메뉴 건너뛰기




Volumn 113, Issue 3, 2015, Pages 452-463

Peroxisomes in cardiomyocytes and the peroxisome/peroxisome proliferator-activated receptor-loop

Author keywords

Heart failure; Peroxisomal disorders; Peroxisome; Peroxisome proliferatoractivated receptor; oxidation of fatty acids

Indexed keywords

ADENOSINE TRIPHOSPHATASE; CATALASE; MEMBRANE PROTEIN; MESSENGER RNA; PEROXISOMAL MEMBRANE PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PHYTANIC ACID; PYRUVATE DEHYDROGENASE KINASE 4; STEROL CARRIER PROTEIN 2; UNCLASSIFIED DRUG; FATTY ACID;

EID: 84924140987     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH14-06-0497     Document Type: Article
Times cited : (42)

References (100)
  • 1
    • 78650710691 scopus 로고    scopus 로고
    • Molecular pathways underlying cardiac remodeling during pathophysiological stimulation
    • Kehat I, Molkentin JD. Molecular pathways underlying cardiac remodeling during pathophysiological stimulation. Circulation 2010; 122: 2727–2735.
    • (2010) Circulation , vol.122 , pp. 2727-2735
    • Kehat, I.1    Molkentin, J.D.2
  • 2
    • 42049109696 scopus 로고    scopus 로고
    • Cardiac remodeling in obesity
    • Abel ED, et al. Cardiac remodeling in obesity. Physiol Rev 2008; 88: 389–419.
    • (2008) Physiol Rev , vol.88 , pp. 389-419
    • Abel, E.D.1
  • 3
    • 74949133862 scopus 로고    scopus 로고
    • Myocardial fatty acid metabolism in health and disease
    • Lopaschuk GD, et al. Myocardial fatty acid metabolism in health and disease. Physiol Rev 2010; 90: 207–258.
    • (2010) Physiol Rev , vol.90 , pp. 207-258
    • Lopaschuk, G.D.1
  • 4
    • 78650318083 scopus 로고    scopus 로고
    • In obese Zucker rats, lipids accumulate in the heart despite normal mitochondrial content, morphology and long-chain fatty acid oxidation
    • Holloway GP, et al. In obese Zucker rats, lipids accumulate in the heart despite normal mitochondrial content, morphology and long-chain fatty acid oxidation. J Physiol 2011; 589: 169–180.
    • (2011) J Physiol , vol.589 , pp. 169-180
    • Holloway, G.P.1
  • 5
    • 84856018357 scopus 로고    scopus 로고
    • Fatty heart, cardiac damage, and inflammation
    • Guzzardi MA, Iozzo P. Fatty heart, cardiac damage, and inflammation. Rev Diabet Stud 2011; 8: 403–417.
    • (2011) Rev Diabet Stud , vol.8 , pp. 403-417
    • Guzzardi, M.A.1    Iozzo, P.2
  • 6
    • 34347352169 scopus 로고    scopus 로고
    • Diabetic cardiomyopathy revisited
    • Boudina S, Abel ED. Diabetic cardiomyopathy revisited. Circulation 2007; 115: 3213–3223.
    • (2007) Circulation , vol.115 , pp. 3213-3223
    • Boudina, S.1    Abel, E.D.2
  • 7
    • 33644766038 scopus 로고    scopus 로고
    • Protection of cardiac mitochondria by overexpression of MnSOD reduces diabetic cardiomyopathy
    • Shen X, Zheng S, Metreveli NS, et al. Protection of cardiac mitochondria by overexpression of MnSOD reduces diabetic cardiomyopathy. Diabetes 2006; 55: 798–805.
    • (2006) Diabetes , vol.55 , pp. 798-805
    • Shen, X.1    Zheng, S.2    Metreveli, N.S.3
  • 8
    • 2342563763 scopus 로고    scopus 로고
    • Catalase protects cardiomyocyte function in models of type 1 and type 2 diabetes
    • Ye G, et al. Catalase protects cardiomyocyte function in models of type 1 and type 2 diabetes. Diabetes 2004; 53: 1336–1343.
    • (2004) Diabetes , vol.53 , pp. 1336-1343
    • Ye, G.1
  • 10
    • 0038737699 scopus 로고
    • Modification physiologiques et pathologiques du chondriome
    • Gänsler H, Rouiller C. Modification physiologiques et pathologiques du chondriome. Schweiz Z Allg Pathol Bakt 1956; 19: 217–243.
    • (1956) Schweiz Z Allg Pathol Bakt , vol.19 , pp. 217-243
    • Gänsler, H.1    Rouiller, C.2
  • 11
    • 0030815550 scopus 로고    scopus 로고
    • Application of in situ hybridisation, cytochemical and immunocytochemical techniques for the investigation of peroxisomes
    • A review including novel data. Robert Feulgen Prize Lecture 1997
    • Baumgart E. Application of in situ hybridisation, cytochemical and immunocytochemical techniques for the investigation of peroxisomes. A review including novel data. Robert Feulgen Prize Lecture 1997. Histochem Cell Biol 1997; 108: 185–210.
    • (1997) Histochem Cell Biol , vol.108 , pp. 185-210
    • Baumgart, E.1
  • 12
    • 0013897667 scopus 로고
    • Peroxisomes (Microbodies and related particles)
    • De Duve C, Baudhuin P. Peroxisomes (microbodies and related particles). Physiol Rev 1966; 46: 323–357.
    • (1966) Physiol Rev , vol.46 , pp. 323-357
    • De Duve, C.1    Baudhuin, P.2
  • 13
    • 0013788558 scopus 로고
    • Combined biochemical and morphological study of particulate fractions from rat liver. Analysis of preparations enriched in lysosomes or in particles containing urate oxidase, D-amino acid oxidase, and catalase
    • Baudhuin P, et al. Combined biochemical and morphological study of particulate fractions from rat liver. Analysis of preparations enriched in lysosomes or in particles containing urate oxidase, D-amino acid oxidase, and catalase. J Cell Biol 1965; 26: 219–243.
