Conversion of solid dispersion prepared by acid-base interaction into free-flowing and tabletable powder by using Neusilin® US2

International Journal of Pharmaceutics

Volumn 484, Issue 1-2, 2015, Pages 172-180

  Shah, Ankita ^a   Serajuddin, Abu T M ^a  

^a ST JOHN'S UNIVERSITY   (United States)

Author keywords

Amorphous solid dispersion; Haloperidol; Neusilin US2; Poorly water soluble drug; Supersolubilization; Weak organic acid

Indexed keywords

ATTAPULGITE; CARBOXYLIC ACID DERIVATIVE; CITRIC ACID; HALOPERIDOL; MALIC ACID; TARTARIC ACID; ALUMINUM DERIVATIVE; MAGNESIUM DERIVATIVE; PHARMACEUTICAL VEHICLES AND ADDITIVES; POWDER; SILICATE; TABLET;

AQUEOUS SOLUTION; ARTICLE; BULK DENSITY; CONTROLLED STUDY; CRYSTALLIZATION; DENSITY; DIFFERENTIAL SCANNING CALORIMETRY; DISPERSION; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG SOLUBILITY; DRUG STABILITY; FLOW KINETICS; PARTICLE SIZE; PH; PHYSICAL CHEMISTRY; POWDER; PRIORITY JOURNAL; SOLID STATE; TABLET; TABLET FORMULATION; TABLET PROPERTY; TAP DENSITY; X RAY POWDER DIFFRACTION; CHEMISTRY; MEDICINAL CHEMISTRY; PROCEDURES; SOLUBILITY; SYNTHESIS; X RAY DIFFRACTION;

ALUMINUM COMPOUNDS; CHEMISTRY, PHARMACEUTICAL; HALOPERIDOL; HYDROGEN-ION CONCENTRATION; MAGNESIUM COMPOUNDS; PHARMACEUTIC AIDS; POWDERS; SILICATES; SOLUBILITY; TABLETS; X-RAY DIFFRACTION;

EID: 84923928603     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2015.02.060     Document Type: Article

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