메뉴 건너뛰기




Volumn 164, Issue , 2015, Pages 301-308

Scutellarin protects against the liver injury induced by diosbulbin B in mice and its mechanism

Author keywords

Anti tumor; Diosbulbin B; Hepatotoxicity; Inflammation; Oxidativestressinjury; Scutellarin

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; DIOSBULBIN B; DITERPENE; FLUOROURACIL; GAMMA INTERFERON; GLUTATHIONE; GLUTATHIONE PEROXIDASE; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; MALONALDEHYDE; MYELOPEROXIDASE; SCUTELLARIN; SYNAPTOTAGMIN I; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; APIGENIN; CYTOKINE; FUSED HETEROCYCLIC RINGS; GLUCURONIC ACID; PROTECTIVE AGENT;

EID: 84923899917     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2015.02.031     Document Type: Article
Times cited : (50)

References (47)
  • 1
    • 0023724778 scopus 로고
    • I kappa B: A specific inhibitor of the NF-kappa B transcription factor
    • P.A. Baeuerle, and D. Baltimore I kappa B: a specific inhibitor of the NF-kappa B transcription factor Science 242 1988 540 546
    • (1988) Science , vol.242 , pp. 540-546
    • Baeuerle, P.A.1    Baltimore, D.2
  • 2
    • 0028174061 scopus 로고
    • Function and activation of NF-kappa B in the immune system
    • P.A. Baeuerle, and T. Henkel Function and activation of NF-kappa B in the immune system Annual Review Immunology 12 1994 141 179
    • (1994) Annual Review Immunology , vol.12 , pp. 141-179
    • Baeuerle, P.A.1    Henkel, T.2
  • 3
    • 68549130601 scopus 로고    scopus 로고
    • Scutellarin sensitizes drug-evoked colon cancer cell apoptosis through enhanced caspase-6 activation
    • J.Y. Chan, B.K. Tan, and S.C. Lee Scutellarin sensitizes drug-evoked colon cancer cell apoptosis through enhanced caspase-6 activation Anticancer Research 29 2009 3043 3047
    • (2009) Anticancer Research , vol.29 , pp. 3043-3047
    • Chan, J.Y.1    Tan, B.K.2    Lee, S.C.3
  • 4
    • 84885628465 scopus 로고    scopus 로고
    • Scutellarin attenuates hypertension-induced expression of brain Toll-like receptor 4/nuclear factor kappa B
    • X. Chen, X. Shi, X. Zhang, H. Lei, S. Long, H. Su, Z. Pei, and R. Huang Scutellarin attenuates hypertension-induced expression of brain Toll-like receptor 4/nuclear factor kappa B Mediators of Inflammation 2013 2013 432623
    • (2013) Mediators of Inflammation , vol.2013 , pp. 432623
    • Chen, X.1    Shi, X.2    Zhang, X.3    Lei, H.4    Long, S.5    Su, H.6    Pei, Z.7    Huang, R.8
  • 6
    • 2542530655 scopus 로고    scopus 로고
    • Antagonistic effect of scutellarin on the toxicity of selenium in rat livers
    • A.A. Eltayeb, Q. Liu, L. Gan, H. Liu, and H. Xu Antagonistic effect of scutellarin on the toxicity of selenium in rat livers Biological Trace Element Research 98 2004 253 264
    • (2004) Biological Trace Element Research , vol.98 , pp. 253-264
    • Eltayeb, A.A.1    Liu, Q.2    Gan, L.3    Liu, H.4    Xu, H.5
  • 7
    • 84868365866 scopus 로고    scopus 로고
    • Novel function of scutellarin in inhibiting cell proliferation and inducing cell apoptosis of human Burkitt lymphoma Namalwa cells
    • Y. Feng, S. Zhang, J. Tu, Z. Cao, Y. Pan, B. Shang, R. Liu, M. Bao, P. Guo, and Q. Zhou Novel function of scutellarin in inhibiting cell proliferation and inducing cell apoptosis of human Burkitt lymphoma Namalwa cells Leukemia & Lymphoma 53 2012 2456 2464
    • (2012) Leukemia & Lymphoma , vol.53 , pp. 2456-2464
    • Feng, Y.1    Zhang, S.2    Tu, J.3    Cao, Z.4    Pan, Y.5    Shang, B.6    Liu, R.7    Bao, M.8    Guo, P.9    Zhou, Q.10
  • 8
    • 84855221555 scopus 로고    scopus 로고
