Interaction with epithelial cells modifies airway macrophage response to ozone

American Journal of Respiratory Cell and Molecular Biology

Volumn 52, Issue 3, 2015, Pages 285-294

  Bauer, Rebecca N ^a   Müller, Loretta ^b   Brighton, Luisa E ^b,c   Duncan, Kelly E ^c,d   Jaspers, Ilona ^a,b,c  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY CHILDREN S HOSPITAL   (Switzerland)

^d FOX CHASE CANCER CENTER   (United States)

Author keywords

Airway epithelial cell; Coculture; Hyaluronic acid; Macrophage; Ozone

Indexed keywords

HYALURONIC ACID; OZONE; INTERLEUKIN 8;

A549 CELL LINE; ARTICLE; CELL INTERACTION; COCULTURE; CONTROLLED STUDY; CYTOTOXICITY; DENDRITIC CELL; EOSINOPHIL; EPITHELIUM CELL; HUMAN; HUMAN CELL; IMMUNOCOMPETENT CELL; IMMUNOPHENOTYPING; IN VITRO STUDY; IN VIVO STUDY; INNATE IMMUNITY; LUNG LAVAGE; MACROPHAGE; MONOCULTURE; NEUTROPHIL; NORMAL HUMAN; PHAGOCYTOSIS; STAPHYLOCOCCUS AUREUS; BRONCHOALVEOLAR LAVAGE FLUID; CELL LINE; IMMUNOLOGY; METABOLISM; RESPIRATORY SYSTEM; TUMOR CELL LINE;

BRONCHOALVEOLAR LAVAGE FLUID; CELL LINE; CELL LINE, TUMOR; EPITHELIAL CELLS; HUMANS; HYALURONIC ACID; INTERLEUKIN-8; MACROPHAGES; OZONE; PHAGOCYTOSIS; RESPIRATORY SYSTEM;

EID: 84924174570     PISSN: 10441549     EISSN: 15354989     Source Type: Journal    
DOI: 10.1165/rcmb.2014-0035OC     Document Type: Article

References (48)

