Formation of physically stable amorphous drugs by milling with neusilin

Journal of Pharmaceutical Sciences

Volumn 92, Issue 3, 2003, Pages 536-551

  Gupta, Manish K ^a   Vanwert, Adam ^b   Bogner, Robin H ^a  

^a UNIVERSITY OF CONNECTICUT   (United States)

^b WILKES UNIVERSITY   (United States)

Author keywords

Acid base reaction; Amorphization; Ball milling; Hydrogen bonding; Physical stability

Indexed keywords

ATTAPULGITE; CARBOXYLIC ACID; INDOMETACIN; KETOPROFEN; NAPROXEN; NEUSILIN; PROGESTERONE; SODIUM CHLORIDE; WATER;

ACID BASE BALANCE; ADSORPTION; ARTICLE; BIREFRINGENCE; DIFFERENTIAL SCANNING CALORIMETRY; DRUG BINDING; DRUG FORMULATION; DRUG STABILITY; DRUG STORAGE; HYDROGEN BOND; INFRARED SPECTROSCOPY; POWDER; REDUCTION; TEMPERATURE DEPENDENCE; X RAY POWDER DIFFRACTION;

EID: 0037369754     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1002/jps.10308     Document Type: Article

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