-
1
-
-
0032530765
-
A gender-related defect in lipid metabolism and glucose homeostasis in peroxisome proliferator- activated receptor alpha-deficient mice
-
Djouadi F, Weinheimer CJ, Saffitz JE, Pitchford C, Bastin J, Gonzalez FJ, Kelly DP. A gender-related defect in lipid metabolism and glucose homeostasis in peroxisome proliferator- activated receptor alpha-deficient mice. J Clin Invest. 1998;102:1083-1091.
-
(1998)
J Clin Invest
, vol.102
, pp. 1083-1091
-
-
Djouadi, F.1
Weinheimer, C.J.2
Saffitz, J.E.3
Pitchford, C.4
Bastin, J.5
Gonzalez, F.J.6
Kelly, D.P.7
-
2
-
-
0037459358
-
Peroxisome proliferator-acti-vated receptor (PPAR) alpha and PPARbeta/delta, but not PPARgamma, modulate the expression of genes involved in cardiac lipid metabolism
-
Gilde AJ, van der Lee KA, Willemsen PH, Chinetti G, van der Leij FR, van der Vusse GJ, Staels B, van Bilsen M. Peroxisome proliferator-acti-vated receptor (PPAR) alpha and PPARbeta/delta, but not PPARgamma, modulate the expression of genes involved in cardiac lipid metabolism. Circ Res. 2003;92:518-524.
-
(2003)
Circ Res
, vol.92
, pp. 518-524
-
-
Gilde, A.J.1
Van Der Lee, K.A.2
Willemsen, P.H.3
Chinetti, G.4
Van Der Leij, F.R.5
Van Der Vusse, G.J.6
Staels, B.7
Van Bilsen, M.8
-
3
-
-
0345735302
-
Peroxisome proliferator-activated receptor delta activates fatty acid oxidation in cultured neonatal and adult cardiomyocytes
-
Cheng L, Ding G, Qin Q, Xiao Y, Woods D, Chen YE, Yang Q. Peroxisome proliferator-activated receptor delta activates fatty acid oxidation in cultured neonatal and adult cardiomyocytes. Biochem Biophys Res Commun. 2004;313:277-286.
-
(2004)
Biochem Biophys Res Commun
, vol.313
, pp. 277-286
-
-
Cheng, L.1
Ding, G.2
Qin, Q.3
Xiao, Y.4
Woods, D.5
Chen, Y.E.6
Yang, Q.7
-
4
-
-
9144262378
-
Cardiomyocyte-restricted peroxisome proliferator-activated receptor-delta deletion perturbs myocardial fatty acid oxidation and leads to cardiomyopathy
-
Cheng L, Ding G, Qin Q, Huang Y, Lewis W, He N, Evans RM, Schneider MD, Brako FA, Xiao Y, Chen YE, Yang Q. Cardiomyocyte-restricted peroxisome proliferator-activated receptor-delta deletion perturbs myocardial fatty acid oxidation and leads to cardiomyopathy. Nat Med. 2004;10:1245-1250.
-
(2004)
Nat Med
, vol.10
, pp. 1245-1250
-
-
Cheng, L.1
Ding, G.2
Qin, Q.3
Huang, Y.4
Lewis, W.5
He, N.6
Evans, R.M.7
Schneider, M.D.8
Brako, F.A.9
Xiao, Y.10
Chen, Y.E.11
Yang, Q.12
-
5
-
-
36849068108
-
Nuclear receptors PPARbeta/delta and PPARalpha direct distinct metabolic regulatory programs in the mouse heart
-
Burkart EM, Sambandam N, Han X, Gross RW, Courtois M, Gierasch CM, Shoghi K, Welch MJ, Kelly DP. Nuclear receptors PPARbeta/delta and PPARalpha direct distinct metabolic regulatory programs in the mouse heart. J Clin Invest. 2007;117:3930-3939.
-
(2007)
J Clin Invest
, vol.117
, pp. 3930-3939
-
-
Burkart, E.M.1
Sambandam, N.2
Han, X.3
Gross, R.W.4
Courtois, M.5
Gierasch, C.M.6
Shoghi, K.7
Welch, M.J.8
Kelly, D.P.9
-
6
-
-
34948910262
-
Cardiomyocyte expression of PPARgamma leads to cardiac dysfunction in mice
-
Son NH, Park TS, Yamashita H, Yokoyama M, Huggins LA, Okajima K, Homma S, Szabolcs MJ, Huang LS, Goldberg IJ. Cardiomyocyte expression of PPARgamma leads to cardiac dysfunction in mice. J Clin Invest. 2007;117:2791-2801.