    • (1965) J Cell Biol , vol.26 , pp. 219-243
    • Baudhuin, P.1
  • 14
    • 33746366462 scopus 로고    scopus 로고
    • Biochemistry of mammalian peroxisomes revisited
    • Wanders RJ, Waterham HR. Biochemistry of mammalian peroxisomes revisited. Annu Rev Biochem 2006; 75: 295–332.
    • (2006) Annu Rev Biochem , vol.75 , pp. 295-332
    • Wanders, R.J.1    Waterham, H.R.2
  • 15
    • 33846991643 scopus 로고    scopus 로고
    • Localisation of the pre-squalene segment of the isoprenoid biosynthetic pathway in mammalian peroxisomes
    • Kovacs WJ, et al. Localisation of the pre-squalene segment of the isoprenoid biosynthetic pathway in mammalian peroxisomes. Histochem Cell Biol 2007; 127: 273–290.
    • (2007) Histochem Cell Biol , vol.127 , pp. 273-290
    • Kovacs, W.J.1
  • 16
    • 10144261887 scopus 로고    scopus 로고
    • A unified nomenclature for peroxisome biogenesis factors
    • Distel B, et al. A unified nomenclature for peroxisome biogenesis factors. J Cell Biol 1996; 135: 1–3.
    • (1996) J Cell Biol , vol.135 , pp. 1-3
    • Distel, B.1
  • 17
    • 84906491186 scopus 로고    scopus 로고
    • Peroxisome biogenesis in mammalian cells
    • Fujiki Y, et al. Peroxisome biogenesis in mammalian cells. Front Physiol 2014; 5: 307.
    • (2014) Front Physiol , vol.5 , pp. 307
    • Fujiki, Y.1
  • 18
    • 0015848845 scopus 로고
    • Peroxisomal and mitochondrial defects in the cerebro-hepato-renal syndrome
    • Goldfischer S, Moore CL, Johnson AB, et al. Peroxisomal and mitochondrial defects in the cerebro-hepato-renal syndrome. Science 1973; 182: 62–64.
    • (1973) Science , vol.182 , pp. 62-64
    • Goldfischer, S.1    Moore, C.L.2    Johnson, A.B.3
  • 19
    • 14244267510 scopus 로고    scopus 로고
    • Peroxisomal disorders I: Biochemistry and genetics of peroxisome biogenesis disorders
    • Wanders RJ, Waterham HR. Peroxisomal disorders I: biochemistry and genetics of peroxisome biogenesis disorders. Clin Genet 2005; 67: 107–133.
    • (2005) Clin Genet , vol.67 , pp. 107-133
    • Wanders, R.J.1    Waterham, H.R.2
  • 20
    • 0023198567 scopus 로고
    • Peroxisomal disorders: Clinical characterisation
    • Monnens L, Heymans H. Peroxisomal disorders: clinical characterisation. J Inherit Metab Dis 1987; 10 (Suppl 1): 23–32.
    • (1987) J Inherit Metab Dis , vol.10 , pp. 23-32
    • Monnens, L.1    Heymans, H.2
  • 21
    • 77956867734 scopus 로고    scopus 로고
    • Biochemistry and genetics of inherited disorders of peroxisomal fatty acid metabolism
    • Van Veldhoven PP. Biochemistry and genetics of inherited disorders of peroxisomal fatty acid metabolism. J Lipid Res 2010; 51: 2863–2895.
    • (2010) J Lipid Res , vol.51 , pp. 2863-2895
    • Van Veldhoven, P.P.1
  • 22
    • 33845304296 scopus 로고    scopus 로고
    • Peroxisomal disorders: The single peroxisomal enzyme deficiencies
    • Wanders RJ, Waterham HR. Peroxisomal disorders: the single peroxisomal enzyme deficiencies. Biochim Biophys Acta 2006; 1763: 1707–1720.
    • (2006) Biochim Biophys Acta , vol.1763 , pp. 1707-1720
    • Wanders, R.J.1    Waterham, H.R.2
  • 23
    • 61649120588 scopus 로고    scopus 로고
    • Identification of novel mutations and sequence variation in the Zellweger syndrome spectrum of peroxisome biogenesis disorders
    • Yik WY, et al. Identification of novel mutations and sequence variation in the Zellweger syndrome spectrum of peroxisome biogenesis disorders. Hum Mutat 2009; 30: E467-E480.
    • (2009) Hum Mutat , vol.30 , pp. E467-E480
    • Yik, W.Y.1
  • 24
    • 0034809616 scopus 로고    scopus 로고
    • Cardiac Characteristics of Transgenic Mice Overexpressing Refsum Disease Gene-Associated Protein within the Heart
    • Koh JT, et al. Cardiac Characteristics of Transgenic Mice Overexpressing Refsum Disease Gene-Associated Protein within the Heart. Biochem Biophys Res Commun 2001; 286: 1107–1116.
    • (2001) Biochem Biophys Res Commun , vol.286 , pp. 1107-1116
    • Koh, J.T.1
  • 25
    • 36749094170 scopus 로고    scopus 로고
    • Peroxisomes, Refsum’s disease and the alpha- and omega-oxidation of phytanic acid
    • Wanders RJ, Komen JC. Peroxisomes, Refsum’s disease and the alpha- and omega-oxidation of phytanic acid. Biochem Soc Trans 2007; 35: 865–869.
    • (2007) Biochem Soc Trans , vol.35 , pp. 865-869
    • Wanders, R.J.1    Komen, J.C.2
  • 26
    • 84862011841 scopus 로고    scopus 로고
    • Phytanic acid disturbs mitochondrial homeostasis in heart of young rats: A possible pathomechanism of cardiomyopathy in Refsum disease
    • Grings M, et al. Phytanic acid disturbs mitochondrial homeostasis in heart of young rats: a possible pathomechanism of cardiomyopathy in Refsum disease. Mol Cell Biochem 2012; 366: 335–343.