    • Hepatoprotective effect of coenzyme Q10 in rats with acetaminophen toxicity
    • A.A. Fouad, and I. Jresat Hepatoprotective effect of coenzyme Q10 in rats with acetaminophen toxicity Environmental Toxicology and Pharmacology 33 2012 158 167
    • (2012) Environmental Toxicology and Pharmacology , vol.33 , pp. 158-167
    • Fouad, A.A.1    Jresat, I.2
  • 10
    • 57649155739 scopus 로고    scopus 로고
    • Protection of acetaminophen induced mitochondrial dysfunctions and hepatic necrosis via Akt-NF-kappaB pathway: Role of a novel plant protein
    • A. Ghosh, and P.C. Sil Protection of acetaminophen induced mitochondrial dysfunctions and hepatic necrosis via Akt-NF-kappaB pathway: role of a novel plant protein Chemico-Biological Interactions 177 2009 96 106
    • (2009) Chemico-Biological Interactions , vol.177 , pp. 96-106
    • Ghosh, A.1    Sil, P.C.2
  • 12
    • 84878355386 scopus 로고    scopus 로고
    • The neurotoxicity of β-amyloid peptide toward rat brain is associated with enhanced oxidative stress, inflammation and apoptosis, all of which can be attenuated by scutellarin
    • L.L. Guo, Z.Z. Guan, Y. Huang, Y.L. Wang, and J.S. Shi The neurotoxicity of β-amyloid peptide toward rat brain is associated with enhanced oxidative stress, inflammation and apoptosis, all of which can be attenuated by scutellarin Experimental and Toxicologic Pathology 65 2013 579 584
    • (2013) Experimental and Toxicologic Pathology , vol.65 , pp. 579-584
    • Guo, L.L.1    Guan, Z.Z.2    Huang, Y.3    Wang, Y.L.4    Shi, J.S.5
  • 13
    • 0033566883 scopus 로고    scopus 로고
    • A myeloperoxidase-specific assay based upon bromide-dependent chemiluminescence of luminol
    • A.S. Haqqani, J.K. Sandhu, and H.C. Birnboim A myeloperoxidase-specific assay based upon bromide-dependent chemiluminescence of luminol Analytical Biochemistry 273 1999 126 132
    • (1999) Analytical Biochemistry , vol.273 , pp. 126-132
    • Haqqani, A.S.1    Sandhu, J.K.2    Birnboim, H.C.3
  • 14
    • 0022603846 scopus 로고
    • Determination of serum glutamate oxaloacetate transaminase and glutamate pyruvate transaminase by using l-glutamte oxidase
    • T. Kamei, K. Asano, and S. Nakamura Determination of serum glutamate oxaloacetate transaminase and glutamate pyruvate transaminase by using l-glutamte oxidase Chemical and Pharmaceutical Bulletin 34 1986 409 412
    • (1986) Chemical and Pharmaceutical Bulletin , vol.34 , pp. 409-412
    • Kamei, T.1    Asano, K.2    Nakamura, S.3
  • 15
    • 26444476026 scopus 로고    scopus 로고
    • New roles for an old selenoenzyme: Evidence from glutathione peroxidase-1 null and overexpressing mice
    • X.G. Lei, and W.H. Cheng New roles for an old selenoenzyme: evidence from glutathione peroxidase-1 null and overexpressing mice Journal of Nutrition 135 2005 2295 2298
    • (2005) Journal of Nutrition , vol.135 , pp. 2295-2298
    • Lei, X.G.1    Cheng, W.H.2
  • 16
    • 84875449915 scopus 로고    scopus 로고
    • Potentiation of scutellarin on human tongue carcinoma xenograft by low-intensity ultrasound
    • H. Li, H. Fan, Z. Wang, J. Zheng, and W. Cao Potentiation of scutellarin on human tongue carcinoma xenograft by low-intensity ultrasound PLoS One 8 2013 e59473
    • (2013) PLoS One , vol.8 , pp. e59473
    • Li, H.1    Fan, H.2    Wang, Z.3    Zheng, J.4    Cao, W.5
  • 17
    • 84876003632 scopus 로고    scopus 로고
    • Scutellarin inhibits the growth and invasion of human tongue squamous carcinoma through the inhibition of matrix metalloproteinase-2 and -9 and αvβ6 integrin