-
(2007)
J Clin Invest
, vol.117
, pp. 2791-2801
-
-
Son, N.H.1
Park, T.S.2
Yamashita, H.3
Yokoyama, M.4
Huggins, L.A.5
Okajima, K.6
Homma, S.7
Szabolcs, M.J.8
Huang, L.S.9
Goldberg, I.J.10
-
7
-
-
69249212275
-
High-fat feeding in cardiomyocyte-restricted PPARdelta knockout mice leads to cardiac overexpression of lipid metabolic genes but fails to rescue cardiac phenotypes
-
Li Y, Cheng L, Qin Q, Liu J, Lo WK, Brako LA, Yang Q. High-fat feeding in cardiomyocyte-restricted PPARdelta knockout mice leads to cardiac overexpression of lipid metabolic genes but fails to rescue cardiac phenotypes. J Mol Cell Cardiol. 2009;47:536-543.
-
(2009)
J Mol Cell Cardiol
, vol.47
, pp. 536-543
-
-
Li, Y.1
Cheng, L.2
Qin, Q.3
Liu, J.4
Lo, W.K.5
Brako, L.A.6
Yang, Q.7
-
8
-
-
67349140952
-
Peroxisome proliferator-activated receptor delta regulates mitofusin 2 expression in the heart
-
Li Y, Yin R, Liu J, Wang P, Wu S, Luo J, Zhelyabovska O, Yang Q. Peroxisome proliferator-activated receptor delta regulates mitofusin 2 expression in the heart. J Mol Cell Cardiol. 2009;46:876-882.
-
(2009)
J Mol Cell Cardiol
, vol.46
, pp. 876-882
-
-
Li, Y.1
Yin, R.2
Liu, J.3
Wang, P.4
Wu, S.5
Luo, J.6
Zhelyabovska, O.7
Yang, Q.8
-
9
-
-
33845331405
-
Open-chest 31P magnetic resonance spectroscopy of mouse heart at 4.7 Tesla
-
Lee J, Hu Q, Nakamura Y, Wang X, Zhang X, Zhu X, Chen W, Yang Q, Zhang J. Open-chest 31P magnetic resonance spectroscopy of mouse heart at 4.7 Tesla. J Magn Reson Imaging. 2006;24:1269-1276.
-
(2006)
J Magn Reson Imaging
, vol.24
, pp. 1269-1276
-
-
Lee, J.1
Hu, Q.2
Nakamura, Y.3
Wang, X.4
Zhang, X.5
Zhu, X.6
Chen, W.7
Yang, Q.8
Zhang, J.9
-
10
-
-
77950874188
-
Peroxisome proliferator-activated receptor {delta} is an essential transcriptional regulator for mitochondrial protection and biogenesis in adult heart
-
Wang P, Liu J, Li Y, Wu S, Luo J, Yang H, Subbiah R, Chatham J, Zhelyabovska O, Yang Q. Peroxisome proliferator-activated receptor {delta} is an essential transcriptional regulator for mitochondrial protection and biogenesis in adult heart. Circ Res. 2010;19:106:911-919.
-
(2010)
Circ Res
, vol.19
, Issue.106
, pp. 911-919
-
-
Wang, P.1
Liu, J.2
Li, Y.3
Wu, S.4
Luo, J.5
Yang, H.6
Subbiah, R.7
Chatham, J.8
Zhelyabovska, O.9
Yang, Q.10
-
11
-
-
33644660537
-
PGC-1 coactivators: Inducible regulators of energy metabolism in health and disease
-
Finck BN, Kelly DP. PGC-1 coactivators: Inducible regulators of energy metabolism in health and disease. J Clin Invest. 2006;116:615-622.
-
(2006)
J Clin Invest
, vol.116
, pp. 615-622
-
-
Finck, B.N.1
Kelly, D.P.2
-
12
-
-
47949104798
-
The role of exercise and PGC1alpha in inflammation and chronic disease
-
Handschin C, Spiegelman BM. The role of exercise and PGC1alpha in inflammation and chronic disease. Nature. 2008;454:463-469.