    • (2012) Mol Cell Biochem , vol.366 , pp. 335-343
    • Grings, M.1
  • 27
    • 16944361876 scopus 로고    scopus 로고
    • A mouse model for Zellweger syndrome
    • Baes M, et al. A mouse model for Zellweger syndrome. Nat Genet 1997; 17: 49–57.
    • (1997) Nat Genet , vol.17 , pp. 49-57
    • Baes, M.1
  • 28
    • 0030830906 scopus 로고    scopus 로고
    • Targeted deletion of the PEX2 peroxisome assembly gene in mice provides a model for Zellweger syndrome, a human neuronal migration disorder
    • Faust PL, Hatten ME. Targeted deletion of the PEX2 peroxisome assembly gene in mice provides a model for Zellweger syndrome, a human neuronal migration disorder. J Cell Biol 1997; 139: 1293–1305.
    • (1997) J Cell Biol , vol.139 , pp. 1293-1305
    • Faust, P.L.1    Hatten, M.E.2
  • 29
    • 0036882106 scopus 로고    scopus 로고
    • PEX11alpha is required for peroxisome proliferation in response to 4-phenylbutyrate but is dispensable for peroxisome proliferator-activated receptor alpha-mediated peroxisome proliferation
    • Li X, et al. PEX11alpha is required for peroxisome proliferation in response to 4-phenylbutyrate but is dispensable for peroxisome proliferator-activated receptor alpha-mediated peroxisome proliferation. Mol Cell Biol 2002; 22: 8226–8240.
    • (2002) Mol Cell Biol , vol.22 , pp. 8226-8240
    • Li, X.1
  • 30
    • 0036261777 scopus 로고    scopus 로고
    • PEX11 beta deficiency is lethal and impairs neuronal migration but does not abrogate peroxisome function
    • Li X, et al. PEX11 beta deficiency is lethal and impairs neuronal migration but does not abrogate peroxisome function. Mol Cell Biol 2002; 22: 4358–4365.
    • (2002) Mol Cell Biol , vol.22 , pp. 4358-4365
    • Li, X.1
  • 31
    • 0042632799 scopus 로고    scopus 로고
    • Pex13 inactivation in the mouse disrupts peroxisome biogenesis and leads to a Zellweger syndrome phenotype
    • Maxwell M, et al. Pex13 inactivation in the mouse disrupts peroxisome biogenesis and leads to a Zellweger syndrome phenotype. Mol Cell Biol 2003; 23: 5947–5957.
    • (2003) Mol Cell Biol , vol.23 , pp. 5947-5957
    • Maxwell, M.1
  • 32
    • 10744225661 scopus 로고    scopus 로고
    • Impaired neuronal migration and endochondral ossification in Pex7 knockout mice: A model for rhizomelic chondrodysplasia punctata
    • Brites P, et al. Impaired neuronal migration and endochondral ossification in Pex7 knockout mice: a model for rhizomelic chondrodysplasia punctata. Hum Mol Genet 2003; 12: 2255–2267.
    • (2003) Hum Mol Genet , vol.12 , pp. 2255-2267
    • Brites, P.1
  • 33
    • 10144234128 scopus 로고    scopus 로고
    • Hepatocellular and hepatic peroxisomal alterations in mice with a disrupted peroxisomal fatty acyl-coenzyme A oxidase gene
    • Fan CY, et al. Hepatocellular and hepatic peroxisomal alterations in mice with a disrupted peroxisomal fatty acyl-coenzyme A oxidase gene. J Biol Chem 1996; 271: 24698–24710.
    • (1996) J Biol Chem , vol.271 , pp. 24698-24710
    • Fan, C.Y.1
  • 34
    • 0034717058 scopus 로고    scopus 로고
    • Inactivation of the peroxisomal multifunctional protein-2 in mice impedes the degradation of not only 2-methyl-branched fatty acids and bile acid intermediates but also of very long chain fatty acids
    • Baes M, et al. Inactivation of the peroxisomal multifunctional protein-2 in mice impedes the degradation of not only 2-methyl-branched fatty acids and bile acid intermediates but also of very long chain fatty acids. J Biol Chem 2000; 275: 16329–16336.
    • (2000) J Biol Chem , vol.275 , pp. 16329-16336
    • Baes, M.1
  • 35
    • 0042131525 scopus 로고    scopus 로고
    • Inactivation of ether lipid biosynthesis causes male infertility, defects in eye development and optic nerve hypoplasia in mice
    • Rodemer C, et al. Inactivation of ether lipid biosynthesis causes male infertility, defects in eye development and optic nerve hypoplasia in mice. Hum Mol Genet 2003; 12: 1881–1895.
    • (2003) Hum Mol Genet , vol.12 , pp. 1881-1895
    • Rodemer, C.1
  • 36
    • 0034799180 scopus 로고    scopus 로고
    • Mitochondrial alterations caused by defective peroxisomal biogenesis in a mouse model for Zellweger syndrome (PEX5 knockout mouse)
    • Baumgart E, et al. Mitochondrial alterations caused by defective peroxisomal biogenesis in a mouse model for Zellweger syndrome (PEX5 knockout mouse). Am J Pathol 2001; 159: 1477–1494.
    • (2001) Am J Pathol , vol.159 , pp. 1477-1494
    • Baumgart, E.1
  • 37
    • 0020582364 scopus 로고
    • Biochemical studies in the liver and muscle of patients with Zellweger syndrome
    • Trijbels JM, et al. Biochemical studies in the liver and muscle of patients with Zellweger syndrome. Pediatr Res 1983; 17: 514–517.
