Enhanced drug dissolution and bulk properties of solid dispersions granulated with a surface adsorbent

Pharmaceutical Development and Technology

Volumn 6, Issue 4, 2001, Pages 563-572

  Gupta, Manish K ^a   Goldman, David ^b   Bogner, Robin H ^a   Tseng, Yin Chao ^b  

^a UNIVERSITY OF CONNECTICUT   (United States)

^b BAYER CORPORATION   (United States)

Author keywords

Dissolution; Gelucire; Hot melt granulation; Neusilin; Solid dispersion; Tablets

Indexed keywords

ATTAPULGITE; GELUCIRE; SURFACTANT; TANOMASTAT;

ADSORPTION; ARTICLE; BIOAVAILABILITY; DISPERSION; DRUG DOSAGE FORM; DRUG FORMULATION; DRUG GRANULE; DRUG SOLUBILITY; PRIORITY JOURNAL; SURFACE PROPERTY; TABLET DISINTEGRATION;

ADSORPTION; ANTINEOPLASTIC AGENTS; CHEMISTRY, PHARMACEUTICAL; COMPRESSIVE STRENGTH; FATS; OILS; ORGANIC CHEMICALS; SOLUBILITY; SURFACE PROPERTIES; TABLETS; WATER;

EID: 0035667509     PISSN: 10837450     EISSN: None     Source Type: Journal    
DOI: 10.1081/PDT-120000294     Document Type: Article

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8. Bioavailability of a poorly water-soluble drug from tablet and solid dispersion in humans
9. Physicochemical characterization of solid dispersions of the antiviral agent UC 781 with polyethylene glycol 6000 and gelucire 44/14
10. Solidification studies of polyethylene glycols, gelucire 44/14 or their dispersions with triamterene or temazepam
11. Evaluating flow properties of solids