    • H. Li, D. Huang, Z. Gao, Y. Chen, L. Zhang, and J. Zheng Scutellarin inhibits the growth and invasion of human tongue squamous carcinoma through the inhibition of matrix metalloproteinase-2 and -9 and αvβ6 integrin International Journal of Oncology 42 2013 1674 1681
    • (2013) International Journal of Oncology , vol.42 , pp. 1674-1681
    • Li, H.1    Huang, D.2    Gao, Z.3    Chen, Y.4    Zhang, L.5    Zheng, J.6
  • 18
    • 78149328322 scopus 로고    scopus 로고
    • Scutellarion inhibits cell migration by regulating production of αvβ6 integrin and E-cadherin in human tongue cancer cells
    • H. Li, D. Huang, Z. Gao, Y. Lv, L. Zhang, H. Cui, and J. Zheng Scutellarion inhibits cell migration by regulating production of αvβ6 integrin and E-cadherin in human tongue cancer cells Oncology Research 24 2010 1153 1160
    • (2010) Oncology Research , vol.24 , pp. 1153-1160
    • Li, H.1    Huang, D.2    Gao, Z.3    Lv, Y.4    Zhang, L.5    Cui, H.6    Zheng, J.7
  • 19
    • 77953673125 scopus 로고    scopus 로고
    • Suppression of nuclear factor-kappa B activity in kupffer cells protects rat liver graft from ischemia-reperfusion injury
    • J.D. Li, Y. Peng, X.Y. Peng, Q.L. Li, and Q. Li Suppression of nuclear factor-kappa B activity in kupffer cells protects rat liver graft from ischemia-reperfusion injury Transplantation Proceedings 42 2010 1582 1586
    • (2010) Transplantation Proceedings , vol.42 , pp. 1582-1586
    • Li, J.D.1    Peng, Y.2    Peng, X.Y.3    Li, Q.L.4    Li, Q.5
  • 20
    • 80755163210 scopus 로고    scopus 로고
    • The difference of glutathione antioxidant system in newly weaned and young mice liver and its involvement in isoline-induced hepatotoxicity
    • Q.N. Liang, Y.C. Sheng, P. Jiang, L.L. Ji, Y.Y. Xia, Y. Min, and Z.T. Wang The difference of glutathione antioxidant system in newly weaned and young mice liver and its involvement in isoline-induced hepatotoxicity Archives of Toxicology 85 2011 1267 1279
    • (2011) Archives of Toxicology , vol.85 , pp. 1267-1279
    • Liang, Q.N.1    Sheng, Y.C.2    Jiang, P.3    Ji, L.L.4    Xia, Y.Y.5    Min, Y.6    Wang, Z.T.7
  • 21
    • 0242390471 scopus 로고    scopus 로고
    • Protective effects of scutellarin on superoxide-induced oxidative stress in rat cortical synaptosomes
    • H. Liu, X.L. Yang, Y. Wang, X.Q. Tang, D.Y. Jiang, and H.B. Xu Protective effects of scutellarin on superoxide-induced oxidative stress in rat cortical synaptosomes Acta Pharmacologica Sinica 24 2003 1113 1117
    • (2003) Acta Pharmacologica Sinica , vol.24 , pp. 1113-1117
    • Liu, H.1    Yang, X.L.2    Wang, Y.3    Tang, X.Q.4    Jiang, D.Y.5    Xu, H.B.6
  • 22
    • 84896874830 scopus 로고    scopus 로고
    • Two cases of toxic hepatitis caused by Dioscorea bulbifera L
    • J.R. Liu Two cases of toxic hepatitis caused by Dioscorea bulbifera L Adverse Drug Reactions Journal 2 2002 129 130
    • (2002) Adverse Drug Reactions Journal , vol.2 , pp. 129-130
    • Liu, J.R.1
  • 24
    • 0036582349 scopus 로고    scopus 로고
    • Pancreatic elastase induces liver injury by activating cytokine production within kupffer cells via nuclear factor-kappa B
    • M.M. Murr, J. Yang, A. Fier, P. Kaylor, S. Mastorides, and J.G. Norman Pancreatic elastase induces liver injury by activating cytokine production within kupffer cells via nuclear factor-kappa B Journal of Gastrointestinal Surgery 6 2002 474 480
    • (2002) Journal of Gastrointestinal Surgery , vol.6 , pp. 474-480
    • Murr, M.M.1    Yang, J.2    Fier, A.3    Kaylor, P.4    Mastorides, S.5    Norman, J.G.6
  • 25
    • 33645992924 scopus 로고
    • Diosbulbin D and 8-epidiosbulbin e acetate, norclerodane diterpenoids from Dioscorea bulbifera tubers