    • (1983) Pediatr Res , vol.17 , pp. 514-517
    • Trijbels, J.M.1
  • 38
    • 10044248689 scopus 로고    scopus 로고
    • Phytanic acid accumulation is associated with conduction delay and sudden cardiac death in sterol carrier protein-2/sterol carrier protein- x deficient mice
    • Monnig G, et al. Phytanic acid accumulation is associated with conduction delay and sudden cardiac death in sterol carrier protein-2/sterol carrier protein- x deficient mice. J Cardiovasc Electrophysiol 2004; 15: 1310–1316.
    • (2004) J Cardiovasc Electrophysiol , vol.15 , pp. 1310-1316
    • Monnig, G.1
  • 39
    • 14444273907 scopus 로고    scopus 로고
    • Defective peroxisomal catabolism of branched fatty acyl coenzyme A in mice lacking the sterol carrier protein-2/sterol carrier protein-x gene function
    • Seedorf U, et al. Defective peroxisomal catabolism of branched fatty acyl coenzyme A in mice lacking the sterol carrier protein-2/sterol carrier protein-x gene function. Genes Dev 1998; 12: 1189–1201.
    • (1998) Genes Dev , vol.12 , pp. 1189-1201
    • Seedorf, U.1
  • 40
    • 84864039497 scopus 로고    scopus 로고
    • The importance of ether-phospholipids: A view from the perspective of mouse models
    • da Silva TF, et al. The importance of ether-phospholipids: a view from the perspective of mouse models. Biochim Biophys Acta 2012; 1822: 1501–1508.
    • (2012) Biochim Biophys Acta , vol.1822 , pp. 1501-1508
    • Da Silva, T.F.1
  • 41
    • 77649341208 scopus 로고    scopus 로고
    • A Pex7 hypomorphic mouse model for plasmalogen deficiency affecting the lens and skeleton
    • Braverman N, et al. A Pex7 hypomorphic mouse model for plasmalogen deficiency affecting the lens and skeleton. Mol Genet Metab 2010; 99: 408–416.
    • (2010) Mol Genet Metab , vol.99 , pp. 408-416
    • Braverman, N.1
  • 42
    • 0030946632 scopus 로고    scopus 로고
    • Human PEX7 encodes the peroxisomal PTS2 receptor and is responsible for rhizomelic chondrodysplasia punctata
    • Braverman N, et al. Human PEX7 encodes the peroxisomal PTS2 receptor and is responsible for rhizomelic chondrodysplasia punctata. Nat Genet 1997; 15: 369–376.
    • (1997) Nat Genet , vol.15 , pp. 369-376
    • Braverman, N.1
  • 43
    • 56649124783 scopus 로고    scopus 로고
    • Ataxia with loss of Purkinje cells in a mouse model for Refsum disease
    • Ferdinandusse S, et al. Ataxia with loss of Purkinje cells in a mouse model for Refsum disease. Proc Natl Acad Sci USA 2008; 105: 17712–17717.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 17712-17717
    • Ferdinandusse, S.1
  • 44
    • 0001642864 scopus 로고    scopus 로고
    • Current cytochemical techniques for the investigation of peroxisomes. A review
    • Fahimi HD, Baumgart E. Current cytochemical techniques for the investigation of peroxisomes. A review. J Histochem Cytochem 1999; 47: 1219–1232.
    • (1999) J Histochem Cytochem , vol.47 , pp. 1219-1232
    • Fahimi, H.D.1    Baumgart, E.2
  • 45
    • 0016043978 scopus 로고
    • Letter: Peroxisomes (microbodies) in striated muscle cells
    • Hand AR. Letter: Peroxisomes (microbodies) in striated muscle cells. J Histochem Cytochem 1974; 22: 207–209.
    • (1974) J Histochem Cytochem , vol.22 , pp. 207-209
    • Hand, A.R.1
  • 46
    • 0016229231 scopus 로고
    • Microbodies (Peroxisomes) containing catalase in myocardium: Morphological and biochemical evidence
    • Herzog V, Fahimi HD. Microbodies (peroxisomes) containing catalase in myocardium: morphological and biochemical evidence. Science 1974; 185: 271–273.
    • (1974) Science , vol.185 , pp. 271-273
    • Herzog, V.1    Fahimi, H.D.2
  • 47
    • 0017352772 scopus 로고
    • Peroxisomes (Microbodies) in the myocardium of rodents and primates
    • A comparative Ultrastructural cytochemical study
    • Hicks L, Fahimi HD. Peroxisomes (microbodies) in the myocardium of rodents and primates. A comparative Ultrastructural cytochemical study. Cell Tissue Res 1977; 175: 467–481.
    • (1977) Cell Tissue Res , vol.175 , pp. 467-481
    • Hicks, L.1    Fahimi, H.D.2
  • 48
    • 0028173462 scopus 로고
    • The peroxisomal beta-oxidation enzyme system of rat heart. Basal level and effect of the peroxisome proliferator clofibrate
    • Kvannes J, et al. The peroxisomal beta-oxidation enzyme system of rat heart. Basal level and effect of the peroxisome proliferator clofibrate. Biochim Biophys Acta 1994; 1201: 203–216.
    • (1994) Biochim Biophys Acta , vol.1201 , pp. 203-216
    • Kvannes, J.1
  • 49
    • 0028289751 scopus 로고
    • Peroxisomes in liver, heart, and kidney of mice fed a commercial fish oil preparation: Original data and review on peroxisomal changes induced by high-fat diets
    • De Craemer D, et al. Peroxisomes in liver, heart, and kidney of mice fed a commercial fish oil preparation: original data and review on peroxisomal changes induced by high-fat diets. J Lipid Res 1994; 35: 1241–1250.
    • (1994) J Lipid Res , vol.35 , pp. 1241-1250
    • De Craemer, D.1
  • 50
    • 0018601305 scopus 로고
    • The effect of feeding rats with partially hydrogenated marine oil or rapeseed oil on the chain shortening of erucic acid in perfused heart
    • Norseth J. The effect of feeding rats with partially hydrogenated marine oil or rapeseed oil on the chain shortening of erucic acid in perfused heart. Biochim Biophys Acta 1979; 575: 1–9.