-
(2008)
Nature
, vol.454
, pp. 463-469
-
-
Handschin, C.1
Spiegelman, B.M.2
-
13
-
-
24144463983
-
Metabolic control through the PGC-1 family of transcription coactivators
-
Lin J, Handschin C, Spiegelman BM. Metabolic control through the PGC-1 family of transcription coactivators. Cell Metab. 2005;1:361-370.
-
(2005)
Cell Metab
, vol.1
, pp. 361-370
-
-
Lin, J.1
Handschin, C.2
Spiegelman, B.M.3
-
15
-
-
42049114034
-
Transcriptional paradigms in mammalian mitochondrial biogenesis and function
-
Scarpulla RC. Transcriptional paradigms in mammalian mitochondrial biogenesis and function. Physiol Rev. 2008;88:611-638.
-
(2008)
Physiol Rev
, vol.88
, pp. 611-638
-
-
Scarpulla, R.C.1
-
16
-
-
8844276054
-
Regulation of muscle fiber type and running endurance by ppardelta
-
Wang YX, Zhang CL, Yu RT, Cho HK, Nelson MC, Bayuga-Ocampo CR, Ham J, Kang H, Evans RM. Regulation of muscle fiber type and running endurance by ppardelta. PLoS Biol. 2004;2:e294.
-
(2004)
PLoS Biol
, vol.2
-
-
Wang, Y.X.1
Zhang, C.L.2
Yu, R.T.3
Cho, H.K.4
Nelson, M.C.5
Bayuga-Ocampo, C.R.6
Ham, J.7
Kang, H.8
Evans, R.M.9
-
17
-
-
33750427891
-
PGC1alpha expression is controlled in skeletal muscles by PPARbeta, whose ablation results in fiber-type switching, obesity, and type 2 diabetes
-
Schuler M, Ali F, Chambon C, Duteil D, Bornert JM, Tardivel A, Desvergne B, Wahli W, Chambon P, Metzger D. PGC1alpha expression is controlled in skeletal muscles by PPARbeta, whose ablation results in fiber-type switching, obesity, and type 2 diabetes. Cell Metab. 2006;4: 407-414.
-
(2006)
Cell Metab
, vol.4
, pp. 407-414
-
-
Schuler, M.1
Ali, F.2
Chambon, C.3
Duteil, D.4
Bornert, J.M.5
Tardivel, A.6
Desvergne, B.7
Wahli, W.8
Chambon, P.9
Metzger, D.10
-
18
-
-
0018667723
-
Assignment of the gene for cytoplasmic superoxide dismutase (SOD-1) to a region of chromosome 16 and of hprt to a region of the x chromosome in the mouse
-
Francke U, Taggart RT. Assignment of the gene for cytoplasmic superoxide dismutase (SOD-1) to a region of chromosome 16 and of hprt to a region of the x chromosome in the mouse. Proc Natl Acad Sci USA. 1979;76:5230-5233.
-
(1979)
Proc Natl Acad Sci USA
, vol.76
, pp. 5230-5233
-
-
Francke, U.1
Taggart, R.T.2
-
19
-
-
0033008702
-
Induction of the rat Cu/Zn superoxide dismutase gene through the peroxisome proliferator-responsive element by arachidonic acid
-
Yoo HY, Chang MS, Rho HM. Induction of the rat Cu/Zn superoxide dismutase gene through the peroxisome proliferator-responsive element by arachidonic acid. Gene. 1999;234:87-91.
-
(1999)
Gene
, vol.234
, pp. 87-91
-
-
Yoo, H.Y.1
Chang, M.S.2
Rho, H.M.3
-
20
-
-
0036908619
-
Identification of a functional peroxisome proliferator-activated receptor response element in the rat catalase promoter
-
Girnun GD, Domann FE, Moore SA, Robbins ME. Identification of a functional peroxisome proliferator-activated receptor response element in the rat catalase promoter. Mol Endocrinol. 2002;16:2793-2801.
-
(2002)
Mol Endocrinol
, vol.16
, pp. 2793-2801
-
-
Girnun, G.D.1
Domann, F.E.2
Moore, S.A.3
Robbins, M.E.4
-
21
-
-
0033803048
-
Peroxisome proliferator-activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis
-
Lehman JJ, Barger PM, Kovacs A, Saffitz JE, Medeiros DM, Kelly DP. Peroxisome proliferator-activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis. J Clin Invest. 2000;106: 847-856.