    • R.D.H. Murray, Z. Jorge, N.H. Khan, M. Shahjahan, and M. Quaisuddin Diosbulbin D and 8-epidiosbulbin E acetate, norclerodane diterpenoids from Dioscorea bulbifera tubers Phytochemistry 23 1984 623 625
    • (1984) Phytochemistry , vol.23 , pp. 623-625
    • Murray, R.D.H.1    Jorge, Z.2    Khan, N.H.3    Shahjahan, M.4    Quaisuddin, M.5
  • 26
    • 0036017172 scopus 로고    scopus 로고
    • Role of kupffer cells in alcoholic hepatitis
    • A.A. Nanji Role of kupffer cells in alcoholic hepatitis Alcohol 27 2002 13 15
    • (2002) Alcohol , vol.27 , pp. 13-15
    • Nanji, A.A.1
  • 29
    • 84900524575 scopus 로고    scopus 로고
    • Butyrate protects liver against ischemia reperfusion injury by inhibiting nuclear factor kappa B activation in kupffer cells
    • Y.L. Qiao, J.M. Qian, F.R. Wang, Z.Y. Ma, and Q.W. Wang Butyrate protects liver against ischemia reperfusion injury by inhibiting nuclear factor kappa B activation in kupffer cells Journal of Surgical Research 187 2014 653 659
    • (2014) Journal of Surgical Research , vol.187 , pp. 653-659
    • Qiao, Y.L.1    Qian, J.M.2    Wang, F.R.3    Ma, Z.Y.4    Wang, Q.W.5
  • 30
    • 1442351151 scopus 로고    scopus 로고
    • Preliminary evaluation of the antihepatotoxic activity of Kamilari, a polyherbal formulation
    • M.G. Rajesh, and M.S. Latha Preliminary evaluation of the antihepatotoxic activity of Kamilari, a polyherbal formulation Journal of Ethnopharmacology 91 2004 99 104
    • (2004) Journal of Ethnopharmacology , vol.91 , pp. 99-104
    • Rajesh, M.G.1    Latha, M.S.2
  • 31
    • 84896889977 scopus 로고    scopus 로고
    • Cytokines as potential biomarkers of liver toxicity induced by Dioscorea bulbifera L
    • Y.C. Sheng, Y.B. Ma, Z.P. Deng, and Z.T. Wang Cytokines as potential biomarkers of liver toxicity induced by Dioscorea bulbifera L Bioscience Trends 8 2014 32 37
    • (2014) Bioscience Trends , vol.8 , pp. 32-37
    • Sheng, Y.C.1    Ma, Y.B.2    Deng, Z.P.3    Wang, Z.T.4
  • 33
    • 84860264787 scopus 로고    scopus 로고
    • Approach to a patient with elevated serum alkaline phosphatase
    • A. Siddique, and K.V. Kowdley Approach to a patient with elevated serum alkaline phosphatase Clinics in Liver Disease 16 2012 199 229
    • (2012) Clinics in Liver Disease , vol.16 , pp. 199-229
    • Siddique, A.1    Kowdley, K.V.2
  • 35
    • 84923855874 scopus 로고    scopus 로고
    • Scutellarin protects against lipopolysaccharide-induced acute lung injury via inhibition of NF-kappaB activation in mice
    • Z.H. Tan, L.H. Yu, H.L. Wei, and G.T. Liu Scutellarin protects against lipopolysaccharide-induced acute lung injury via inhibition of NF-kappaB activation in mice Phytomedicine 17 2010 63 68
    • (2010) Phytomedicine , vol.17 , pp. 63-68
    • Tan, Z.H.1    Yu, L.H.2    Wei, H.L.3    Liu, G.T.4
  • 36
    • 33846352009 scopus 로고    scopus 로고
    • The protective action of scutellarin against immunological liver injury induced by concanavalin A and its effect on pro-inflammatory cytokines in mice
    • Z.H. Tan, L.H. Yu, H.L. Wei, and G.T. Liu The protective action of scutellarin against immunological liver injury induced by concanavalin A and its effect on pro-inflammatory cytokines in mice Journal of Pharmacy Pharmacology 59 2007 115 121
    • (2007) Journal of Pharmacy Pharmacology , vol.59 , pp. 115-121
    • Tan, Z.H.1    Yu, L.H.2    Wei, H.L.3    Liu, G.T.4
  • 37
    • 0017831243 scopus 로고
    • Glutathione peroxidase and hydroperoxides
    • A. Tappel Glutathione peroxidase and hydroperoxides Methods in Enzymology 52 1978 506 513
    • (1978) Methods in Enzymology , vol.52 , pp. 506-513
    • Tappel, A.1
  • 38
