A new cross-correlation algorithm for the analysis of " in vitro" neuronal network activity aimed at pharmacological studies

Journal of Neuroscience Methods

Volumn 199, Issue 2, 2011, Pages 321-327

  Biffi, E ^a   Menegon, A ^b   Regalia, G ^a   Maida, S ^b   Ferrigno, G ^a   Pedrocchi, A ^a  

^a POLITECNICO DI MILANO   (Italy)

^b SAN RAFFAELE HOSPITAL   (Italy)

Author keywords

Bicuculline; Cross correlation; GABA; Micro Electrode Arrays; Network bursts; Pharmacological studies

Indexed keywords

4 AMINOBUTYRIC ACID; BICUCULLINE;

ALGORITHM; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN ELECTROPHYSIOLOGY; COMPARATIVE STUDY; CONTROLLED STUDY; CORRELATION ANALYSIS; IN VITRO STUDY; MICROELECTRODE; MOUSE; NERVE CELL; NERVE CELL NETWORK; NERVOUS SYSTEM PARAMETERS; NETWORK BURST CORRELATION ALGORITHM; NEUROMODULATION; NONHUMAN; PHARMACOLOGICAL SCIENCE; PRIORITY JOURNAL; SENSITIVITY ANALYSIS;

ACTION POTENTIALS; ALGORITHMS; ANIMALS; CELLS, CULTURED; CEREBRAL CORTEX; ELECTROPHYSIOLOGY; MICE; MICE, INBRED STRAINS; MODELS, NEUROLOGICAL; NERVE NET; NEUROPHARMACOLOGY; SIGNAL PROCESSING, COMPUTER-ASSISTED;

EID: 79960283032     PISSN: 01650270     EISSN: 1872678X     Source Type: Journal    
DOI: 10.1016/j.jneumeth.2011.05.010     Document Type: Article

References (41)