1. Hollingsworth JW, Kleeberger SR, Foster WM. Ozone and pulmonary innate immunity. Proc Am Thorac Soc 2007; 4:240-246.
2. Centers for Disease Control and Prevention. Unhealthy air quality-United States, 2006-2009. 2011 [updated 2011 Jan 14; accessed 2012 Dec 13]. Available from: http://www.cdc.gov/mmwr/preview/mmwrhtml/su6001a5.htm
3. Bauer RN, Diaz-Sanchez D, Jaspers I. Effects of air pollutants on innate immunity: the role of Toll-like receptors and nucleotide-binding oligomerization domain-like receptors. J Allergy Clin Immunol 2012; 129:14-24; quiz 25-26.
4. Dahl M, Bauer AK, Arredouani M, Soininen R., Tryggvason K, Kleeberger SR, Kobzik L. Protection against inhaled oxidants through scavenging of oxidized lipids by macrophage receptors MARCO and SR-AI/II. J Clin Invest 2007; 117:757-764.
5. Kirichenko A, Li L, Morandi M.T., Holian A. 4-hydroxy-2-nonenal-protein adducts and apoptosis in murine lung cells after acute ozone exposure. Toxicol Appl Pharmacol 1996; 141:416-424.
6. Garantziotis S, Li Z, Potts E.N., Kimata K., Zhuo L, Morgan DL, Savani R.C., Noble PW, Foster WM, Schwartz DA, et al. Hyaluronan mediates ozone-induced airway hyperresponsiveness in mice. J Biol Chem 2009; 284:11309-11317.
7. Jiang D, Liang J, Fan J., Yu S, Chen S, Luo Y., Prestwich GD, Mascarenhas MM, Garg HG, Quinn DA, et al. Regulation of lung injury and repair by toll-like receptors and hyaluronan. Nat Med 2005; 11: 1173-1179.
8. Hernandez ML, Lay JC, Harris B, Esther CR Jr, Brickey WJ, Bromberg PA, Diaz-Sanchez D, Devlin RB, Kleeberger S.R., Alexis NE, et al. Atopic asthmatic subjects but not atopic subjects without asthma have enhanced inflammatory response to ozone. J Allergy Clin Immunol 2010; 126:537-544.e1.
9. Lohmann-Matthes ML, Steinmuller C, Franke-Ullmann G. Pulmonary macrophages. Eur Respir J 1994; 7:1678-1689.
10. Proud D, Leigh R. Epithelial cells and airway diseases. Immunol Rev 2011; 242:186-204.
11. Leikauf GD, Simpson LG, Santrock J, Zhao Q., Abbinante-Nissen J, Zhou S, Driscoll KE. Airway epithelial cell responses to ozone injury. Environ Health Perspect 1995; 103:91-95.
12. Kosmider B, Loader JE, Murphy R.C., Mason RJ. Apoptosis induced by ozone and oxysterols in human alveolar epithelial cells. Free Radic Biol Med 2010; 48:1513-1524.
13. Laskin DL, Sunil VR, Gardner C.R., Laskin JD. Macrophages and tissue injury: agents of defense or destruction? Annu Rev Pharmacol Toxicol 2011; 51:267-288.
14. Pendino KJ, Meidhof TM, Heck D.E., Laskin JD, Laskin DL. Inhibition of macrophages with gadolinium chloride abrogates ozone-induced pulmonary injury and inflammatory mediator production. Am J Respir Cell Mol Biol 1995; 13:125-132.
15. Sunil VR, Patel-Vayas K, Shen J., Laskin JD, Laskin DL. Classical and alternative macrophage activation in the lung following ozone-induced oxidative stress. Toxicol Appl Pharmacol 2012; 263:195-202.
16. Guth AM, Janssen WJ, Bosio C.M., Crouch EC, Henson PM, Dow SW. Lung environment determines unique phenotype of alveolar macrophages. Am J Physiol Lung Cell Mol Physiol 2009; 296: L936-L946.
17. Becker S, Madden MC, Newman S.L., Devlin RB, Koren HS. Modulation of human alveolar macrophage properties by ozone exposure in vitro. Toxicol Appl Pharmacol 1991; 110:403-415.
18. Ahmad S, Ahmad A, McConville G., Schneider BK, Allen CB, Manzer R, Mason R.J., White CW. Lung epithelial cells release ATP during ozone exposure: signaling for cell survival. Free Radic Biol Med 2005; 39: 213-226.
19. Devlin RB, McKinnon KP, Noah T, Becker S., Koren HS. Ozone-induced release of cytokines and fibronectin by alveolar macrophages and airway epithelial cells. Am J Physiol 1994; 266:L612-L619.
20. Kesic MJ, Meyer M, Bauer R., Jaspers I. Exposure to ozone modulates human airway protease/antiprotease balance contributing to increased influenza A infection. PLoS One 2012; 7: e35108.
21. Devlin RB, McDonnell WF, Becker S, Madden M.C., McGee MP, Perez R, Hatch G, House D.E., Koren HS. Time-dependent changes of inflammatory mediators in the lungs of humans exposed to 0.4 ppm ozone for 2 hr: a comparison of mediators found in bronchoalveolar lavage fluid 1 and 18 hr after exposure. Toxicol Appl Pharmacol 1996; 138:176-185.
22. Stone KC, Mercer RR, Gehr P, Stockstill B., Crapo JD. Allometric relationships of cell numbers and size in the mammalian lung. Am J Respir Cell Mol Biol 1992; 6:235-243.
23. Power CK, Burke CM, Sreenan S, Hurson B., Poulter LW. T-cell and macrophage subsets in the bronchial wall of clinically healthy subjects. Eur Respir J 1994; 7:437-441.
24. Hatch GE, Duncan KE, Diaz-Sanchez D, Schmitt M.T., Ghio AJ, Carraway MS, McKee J, Dailey L.A., Berntsen J., Devlin RB. Progress in assessing air pollutant risks from in vitro exposures: matching ozone dose and effect in human airway cells. Toxicol Sci (In press)
