Phytanic acid disturbs mitochondrial homeostasis in heart of young rats: A possible pathomechanism of cardiomyopathy in Refsum disease

Molecular and Cellular Biochemistry

Volumn 366, Issue 1-2, 2012, Pages 335-343

  Grings, Mateus ^a   Tonin, Anelise Miotti ^a   Knebel, Lisiane Aurélio ^a   Zanatta, Ângela ^a   Moura, Alana Pimentel ^a   Filho, Carlos Severo Dutra ^a   Wajner, Moacir ^a,b   Leipnitz, Guilhian ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b HOSPITAL DE CLÍNICAS DE PORTO ALEGRE   (Brazil)

Author keywords

Heart; Oxidative stress; Phytanic acid; Refsum disease

Indexed keywords

CARBONYL DERIVATIVE; DICHLORODIHYDROFLUORESCEIN DIACETATE; FATTY ACID; GLUTATHIONE; LIPID; MELATONIN; N(G) NITROARGININE METHYL ESTER; PHYTANIC ACID; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TROLOX C;

ANIMAL TISSUE; ARTICLE; CARDIOMYOPATHY; CELL ENERGY; CONTROLLED STUDY; HEART MITOCHONDRION; HEART MUSCLE FIBER MEMBRANE POTENTIAL; HOMEOSTASIS; IN VITRO STUDY; METABOLIC INHIBITION; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PATHOGENESIS; RAT; REFSUM DISEASE;

ANIMALS; ANTIOXIDANTS; CARDIOMYOPATHIES; CHROMANS; ELECTRON TRANSPORT CHAIN COMPLEX PROTEINS; GLUTATHIONE; HOMEOSTASIS; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA, HEART; MYOCARDIUM; NADP; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE; OXIDATION-REDUCTION; OXIDATIVE STRESS; PHYTANIC ACID; PROTEIN CARBONYLATION; RATS; RATS, WISTAR; REFSUM DISEASE; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

RATTUS;

EID: 84862011841     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-012-1311-1     Document Type: Article

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