    • (1979) Biochim Biophys Acta , vol.575 , pp. 1-9
    • Norseth, J.1
  • 51
    • 0028923505 scopus 로고
    • On the mechanism of stimulation of peroxisomal beta-oxidation in rat heart by partially hydrogenated fish oil
    • Kvannes J, et al. On the mechanism of stimulation of peroxisomal beta-oxidation in rat heart by partially hydrogenated fish oil. Biochim Biophys Acta 1995; 1255: 39–49.
    • (1995) Biochim Biophys Acta , vol.1255 , pp. 39-49
    • Kvannes, J.1
  • 52
    • 0018407452 scopus 로고
    • Increased myocardial catalase in rats fed ethanol
    • Fahimi HD, et al. Increased myocardial catalase in rats fed ethanol. Am J Pathol 1979; 96: 373–390.
    • (1979) Am J Pathol , vol.96 , pp. 373-390
    • Fahimi, H.D.1
  • 53
    • 0019378113 scopus 로고
    • Chronic effects of ethanol under partial inhibition of catalase activity in the rat heart: Light and electron microscopic observations
    • Kino M. Chronic effects of ethanol under partial inhibition of catalase activity in the rat heart: light and electron microscopic observations. J Mol Cell Cardiol 1981; 13: 5–21.
    • (1981) J Mol Cell Cardiol , vol.13 , pp. 5-21
    • Kino, M.1
  • 54
    • 84881228813 scopus 로고    scopus 로고
    • Mammalian SOD2 is exclusively located in mitochondria and not present in peroxisomes
    • Karnati S, et al. Mammalian SOD2 is exclusively located in mitochondria and not present in peroxisomes. Histochem Cell Biol 2013; 140: 105–117.
    • (2013) Histochem Cell Biol , vol.140 , pp. 105-117
    • Karnati, S.1
  • 55
    • 84878015345 scopus 로고    scopus 로고
    • Activated peroxisomal fatty acid metabolism improves cardiac recovery in ischemia-reperfusion
    • Liepinsh E, et al. Activated peroxisomal fatty acid metabolism improves cardiac recovery in ischemia-reperfusion. Naunyn Schmiedebergs Arch Pharmacol 2013; 386: 541–550.
    • (2013) Naunyn Schmiedebergs Arch Pharmacol , vol.386 , pp. 541-550
    • Liepinsh, E.1
  • 56
    • 0346750819 scopus 로고    scopus 로고
    • Transcriptional profiling of the heart reveals chamber-specific gene expression patterns
    • Tabibiazar R, et al. Transcriptional profiling of the heart reveals chamber-specific gene expression patterns. Circ Res 2003; 93: 1193–1201.
    • (2003) Circ Res , vol.93 , pp. 1193-1201
    • Tabibiazar, R.1
  • 57
    • 0025365409 scopus 로고
    • Immunohistochemical localisation of antioxidant enzymes in adult Syrian hamster tissues and during kidney development
    • Oberley TD, et al. Immunohistochemical localisation of antioxidant enzymes in adult Syrian hamster tissues and during kidney development. Am J Pathol 1990; 137: 199–214.
    • (1990) Am J Pathol , vol.137 , pp. 199-214
    • Oberley, T.D.1
  • 58
    • 84885421198 scopus 로고    scopus 로고
    • The biogenesis protein PEX14 is an optimal marker for the identification and localisation of peroxisomes in different cell types, tissues, and species in morphological studies
    • Grant P, et al. The biogenesis protein PEX14 is an optimal marker for the identification and localisation of peroxisomes in different cell types, tissues, and species in morphological studies. Histochem Cell Biol 2013; 140: 423–442.
    • (2013) Histochem Cell Biol , vol.140 , pp. 423-442
    • Grant, P.1
  • 59
    • 83255187158 scopus 로고    scopus 로고
    • A subtle interplay between three Pex11 proteins shapes de novo formation and fission of peroxisomes
    • Huber A, et al. A subtle interplay between three Pex11 proteins shapes de novo formation and fission of peroxisomes. Traffic 2012; 13: 157–167.
    • (2012) Traffic , vol.13 , pp. 157-167
    • Huber, A.1
  • 60
    • 77955986557 scopus 로고    scopus 로고
    • PEX11 family members are membrane elongation factors that coordinate peroxisome proliferation and maintenance
    • Koch J, et al. PEX11 family members are membrane elongation factors that coordinate peroxisome proliferation and maintenance. J Cell Sci 2010; 123: 3389–3400.
    • (2010) J Cell Sci , vol.123 , pp. 3389-3400
    • Koch, J.1
  • 61
    • 0026517010 scopus 로고
    • Control of the peroxisomal beta-oxidation pathway by a novel family of nuclear hormone receptors
    • Dreyer C, et al. Control of the peroxisomal beta-oxidation pathway by a novel family of nuclear hormone receptors. Cell 1992; 68: 879–887.
    • (1992) Cell , vol.68 , pp. 879-887
    • Dreyer, C.1
  • 62
    • 0345735302 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor delta activates fatty acid oxidation in cultured neonatal and adult cardiomyocytes
    • Cheng L, et al. Peroxisome proliferator-activated receptor delta activates fatty acid oxidation in cultured neonatal and adult cardiomyocytes. Biochem Biophys Res Commun 2004; 313: 277–286.
    • (2004) Biochem Biophys Res Commun , vol.313 , pp. 277-286
    • Cheng, L.1
  • 63
    • 79551492273 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor beta/delta activation in adult hearts facilitates mitochondrial function and cardiac performance under pressure-overload condition
    • Liu J, et al. Peroxisome proliferator-activated receptor beta/delta activation in adult hearts facilitates mitochondrial function and cardiac performance under pressure-overload condition. Hypertension 2011; 57: 223–230.