25. Muller L, Brighton LE, Jaspers I. Ozone exposed epithelial cells modify co-cultured natural killer cells. Am J Physiol Lung Cell Mol Physiol 2013; 304:L332-L341.
26. Kim CS, Alexis NE, Rappold A.G., Kehrl H., Hazucha MJ, Lay JC, Schmitt MT, Case M, Devlin R.B., Peden DB, et al. Lung function and inflammatory responses in healthy young adults exposed to 0.06 ppm ozone for 6.6 hours. Am J Respir Crit Care Med 2011; 183: 1215-1221.
27. Lay JC, Peden DB, Alexis NE. Flow cytometry of sputum: assessing inflammation and immune response elements in the bronchial airways. Inhal Toxicol 2011; 23:392-406.
28. Harbeck RJ. Immunophenotyping of bronchoalveolar lavage lymphocytes. Clin Diagn Lab Immunol 1998; 5:271-277.
29. Hernandez ML, Harris B, Lay J.C., Bromberg PA, Diaz-Sanchez D, Devlin RB, Kleeberger S.R., Alexis NE, Peden DB. Comparative airway inflammatory response of normal volunteers to ozone and lipopolysaccharide challenge. Inhal Toxicol 2010; 22:648-656.
30. Ambarus CA, Krausz S, van Eijk M, Hamann J, Radstake T.R., Reedquist KA, Tak PP, Baeten DL. Systematic validation of specific phenotypic markers for in vitro polarized human macrophages. J Immunol Methods 2012; 375:196-206.
31. Canton J, Neculai D, Grinstein S. Scavenger receptors in homeostasis and immunity. Nat Rev Immunol 2013; 13:621-634.
32. Mikerov AN, Umstead TM, Gan X, Huang W., Guo X, Wang G, Phelps D.S., Floros J. Impact of ozone exposure on the phagocytic activity of human surfactant protein A (SP-A) and SP-A variants. Am J Physiol Lung Cell Mol Physiol 2008; 294:L121-L130.
33. Karavitis J, Kovacs EJ. Macrophage phagocytosis: effects of environmental pollutants, alcohol, cigarette smoke, and other external factors. J Leukoc Biol 2011; 90:1065-1078.
34. Garantziotis S, Li Z, Potts E.N., Lindsey JY, Stober VP, Polosukhin VV, Blackwell T.S., Schwartz DA, Foster WM, Hollingsworth JW. TLR4 is necessary for hyaluronan-mediated airway hyperresponsiveness after ozone inhalation. Am J Respir Crit Care Med 2010; 181: 666-675.
35. Culty M, Nguyen HA, Underhill CB. The hyaluronan receptor (CD44) participates in the uptake and degradation of hyaluronan. J Cell Biol 1992; 116:1055-1062.
36. Devlin RB, McDonnell WF, Mann R, Becker S., House DE, Schreinemachers D, Koren HS. Exposure of humans to ambient levels of ozone for 6.6 hours causes cellular and biochemical changes in the lung. Am J Respir Cell Mol Biol 1991; 4:72-81.
37. Hussell T, Bell TJ. Alveolar macrophages: plasticity in a tissue-specific context. Nat Rev Immunol 2014; 14:81-93.
38. Bedoret D, Wallemacq H, Marichal T., Desmet C, Quesada Calvo F, Henry E, et al. Lung interstitial macrophages alter dendritic cell functions to prevent airway allergy in mice. J Clin Invest 2009; 119: 3723-3738.
39. Westphalen K, Gusarova GA, Islam M.N., Subramanian M., Cohen TS, Prince AS, Bhattacharya J. Sessile alveolar macrophages communicate with alveolar epithelium to modulate immunity. Nature 2014; 506: 503-506.
40. Holt PG. Down-regulation of immune responses in the lower respiratory tract: the role of alveolar macrophages. Clin Exp Immunol 1986; 63:261-270.
41. Alexis NE, Lay JC, Hazucha M, Harris B., Hernandez ML, Bromberg PA, Kehrl H, Diaz-Sanchez D, Kim C., Devlin RB, et al. Low-level ozone exposure induces airways inflammation and modifies cell surface phenotypes in healthy humans. Inhal Toxicol 2010; 22:593-600.
42. Mikerov AN, Gan X, Umstead T.M., Miller L., Chinchilli VM, Phelps DS, Floros J. Sex differences in the impact of ozone on survival and alveolar macrophage function of mice after Klebsiella pneumoniae infection. Respir Res 2008; 9:24.
43. 3 exposure: differences in disease susceptibility and neutrophil recruitment. Toxicol Appl Pharmacol 1993; 123: 211-218.
44. Li Z, Potts-Kant EN, Garantziotis S., Foster WM, Hollingsworth JW. Hyaluronan signaling during ozone-induced lung injury requires TLR4, MyD88, and TIRAP. PLoS One 2011; 6:e27137.
45. Jörres RA, Holz O, Zachgo W., Timm P, Koschyk S, Müller B, Grimminger F., Seeger W, Kelly FJ, Dunster C, et al. The effect of repeated ozone exposures on inflammatory markers in bronchoalveolar lavage fluid and mucosal biopsies. Am J Respir Crit Care Med 2000; 161:1855-1861.
46. Fujii T, Hayashi S, Hogg J.C., Mukae H., Suwa T, Goto Y, Vincent R., van Eeden SF. Interaction of alveolar macrophages and airway epithelial cells following exposure to particulate matter produces mediators that stimulate the bone marrow. Am J Respir Cell Mol Biol 2002; 27:34-41.
47. Tao F, Kobzik L. Lung macrophage-epithelial cell interactions amplify particle-mediated cytokine release. Am J Respir Cell Mol Biol 2002; 26:499-505.
48. Manzer R, Dinarello CA, McConville G, Mason RJ. Ozone exposure of macrophages induces an alveolar epithelial chemokine response through IL-1a. Am J Respir Cell Mol Biol 2008; 38: 318-323.