    • 1342264208 scopus 로고    scopus 로고
    • Effects of acute lindane intoxication and thyroid hormone administration in relation to nuclear factor-kappaB activation, tumor necrosis factor-alpha expression, and kupffer cell function in the rat
    • C. Valencia, P. Cornejio, P. Romanque, G. Tapia, P. Varela, L.A. Videla, and V. Fernandez Effects of acute lindane intoxication and thyroid hormone administration in relation to nuclear factor-kappaB activation, tumor necrosis factor-alpha expression, and kupffer cell function in the rat Toxicology Letters 148 2004 21 28
    • (2004) Toxicology Letters , vol.148 , pp. 21-28
    • Valencia, C.1    Cornejio, P.2    Romanque, P.3    Tapia, G.4    Varela, P.5    Videla, L.A.6    Fernandez, V.7
  • 40
    • 77956896340 scopus 로고    scopus 로고
    • Study of the hepatotoxicity induced by Dioscorea bulbifera L. Rhizome in mice
    • J.M. Wang, L.L. Ji, H. Liu, and Z.T. Wang Study of the hepatotoxicity induced by Dioscorea bulbifera L. rhizome in mice Bioscience Trends 4 2010 79 85
    • (2010) Bioscience Trends , vol.4 , pp. 79-85
    • Wang, J.M.1    Ji, L.L.2    Liu, H.3    Wang, Z.T.4
  • 42
    • 79956260639 scopus 로고    scopus 로고
    • Neuroprotection of Scutellarin is mediated by inhibition of microglial inflammatory activation
    • S. Wang, H. Wang, H. Guo, L. Kang, X. Gao, and L. Hu Neuroprotection of Scutellarin is mediated by inhibition of microglial inflammatory activation Neuroscience 185 2011 150 160
    • (2011) Neuroscience , vol.185 , pp. 150-160
    • Wang, S.1    Wang, H.2    Guo, H.3    Kang, L.4    Gao, X.5    Hu, L.6
  • 43
    • 84885631563 scopus 로고    scopus 로고
    • Scutellarin-induced apoptosis in HepG2 hepatocellular carcinoma cells via a STAT3 pathway
    • H. Xu, and S. Zhang Scutellarin-induced apoptosis in HepG2 hepatocellular carcinoma cells via a STAT3 pathway Phytotherapy Research 27 2013 1524 1528
    • (2013) Phytotherapy Research , vol.27 , pp. 1524-1528
    • Xu, H.1    Zhang, S.2
  • 44
    • 77956898289 scopus 로고    scopus 로고
    • Protective effects of chlorogenic acid on acute hepatotoxicity induced by lipopolysaccharide in mice
    • Y.X. Xu, J.W. Chen, X. Yu, W.W. Tao, F.R. Jiang, Z.M. Yin, and C. Liu Protective effects of chlorogenic acid on acute hepatotoxicity induced by lipopolysaccharide in mice Inflammation Research 59 2010 871 877
    • (2010) Inflammation Research , vol.59 , pp. 871-877
    • Xu, Y.X.1    Chen, J.W.2    Yu, X.3    Tao, W.W.4    Jiang, F.R.5    Yin, Z.M.6    Liu, C.7
  • 45
    • 0141957504 scopus 로고    scopus 로고
    • Effects of scutellarin on liver function after brain ischemia/reperfusion in rats
    • X.F. Yang, W. He, W.H. Lu, and F.D. Zeng Effects of scutellarin on liver function after brain ischemia/reperfusion in rats Acta Pharmacologica Sinica 24 2003 1118 1124
    • (2003) Acta Pharmacologica Sinica , vol.24 , pp. 1118-1124
    • Yang, X.F.1    He, W.2    Lu, W.H.3    Zeng, F.D.4
  • 46
    • 0020623020 scopus 로고
    • Interrelation between lipid peroxidation and lysosomal enzyme release in the presence of carbon tetrachloride, cumene hydroperoxide or thioacetamide
    • M. Younes, M. Albrecht, and C.P. Sieqers Interrelation between lipid peroxidation and lysosomal enzyme release in the presence of carbon tetrachloride, cumene hydroperoxide or thioacetamide Research and Communication in Chemistry & Pathology & Pharmacology 40 1983 121 132
    • (1983) Research and Communication in Chemistry & Pathology & Pharmacology , vol.40 , pp. 121-132
    • Younes, M.1    Albrecht, M.2    Sieqers, C.P.3
  • 47


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.