    • (2011) Hypertension , vol.57 , pp. 223-230
    • Liu, J.1
  • 64
    • 68149125511 scopus 로고    scopus 로고
    • Effects of chronic PPAR-agonist treatment on cardiac structure and function, blood pressure, and kidney in healthy sprague-dawley rats
    • Blasi ER, et al. Effects of chronic PPAR-agonist treatment on cardiac structure and function, blood pressure, and kidney in healthy sprague-dawley rats. PPAR Res 2009; 2009: 237865.
    • (2009) PPAR Res , vol.2009
    • Blasi, E.R.1
  • 65
    • 56749130032 scopus 로고    scopus 로고
    • Structure of the intact PPAR-gamma-RXR- nuclear receptor complex on DNA
    • Chandra V, et al. Structure of the intact PPAR-gamma-RXR- nuclear receptor complex on DNA. Nature 2008; 456: 350–356.
    • (2008) Nature , vol.456 , pp. 350-356
    • Chandra, V.1
  • 66
    • 0030047806 scopus 로고    scopus 로고
    • Differential expression of peroxisome proliferator-activated receptors (PPARs): Tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat
    • Braissant O, et al. Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat. Endocrinology 1996; 137: 354–366.
    • (1996) Endocrinology , vol.137 , pp. 354-366
    • Braissant, O.1
  • 67
    • 0035147341 scopus 로고    scopus 로고
    • Detection of peroxisomal proteins and their mRNAs in serial sections of fetal and newborn mouse organs
    • Grabenbauer M, et al. Detection of peroxisomal proteins and their mRNAs in serial sections of fetal and newborn mouse organs. J Histochem Cytochem 2001; 49: 155–164.
    • (2001) J Histochem Cytochem , vol.49 , pp. 155-164
    • Grabenbauer, M.1
  • 68
    • 36849068108 scopus 로고    scopus 로고
    • Nuclear receptors PPARbeta/delta and PPARalpha direct distinct metabolic regulatory programs in the mouse heart
    • Burkart EM, et al. Nuclear receptors PPARbeta/delta and PPARalpha direct distinct metabolic regulatory programs in the mouse heart. J Clin Invest 2007; 117: 3930–3939.
    • (2007) J Clin Invest , vol.117 , pp. 3930-3939
    • Burkart, E.M.1
  • 69
    • 0025132245 scopus 로고
    • Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
    • Issemann I, Green S. Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators. Nature 1990; 347: 645–650.
    • (1990) Nature , vol.347 , pp. 645-650
    • Issemann, I.1    Green, S.2
  • 70
    • 0026541591 scopus 로고
    • The mouse peroxisome proliferator activated receptor recognizes a response element in the 5’ flanking sequence of the rat acyl CoA oxidase gene
    • Tugwood JD, et al. The mouse peroxisome proliferator activated receptor recognizes a response element in the 5’ flanking sequence of the rat acyl CoA oxidase gene. EMBO J 1992; 11: 433–439.
    • (1992) EMBO J , vol.11 , pp. 433-439
    • Tugwood, J.D.1
  • 71
    • 21244492310 scopus 로고    scopus 로고
    • Myocardial substrate metabolism in the normal and failing heart
    • Stanley WC, et al. Myocardial substrate metabolism in the normal and failing heart. Physiol Rev 2005; 85: 1093–1129.
    • (2005) Physiol Rev , vol.85 , pp. 1093-1129
    • Stanley, W.C.1
  • 72
    • 0035929170 scopus 로고    scopus 로고
    • Adaptive increase in pyruvate dehydrogenase kinase 4 during starvation is mediated by peroxisome proliferator-activated receptor alpha
    • Wu P, et al. Adaptive increase in pyruvate dehydrogenase kinase 4 during starvation is mediated by peroxisome proliferator-activated receptor alpha. Biochem Biophys Res Commun 2001; 287: 391–396.
    • (2001) Biochem Biophys Res Commun , vol.287 , pp. 391-396
    • Wu, P.1
  • 73
    • 0036066319 scopus 로고    scopus 로고
    • Regulation of pyruvate dehydrogenase kinase expression by peroxisome proliferator-activated receptor-alpha ligands, glucocorticoids, and insulin
    • Huang B, et al. Regulation of pyruvate dehydrogenase kinase expression by peroxisome proliferator-activated receptor-alpha ligands, glucocorticoids, and insulin. Diabetes 2002; 51: 276–283.
    • (2002) Diabetes , vol.51 , pp. 276-283
    • Huang, B.1
  • 74
    • 0017306759 scopus 로고
    • Regulation of pyruvate dehydrogenase in rat heart. Mechanism of regulation of proportions of dephosphorylated and phosphorylated enzyme by oxidation of fatty acids and ketone bodies and of effects of diabetes: Role of coenzyme A, acetyl-coenzyme A and reduced and oxidized nicotinamide-adenine dinucleotide
    • Kerbey AL, et al. Regulation of pyruvate dehydrogenase in rat heart. Mechanism of regulation of proportions of dephosphorylated and phosphorylated enzyme by oxidation of fatty acids and ketone bodies and of effects of diabetes: role of coenzyme A, acetyl-coenzyme A and reduced and oxidized nicotinamide-adenine dinucleotide. Biochem J 1976; 154: 327–348.
    • (1976) Biochem J , vol.154 , pp. 327-348
    • Kerbey, A.L.1
  • 75
    • 0015048432 scopus 로고
    • Active and inactive forms of pyruvate dehydrogenase in rat heart and kidney: Effect of diabetes, fasting, and refeeding on pyruvate dehydrogenase interconversion
    • Wieland O, et al. Active and inactive forms of pyruvate dehydrogenase in rat heart and kidney: effect of diabetes, fasting, and refeeding on pyruvate dehydrogenase interconversion. Arch Biochem Biophys 1971; 143: 593–601.