1. Anschel D.J., Ortega E., Fisher R.S. Diazepam prophylaxis for bicuculline-induced seizures: a rat dose-response model. Neurosci Lett 2004, 356:66-68.
2. Baruchi I., Grossman D., Volman V., Towle V.L., Ben-Jacob E. Functional holography analysis: simplifying the complexity of dynamical networks. Chaos 2006, 16:015112.
3. Baruchi I., Ben-Jacob E. Towards neuro-memory-chip: imprinting multiple memories in cultured neural networks. Phys Rev E 2007, 75:050901.
4. Baruchi I., Volman V., Raichman N., Shein M., Ben-Jacob E. The emergence and properties of mutual synchronization in in vitro coupled cortical networks. Eur J Neurosci 2008, 28:1825-1835.
5. Berdondini L., Massobrio P., Chiappalone M., Tedesco M., Imfeld K., Maccione A., Gandolfo M., Koudelka-Hep M., Martinoia S. Extracellular recordings from locally dense microelectrode arrays coupled to dissociated cortical cultures. J Neurosci Methods 2009, 177:386-396.
6. Boehler M.D., Wheeler B.C., Brewer G.J. Added astroglia promote greater synapse density and higher activity in neuronal networks. Neuron Glia Biol 2007, 3:127-140.
7. Boldyreva A.A. Lanthanum potentiates GABA-activated currents in rat pyramidal neurons of CA1 hippocampal field. Bull Exp Biol Med 2005, 140:398-401.
8. Bonifazi P., Ruaro M.E., Torre V. Statistical properties of information processing in neuronal networks. Eur J Neurosci 2005, 22:2953-2964.
9. Cadotte A.J., DeMarse T.B., He P., Ding M. Causal measures of structure and plasticity in simulated and living neural networks. PLoS One 2008, 310:e3355.
10. Chen C., Chen L., Lin Y., Zeng S., Luo Q. The origin of spontaneous synchronized burst in cultured neuronal networks based on multi-electrode arrays. Biosystems 2006, 85:137-143.
11. Chiappalone M., Vato A., Tedesco M.B., Marcoli M., Davide F., Martinoia S. Networks of neurons coupled to microelectrode arrays: a neuronal sensory system for pharmacological applications. Biosens Bioelectron 2003, 18:627-634.
12. Chiappalone M., Novellino A., Vajda I., Vato A., Martinoia S., van Pelt J. Burst detection algorithms for the analysis of spatio-temporal patterns in cortical networks of neurons. Neurocomputing 2005, 65(66):653-662.
13. Chiappalone M., Bove M., Vato A., Tedesco M., Martinoia S. Dissociated cortical networks show spontaneously correlated activity patterns during in vitro development. Brain Res 2006, 1093:41-53.
14. Chiappalone M., Vato A., Berdondini L., Koudelka-Hep M., Martinoia S. Network dynamics and synchronous activity in cultured cortical neurons. Int J Neural Syst 2007, 17:87-103.
15. Chiappalone M., Massobrio P., Martinoia S. Network plasticity in cortical assemblies. Eur J Neurosci 2008, 28:221-237.
16. Esposti F., Signorini M.G. Synchronization of neurons in micro-electrode array cultures. Eur Phys J 2008, 97:547-554.
17. Eytan D., Minerbi A., Ziv N., Marom S. Dopamine-induced dispersion of correlations between action potentials in networks of cortical neurons. J Neurophysiol 2004, 92:1817-1824.
18. A receptors. J Neurophysiol 2004, 92:2789-2801.
19. Garofalo M., Nieus T., Massobrio P., Martinoia S. Evaluation of the performance of information theory-based methods and cross-correlation to estimate the functional connectivity in cortical networks. PLoS One 2009, 4:e6482.
20. Gramowski A., Stuwe S., Jugelt K., Schiffmann D., Loock J., Schroder O., Gross G.W., Weiss D.G. Detecting neurotoxicity through electrical activity changes of neuronal networks on multielectrode neurochips. ALTEX 2005, 22:414-419. (Special Issue 2).
21. Jimbo Y., Tateno T., Robinson H.P.C. Simultaneous induction of pathway-specific potentiation and depression in networks of cortical neurons. Biophys J 1999, 76:670-678.
22. Khatami D.B., Nam Y., Brewer G.J., Wheeler B.C. Effect of BIC on the spontaneous and evoked activity of patterned embryonic hippocampal neurons cultured in vitro. Proc 26th Conf IEEE 2004, 4059-4062.
23. Knox C.K. Cross-correlation functions for a neuronal model. Biophys J 1974, 14:567-582.
24. Knox C.K. Detection of neuronal interactions using correlation analysis. Trends Neurosci 1981, 4:222-225.
25. Li X., Zhou W., Zeng S., Liu M., Luo Q. Long-term recording on multi-electrode array reveals degraded inhibitory connection in neuronal network development. Biosens Bioelectron 2007, 22:1538-1543.
26. Martinoia S., Bonzano L., Chiappalone M., Tedesco M., Marcoli M., Maura G. In vitro cortical neuronal networks as a new high-sensitive system for biosensing applications. Biosens Bioelectron 2005, 20:2071-2078.
27. Morefield S.I., Keefer E.W., Chapman K.D., Gross G.W. Drug evaluations using neuronal networks cultured on microelectrode arrays. Biosens Bioelectron 2000, 15:383-396.
28. Morin F.O., Takamura Y., Tamiya E. Investigating neuronal activity with planar microelectrode arrays: achievements and new perspectives. J Biosci Bioeng 2005, 100:131-143.
29. Pasquale V., Massobrio P., Bologna L.L., Chiappalone M., Martinoia S. Self-organization and neuronal avalanches in networks of dissociated cortical neurons. Neuroscience 2008, 153:1354-1369.
30. Pasquale V., Martinoia S., Chiappalone M. A self-adapting approach for the detection of bursts and network bursts in neuronal cultures. J Comput Neurosci 2010, 29:213-229.
31. Perkel D.H., Gerstein G.L., Moore G.P. Neuronal spike trains and stochastic point processes I. The single spike train. Biophys J 1967, 7:391-418.
32. Rubinsky L., Raichman N., Baruchi I., Shein M., Lavee J., Frenk H., Ben-Jacob E. Study of hypothermia on cultured neuronal networks using multi-electrode arrays. J Neurosci Methods 2007, 60:288-293.
33. Segev R., Baruchi I., Hulata E., Ben-Jacob E. Hidden neuronal correlations in cultured networks. Phys Rev Lett 2004, 92:118102.
34. Sokal D.M., Mason R., Parker T.L. Multi-neuronal recordings reveal a differential effect of thapsigargin on bicuculline- or gabazine-induced epileptiform excitability in rat hippocampal neuronal networks. Neuropharmacology 2000, 39:2408-2417.
35. Stegenga J., Le Feber J., Marani E., Rutten W.L. Analysis of cultured neuronal networks using intraburst firing characteristics. IEEE Trans Biomed Eng 2008, 55:1382-1390.
36. Stevens C.F., Zador A.M. Input synchrony and the irregular firing of cortical neurons. Nat Neurosci 1998, 1:210-217.
37. Tateno T., Jimbo Y. Activity-dependent enhancement in the reliability of correlated spike timings in cultured cortical neurons. Biol Cybern 1999, 80:45-55.
38. Wagenaar D.A., Pine J., Potter S.M. Searching for plasticity in dissociated cortical cultures on multi-electrode arrays. J Negat Results Biomed 2006, 5:16.
39. Willumsen N. Increased throughput in ion channel drug development and exploration by automation of electrophysiology. Am Biotechol Lab 2006, 24:20-23.
40. Xiang G., Pan L., Huang L., Yu Z., Song X., Cheng J., Xing W., Zhou Y. Microelectrode array-based system for neuropharmacological applications with cortical neurons cultured in vitro. Biosens Bioelectron 2007, 22:2478-2484.
41. van Pelt J., Vajda I., Wolters P.S., Corner M.A., Ramakers G.J.A. Dynamics and plasticity in developing neuronal networks in vitro. Prog Brain Res 2005, 147:173-188.