALPHA; INTERLEUKIN 2 RECEPTOR ALPHA; INTERLEUKIN 6; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MACROPHAGE INFLAMMATORY PROTEIN 2; MONOCYTE CHEMOTACTIC PROTEIN 1; MONOCYTE CHEMOTACTIC PROTEIN 5; PROGRAMMED DEATH 1 LIGAND 1; RANTES; STROMAL CELL DERIVED FACTOR 1; TISSUE INHIBITOR OF METALLOPROTEINASE 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; APOPTOSIS; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CD4+ CD25+ T LYMPHOCYTE; CELL ACTIVATION; CELL GROWTH; CELL PROLIFERATION; CELL TRANSPLANTATION; CONTROLLED STUDY; CULTURE MEDIUM; IMMUNE DEFICIENCY; IMMUNOCOMPETENCE; IMMUNOMODULATION; IMMUNOREGULATION; IN VITRO STUDY; IN VIVO STUDY; INHIBITION KINETICS; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; LYMPHOCYTE PROLIFERATION; LYMPHOCYTIC INFILTRATION; MONONUCLEAR CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; SPLEEN; STELLATE CELL; T LYMPHOCYTE; TUMOR MICROENVIRONMENT; TUMOR VASCULARIZATION;

ANIMALS; ANTIGENS, CD274; BLOTTING, WESTERN; CARCINOMA, HEPATOCELLULAR; CELL PROLIFERATION; CELLS, CULTURED; CULTURE MEDIA, CONDITIONED; DISEASE PROGRESSION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; HEPATIC STELLATE CELLS; IMMUNOENZYME TECHNIQUES; LIVER NEOPLASMS; LYMPHOCYTE ACTIVATION; LYMPHOCYTES, TUMOR-INFILTRATING; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; SPLEEN; T-LYMPHOCYTES, REGULATORY;

EID: 79960701998     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.25920     Document Type: Article

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