-
(2000)
J Clin Invest
, vol.106
, pp. 847-856
-
-
Lehman, J.J.1
Barger, P.M.2
Kovacs, A.3
Saffitz, J.E.4
Medeiros, D.M.5
Kelly, D.P.6
-
22
-
-
33846890004
-
PPARdelta, but not PPARalpha, activates PGC-1alpha gene transcription in muscle
-
Hondares E, Pineda-Torra I, Iglesias R, Staels B, Villarroya F, Giralt M. PPARdelta, but not PPARalpha, activates PGC-1alpha gene transcription in muscle. Biochem Biophys Res Commun. 2007;354:1021-1027.
-
(2007)
Biochem Biophys Res Commun
, vol.354
, pp. 1021-1027
-
-
Hondares, E.1
Pineda-Torra, I.2
Iglesias, R.3
Staels, B.4
Villarroya, F.5
Giralt, M.6
-
23
-
-
0027934994
-
Study of 5'-flanking region of human Cu/Zn superoxide dismutase
-
Kim HT, Kim YH, Nam JW, Lee HJ, Rho HM, Jung G. Study of 5'-flanking region of human Cu/Zn superoxide dismutase. Biochem Biophys Res Commun. 1994;201:1526-1533.
-
(1994)
Biochem Biophys Res Commun
, vol.201
, pp. 1526-1533
-
-
Kim, H.T.1
Kim, Y.H.2
Nam, J.W.3
Lee, H.J.4
Rho, H.M.5
Jung, G.6
-
24
-
-
36649035297
-
Cardiac peroxisome proliferator-activated receptor gamma is essential in protecting car-diomyocytes from oxidative damage
-
Ding G, Fu M, Qin Q, Lewis W, Kim HW, Fukai T, Bacanamwo M, Chen YE, Schneider MD, Mangelsdorf DJ, Evans RM, Yang Q. Cardiac peroxisome proliferator-activated receptor gamma is essential in protecting car-diomyocytes from oxidative damage. Cardiovasc Res. 2007;76:269-279.
-
(2007)
Cardiovasc Res
, vol.76
, pp. 269-279
-
-
Ding, G.1
Fu, M.2
Qin, Q.3
Lewis, W.4
Kim, H.W.5
Fukai, T.6
Bacanamwo, M.7
Chen, Y.E.8
Schneider, M.D.9
Mangelsdorf, D.J.10
Evans, R.M.11
Yang, Q.12
-
25
-
-
30744460411
-
Peroxisome proliferator-activated receptor delta (PPARdelta) activation protects H9c2 cardiomyoblasts from oxidative stress-induced apoptosis
-
Pesant M, Sueur S, Dutartre P, Tallandier M, Grimaldi PA, Rochette L, Connat JL. Peroxisome proliferator-activated receptor delta (PPARdelta) activation protects H9c2 cardiomyoblasts from oxidative stress-induced apoptosis. Cardiovasc Res. 2006;69:440-449.
-
(2006)
Cardiovasc Res
, vol.69
, pp. 440-449
-
-
Pesant, M.1
Sueur, S.2
Dutartre, P.3
Tallandier, M.4
Grimaldi, P.A.5
Rochette, L.6
Connat, J.L.7
-
26
-
-
0035957375
-
Restoration of insulin-sensitive glucose transporter (GLUT4) gene expression in muscle cells by the transcriptional coactivator PGC-1
-
Michael LF, Wu Z, Cheatham RB, Puigserver P, Adelmant G, Lehman JJ, Kelly DP, Spiegelman BM. Restoration of insulin-sensitive glucose transporter (GLUT4) gene expression in muscle cells by the transcriptional coactivator PGC-1. Proc Natl Acad Sci USA. 2001;98:3820-3825.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 3820-3825
-
-
Michael, L.F.1
Wu, Z.2
Cheatham, R.B.3
Puigserver, P.4
Adelmant, G.5
Lehman, J.J.6
Kelly, D.P.7
Spiegelman, B.M.8
-
27
-
-
0037022592
-
The peroxisome proliferator-activated receptor delta, an integrator of transcriptional repression and nuclear receptor signaling
-
Shi Y, Hon M, Evans RM. The peroxisome proliferator-activated receptor delta, an integrator of transcriptional repression and nuclear receptor signaling. Proc Natl Acad Sci USA. 2002;99:2613-2618.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 2613-2618
-
-
Shi, Y.1
Hon, M.2
Evans, R.M.3
-
28
-
-
70349492462
-
Ligand modulated antagonism of PPARgamma by genomic and non-genomic actions of ppardelta
-
Gustafsson MC, Knight D, Palmer CN. Ligand modulated antagonism of PPARgamma by genomic and non-genomic actions of ppardelta. PLoS ONE. 2009;4:e7046.