    • (1971) Arch Biochem Biophys , vol.143 , pp. 593-601
    • Wieland, O.1
  • 76
    • 0034698051 scopus 로고    scopus 로고
    • Constitutive regulation of cardiac fatty acid metabolism through peroxisome proliferator-activated receptor alpha associated with agedependent cardiac toxicity
    • Watanabe K, et al. Constitutive regulation of cardiac fatty acid metabolism through peroxisome proliferator-activated receptor alpha associated with agedependent cardiac toxicity. J Biol Chem 2000; 275: 22293–22299.
    • (2000) J Biol Chem , vol.275 , pp. 22293-22299
    • Watanabe, K.1
  • 77
    • 26844561663 scopus 로고    scopus 로고
    • Decreased contractile and metabolic reserve in peroxisome proliferator- activated receptor-alpha-null hearts can be rescued by increasing glucose transport and utilisation
    • Luptak I, et al. Decreased contractile and metabolic reserve in peroxisome proliferator- activated receptor-alpha-null hearts can be rescued by increasing glucose transport and utilisation. Circulation 2005; 112: 2339–2346.
    • (2005) Circulation , vol.112 , pp. 2339-2346
    • Luptak, I.1
  • 78
    • 0036143320 scopus 로고    scopus 로고
    • The cardiac phenotype induced by PPARalpha overexpression mimics that caused by diabetes mellitus
    • Finck BN, et al. The cardiac phenotype induced by PPARalpha overexpression mimics that caused by diabetes mellitus. J Clin Invest 2002; 109: 121–130.
    • (2002) J Clin Invest , vol.109 , pp. 121-130
    • Finck, B.N.1
  • 79
    • 33845577985 scopus 로고    scopus 로고
    • The PPAR regulatory system in cardiac physiology and disease
    • Finck BN. The PPAR regulatory system in cardiac physiology and disease. Cardiovasc Res 2007; 73: 269–277.
    • (2007) Cardiovasc Res , vol.73 , pp. 269-277
    • Finck, B.N.1
  • 80
    • 44649151707 scopus 로고    scopus 로고
    • The PPAR trio: Regulators of myocardial energy metabolism in health and disease
    • Madrazo JA, Kelly DP. The PPAR trio: regulators of myocardial energy metabolism in health and disease. J Mol Cell Cardiol 2008; 44: 968–975.
    • (2008) J Mol Cell Cardiol , vol.44 , pp. 968-975
    • Madrazo, J.A.1    Kelly, D.P.2
  • 81
    • 0042405041 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors (PPARS): Regulators of gene expression in heart and skeletal muscle
    • Gilde AJ, Van Bilsen M. Peroxisome proliferator-activated receptors (PPARS): regulators of gene expression in heart and skeletal muscle. Acta Physiol Scand 2003; 178: 425–434.
    • (2003) Acta Physiol Scand , vol.178 , pp. 425-434
    • Gilde, A.J.1    Van Bilsen, M.2
  • 82
    • 34948910262 scopus 로고    scopus 로고
    • Cardiomyocyte expression of PPARgamma leads to cardiac dysfunction in mice
    • Son NH, et al. Cardiomyocyte expression of PPARgamma leads to cardiac dysfunction in mice. J Clin Invest 2007; 117: 2791–2801.
    • (2007) J Clin Invest , vol.117 , pp. 2791-2801
    • Son, N.H.1
  • 83
    • 24044476859 scopus 로고    scopus 로고
    • Cardiomyocyte-specific knockout and agonist of peroxisome proliferator-activated receptor-gamma both induce cardiac hypertrophy in mice
    • Duan SZ, et al. Cardiomyocyte-specific knockout and agonist of peroxisome proliferator-activated receptor-gamma both induce cardiac hypertrophy in mice. Circ Res 2005; 97: 372–379.
    • (2005) Circ Res , vol.97 , pp. 372-379
    • Duan, S.Z.1
  • 84
    • 13944284526 scopus 로고    scopus 로고
    • PPAR-gamma activation fails to provide myocardial protection in ischemia and reperfusion in pigs
    • Xu Y, et al. PPAR-gamma activation fails to provide myocardial protection in ischemia and reperfusion in pigs. Am J Physiol Heart Circ Physiol 2005; 288: H1314–1323.
    • (2005) Am J Physiol Heart Circ Physiol , vol.288 , pp. H1314-H1323
    • Xu, Y.1
  • 85
    • 84857716778 scopus 로고    scopus 로고
    • Selective peroxisome proliferator-activated receptorgamma modulation to reduce cardiovascular risk in patients with insulin resistance
    • Yew T, Toh SA, Millar JS. Selective peroxisome proliferator-activated receptorgamma modulation to reduce cardiovascular risk in patients with insulin resistance. Recent Pat Cardiovasc Drug Discov 2012; 7: 33–41.
    • (2012) Recent Pat Cardiovasc Drug Discov , vol.7 , pp. 33-41
    • Yew, T.1    Toh, S.A.2    Millar, J.S.3
  • 86
    • 33646368165 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor subtypes differentially cooperate with other transcription factors in selective transactivation of the perilipin/PEX11 alpha gene pair
    • Shimizu M, et al. Peroxisome proliferator-activated receptor subtypes differentially cooperate with other transcription factors in selective transactivation of the perilipin/PEX11 alpha gene pair. J Biochem 2006; 139: 563–573.
    • (2006) J Biochem , vol.139 , pp. 563-573
    • Shimizu, M.1
  • 87
    • 84872396492 scopus 로고    scopus 로고
    • Pex11alpha deficiency impairs peroxisome elongation and division and contributes to nonalcoholic fatty liver in mice
    • Weng H, et al. Pex11alpha deficiency impairs peroxisome elongation and division and contributes to nonalcoholic fatty liver in mice. Am J Physiol Endocrinol Metab 2013; 304: E187-E196.
