Down-sizing of neuronal network activity and density of presynaptic terminals by pathological acidosis are efficiently prevented by Diminazene Aceturate

Brain, Behavior, and Immunity

Volumn 45, Issue , 2015, Pages 263-276

  de Ceglia, Roberta ^a   Chaabane, Linda ^a,c   Biffi, Emilia ^b,d   Bergamaschi, Andrea ^a   Ferrigno, Giancarlo ^b   Amadio, Stefano ^a   Del Carro, Ubaldo ^a   Mazzocchi, Nausicaa ^a   Comi, Giancarlo ^c   Bianchi, Veronica ^a   Taverna, Stefano ^d   Forti, Lia ^e   D'Adamo, Patrizia ^a   Martino, Gianvito ^a   Menegon, Andrea ^a   Muzio, Luca ^a  

^a SAN RAFFAELE HOSPITAL   (Italy)

^b POLITECNICO DI MILANO   (Italy)

^c VITA SALUTE SAN RAFFAELE UNIVERSITY   (Italy)

^d ISTITUTO ITALIANO DI TECNOLOGIA   (Italy)

^e UNIVERSITY OF INSUBRIA   (Italy)

Author keywords

ASICs; Diminazene Aceturate; MEA; MRI spectroscopy; Multiple sclerosis

Indexed keywords

ACID SENSING ION CHANNEL; DIMINAZENE ACETURATE; SODIUM ION; VESICULAR GLUTAMATE TRANSPORTER 1; VESICULAR INHIBITORY AMINO ACID TRANSPORTER; ACID SENSING ION CHANNEL BLOCKING AGENT; DIMINAZENE;

ACIDOSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AXONAL INJURY; BLOOD BRAIN BARRIER; BRAIN CELL; CELL DENSITY; CELL INFILTRATION; CISTERNA MAGNA; CONTROLLED STUDY; DEMYELINATION; DISEASE COURSE; DISEASE SEVERITY; EVOKED MUSCLE RESPONSE; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; FEMALE; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MEMBRANE CHANNEL; MOUSE; NERVE CELL NECROSIS; NERVE CELL NETWORK; NEUROPROTECTION; NEUROTRANSMISSION; NON INVASIVE PROCEDURE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OPEN FIELD TEST; PH MEASUREMENT; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SINGLE DRUG DOSE; SPIKE WAVE; SYNAPTOSOME; ANALOGS AND DERIVATIVES; ANIMAL; BRAIN; DRUG EFFECTS; METABOLISM; MYELIN SHEATH; NERVE CELL; NERVE FIBER; PATHOLOGY; PH; SYNAPTIC POTENTIAL;

ACID SENSING ION CHANNEL BLOCKERS; ACID SENSING ION CHANNELS; ACIDOSIS; ANIMALS; AXONS; BRAIN; DIMINAZENE; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; HYDROGEN-ION CONCENTRATION; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MYELIN SHEATH; NEURONS; PRESYNAPTIC TERMINALS; SYNAPTIC POTENTIALS;

EID: 84924187283     PISSN: 08891591     EISSN: 10902139     Source Type: Journal    
DOI: 10.1016/j.bbi.2014.12.003     Document Type: Article

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