-
(2009)
PLoS ONE
, vol.4
-
-
Gustafsson, M.C.1
Knight, D.2
Palmer, C.N.3
-
29
-
-
0037453718
-
Peroxisome-proliferator-activated receptor delta activates fat metabolism to prevent obesity
-
Wang YX, Lee CH, Tiep S, Yu RT, Ham J, Kang H, Evans RM. Peroxisome-proliferator-activated receptor delta activates fat metabolism to prevent obesity. Cell. 2003;113:159-170.
-
(2003)
Cell
, vol.113
, pp. 159-170
-
-
Wang, Y.X.1
Lee, C.H.2
Tiep, S.3
Yu, R.T.4
Ham, J.5
Kang, H.6
Evans, R.M.7
-
30
-
-
33644644271
-
Alterations in skin and stratified epithelia by constitutively activated PPARalpha
-
Yang Q, Yamada A, Kimura S, Peters JM, Gonzalez FJ. Alterations in skin and stratified epithelia by constitutively activated PPARalpha. J Invest Dermatol. 2006;126:374-385.
-
(2006)
J Invest Dermatol
, vol.126
, pp. 374-385
-
-
Yang, Q.1
Yamada, A.2
Kimura, S.3
Peters, J.M.4
Gonzalez, F.J.5
-
31
-
-
77954576474
-
Estrogen-related receptor gamma is a key regulator of muscle mitochondrial activity and oxidative capacity
-
Rangwala SM, Wang X, Calvo JA, Lindsley L, Zhang Y, Deyneko G, Beaulieu V, Gao J, Turner G, Markovits J. Estrogen-related receptor gamma is a key regulator of muscle mitochondrial activity and oxidative capacity. J Biol Chem. 2010;285:22619-22629.
-
(2010)
J Biol Chem
, vol.285
, pp. 22619-22629
-
-
Rangwala, S.M.1
Wang, X.2
Calvo, J.A.3
Lindsley, L.4
Zhang, Y.5
Deyneko, G.6
Beaulieu, V.7
Gao, J.8
Turner, G.9
Markovits, J.10
-
32
-
-
78651346813
-
Intestinal specific lxr activation stimulates reverse cholesterol transport and protects from atherosclerosis
-
Lo Sasso G, Murzilli S, Salvatore L, D'Errico I, Petruzzelli M, Conca P, Jiang ZY, Calabresi L, Parini P, Moschetta A. Intestinal specific lxr activation stimulates reverse cholesterol transport and protects from atherosclerosis. Cell Metab. 12:187-193.
-
Cell Metab
, vol.12
, pp. 187-193
-
-
Lo Sasso, G.1
Murzilli, S.2
Salvatore, L.3
D'Errico, I.4
Petruzzelli, M.5
Conca, P.6
Jiang, Z.Y.7
Calabresi, L.8
Parini, P.9
Moschetta, A.10
-
33
-
-
67949100572
-
Avoidance of transient cardiomyopathy in car-diomyocyte-targeted tamoxifen-induced MerCreMer gene deletion models
-
Koitabashi N, Bedja D, Zaiman AL, Pinto YM, Zhang M, Gabrielson KL, Takimoto E, Kass DA. Avoidance of transient cardiomyopathy in car-diomyocyte-targeted tamoxifen-induced MerCreMer gene deletion models. Circ Res. 2009;105:12-15.
-
(2009)
Circ Res
, vol.105
, pp. 12-15
-
-
Koitabashi, N.1
Bedja, D.2
Zaiman, A.L.3
Pinto, Y.M.4
Zhang, M.5
Gabrielson, K.L.6
Takimoto, E.7
Kass, D.A.8
-
34
-
-
77954537139
-
Tamoxifen administration routes and dosage for inducible Cre-mediated gene disruption in mouse hearts
-
Andersson KB, Winer LH, Mørk HK, Molkentin JD, Jaisser F. Tamoxifen administration routes and dosage for inducible Cre-mediated gene disruption in mouse hearts. Transgenic Res. 2010;19:715-725.
-
(2010)
Transgenic Res
, vol.19
, pp. 715-725
-
-
Andersson, K.B.1
Winer, L.H.2
Mørk, H.K.3
Molkentin, J.D.4
Jaisser, F.5
|