    • (2013) Am J Physiol Endocrinol Metab , vol.304 , pp. E187-E196
    • Weng, H.1
  • 88
    • 0032491315 scopus 로고    scopus 로고
    • Expression of PEX11beta mediates peroxisome proliferation in the absence of extracellular stimuli
    • Schrader M, et al. Expression of PEX11beta mediates peroxisome proliferation in the absence of extracellular stimuli. J Biol Chem 1998; 273: 29607–29614.
    • (1998) J Biol Chem , vol.273 , pp. 29607-29614
    • Schrader, M.1
  • 89
    • 84858301096 scopus 로고    scopus 로고
    • The human gene SLC25A17 encodes a peroxisomal transporter of coenzyme A, FAD and NAD+
    • Agrimi G, et al. The human gene SLC25A17 encodes a peroxisomal transporter of coenzyme A, FAD and NAD+. Biochem J 2012; 443: 241–247.
    • (2012) Biochem J , vol.443 , pp. 241-247
    • Agrimi, G.1
  • 90
    • 18244393501 scopus 로고    scopus 로고
    • Structural basis for antagonist-mediated recruitment of nuclear corepressors by PPARalpha
    • Xu HE, et al. Structural basis for antagonist-mediated recruitment of nuclear corepressors by PPARalpha. Nature 2002; 415: 813–817.
    • (2002) Nature , vol.415 , pp. 813-817
    • Xu, H.E.1
  • 91
    • 0032553542 scopus 로고    scopus 로고
    • Crystal structure of the ligand binding domain of the human nuclear receptor PPARgamma
    • Uppenberg J, et al. Crystal structure of the ligand binding domain of the human nuclear receptor PPARgamma. J Biol Chem 1998; 273: 31108–31112.
    • (1998) J Biol Chem , vol.273 , pp. 31108-31112
    • Uppenberg, J.1
  • 92
    • 0033105510 scopus 로고    scopus 로고
    • Molecular recognition of fatty acids by peroxisome proliferator-activated receptors
    • Xu HE, et al. Molecular recognition of fatty acids by peroxisome proliferator-activated receptors. Mol Cell 1999; 3: 397–403.
    • (1999) Mol Cell , vol.3 , pp. 397-403
    • Xu, H.E.1
  • 93
    • 9744235043 scopus 로고    scopus 로고
    • Diet, fatty acids, and regulation of genes important for heart disease
    • Vanden Heuvel JP. Diet, fatty acids, and regulation of genes important for heart disease. Curr Atheroscler Rep 2004; 6: 432–440.
    • (2004) Curr Atheroscler Rep , vol.6 , pp. 432-440
    • Vanden Heuvel, J.P.1
  • 94
    • 4644231528 scopus 로고    scopus 로고
    • Nuclear receptor signaling and cardiac energetics
    • Huss JM, Kelly DP. Nuclear receptor signaling and cardiac energetics. Circ Res 2004; 95: 568–578.
    • (2004) Circ Res , vol.95 , pp. 568-578
    • Huss, J.M.1    Kelly, D.P.2
  • 95
    • 67849134883 scopus 로고    scopus 로고
    • Differential effects of chronic, in vivo, PPAR’s stimulation on the myocardial subcellular redistribution of FAT/CD36 and FABPpm
    • Kalinowska A, et al. Differential effects of chronic, in vivo, PPAR’s stimulation on the myocardial subcellular redistribution of FAT/CD36 and FABPpm. FEBS Lett 2009; 583: 2527–2534.
    • (2009) FEBS Lett , vol.583 , pp. 2527-2534
    • Kalinowska, A.1
  • 96
    • 77954385136 scopus 로고    scopus 로고
    • Peroxisome proliferator activated receptor alpha (PPARalpha) and PPAR gamma coactivator (PGC-1alpha) induce carnitine palmitoyltransferase IA (CPT-1A) via independent gene elements
    • Song S, et al. Peroxisome proliferator activated receptor alpha (PPARalpha) and PPAR gamma coactivator (PGC-1alpha) induce carnitine palmitoyltransferase IA (CPT-1A) via independent gene elements. Mol Cell Endocrinol 2010; 325: 54–63.
    • (2010) Mol Cell Endocrinol , vol.325 , pp. 54-63
    • Song, S.1
  • 97
    • 0032699670 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting
    • Kersten S, et al. Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting. J Clin Invest 1999; 103: 1489–1498.
    • (1999) J Clin Invest , vol.103 , pp. 1489-1498
    • Kersten, S.1
  • 98
    • 79955104006 scopus 로고    scopus 로고
    • The Peroxisomal 3-keto-acyl-CoA thiolase B Gene Expression Is under the Dual Control of PPARalpha and HNF4alpha in the Liver
    • Chamouton J, et al. The Peroxisomal 3-keto-acyl-CoA thiolase B Gene Expression Is under the Dual Control of PPARalpha and HNF4alpha in the Liver. PPAR Res 2010; 2010: 352957.
    • (2010) PPAR Res , vol.2010
    • Chamouton, J.1
  • 99
    • 84878888472 scopus 로고    scopus 로고
    • Differential activation of catalase expression and activity by PPAR agonists: Implications for astrocyte protection in anti-glioma therapy
    • Khoo NK, et al. Differential activation of catalase expression and activity by PPAR agonists: Implications for astrocyte protection in anti-glioma therapy. Redox Biol 2013; 1: 70–79.
    • (2013) Redox Biol , vol.1 , pp. 70-79
    • Khoo, N.K.1
  • 100
    • 0036198223 scopus 로고    scopus 로고
    • Conditional inactivation of the peroxisome biogenesis Pex13 gene by Cre-loxP excision
    • Bjorkman J, et al. Conditional inactivation of the peroxisome biogenesis Pex13 gene by Cre-loxP excision. Genesis 2002; 32: 179–180.
    • (2002) Genesis , vol.32 , pp. 179-180
    • Bjorkman, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.